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ONTOLOGY REPORT - ANNOTATIONS

Term:mitotic sister chromatid cohesion
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Accession:GO:0007064 term browser browse the term
Definition:The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission.


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mitotic sister chromatid cohesion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07057438.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 7:63,949,734...63,951,518 JBrowse link
G Cdc20 cell division cycle 20 acts_upstream_of_or_within ISO
IEA 		MGI:1353578 (PMID:17325031)
GO_REF:0000107 		RGD
Ensembl		 PMID:17325031 GO_REF:0000107 NCBI chr 5:137,251,596...137,255,799
Ensembl chr 5:131,966,215...131,970,512 		JBrowse link
G Cdca5 cell division cycle associated 5 involved_in ISO
IBA 		UniProtKB:Q96FF9 (PMID:21111234)
UniProtKB:Q29RF7 (PMID:15837422), (PMID:17349791), (PMID:21111234)
GO_REF:0000033 		RGD
GO_Central		 PMID:15837422 PMID:17349791 PMID:21111234 GO_REF:0000033 NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023 		JBrowse link
G Chtf8 chromosome transmission fidelity factor 8 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr19:34,782,005...34,792,306
Ensembl chr19:34,781,856...34,792,578 		JBrowse link
G Dscc1 DNA replication and sister chromatid cohesion 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:86,482,588...86,498,212
Ensembl chr 7:86,482,588...86,498,212 		JBrowse link
G Esco1 establishment of sister chromatid cohesion N-acetyltransferase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:1,904,748...1,959,609
Ensembl chr18:1,631,954...1,686,942 		JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:44,210,124...44,230,785
Ensembl chr15:40,034,568...40,055,306
Ensembl chr15:40,034,568...40,055,306 		JBrowse link
G Haspin histone H3 associated protein kinase involved_in ISO
IEA 		(PMID:20705812)
GO_REF:0000107 		RGD
Ensembl		 PMID:20705812 GO_REF:0000107 NCBI chr10:57,747,731...57,750,518
Ensembl chr10:57,747,573...57,750,512 		JBrowse link
G Hdac8 histone deacetylase 8 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:22885700) 		UniProt
Ensembl
RGD		 PMID:22885700 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:67,385,288...67,593,014
Ensembl chr  X:67,385,289...67,592,923 		JBrowse link
G Mau2 MAU2 sister chromatid cohesion factor involved_in ISO
IEA 		(PMID:22628566)
GO_REF:0000107
GO_REF:0000002 		RGD
Ensembl
InterPro		 PMID:22628566 GO_REF:0000002 GO_REF:0000107 NCBI chr16:19,383,847...19,414,996
Ensembl chr16:19,383,492...19,408,727 		JBrowse link
G Naa50 N(alpha)-acetyltransferase 50, NatE catalytic subunit involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:70,044,281...70,066,754
Ensembl chr11:56,538,366...56,560,842 		JBrowse link
G Nipbl NIPBL, cohesin loading factor involved_in ISO
IEA 		(PMID:16100726), (PMID:22628566)
GO_REF:0000107 		RGD
Ensembl		 PMID:16100726 PMID:22628566 GO_REF:0000107 NCBI chr 2:57,399,443...57,586,770
Ensembl chr 2:57,399,445...57,565,899 		JBrowse link
G Pds5a PDS5 cohesin associated factor A involved_in ISO
IEA
IBA 		UniProtKB:Q96FF9 (PMID:21111234)
GO_REF:0000002
GO_REF:0000033 		RGD
InterPro
GO_Central		 PMID:21111234 GO_REF:0000002 GO_REF:0000033 NCBI chr14:42,551,653...42,651,074
Ensembl chr14:42,552,647...42,648,669 		JBrowse link
G Pds5b PDS5 cohesin associated factor B involved_in IEA
IBA
ISS
ISO 		GO_REF:0000002
GO_REF:0000033
GO_REF:0000024
(PMID:15855230)
GO_REF:0000107 		InterPro
GO_Central
UniProt
RGD
Ensembl		 PMID:15855230 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr12:202,481...345,596
Ensembl chr12:255,313...345,596 		JBrowse link
G Pogz pogo transposable element derived with ZNF domain involved_in ISO (PMID:20562864) RGD PMID:20562864 NCBI chr 2:182,394,269...182,440,711
Ensembl chr 2:182,380,768...182,440,707 		JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin acts_upstream_of_or_within ISO
IEA 		MGI:1859866 (PMID:17325031)
GO_REF:0000107 		RGD
Ensembl		 PMID:17325031 GO_REF:0000107 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837 		JBrowse link
G Smc3 structural maintenance of chromosomes 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:252,601,422...252,644,522
Ensembl chr 1:252,601,753...252,644,522 		JBrowse link
establishment of mitotic sister chromatid cohesion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Naa50 N(alpha)-acetyltransferase 50, NatE catalytic subunit involved_in ISO
IEA 		(PMID:27422821)
GO_REF:0000107 		RGD
Ensembl		 PMID:27422821 GO_REF:0000107 NCBI chr11:70,044,281...70,066,754
