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ONTOLOGY REPORT - ANNOTATIONS

Term:G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
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Accession:GO:0007187 term browser browse the term
Definition:A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation or inhibition of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide.
Synonyms:exact_synonym: G protein signaling, coupled to cyclic nucleotide second messenger;   G protein signalling, coupled to cyclic nucleotide second messenger;   GPCR signaling pathway via cyclic nucleotide second messenger


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G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07071765.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Anxa1 annexin A1 involved_in ISO
IEA
ISS		 (PMID:15187149), (PMID:25664854)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:15187149 PMID:25664854 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159 		JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:99,284,846...99,337,252
Ensembl chr 3:99,284,846...99,337,252 		JBrowse link
G Drd1 dopamine receptor D1 involved_in ISO
IBA		 (PMID:1282671)
GO_REF:0000033		 RGD
GO_Central		 PMID:1282671 GO_REF:0000033 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd4 dopamine receptor D4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Galr3 galanin receptor 3 involved_in ISO
IEA		 (PMID:9832121)
GO_REF:0000107		 RGD
Ensembl		 PMID:9832121 GO_REF:0000107 NCBI chr 7:110,603,525...110,608,429
Ensembl chr 7:110,605,226...110,607,685 		JBrowse link
G Hrh1 histamine receptor H 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:147,564,963...147,649,353
Ensembl chr 4:147,645,995...147,647,455 		JBrowse link
G Hrh2 histamine receptor H 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:10,366,004...10,407,791
Ensembl chr17:10,368,298...10,407,631 		JBrowse link
G Hrh3 histamine receptor H3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642 		JBrowse link
G Hrh4 histamine receptor H4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:4,166,270...4,182,426
Ensembl chr18:4,166,270...4,246,345 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Htr1d 5-hydroxytryptamine receptor 1D involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:148,656,252...148,676,532
Ensembl chr 5:148,674,495...148,675,619 		JBrowse link
G Htr1f 5-hydroxytryptamine receptor 1F involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:2,642,751...2,644,150
Ensembl chr11:2,642,751...2,644,150 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:86,735,793...86,756,638
Ensembl chr 9:86,742,102...86,755,108 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C involved_in TAS
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:9153397 GO_REF:0000033, RGD:1358735 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Htr4 5-hydroxytryptamine receptor 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:55,765,981...55,949,921
Ensembl chr18:55,766,725...55,949,321 		JBrowse link
G Htr5a 5-hydroxytryptamine receptor 5A involved_in IMP
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:10861802 GO_REF:0000033, RGD:2316997 NCBI chr 4:7,444,968...7,454,651
Ensembl chr 4:7,444,968...7,454,651 		JBrowse link
G Htr5b 5-hydroxytryptamine (serotonin) receptor 5B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:32,686,911...32,699,835
Ensembl chr13:32,687,042...32,699,835 		JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 involved_in IMP
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:7680751 GO_REF:0000033, RGD:729174 NCBI chr 5:151,295,269...151,312,853
Ensembl chr 5:151,296,662...151,311,912 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 involved_in TAS
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:8397408 GO_REF:0000033, RGD:70768 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626 		JBrowse link
G Or10j5 olfactory receptor family 10 subfamily J member 5 involved_in ISO (PMID:28842679) RGD PMID:28842679 NCBI chr13:85,430,655...85,431,584
Ensembl chr13:85,424,254...85,432,107 		JBrowse link
G Pth1r parathyroid hormone 1 receptor IMP RGD PMID:8662729 RGD:7207456 NCBI chr 8:110,693,910...110,725,458
Ensembl chr 8:110,697,485...110,719,729 		JBrowse link
G Vipr1 vasoactive intestinal peptide receptor 1 involved_in ISO
IEA		 (PMID:8390245)
GO_REF:0000107		 RGD
Ensembl		 PMID:8390245 GO_REF:0000107 NCBI chr 8:121,303,739...121,339,587
Ensembl chr 8:121,310,248...121,339,585 		JBrowse link
G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr2 angiotensin II receptor, type 2 involved_in ISO (PMID:17000928) RGD PMID:17000928 NCBI chr  X:112,119,876...112,124,060
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
G Fzd2 frizzled class receptor 2 IDA RGD PMID:12471263 RGD:727481 NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334 		JBrowse link
G Gpr3 G protein-coupled receptor 3 involved_in ISO (PMID:22685609) RGD PMID:22685609 NCBI chr 5:145,411,500...145,414,621
Ensembl chr 5:145,411,510...145,414,590 		JBrowse link
G Hrh1 histamine receptor H 1 TAS RGD PMID:12419527 RGD:727463 NCBI chr 4:147,564,963...147,649,353
Ensembl chr 4:147,645,995...147,647,455 		JBrowse link
G Nos2 nitric oxide synthase 2 IDA RGD PMID:12107056 RGD:625635 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      signal transduction 7183
        G protein-coupled receptor signaling pathway 2447
          G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger 33
            G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger 5
Path 2
Term Annotations click to browse term
  biological_process 20076
    biological regulation 13559
      regulation of biological process 13136
        signaling 7744
          signal transduction 7183
            G protein-coupled receptor signaling pathway 2447
              G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger 33
                G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger 5
paths to the root