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ONTOLOGY REPORT - ANNOTATIONS

Term:alcohol dehydrogenase (NADP+) activity
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Accession:GO:0008106 term browser browse the term
Definition:Catalysis of the reaction: an alcohol + NADP+ = an aldehyde or ketone + NADPH + H+.
Synonyms:exact_synonym: NADP-aldehyde reductase activity
 related_synonym: aldehyde reductase (NADPH) activity
 xref: EC:1.1.1.2


show annotations for term's descendants           Sort by:
alcohol dehydrogenase (NADP+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1a1 aldo-keto reductase family 1 member A1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 enables ISO (PMID:19013440) RGD PMID:19013440 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 enables ISO
ISS		 (PMID:1737758)
GO_REF:0000024		 RGD
UniProt		 PMID:1737758 GO_REF:0000024 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681 		JBrowse link
G Rdh14 retinol dehydrogenase 14 enables ISO (PMID:25533474) RGD PMID:25533474 NCBI chr 6:33,156,569...33,161,712
Ensembl chr 6:33,156,569...33,161,712 		JBrowse link
aldose reductase (NADPH) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide enables ISO (PMID:10514444) RGD PMID:10514444 NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591 		JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 enables ISO
IBA		 (PMID:14667815), (PMID:15769935)
GO_REF:0000033		 RGD
GO_Central		 PMID:14667815 PMID:15769935 GO_REF:0000033 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 enables IDA
IBA
ISO		 GO_REF:0000033
(PMID:17727625), (PMID:7851421)
(PMID:1420136), (PMID:2112546), (PMID:8435445), (PMID:8645003)		 GO_Central
RGD		 PMID:1420136 PMID:2112546 PMID:7851421 PMID:8435445 PMID:8645003 More... GO_REF:0000033, RGD:1626085 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 enables IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:20709016 GO_REF:0000033, RGD:6903952 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Akr1b7 aldo-keto reductase family 1, member B7 enables TAS
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:12193556 GO_REF:0000033, RGD:628357 NCBI chr 4:63,053,560...63,100,934
Ensembl chr 4:63,076,800...63,089,502 		JBrowse link
G Akr1b8 aldo-keto reductase family 1, member B8 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:62,997,241...63,009,815
Ensembl chr 4:62,997,161...63,010,097 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 enables ISO
IBA		 (PMID:21232532)
GO_REF:0000033		 RGD
GO_Central		 PMID:21232532 GO_REF:0000033 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akr1c12 aldo-keto reductase family 1, member C12 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:66,045,376...66,061,496
Ensembl chr17:66,045,378...66,108,329 		JBrowse link
G Akr1c12l1 aldo-keto reductase family 1, member C12-like 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:65,937,834...65,948,344
Ensembl chr17:65,937,814...65,997,595
Ensembl chr17:65,937,814...65,997,595 		JBrowse link
G Akr1c13 aldo-keto reductase family 1, member C13 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:65,964,186...65,997,598
Ensembl chr17:65,964,975...65,997,591 		JBrowse link
G Akr1c14 aldo-keto reductase family 1, member C14 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:66,156,286...66,173,277
Ensembl chr17:66,156,288...66,173,277 		JBrowse link
G Akr1c15 aldo-keto reductase family 1, member C15 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:66,181,493...66,208,090
Ensembl chr17:66,181,493...66,208,061 		JBrowse link
G Akr1c19 aldo-keto reductase family 1, member C19 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:66,001,358...66,027,226
Ensembl chr17:66,004,002...66,025,047 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 enables ISO
IBA		 (PMID:21232532)
GO_REF:0000033		 RGD
GO_Central		 PMID:21232532 GO_REF:0000033 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 enables IDA
IBA
ISO		 GO_REF:0000033
(PMID:21232532)		 GO_Central
RGD		 PMID:21232532 PMID:8977402 GO_REF:0000033, RGD:10053609 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G AKR1C3l1 aldo-keto reductase family 1 member C3-like 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:65,847,580...65,881,488
Ensembl chr17:65,835,634...65,881,488 		JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372 		JBrowse link
G Akr1e2 aldo-keto reductase family 1, member E2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:65,735,909...65,750,441
Ensembl chr17:65,735,943...65,750,441 		JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 IDA RGD PMID:12071861 RGD:625492 NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909 		JBrowse link
all-trans-retinol dehydrogenase (NADP+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b1 aldo-keto reductase family 1 member B1 enables IEA GO_REF:0000003
GO_REF:0000116		 UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 enables IDA
ISO		 (PMID:12732097) RGD PMID:12732097 PMID:20709016 RGD:6903952 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Dhrs3 dehydrogenase/reductase 3 enables ISO MGI:5007106 (PMID:24005908) RGD PMID:24005908 NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417 		JBrowse link
G Dhrs4 dehydrogenase/reductase 4 enables ISO
