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ONTOLOGY REPORT - ANNOTATIONS

Term:phospholipase C-activating G protein-coupled receptor signaling pathway
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Accession:GO:0007200 term browser browse the term
Definition:A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of phospholipase C (PLC) and a subsequent increase in the intracellular concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG). IP3 regulates the opening of calcium channels in intracellular calcium store, leading to the release of calcium into the cytosol. Calcium and DAG activate protein kinase C (PKC), which in turn activates downstream effectors.
Synonyms:exact_synonym: G protein signaling, coupled to IP3 second messenger (phospholipase C activating);   G protein signalling, coupled to IP3 second messenger (phospholipase C activating);   G-protein coupled receptor signaling pathway coupled to IP3 second messenger;   PLC-activating GPCR signaling pathway;   protein kinase C-activating G protein-coupled receptor signaling pathway
 related_synonym: activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger


show annotations for term's descendants           Sort by:
phospholipase C-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:24367707) RGD PMID:24367707 NCBI chr13:68,673,702...68,770,846
Ensembl chr13:68,673,722...68,839,742 		JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:21724588)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:21724588 GO_REF:0000024 GO_REF:0000107 NCBI chr19:10,003,963...10,041,122
Ensembl chr19:10,003,975...10,041,108 		JBrowse link
G Adora2a adenosine A2a receptor IDA in PC12 cells, PKCs epsilon and zeta activated after short-term activation of Adora2a RGD PMID:12590138 RGD:1625697 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Adra1a adrenoceptor alpha 1A involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
(PMID:9590558)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:9590558 GO_REF:0000033 GO_REF:0000107 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500 		JBrowse link
G Adra1b adrenoceptor alpha 1B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919 		JBrowse link
G Adra1d adrenoceptor alpha 1D involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:118,793,356...118,809,354
Ensembl chr 3:118,793,346...118,809,354 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a involved_in IDA
ISO		 (PMID:1567413) RGD PMID:1567413 PMID:11906170 RGD:70819 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Ano1 anoctamin 1 involved_in ISO (PMID:22634729) RGD PMID:22634729 NCBI chr 1:199,751,439...199,900,099
Ensembl chr 1:199,751,439...199,900,069 		JBrowse link
G Avpr1b arginine vasopressin receptor 1B involved_in ISO
IEA		 (PMID:9322919)
GO_REF:0000107		 RGD
Ensembl		 PMID:9322919 GO_REF:0000107 NCBI chr13:43,046,531...43,059,046
Ensembl chr13:43,046,267...43,057,792 		JBrowse link
G C3ar1 complement C3a receptor 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:156,074,747...156,084,680
Ensembl chr 4:156,075,389...156,084,701 		JBrowse link
G C5ar1 complement C5a receptor 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:76,948,622...76,959,826 JBrowse link
G C5ar2 complement C5a receptor 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:76,930,381...76,945,432
Ensembl chr 1:76,930,383...76,959,517 		JBrowse link
G Calca calcitonin-related polypeptide alpha involved_in ISO (PMID:9685362) RGD PMID:9685362 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Casr calcium-sensing receptor IDA RGD PMID:22192592 RGD:7207059 NCBI chr11:64,235,251...64,304,811
Ensembl chr11:64,235,251...64,304,811 		JBrowse link
G Cck cholecystokinin IDA RGD PMID:12496267 RGD:1626097 NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084 		JBrowse link
G Cckbr cholecystokinin B receptor involved_in ISO
IBA
IEA		 (PMID:7681836)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:7681836 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881 		JBrowse link
G Cmklr1 chemerin chemokine-like receptor 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:42,974,462...43,027,321
