ONTOLOGY REPORT - ANNOTATIONS
Term: cyclin/CDK positive transcription elongation factor complex
Accession: GO:0008024
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Definition: A transcription elongation factor complex that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme. Contains a cyclin and a cyclin-dependent protein kinase catalytic subunit.
Comment: See also the cellular component terms 'cyclin-dependent protein kinase activating kinase holoenzyme complex ; GO:0019907' and 'DNA-directed RNA polymerase II, holoenzyme ; GO:0016591'.
Synonyms: related_synonym: positive transcription elongation factor complex b
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Brd4
bromodomain containing 4
part_of
ISO
(PMID:23752591)
RGD
PMID:23752591
NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539
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Ccnk
cyclin K
part_of
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 6:127,090,115...127,113,195
Ensembl chr 6:127,090,569...127,113,191
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Ccnt1
cyclin T1
part_of
IBA ISO
GO_REF:0000033 (PMID:15905409), (PMID:18566585), (PMID:9499409)
GO_Central RGD
PMID:9499409 PMID:15905409 PMID:18566585
GO_REF:0000033
NCBI chr 7:129,687,146...129,718,080
Ensembl chr 7:129,691,209...129,717,871
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Ccnt2
cyclin T2
part_of
IBA ISO
GO_REF:0000033 (PMID:9499409)
GO_Central RGD
PMID:9499409
GO_REF:0000033
NCBI chr13:39,251,573...39,293,172
Ensembl chr13:39,251,573...39,292,019
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Cdk12
cyclin-dependent kinase 12
part_of
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr10:83,201,177...83,256,906
Ensembl chr10:83,201,211...83,280,888 Ensembl chr10:83,201,211...83,280,888
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Cdk13
cyclin-dependent kinase 13
part_of
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr17:47,251,145...47,344,675
Ensembl chr17:47,251,163...47,341,721
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Cdk9
cyclin-dependent kinase 9
part_of
ISS ISO
GO_REF:0000024 (PMID:15905409), (PMID:18566585), (PMID:9499409) (PMID:23752591)
UniProt RGD
PMID:9499409 PMID:15905409 PMID:18566585 PMID:23752591
GO_REF:0000024
NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410
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Rb1
RB transcriptional corepressor 1
part_of located_in
IEA ISS ISO
GO_REF:0000107 GO_REF:0000024 (PMID:12037672)
Ensembl UniProt RGD
PMID:12037672
GO_REF:0000024 GO_REF:0000107
NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
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Snw1
SNW domain containing 1
located_in
ISO
(PMID:15905409)
RGD
PMID:15905409
NCBI chr 6:107,095,450...107,119,536
Ensembl chr 6:107,095,457...107,119,536
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Ccnt1
cyclin T1
part_of
ISO
(PMID:18483487), (PMID:28431135), (PMID:29849146), (PMID:30134174)
RGD
PMID:18483487 PMID:28431135 PMID:29849146 PMID:30134174
NCBI chr 7:129,687,146...129,718,080
Ensembl chr 7:129,691,209...129,717,871
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Cdk9
cyclin-dependent kinase 9
part_of
ISS ISO IEA
GO_REF:0000024 (PMID:18483487), (PMID:30134174) GO_REF:0000107
UniProt RGD Ensembl
PMID:18483487 PMID:30134174
GO_REF:0000024 GO_REF:0000107
NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410
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