ISS		 (PMID:12604222)
GO_REF:0000024		 RGD
UniProt		 PMID:12604222 GO_REF:0000024 NCBI chr15:28,966,544...28,978,135
Ensembl chr15:28,966,553...28,978,127 		JBrowse link
G Dhrs7 dehydrogenase/reductase 7 enables ISO (PMID:26466768) RGD PMID:26466768 NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892 		JBrowse link
G Rdh10 retinol dehydrogenase 10 enables IEA GO_REF:0000116
GO_REF:0000003		 RHEA
UniProt		 GO_REF:0000003 GO_REF:0000116 NCBI chr 5:3,186,671...3,215,572
Ensembl chr 5:3,188,445...3,215,572 		JBrowse link
G Rdh11 retinol dehydrogenase 11 enables ISO (PMID:12226107), (PMID:12807874) RGD PMID:12226107 PMID:12807874 NCBI chr 6:97,979,377...97,995,252
Ensembl chr 6:97,979,378...97,995,252 		JBrowse link
G Rdh12 retinol dehydrogenase 12 enables ISO (PMID:12226107) RGD PMID:12226107 NCBI chr 6:98,015,465...98,028,388
Ensembl chr 6:98,015,465...98,028,388 		JBrowse link
G Rdh13 retinol dehydrogenase 13 enables ISO
IBA		 (PMID:18039331)
GO_REF:0000033		 RGD
GO_Central		 PMID:18039331 GO_REF:0000033 NCBI chr 1:69,373,014...69,401,454
Ensembl chr 1:69,373,113...69,400,908 		JBrowse link
G Rdh14 retinol dehydrogenase 14 enables ISO (PMID:12435598)
(PMID:12226107)		 RGD PMID:12226107 PMID:12435598 NCBI chr 6:33,156,569...33,161,712
Ensembl chr 6:33,156,569...33,161,712 		JBrowse link
G Rdh8 retinol dehydrogenase 8 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 8:19,353,191...19,360,462
Ensembl chr 8:19,353,191...19,360,462 		JBrowse link
carbonyl reductase (NADPH) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbr1 carbonyl reductase 1 enables IDA
IEA
IBA
ISO
ISS		 GO_REF:0000104
GO_REF:0000033
(PMID:18449627), (PMID:1921984)
GO_REF:0000024		 UniProt
GO_Central
RGD		 PMID:1921984 PMID:18449627 PMID:12396270 PMID:7705364 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104, RGD:634703, RGD:69801 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393 		JBrowse link
G Cbr1l1 carbonyl reductase 1 like 1 enables IEA
IBA		 GO_REF:0000104
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000104 NCBI chr11:32,876,563...32,884,234
Ensembl chr11:32,857,991...32,895,275 		JBrowse link
G Cbr1l2 carbonyl reductase 1 like 2 enables IBA
IEA		 GO_REF:0000033
GO_REF:0000104		 GO_Central
UniProt		 GO_REF:0000033 GO_REF:0000104 NCBI chr11:32,892,640...32,895,277
Ensembl chr11:32,857,991...32,895,275 		JBrowse link
G Cbr1l3 carbonyl reductase 1 like 3 enables IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr11:32,985,136...32,992,000
Ensembl chr11:32,985,707...32,992,000 		JBrowse link
G Cbr2 carbonyl reductase 2 enables IBA
ISO		 GO_REF:0000033
(PMID:7705352)		 GO_Central
RGD		 PMID:7705352 GO_REF:0000033 NCBI chr10:106,008,535...106,012,838
Ensembl chr10:105,991,589...106,013,001 		JBrowse link
G Cbr2l1 carbonyl reductase 2 like 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:106,033,250...106,036,852
Ensembl chr10:106,033,255...106,036,919 		JBrowse link
G Cbr3 carbonyl reductase 3 enables IDA
IBA
ISO		 GO_REF:0000033
(PMID:18493841)		 GO_Central
RGD		 PMID:18493841 PMID:18983987 GO_REF:0000033, RGD:2316293 NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875 		JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:106,006,404...106,008,293 JBrowse link
G Dhrs1 dehydrogenase/reductase 1 enables ISO (PMID:30031147) RGD PMID:30031147 NCBI chr15:29,236,522...29,243,807
Ensembl chr15:29,236,522...29,243,838 		JBrowse link
G Dhrs2 dehydrogenase/reductase 2 enables ISO
IBA		 (PMID:16685466)
GO_REF:0000033		 RGD
GO_Central		 PMID:16685466 GO_REF:0000033 NCBI chr15:28,688,881...28,703,646
Ensembl chr15:28,688,940...28,703,644 		JBrowse link
G Dhrs2l1 dehydrogenase/reductase member 2 like 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:28,635,197...28,638,087
Ensembl chr15:28,635,197...28,638,087 		JBrowse link
G Dhrs4 dehydrogenase/reductase 4 enables ISO
IBA		 (PMID:18571493), (PMID:19056333)
GO_REF:0000033
(PMID:23128527)		 RGD
GO_Central		 PMID:18571493 PMID:19056333 PMID:23128527 GO_REF:0000033 NCBI chr15:28,966,544...28,978,135
Ensembl chr15:28,966,553...28,978,127 		JBrowse link
G Dhrs7 dehydrogenase/reductase 7 enables ISO (PMID:24246760), (PMID:26466768), (PMID:28457967), (PMID:28687384) RGD PMID:24246760 PMID:26466768 PMID:28457967 PMID:28687384 NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892 		JBrowse link
G Kcnab1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 enables IEA GO_REF:0000116 RHEA GO_REF:0000116 NCBI chr 2:149,137,025...149,603,540
Ensembl chr 2:149,137,041...149,603,534 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20634
    catalytic activity 6032
      oxidoreductase activity 854
        oxidoreductase activity, acting on CH-OH group of donors 161
          oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 152
            alcohol dehydrogenase [NAD(P)+] activity 63
              aldo-keto reductase (NADPH) activity 45
                alcohol dehydrogenase (NADP+) activity 41
                  2-methylbutanal reductase (NADPH) activity 0
                  3-methylbutanal reductase (NADPH) activity 0
                  aldose reductase (NADPH) activity + 19
                  all-trans-retinol dehydrogenase (NADP+) activity 11
                  carbonyl reductase (NADPH) activity 14
paths to the root