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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:synaptonemal complex assembly
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Accession:GO:0007130 term browser browse the term
Definition:The cell cycle process in which the synaptonemal complex is formed. This is a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination.
Synonyms:exact_synonym: synaptonemal complex formation



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synaptonemal complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ago4 argonaute RISC component 4 acts_upstream_of_or_within IEA
ISO
GO_REF:0000107
MGI:5438526 (PMID:22863743)
Ensembl
RGD
PMID:22863743 GO_REF:0000107 NCBI chr 5:144,064,949...144,110,422
Ensembl chr 5:144,064,949...144,110,402
JBrowse link
G Bag6 BAG cochaperone 6 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:18678708)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:18678708 GO_REF:0000024 GO_REF:0000107 NCBI chr20:3,680,607...3,693,329
Ensembl chr20:3,680,607...3,693,329
JBrowse link
G C14h1orf146 similar to human chromosome 1 open reading frame 146 involved_in ISO (PMID:30949703) RGD PMID:30949703 NCBI chr14:2,375,311...2,395,331
Ensembl chr14:2,374,948...2,386,112
JBrowse link
G Cpeb1 cytoplasmic polyadenylation element binding protein 1 acts_upstream_of_or_within ISO (PMID:12815066)
MGI:3606747 (PMID:11702780)
RGD PMID:11702780 PMID:12815066 NCBI chr 1:144,709,278...144,817,388
Ensembl chr 1:144,709,691...144,815,880
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 acts_upstream_of_or_within ISO MGI:3718790 (PMID:17599069) RGD PMID:17599069 NCBI chr20:3,924,263...3,941,238
Ensembl chr20:3,924,263...3,941,384
JBrowse link
G Hormad1 HORMA domain containing 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:21478856)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:21478856 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:185,803,572...185,841,449
Ensembl chr 2:185,805,669...185,841,249
JBrowse link
G Mcmdc2 minichromosome maintenance domain containing 2 acts_upstream_of_or_within ISO MGI:2178050|MGI:5511194 (PMID:27760146) RGD PMID:27760146 NCBI chr 5:14,071,609...14,120,435
Ensembl chr 5:14,080,968...14,120,351
JBrowse link
G Meioc meiosis specific with coiled-coil domain involved_in IEA
ISO
GO_REF:0000107
(PMID:26742488)
Ensembl
RGD
PMID:26742488 GO_REF:0000107 NCBI chr10:88,128,939...88,147,833
Ensembl chr10:88,128,990...88,147,829
JBrowse link
G Mlh3 mutL homolog 3 acts_upstream_of_or_within IEA
ISO
GO_REF:0000107
MGI:2384218 (PMID:16260499)
Ensembl
RGD
PMID:16260499 GO_REF:0000107 NCBI chr 6:110,612,535...110,649,408
Ensembl chr 6:110,612,535...110,648,999
JBrowse link
G Rad21l1 RAD21 cohesin complex component like 1 acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 3:160,620,500...160,648,716
Ensembl chr 3:160,620,564...160,648,909
JBrowse link
G Rec8 REC8 meiotic recombination protein acts_upstream_of_or_within IEA
ISO
GO_REF:0000107
MGI:1349669|MGI:3652039 (PMID:22711701), (PMID:24589552)
Ensembl
RGD
PMID:22711701 PMID:24589552 GO_REF:0000107 NCBI chr15:33,079,818...33,087,283
Ensembl chr15:33,079,801...33,087,282
JBrowse link
G Shoc1 shortage in chiasmata 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:35485979)
Ensembl
RGD
PMID:35485979 GO_REF:0000107 NCBI chr 5:78,655,723...78,751,658
Ensembl chr 5:78,660,662...78,751,709
JBrowse link
G Six6os1 Six6 opposite strand transcript 1 involved_in ISO (PMID:33508233) RGD PMID:33508233 NCBI chr 6:97,314,829...97,351,069
Ensembl chr 6:97,314,712...97,351,171
JBrowse link
G Spo11 SPO11 initiator of meiotic double strand breaks acts_upstream_of_or_within IEA
ISO
GO_REF:0000107
MGI:1929645|MGI:2178805|MGI:3652039 (PMID:24589552), (PMID:27760146)
Ensembl
RGD
PMID:24589552 PMID:27760146 GO_REF:0000107 NCBI chr 3:182,173,615...182,189,273
Ensembl chr 3:182,175,861...182,189,276
JBrowse link
G Syce1 synaptonemal complex central element protein 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:205,281,808...205,292,811
Ensembl chr 1:205,218,653...205,322,623
JBrowse link
G Syce1l synaptonemal complex central element protein 1-like involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr19:58,534,205...58,544,651
