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ONTOLOGY REPORT - ANNOTATIONS

Term:mRNA methyltransferase activity
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Accession:GO:0008174 term browser browse the term
Definition:Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an mRNA molecule.


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mRNA methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mettl8 methyltransferase 8, tRNA N3-cytidine enables
NOT|enables		 ISO (PMID:28655767)
MGI:5903742 (PMID:28655767)
(PMID:34774131)		 RGD PMID:28655767 PMID:34774131 NCBI chr 3:76,140,465...76,271,367
Ensembl chr 3:55,770,167...55,863,676 		JBrowse link
internal mRNA (guanine-N7-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mettl1 methyltransferase 1, tRNA methylguanosine enables ISO
IEA		 (PMID:31031084), (PMID:37379838)
GO_REF:0000107		 RGD
Ensembl		 PMID:31031084 PMID:37379838 GO_REF:0000107 NCBI chr 7:64,750,189...64,754,531
Ensembl chr 7:62,864,853...62,869,202 		JBrowse link
mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pcif1 phosphorylated CTD interacting factor 1 enables ISO
IEA		 (PMID:30467178), (PMID:30487554), (PMID:31279658), (PMID:31279659), (PMID:32814042), (PMID:33428944)
(PMID:30487554)
GO_REF:0000002		 RGD
InterPro		 PMID:30467178 PMID:30487554 PMID:31279658 PMID:31279659 PMID:32814042 More... GO_REF:0000002 NCBI chr 3:174,033,471...174,046,403
Ensembl chr 3:153,614,147...153,627,079 		JBrowse link
mRNA (adenine-N1-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trmt61a tRNA methyltransferase 61A enables ISO
IEA
ISS		 (PMID:29072297), (PMID:29107537)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:29072297 PMID:29107537 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:136,558,417...136,564,411
Ensembl chr 6:130,737,219...130,743,243 		JBrowse link
mRNA (cytidine-5-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nsun2 NOP2/Sun RNA methyltransferase 2 enables ISO
IEA		 (PMID:22395603), (PMID:28418038), (PMID:31358969)
(PMID:23871666)
GO_REF:0000107		 RGD
Ensembl		 PMID:22395603 PMID:23871666 PMID:28418038 PMID:31358969 GO_REF:0000107 NCBI chr 1:35,490,583...35,514,839
Ensembl chr 1:33,662,139...33,685,862 		JBrowse link
G Nsun4 NOP2/Sun RNA methyltransferase 4 enables ISO
IEA		 (PMID:39019044)
GO_REF:0000107		 RGD
Ensembl		 PMID:39019044 GO_REF:0000107 NCBI chr 5:134,749,024...134,773,630
Ensembl chr 5:129,512,307...129,532,423
Ensembl chr 5:129,512,307...129,532,423 		JBrowse link
mRNA (nucleoside-2'-O-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmtr1 cap methyltransferase 1 enables ISS
ISO
IEA
IBA		 GO_REF:0000024
(PMID:20713356), (PMID:21310715)
GO_REF:0000003
GO_REF:0000117
GO_REF:0000033
GO_REF:0000104		 UniProt
RGD
GO_Central		 PMID:20713356 PMID:21310715 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 GO_REF:0000117 NCBI chr20:7,724,286...7,784,787
Ensembl chr20:7,709,713...7,766,302 		JBrowse link
G Cmtr2 cap methyltransferase 2 enables ISO
IBA
IEA		 (PMID:21310715)
GO_REF:0000033
GO_REF:0000117
GO_REF:0000107		 RGD
GO_Central
UniProt
Ensembl		 PMID:21310715 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr19:55,100,135...55,106,966
Ensembl chr19:38,190,642...38,197,804 		JBrowse link
mRNA 5'-cap (guanine-N7-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnmt RNA (guanine-7-) methyltransferase enables ISS
IEA
IBA
ISO		 GO_REF:0000024
GO_REF:0000003
GO_REF:0000002
GO_REF:0000033
(PMID:22099306), (PMID:27422871), (PMID:9790902)		 UniProt
InterPro
GO_Central
RGD		 PMID:9790902 PMID:22099306 PMID:27422871 GO_REF:0000002 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 NCBI chr18:64,156,067...64,179,601
Ensembl chr18:61,886,292...61,909,775 		JBrowse link
mRNA m(6)A methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mettl14 methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit NOT|enables ISO (PMID:27627798)
(PMID:24316715)
(PMID:24394384), (PMID:31340148)		 RGD PMID:24316715 PMID:24394384 PMID:27627798 PMID:31340148 NCBI chr 2:214,215,165...214,231,412
Ensembl chr 2:211,530,602...211,546,821 		JBrowse link
G Mettl16 methyltransferase 16, RNA N6-adenosine enables ISO
IEA		 (PMID:28525753), (PMID:30197297), (PMID:30197299), (PMID:33428944)
GO_REF:0000107
GO_REF:0000003
(PMID:29262316)		 RGD
Ensembl
UniProt		 PMID:28525753 PMID:29262316 PMID:30197297 PMID:30197299 PMID:33428944 GO_REF:0000003 GO_REF:0000107 NCBI chr10:60,139,317...60,185,438
Ensembl chr10:59,640,972...59,687,061 		JBrowse link
G Mettl3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit enables ISO
IEA
IBA		 (PMID:22575960), (PMID:24284625), (PMID:24316715), (PMID:27281194), (PMID:27373337), (PMID:27627798), (PMID:28297716), (PMID:9409616)
GO_REF:0000002
GO_REF:0000117
GO_REF:0000107
(PMID:24209618), (PMID:24394384), (PMID:25456834), (PMID:25569111), (PMID:28792938), (PMID:33020597)
GO_REF:0000033		 RGD
InterPro
UniProt
Ensembl
GO_Central		 PMID:9409616 PMID:22575960 PMID:24209618 PMID:24284625 PMID:24316715 More... GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr15:27,476,659...27,491,134
Ensembl chr15:25,003,172...25,014,041 		JBrowse link
G Tmt1a thiol methyltransferase 1A enables ISO
IEA		 (PMID:34226523)
GO_REF:0000107		 RGD
Ensembl		 PMID:34226523 GO_REF:0000107 NCBI chr 7:133,330,141...133,377,172
Ensembl chr 7:131,451,641...131,460,154 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21100
    catalytic activity 6213
      catalytic activity, acting on a nucleic acid 651
        catalytic activity, acting on RNA 411
          RNA methyltransferase activity 64
            mRNA methyltransferase activity 13
              internal mRNA (guanine-N7-)-methyltransferase activity 1
              mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity 1
              mRNA (adenine-N1-)-methyltransferase activity 1
              mRNA (cytidine-5-)-methyltransferase activity 2
              mRNA (nucleoside-2'-O-)-methyltransferase activity 2
              mRNA 5'-cap (guanine-N7-)-methyltransferase activity 1
              mRNA m(6)A methyltransferase activity 4
Path 2
Term Annotations click to browse term
  molecular_function 21100
    catalytic activity 6213
      transferase activity 2476
        transferase activity, transferring one-carbon groups 215
          methyltransferase activity 204
            RNA methyltransferase activity 64
              mRNA methyltransferase activity 13
                internal mRNA (guanine-N7-)-methyltransferase activity 1
                mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity 1
                mRNA (adenine-N1-)-methyltransferase activity 1
                mRNA (cytidine-5-)-methyltransferase activity 2
                mRNA (nucleoside-2'-O-)-methyltransferase activity 2
                mRNA 5'-cap (guanine-N7-)-methyltransferase activity 1
                mRNA m(6)A methyltransferase activity 4
paths to the root