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ONTOLOGY REPORT - ANNOTATIONS

Term:cyclin/CDK positive transcription elongation factor complex
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Accession:GO:0008024 term browser browse the term
Definition:A transcription elongation factor complex that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme. Contains a cyclin and a cyclin-dependent protein kinase catalytic subunit.
Comment:See also the cellular component terms 'cyclin-dependent protein kinase activating kinase holoenzyme complex ; GO:0019907' and 'DNA-directed RNA polymerase II, holoenzyme ; GO:0016591'.
Synonyms:related_synonym: positive transcription elongation factor complex b


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cyclin/CDK positive transcription elongation factor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brd4 bromodomain containing 4 part_of ISO (PMID:23752591) RGD PMID:23752591 NCBI chr 7:11,866,997...11,946,575
Ensembl chr 7:11,866,997...11,946,923 		JBrowse link
G Ccnk cyclin K part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:132,854,428...132,877,604
Ensembl chr 6:132,854,700...132,877,602 		JBrowse link
G Ccnt1 cyclin T1 part_of ISO (PMID:15905409), (PMID:18566585), (PMID:9499409) RGD PMID:9499409 PMID:15905409 PMID:18566585 NCBI chr 7:131,566,176...131,596,988
Ensembl chr 7:131,566,176...131,596,938 		JBrowse link
G Ccnt2 cyclin T2 part_of IBA
ISO
IEA 		GO_REF:0000033
(PMID:9499409)
GO_REF:0000107 		GO_Central
RGD
Ensembl		 PMID:9499409 GO_REF:0000033 GO_REF:0000107 NCBI chr13:41,804,007...41,845,641
Ensembl chr13:41,804,046...41,844,488 		JBrowse link
G Cdk12 cyclin-dependent kinase 12 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:83,697,174...83,793,676
Ensembl chr10:83,767,206...83,777,183
Ensembl chr10:83,767,206...83,777,183 		JBrowse link
G Cdk13 cyclin-dependent kinase 13 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:51,945,975...52,040,218
Ensembl chr17:51,946,701...52,037,257 		JBrowse link
G Cdk9 cyclin-dependent kinase 9 part_of ISS
ISO
IEA 		GO_REF:0000024
(PMID:23752591)
GO_REF:0000107
(PMID:15905409), (PMID:18566585), (PMID:9499409) 		UniProt
RGD
Ensembl		 PMID:9499409 PMID:15905409 PMID:18566585 PMID:23752591 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:36,394,168...36,399,016
Ensembl chr 3:36,394,169...36,399,528 		JBrowse link
G Rb1 RB transcriptional corepressor 1 located_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:12037672)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:12037672 GO_REF:0000024 GO_REF:0000107 NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857 		JBrowse link
G Snw1 SNW domain containing 1 located_in ISO (PMID:15905409) RGD PMID:15905409 NCBI chr 6:112,826,374...112,850,459
Ensembl chr 6:112,826,381...112,858,180 		JBrowse link
P-TEFb complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnt1 cyclin T1 part_of ISO (PMID:18483487), (PMID:28431135), (PMID:29849146), (PMID:30134174) RGD PMID:18483487 PMID:28431135 PMID:29849146 PMID:30134174 NCBI chr 7:131,566,176...131,596,988
Ensembl chr 7:131,566,176...131,596,938 		JBrowse link
G Cdk9 cyclin-dependent kinase 9 part_of ISS
ISO
IEA 		GO_REF:0000024
(PMID:18483487), (PMID:30134174)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:18483487 PMID:30134174 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:36,394,168...36,399,016
Ensembl chr 3:36,394,169...36,399,528 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19485
    protein-containing complex 6265
      nuclear protein-containing complex 1368
        carboxy-terminal domain protein kinase complex 21
          cyclin/CDK positive transcription elongation factor complex 9
            CTDK-1 complex 0
            P-TEFb complex 2
Path 2
Term Annotations click to browse term
  cellular_component 19485
    cellular anatomical structure 19353
      organelle 13686
        membrane-bounded organelle 12471
          intracellular membrane-bounded organelle 11899
            nucleus 7471
              nuclear lumen 4263
                nucleoplasm 3734
                  transcription elongation factor complex 70
                    cyclin/CDK positive transcription elongation factor complex 9
                      CTDK-1 complex 0
                      P-TEFb complex 2
paths to the root