Ensembl chr12:42,974,410...43,028,129 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 IDA in transfected HEK cells RGD PMID:15932935 RGD:1626241 NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,040,203...89,083,481 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:19439178 RGD:5130951 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in ISO (PMID:10187784) RGD PMID:10187784 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 involved_in ISO (PMID:10438939) RGD PMID:10438939 NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425 		JBrowse link
G Dgka diacylglycerol kinase, alpha involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:1,148,734...1,175,324
Ensembl chr 7:1,148,735...1,175,110 		JBrowse link
G Dgkb diacylglycerol kinase, beta involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:54,640,948...55,397,210
Ensembl chr 6:54,641,614...55,397,043 		JBrowse link
G Dgkd diacylglycerol kinase, delta involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:88,516,686...88,607,349
Ensembl chr 9:88,516,715...88,607,345 		JBrowse link
G Dgke diacylglycerol kinase epsilon involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:73,853,030...73,877,334
Ensembl chr10:73,855,583...73,877,100 		JBrowse link
G Dgkg diacylglycerol kinase, gamma involved_in TAS
IEA		 GO_REF:0000002 InterPro
RGD		 PMID:7809169 GO_REF:0000002, RGD:1298876 NCBI chr11:78,384,212...78,579,158
Ensembl chr11:78,384,458...78,577,212 		JBrowse link
G Dgkh diacylglycerol kinase, eta involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr15:53,981,079...54,150,470
Ensembl chr15:53,991,481...54,150,706 		JBrowse link
G Dgki diacylglycerol kinase, iota involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:65,410,878...65,872,733
Ensembl chr 4:65,420,108...65,872,733 		JBrowse link
G Dgkk diacylglycerol kinase kappa involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:15,581,991...15,713,814
Ensembl chr  X:15,583,572...15,712,987 		JBrowse link
G Dgkq diacylglycerol kinase, theta involved_in ISO (PMID:15632189) RGD PMID:15632189 NCBI chr14:1,059,125...1,073,131
Ensembl chr14:1,059,170...1,073,131 		JBrowse link
G Dgkz diacylglycerol kinase zeta involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:77,904,149...77,946,114
Ensembl chr 3:77,904,150...77,946,099 		JBrowse link
G Drd2 dopamine receptor D2 involved_in ISO (PMID:1331329) RGD PMID:1331329 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Edn1 endothelin 1 acts_upstream_of_or_within ISO (PMID:2542249) RGD PMID:2542249 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Edn2 endothelin 2 IMP RGD PMID:1533364 RGD:1581817 NCBI chr 5:133,751,316...133,756,814
Ensembl chr 5:133,751,217...133,756,814 		JBrowse link
G Ednra endothelin receptor type A IMP RGD PMID:12628492 RGD:728499 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Ednrb endothelin receptor type B IMP RGD PMID:15245872 RGD:1581866 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Esr1 estrogen receptor 1 involved_in IDA PMID:15705806 UniProt PMID:15705806 RGD:8553914 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G F2r coagulation factor II (thrombin) receptor involved_in IMP
IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:20164183)		 GO_Central
Ensembl
RGD		 PMID:20164183 PMID:15145074 PMID:12644441 GO_REF:0000033 GO_REF:0000107, RGD:1582290, RGD:1582293 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870 		JBrowse link
G Ffar1 free fatty acid receptor 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:31664108)		 Ensembl
RGD		 PMID:31664108 GO_REF:0000107 NCBI chr 1:86,111,368...86,112,272
Ensembl chr 1:86,111,368...86,112,272 		JBrowse link
G Ffar2 free fatty acid receptor 2 involved_in ISO (PMID:26075576) RGD PMID:26075576 NCBI chr 1:86,071,855...86,075,049
Ensembl chr 1:86,072,184...86,075,033 		JBrowse link
G Ffar4 free fatty acid receptor 4 involved_in ISO
ISS		 (PMID:27852822)
GO_REF:0000024		 RGD
UniProt		 PMID:27852822 GO_REF:0000024 NCBI chr 1:235,873,576...235,891,597
Ensembl chr 1:235,873,576...235,891,597 		JBrowse link
G Fpr1 formyl peptide receptor 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:22859307)
GO_REF:0000033		 RGD
GO_Central		 PMID:22859307 GO_REF:0000033 NCBI chr 1:58,745,019...58,756,776
Ensembl chr 1:58,747,246...58,756,559 		JBrowse link
G Fpr2 formyl peptide receptor 2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:22859307)		 GO_Central