Ensembl chr19:58,534,113...58,544,653
JBrowse link
G Syce3 synaptonemal complex central element protein 3 involved_in IBA
ISO
IEA
GO_REF:0000033
(PMID:21637789)
GO_REF:0000107
GO_REF:0000002
GO_Central
RGD
Ensembl
InterPro
PMID:21637789 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:122,336,427...122,362,608
Ensembl chr 7:122,336,427...122,344,820
JBrowse link
G Sycp1 synaptonemal complex protein 1 involved_in
acts_upstream_of_or_within
ISS
ISO
IEA
GO_REF:0000024
MGI:105931|MGI:109542|MGI:3580000 (PMID:22164254)
(PMID:15937223), (PMID:15944401)
GO_REF:0000002
UniProt
RGD
InterPro
PMID:15937223 PMID:15944401 PMID:22164254 GO_REF:0000002 GO_REF:0000024 NCBI chr 2:192,985,164...193,145,234
Ensembl chr 2:192,984,621...193,145,421
JBrowse link
G Sycp3 synaptonemal complex protein 3 acts_upstream_of_or_within
involved_in
ISO MGI:1913904 (PMID:22164254)
(PMID:10678170)
RGD PMID:10678170 PMID:22164254 NCBI chr 7:24,761,476...24,775,933
Ensembl chr 7:24,761,463...24,776,501
JBrowse link
G Syde1 synapse defective Rho GTPase homolog 1 acts_upstream_of_or_within ISO (PMID:23791195) RGD PMID:23791195 NCBI chr 7:11,683,505...11,689,491
Ensembl chr 7:11,681,111...11,690,443
JBrowse link
G Terb2 telomere repeat binding bouquet formation protein 2 acts_upstream_of_or_within IEA
ISO
GO_REF:0000107
MGI:6362934|MGI:6362936 (PMID:30718482)
Ensembl
RGD
PMID:30718482 GO_REF:0000107 NCBI chr 3:129,591,933...129,610,293
Ensembl chr 3:129,591,940...129,610,290
JBrowse link
G Tex11 testis expressed 11 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:3526163 (PMID:18316482)
GO_Central
RGD
PMID:18316482 GO_REF:0000033 NCBI chr  X:69,973,012...70,236,544
Ensembl chr  X:69,972,723...70,236,011
JBrowse link
G Tex12 testis expressed 12 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:109542|MGI:3811722 (PMID:22164254)
GO_Central
RGD
PMID:22164254 GO_REF:0000033 NCBI chr 8:59,804,662...59,809,595
Ensembl chr 8:59,804,662...59,813,423
JBrowse link
G Tex15 testis expressed 15, meiosis and synapsis associated involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:3526165 (PMID:18283110)
GO_Central
RGD
PMID:18283110 GO_REF:0000033 NCBI chr16:65,302,049...65,362,065
Ensembl chr16:65,302,049...65,361,462
JBrowse link
G Trip13 thyroid hormone receptor interactor 13 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:20711356)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:20711356 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:31,185,700...31,230,638
Ensembl chr 1:31,185,594...31,230,634
JBrowse link
lateral element assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sycp1 synaptonemal complex protein 1 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:109542 (PMID:22164254)
GO_Central
RGD
PMID:22164254 GO_REF:0000033 NCBI chr 2:192,985,164...193,145,234
Ensembl chr 2:192,984,621...193,145,421
JBrowse link
G Sycp3 synaptonemal complex protein 3 acts_upstream_of_or_within ISO MGI:105931 (PMID:22164254) RGD PMID:22164254 NCBI chr 7:24,761,476...24,775,933
Ensembl chr 7:24,761,463...24,776,501
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    reproductive process 1998
      meiotic cell cycle process 252
        chromosome organization involved in meiotic cell cycle 74
          synaptonemal complex assembly 25
            lateral element assembly 2
            positive regulation of synaptonemal complex assembly 0
            regulation of synaptonemal complex assembly + 0
Path 2
Term Annotations click to browse term
  biological_process 19315
    cellular process 18484
      cellular component organization or biogenesis 7050
        cellular component organization 6802
          organelle organization 3674
            organelle fission 523
              nuclear division 461
                meiotic nuclear division 220
                  meiosis I 137
                    homologous chromosome segregation 74
                      homologous chromosome pairing at meiosis 58
                        synaptonemal complex assembly 25
                          lateral element assembly 2
                          positive regulation of synaptonemal complex assembly 0
                          regulation of synaptonemal complex assembly + 0
paths to the root