RGD		 PMID:22859307 GO_REF:0000033 NCBI chr 1:58,776,592...58,785,227
Ensembl chr 1:58,776,752...58,786,019 		JBrowse link
G Fpr2l1 formyl peptide receptor 2 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:59,686,519...59,687,550
Ensembl chr 1:59,686,103...59,716,622 		JBrowse link
G Fpr2l2 formyl peptide receptor 2 like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:58,997,091...58,998,062
Ensembl chr 1:58,968,268...58,999,984 		JBrowse link
G Fpr2l3 formyl peptide receptor 2 like 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:59,181,555...59,182,586
Ensembl chr 1:59,173,577...59,200,760 		JBrowse link
G Fpr3 formyl peptide receptor 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:58,884,427...58,893,472
Ensembl chr 1:58,845,118...58,893,467 		JBrowse link
G Fshr follicle stimulating hormone receptor acts_upstream_of_or_within ISO (PMID:10330114) RGD PMID:10330114 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785 		JBrowse link
G Galr2 galanin receptor 2 involved_in ISO (PMID:9832121) RGD PMID:9832121 NCBI chr10:101,513,689...101,517,176
Ensembl chr10:101,514,471...101,517,176 		JBrowse link
G Gna11 G protein subunit alpha 11 involved_in ISO MGI:95776 (PMID:20440069), (PMID:26075576) RGD PMID:20440069 PMID:26075576 NCBI chr 7:8,163,520...8,177,863
Ensembl chr 7:8,162,750...8,179,812 		JBrowse link
G Gna15 G protein subunit alpha 15 involved_in
acts_upstream_of_or_within		 IMP
IEA
ISO		 GO_REF:0000107
MGI:2152420 (PMID:10629036)		 Ensembl
RGD		 PMID:10629036 PMID:9685675 GO_REF:0000107, RGD:728647 NCBI chr 7:8,184,632...8,205,508
Ensembl chr 7:8,184,861...8,205,508 		JBrowse link
G Gnaq G protein subunit alpha q involved_in IMP
ISO		 MGI:95766 (PMID:20440069), (PMID:20966218), (PMID:26075576), (PMID:37991948)
(PMID:37991948)		 RGD PMID:20440069 PMID:20966218 PMID:26075576 PMID:37991948 PMID:9677408 RGD:1598490 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672 		JBrowse link
G Gnb1 G protein subunit beta 1 acts_upstream_of_or_within ISO (PMID:10570481) RGD PMID:10570481 NCBI chr 5:166,075,508...166,142,223
Ensembl chr 5:166,075,629...166,142,124 		JBrowse link
G Gng13 G protein subunit gamma 13 acts_upstream_of_or_within ISO (PMID:10570481) RGD PMID:10570481 NCBI chr10:14,741,179...14,743,083
Ensembl chr10:14,741,239...14,743,083 		JBrowse link
G Gpr139 G protein-coupled receptor 139 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:16378626)		 GO_Central
RGD		 PMID:16378626 GO_REF:0000033 NCBI chr 1:173,478,137...173,522,615
Ensembl chr 1:173,481,583...173,522,451 		JBrowse link
G Gpr143 G protein-coupled receptor 143 involved_in ISO (PMID:16524428) RGD PMID:16524428 NCBI chr  X:22,002,914...22,027,720
Ensembl chr  X:22,002,914...22,027,715 		JBrowse link
G Gpr157 G protein-coupled receptor 157 involved_in ISS
ISO		 GO_REF:0000024
(PMID:27142930)		 UniProt
RGD		 PMID:27142930 GO_REF:0000024 NCBI chr 5:160,550,703...160,566,432
Ensembl chr 5:160,550,713...160,566,432 		JBrowse link
G Gpr33-ps1 G protein-coupled receptor 33, pseudogene 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:69,474,435...69,475,440
Ensembl chr 6:69,474,435...69,475,440 		JBrowse link
G Gpr4 G protein-coupled receptor 4 involved_in ISO (PMID:20211729) RGD PMID:20211729 NCBI chr 1:78,865,376...78,877,126
Ensembl chr 1:78,865,409...78,876,599 		JBrowse link
G Gpr55 G protein-coupled receptor 55 involved_in ISO (PMID:18757503) RGD PMID:18757503 NCBI chr 9:86,584,906...86,640,601
Ensembl chr 9:86,590,885...86,640,613 		JBrowse link
G Gpr83 G protein-coupled receptor 83 involved_in IEA
ISO		 GO_REF:0000107
(PMID:27117253)		 Ensembl
RGD		 PMID:27117253 GO_REF:0000107 NCBI chr 8:11,693,540...11,704,028
Ensembl chr 8:11,693,540...11,704,028 		JBrowse link
G Grid1 glutamate ionotropic receptor delta type subunit 1 involved_in ISO (PMID:27276689) RGD PMID:27276689 NCBI chr16:10,138,564...10,885,803
Ensembl chr16:10,138,925...10,885,808 		JBrowse link
G Grm1 glutamate metabotropic receptor 1 involved_in TAS
ISO		 PMID:12514208
(PMID:27276689)		 RGD PMID:27276689 PMID:12514208 RGD:728711 NCBI chr 1:5,058,285...5,453,170
Ensembl chr 1:5,058,292...5,453,170 		JBrowse link
G Grm5 glutamate metabotropic receptor 5 involved_in TAS PMID:15758184 UniProt PMID:15758184 RGD:8554618 NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274 		JBrowse link
G Grpr gastrin releasing peptide receptor involved_in ISS
ISO		 GO_REF:0000024
(PMID:26658875)		 UniProt
RGD		 PMID:26658875 GO_REF:0000024 NCBI chr  X:30,998,425...31,038,442
Ensembl chr  X:30,998,416...31,038,442 		JBrowse link
G Hcrt hypocretin neuropeptide precursor IMP RGD PMID:16247802 RGD:1600968 NCBI chr10:85,689,979...85,691,214
Ensembl chr10:85,689,465...85,691,210 		JBrowse link
G Hcrtr2 hypocretin receptor 2 acts_upstream_of_or_within ISO (PMID:15256537) RGD PMID:15256537 NCBI chr 8:76,989,834...77,105,953
Ensembl chr 8:76,989,834...77,105,893 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C involved_in ISS
ISO		 GO_REF:0000024
(PMID:21835345)		 UniProt
RGD		 PMID:21835345 GO_REF:0000024 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Il2 interleukin 2 IMP RGD PMID:7859920 RGD:1600108 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 involved_in ISO (PMID:26075576), (PMID:31664108) RGD PMID:26075576 PMID:31664108 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491 		JBrowse link
G Kiss1 KiSS-1 metastasis-suppressor IDA kisspeptin-10 peptide is 100% identical in rat, mouse and human RGD PMID:11457843 PMID:16222076 RGD:1357971, RGD:1599289 NCBI chr13:44,775,106...44,780,707
Ensembl chr13:44,774,823...44,780,612 		JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor involved_in IDA
ISO
IBA
IEA		 (PMID:10493819)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:10493819 PMID:3026357 GO_REF:0000033 GO_REF:0000107, RGD:2292621 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521 		JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 involved_in ISO (PMID:19733258) RGD PMID:19733258 NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895 		JBrowse link
G Mc1r melanocortin 1 receptor involved_in IEA
ISO		 GO_REF:0000107
(PMID:18292087)		 Ensembl
RGD		 PMID:18292087 GO_REF:0000107 NCBI chr19:51,452,448...51,455,375
Ensembl chr19:51,453,239...51,454,192 		JBrowse link
G Mlnr motilin receptor involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:50,413,570...50,422,842
Ensembl chr19:50,413,580...50,418,770 		JBrowse link
G Myh9 myosin, heavy chain 9 IMP RGD PMID:20068007 RGD:6902910 NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457 		JBrowse link
G Nmur1 neuromedin U receptor 1 involved_in ISO
IEA		 (PMID:10899166)
GO_REF:0000107		 RGD
Ensembl		 PMID:10899166 GO_REF:0000107 NCBI chr 9:87,033,231...87,038,070
Ensembl chr 9:87,033,279...87,036,684 		JBrowse link
G Nmur2 neuromedin U receptor 2 involved_in ISO
IEA		 (PMID:10899166)
GO_REF:0000107		 RGD
Ensembl		 PMID:10899166 GO_REF:0000107 NCBI chr10:40,166,223...40,182,078
Ensembl chr10:40,166,226...40,182,078 		JBrowse link
G Npr3 natriuretic peptide receptor 3 IMP RGD PMID:15044621 RGD:1581459 NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955 		JBrowse link
G Ntsr2 neurotensin receptor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:8795617)		 Ensembl
RGD		 PMID:8795617 GO_REF:0000107 NCBI chr 6:39,424,297...39,431,015
Ensembl chr 6:39,424,324...39,431,014 		JBrowse link
G Oprd1 opioid receptor, delta 1 involved_in IDA PMID:9572309 UniProt PMID:9572309 RGD:8553369 NCBI chr 5:144,306,188...144,340,960
Ensembl chr 5:144,306,188...144,340,960 		JBrowse link
G Oprk1 opioid receptor, kappa 1 involved_in IDA PMID:9572309 UniProt PMID:9572309 RGD:8553369 NCBI chr 5:13,860,016...13,877,823
Ensembl chr 5:13,860,021...13,877,823 		JBrowse link
G Oprl1 opioid related nociceptin receptor 1 involved_in ISO UniProtKB:P30679 (PMID:10571060) RGD PMID:10571060 NCBI chr 3:168,831,934...168,839,920
Ensembl chr 3:168,834,003...168,839,920 		JBrowse link
G Oprm1 opioid receptor, mu 1 involved_in IDA PMID:9572309 UniProt PMID:9572309 RGD:8553369 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Orai1 ORAI calcium release-activated calcium modulator 1 involved_in ISO (PMID:31664108) RGD PMID:31664108 NCBI chr12:33,533,151...33,548,361
Ensembl chr12:33,534,344...33,548,405 		JBrowse link
G P2ry1 purinergic receptor P2Y1 involved_in ISO
IBA
TAS
ISS		 (PMID:9442040)
GO_REF:0000033
PMID:20847060
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:9442040 PMID:20847060 GO_REF:0000024 GO_REF:0000033, RGD:8554370 NCBI chr 2:145,241,975...145,248,186
Ensembl chr 2:145,241,849...145,248,457 		JBrowse link
G P2ry12 purinergic receptor P2Y12 involved_in IMP PMID:18183622
PMID:20091784		 ARUK-UCL PMID:18183622 PMID:20091784 RGD:13673786, RGD:6480646 NCBI chr 2:143,481,468...143,523,340
Ensembl chr 2:143,481,430...143,523,361 		JBrowse link
G P2ry2 purinergic receptor P2Y2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:155,352,050...155,367,423
Ensembl chr 1:155,351,165...155,367,632 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma involved_in ISO (PMID:22728827) RGD PMID:22728827 NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043 		JBrowse link
G Plcb1 phospholipase C beta 1 involved_in ISO MGI:6460327 (PMID:26075576), (PMID:31268747) RGD PMID:26075576 PMID:31268747 NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869 		JBrowse link
G Plcb2 phospholipase C, beta 2 involved_in IDA
ISO
IEA		 PMID:9860142
(PMID:22728827)
GO_REF:0000107		 RGD
Ensembl		 PMID:22728827 PMID:9860142 GO_REF:0000107, RGD:729588 NCBI chr 3:105,683,676...105,704,384
Ensembl chr 3:105,684,815...105,704,302 		JBrowse link
G Plcb3 phospholipase C beta 3 involved_in NAS
ISO
ISS		 PMID:8454637
(PMID:20966218), (PMID:22728827)
(PMID:20966218), (PMID:37991948)
GO_REF:0000024		 RGD
UniProt		 PMID:20966218 PMID:22728827 PMID:37991948 PMID:8454637 GO_REF:0000024, RGD:61699 NCBI chr 1:204,143,257...204,160,384
Ensembl chr 1:204,144,956...204,160,228 		JBrowse link
G Plcd1 phospholipase C, delta 1 IMP RGD PMID:16709602 RGD:2300424 NCBI chr 8:118,795,196...118,818,186
Ensembl chr 8:118,795,201...118,818,186 		JBrowse link
G Plce1 phospholipase C, epsilon 1 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:11022047), (PMID:11022048)		 Ensembl
UniProt
RGD		 PMID:11022047 PMID:11022048 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:236,243,445...236,552,571
Ensembl chr 1:236,244,683...236,551,438 		JBrowse link
G Plch2 phospholipase C, eta 2 involved_in ISO (PMID:18361507) RGD PMID:18361507 NCBI chr 5:165,544,209...165,613,769
Ensembl chr 5:165,544,200...165,602,356 		JBrowse link
G Plek pleckstrin involved_in IEA
ISO		 GO_REF:0000107
(PMID:19190246)		 Ensembl
RGD		 PMID:19190246 GO_REF:0000107 NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131 		JBrowse link
G Prkcg protein kinase C, gamma involved_in ISO (PMID:23115168) RGD PMID:23115168 NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384 		JBrowse link
G Prkd1 protein kinase D1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:67,725,193...68,039,002
Ensembl chr 6:67,725,905...68,039,042 		JBrowse link
G Prkd2 protein kinase D2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:77,513,625...77,542,386
Ensembl chr 1:77,513,986...77,542,376 		JBrowse link
G Prkd3 protein kinase D3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:16,032,507...16,108,444
Ensembl chr 6:16,032,585...16,108,443 		JBrowse link
G Ptafr platelet-activating factor receptor involved_in ISO (PMID:1657923) RGD PMID:1657923 NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251 		JBrowse link
G Ptger3 prostaglandin E receptor 3 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:7945376)		 GO_Central
RGD		 PMID:7945376 GO_REF:0000033 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
G Pth1r parathyroid hormone 1 receptor acts_upstream_of_or_within
involved_in		 IDA
ISO
IEA
IC		 MGI:3628795 (PMID:12194850)
GO_REF:0000107
PMID:19608645		 RGD
Ensembl		 PMID:12194850 PMID:9054374 PMID:19608645 GO_REF:0000107, RGD:7207455, RGD:8553376 NCBI chr 8:110,693,910...110,725,458
Ensembl chr 8:110,697,485...110,719,729 		JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in TAS PMID:8302854 UniProt PMID:8302854 RGD:68785 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975 		JBrowse link
G Rasgrp4 RAS guanyl releasing protein 4 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:22728827)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:22728827 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:84,433,033...84,452,841
Ensembl chr 1:84,433,064...84,451,896 		JBrowse link
G Rxfp3 relaxin family peptide receptor 3 acts_upstream_of_or_within ISO (PMID:16378626) RGD PMID:16378626 NCBI chr 2:60,003,256...60,004,686
Ensembl chr 2:60,003,256...60,004,686 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 IMP RGD PMID:9765227 RGD:1581785 NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681 		JBrowse link
G Sele selectin E involved_in ISO (PMID:12960351) RGD PMID:12960351 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741 		JBrowse link
G Stim1 stromal interaction molecule 1 involved_in ISO MGI:5008476 (PMID:30131394), (PMID:31664108) RGD PMID:30131394 PMID:31664108 NCBI chr 1:156,656,246...156,818,777
Ensembl chr 1:156,656,013...156,818,363 		JBrowse link
G Taar1 trace-amine-associated receptor 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:37935376), (PMID:37963465)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:37935376 PMID:37963465 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:21,517,742...21,518,740
Ensembl chr 1:21,517,258...21,532,084 		JBrowse link
G Tgm2 transglutaminase 2 involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA
IDA		 (PMID:7592956), (PMID:8943303)
GO_REF:0000033
GO_REF:0000107
PMID:7911253		 RGD
GO_Central
Ensembl		 PMID:7592956 PMID:8943303 PMID:7911253 GO_REF:0000033 GO_REF:0000107, RGD:8553754 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981 		JBrowse link
G Trhr thyrotropin releasing hormone receptor involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:75,348,672...75,393,310
Ensembl chr 7:75,348,672...75,393,309 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in IEA
ISO		 GO_REF:0000107
(PMID:18059339)		 Ensembl
RGD		 PMID:18059339 GO_REF:0000107 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Wnt5a Wnt family member 5A involved_in IEA
ISO		 GO_REF:0000107
(PMID:19099253)		 Ensembl
RGD		 PMID:19099253 GO_REF:0000107 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bicd1 BICD cargo adaptor 1 involved_in IMP
ISO		 PMID:20164183
(PMID:20164183)		 RGD PMID:20164183 PMID:20164183 RGD:8693367 NCBI chr 4:182,479,071...182,631,504
Ensembl chr 4:182,479,071...182,627,434 		JBrowse link
G Inpp5a inositol polyphosphate-5-phosphatase A involved_in ISS
ISO		 GO_REF:0000024
(PMID:26051944)		 UniProt
RGD		 PMID:26051944 GO_REF:0000024 NCBI chr 1:194,190,086...194,380,429
Ensembl chr 1:194,190,393...194,380,428 		JBrowse link
phospholipase C-activating adrenergic receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenoceptor alpha 1A involved_in IMP PMID:19011682 BHF-UCL PMID:19011682 RGD:5688340 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500 		JBrowse link
G Adra2a adrenoceptor alpha 2A involved_in ISO (PMID:10948191) RGD PMID:10948191 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
phospholipase C-activating angiotensin-activated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn2 actinin alpha 2 involved_in ISO (PMID:25433700) RGD PMID:25433700 NCBI chr17:58,143,334...58,210,622
Ensembl chr17:58,142,625...58,210,622 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a involved_in ISO (PMID:1378723) RGD PMID:1378723 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Agtr1b angiotensin II receptor, type 1b involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:102,844,969...102,920,232
Ensembl chr 2:102,844,969...102,920,232 		JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor involved_in ISO (PMID:16611642) RGD PMID:16611642 NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709 		JBrowse link
phospholipase C-activating dopamine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd1 dopamine receptor D1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:94924|MGI:95766|MGI:95776 (PMID:15016423), (PMID:17194762)
(PMID:1282671)		 Ensembl
RGD		 PMID:1282671 PMID:15016423 PMID:17194762 GO_REF:0000107 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 acts_upstream_of_or_within
involved_in		 ISO
IBA		 UniProtKB:P21728 (PMID:17194762)
MGI:95766|MGI:95776|MGI:99578 (PMID:15016423), (PMID:17194762)
GO_REF:0000033		 RGD
GO_Central		 PMID:15016423 PMID:17194762 GO_REF:0000033 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Drd4 dopamine receptor D4 involved_in IEA
ISO		 GO_REF:0000107
(PMID:1840645)		 Ensembl
RGD		 PMID:1840645 GO_REF:0000107 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Gna11 G protein subunit alpha 11 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
MGI:94924|MGI:95776|MGI:99578 (PMID:17194762)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:17194762 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:8,163,520...8,177,863
Ensembl chr 7:8,162,750...8,179,812 		JBrowse link
G Gna14 G protein subunit alpha 14 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:213,714,993...213,900,083
Ensembl chr 1:213,716,020...213,897,423 		JBrowse link
G Gna15 G protein subunit alpha 15 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:8,184,632...8,205,508
Ensembl chr 7:8,184,861...8,205,508 		JBrowse link
G Gnaq G protein subunit alpha q involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
MGI:94924|MGI:95766|MGI:99578 (PMID:17194762)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:17194762 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672 		JBrowse link
G Nherf1 NHERF family PDZ scaffold protein 1 acts_upstream_of_or_within ISO MGI:2386785 (PMID:20200151) RGD PMID:20200151 NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598 		JBrowse link
phospholipase C-activating endothelin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plcb4 phospholipase C, beta 4 involved_in ISS
ISO		 GO_REF:0000024
(PMID:35284927)		 UniProt
RGD		 PMID:35284927 GO_REF:0000024 NCBI chr 3:122,952,965...123,322,522
Ensembl chr 3:122,953,196...123,322,392 		JBrowse link
phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa7 annexin A7 acts_upstream_of_or_within_positive_effect ISO MGI:2159005 (PMID:10570150) RGD PMID:10570150 NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 involved_in ISO MGI:3770175 (PMID:16753580), (PMID:20440069) RGD PMID:16753580 PMID:20440069 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Gna11 G protein subunit alpha 11 involved_in IEA
ISO		 GO_REF:0000107
MGI:95766|MGI:95776 (PMID:20440069)		 Ensembl
RGD		 PMID:20440069 GO_REF:0000107 NCBI chr 7:8,163,520...8,177,863
Ensembl chr 7:8,162,750...8,179,812 		JBrowse link
G Gnaq G protein subunit alpha q involved_in IEA
ISO		 GO_REF:0000107
MGI:95766|MGI:95776 (PMID:20440069)		 Ensembl
RGD		 PMID:20440069 GO_REF:0000107 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 involved_in IEA
ISO		 GO_REF:0000107
MGI:88031 (PMID:10570150)		 Ensembl
RGD		 PMID:10570150 GO_REF:0000107 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491 		JBrowse link
G Plcb1 phospholipase C beta 1 involved_in IEA
ISO		 GO_REF:0000107
MGI:6460327|MGI:88031 (PMID:10570150), (PMID:31268747)		 Ensembl
RGD		 PMID:10570150 PMID:31268747 GO_REF:0000107 NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869 		JBrowse link
G Prkcb protein kinase C, beta involved_in IEA
ISO		 GO_REF:0000107
(PMID:27226533)		 Ensembl
RGD		 PMID:27226533 GO_REF:0000107 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536 		JBrowse link
G Stim1 stromal interaction molecule 1 involved_in ISO (PMID:18452988) RGD PMID:18452988 NCBI chr 1:156,656,246...156,818,777
Ensembl chr 1:156,656,013...156,818,363 		JBrowse link
phospholipase C-activating G protein-coupled glutamate receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnaq G protein subunit alpha q involved_in ISO (PMID:8253813) RGD PMID:8253813 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672 		JBrowse link
G Grm1 glutamate metabotropic receptor 1 involved_in TAS
IEA
ISO
ISS		 PMID:12514208
GO_REF:0000117
(PMID:24603153)
GO_REF:0000024		 UniProt
RGD		 PMID:24603153 PMID:12514208 GO_REF:0000024 GO_REF:0000117, RGD:728711 NCBI chr 1:5,058,285...5,453,170
Ensembl chr 1:5,058,292...5,453,170 		JBrowse link
G Grm5 glutamate metabotropic receptor 5 involved_in TAS
ISO
IEA		 (PMID:24012003)
GO_REF:0000117
PMID:12514208		 RGD
UniProt		 PMID:24012003 PMID:12189203 PMID:12514208 GO_REF:0000117, RGD:625594, RGD:728711 NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274 		JBrowse link
phospholipase C-activating serotonin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnaq G protein subunit alpha q involved_in ISO (PMID:37991948) RGD PMID:37991948 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B involved_in IEA
ISO		 GO_REF:0000107
(PMID:17325130)		 Ensembl
RGD		 PMID:17325130 GO_REF:0000107 NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A involved_in IDA
ISO
IBA		 (PMID:35084960)
GO_REF:0000033		 RGD
GO_Central		 PMID:35084960 PMID:17010161 GO_REF:0000033, RGD:1624387 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B involved_in IEA
ISO
ISS
IBA		 GO_REF:0000107
(PMID:17325130)
(PMID:12970106), (PMID:20099302), (PMID:30127358), (PMID:36087581)
GO_REF:0000024
GO_REF:0000033		 Ensembl
RGD
UniProt
GO_Central		 PMID:12970106 PMID:17325130 PMID:20099302 PMID:30127358 PMID:36087581 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:86,735,793...86,756,638
Ensembl chr 9:86,742,102...86,755,108 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C involved_in IDA
ISO
IBA		 (PMID:21835345)
(PMID:12970106), (PMID:29398112)
GO_REF:0000033		 RGD
GO_Central		 PMID:12970106 PMID:21835345 PMID:29398112 PMID:12435801 GO_REF:0000033, RGD:1598460 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Plcb3 phospholipase C beta 3 involved_in IEA
ISO		 GO_REF:0000107
(PMID:20966218)		 Ensembl
RGD		 PMID:20966218 GO_REF:0000107 NCBI chr 1:204,143,257...204,160,384
Ensembl chr 1:204,144,956...204,160,228 		JBrowse link
positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chga chromogranin A IDA RGD PMID:11257446 RGD:6907050 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398 		JBrowse link
G F2 coagulation factor II, thrombin involved_in IEA
ISO		 GO_REF:0000107
(PMID:20164183)		 Ensembl
RGD		 PMID:20164183 GO_REF:0000107 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G Gpr27 G protein-coupled receptor 27 acts_upstream_of_or_within ISO (PMID:22253604) RGD PMID:22253604 NCBI chr 4:132,328,364...132,329,497
Ensembl chr 4:132,328,364...132,329,497 		JBrowse link
G Grp gastrin releasing peptide involved_in ISS
ISO		 GO_REF:0000024
(PMID:26658875)		 UniProt
RGD		 PMID:26658875 GO_REF:0000024 NCBI chr18:59,388,679...59,402,061
Ensembl chr18:59,388,274...59,402,061 		JBrowse link
G Nrxn1 neurexin 1 involved_in ISO (PMID:26078884) RGD PMID:26078884 NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      signal transduction 7183
        G protein-coupled receptor signaling pathway 2447
          phospholipase C-activating G protein-coupled receptor signaling pathway 137
            negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway + 2
            phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway 8
            phospholipase C-activating G protein-coupled glutamate receptor signaling pathway 3
            phospholipase C-activating adrenergic receptor signaling pathway 2
            phospholipase C-activating angiotensin-activated signaling pathway + 4
            phospholipase C-activating dopamine receptor signaling pathway + 9
            phospholipase C-activating endothelin receptor signaling pathway 1
            phospholipase C-activating opsin-mediated signaling pathway + 0
            phospholipase C-activating serotonin receptor signaling pathway 6
            phospholipase C-activating tachykinin receptor signaling pathway 0
            positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway 5
            regulation of phospholipase C-activating G protein-coupled receptor signaling pathway + 7
Path 2
Term Annotations click to browse term
  biological_process 20076
    biological regulation 13559
      regulation of biological process 13136
        signaling 7744
          signal transduction 7183
            G protein-coupled receptor signaling pathway 2447
              phospholipase C-activating G protein-coupled receptor signaling pathway 137
                negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway + 2
                phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway 8
                phospholipase C-activating G protein-coupled glutamate receptor signaling pathway 3
                phospholipase C-activating adrenergic receptor signaling pathway 2
                phospholipase C-activating angiotensin-activated signaling pathway + 4
                phospholipase C-activating dopamine receptor signaling pathway + 9
                phospholipase C-activating endothelin receptor signaling pathway 1
                phospholipase C-activating opsin-mediated signaling pathway + 0
                phospholipase C-activating serotonin receptor signaling pathway 6
                phospholipase C-activating tachykinin receptor signaling pathway 0
                positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway 5
                regulation of phospholipase C-activating G protein-coupled receptor signaling pathway + 7
paths to the root