Ensembl chr11:56,538,366...56,560,842 		JBrowse link
G Nipbl NIPBL, cohesin loading factor involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:57,399,443...57,586,770
Ensembl chr 2:57,399,445...57,565,899 		JBrowse link
maintenance of mitotic sister chromatid cohesion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dscc1 DNA replication and sister chromatid cohesion 1 involved_in ISO
IBA 		(PMID:16682347), (PMID:19907496)
GO_REF:0000033 		RGD
GO_Central		 PMID:16682347 PMID:19907496 GO_REF:0000033 NCBI chr 7:86,482,588...86,498,212
Ensembl chr 7:86,482,588...86,498,212 		JBrowse link
G Mau2 MAU2 sister chromatid cohesion factor involved_in ISO
IEA
IBA 		(PMID:16682347), (PMID:16802858)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:16682347 PMID:16802858 GO_REF:0000033 GO_REF:0000107 NCBI chr16:19,383,847...19,414,996
Ensembl chr16:19,383,492...19,408,727 		JBrowse link
G Nipbl NIPBL, cohesin loading factor involved_in ISO
IEA 		(PMID:16682347)
GO_REF:0000107 		RGD
Ensembl		 PMID:16682347 GO_REF:0000107 NCBI chr 2:57,399,443...57,586,770
Ensembl chr 2:57,399,445...57,565,899 		JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in ISO
IEA 		(PMID:20551165)
GO_REF:0000107 		RGD
Ensembl		 PMID:20551165 GO_REF:0000107 NCBI chr15:54,780,858...54,911,989
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
mitotic sister chromatid cohesion, centromeric term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bod1 biorientation of chromosomes in cell division 1 involved_in ISO (PMID:24157919) RGD PMID:24157919 NCBI chr10:15,993,454...15,999,795
Ensembl chr10:15,993,454...15,999,787 		JBrowse link
G Naa50 N(alpha)-acetyltransferase 50, NatE catalytic subunit involved_in ISO
IEA 		(PMID:17502424)
GO_REF:0000107 		RGD
Ensembl		 PMID:17502424 GO_REF:0000107 NCBI chr11:70,044,281...70,066,754
Ensembl chr11:56,538,366...56,560,842 		JBrowse link
G Sgo1 shugoshin 1 involved_in ISO (PMID:24157919) RGD PMID:24157919 NCBI chr 9:6,672,109...6,687,908
Ensembl chr 9:6,672,123...6,687,805 		JBrowse link
negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Naa10 N(alpha)-acetyltransferase 10, NatA catalytic subunit involved_in ISO
IEA 		(PMID:27422821)
GO_REF:0000107 		RGD
Ensembl		 PMID:27422821 GO_REF:0000107 NCBI chr  X:156,807,378...156,812,632
Ensembl chr  X:151,656,056...151,661,252 		JBrowse link
negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atrx ATRX, chromatin remodeler involved_in ISO
IEA 		(PMID:26373281)
GO_REF:0000107 		RGD
Ensembl		 PMID:26373281 GO_REF:0000107 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330 		JBrowse link
G Tnks tankyrase involved_in ISO (PMID:26373281) RGD PMID:26373281 NCBI chr16:57,223,174...57,370,740
Ensembl chr16:57,225,094...57,366,260 		JBrowse link
positive regulation of maintenance of mitotic sister chromatid cohesion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Macroh2a1 macroH2A.1 histone involved_in ISO
IEA 		(PMID:26373281)
GO_REF:0000107 		RGD
Ensembl		 PMID:26373281 GO_REF:0000107 NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072 		JBrowse link
G Nsmce2 NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase involved_in ISO
IEA
ISS 		(PMID:19502785)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:19502785 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:92,825,568...93,071,037
Ensembl chr 7:90,936,112...91,164,899 		JBrowse link
G Slf1 SMC5-SMC6 complex localization factor 1 involved_in ISO (PMID:25931565) RGD PMID:25931565 NCBI chr 2:6,767,015...6,874,428
Ensembl chr 2:6,767,015...6,867,149 		JBrowse link
G Slf2 SMC5-SMC6 complex localization factor 2 involved_in ISO
IEA 		(PMID:25931565)
GO_REF:0000107 		RGD
Ensembl		 PMID:25931565 GO_REF:0000107 NCBI chr 1:243,782,786...243,845,418
Ensembl chr 1:243,782,246...243,845,250 		JBrowse link
G Smc5 structural maintenance of chromosomes 5 involved_in ISO (PMID:19502785) RGD PMID:19502785 NCBI chr 1:220,769,366...220,839,138
Ensembl chr 1:220,769,366...220,839,096 		JBrowse link
positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase involved_in ISO
IEA 		(PMID:25308863)
GO_REF:0000107 		RGD
Ensembl		 PMID:25308863 GO_REF:0000107 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      cell cycle process 1324
        sister chromatid cohesion 61
          mitotic sister chromatid cohesion 29
            establishment of mitotic sister chromatid cohesion 2
            maintenance of mitotic sister chromatid cohesion + 13
            mitotic sister chromatid cohesion, arms + 0
            mitotic sister chromatid cohesion, centromeric + 5
            mitotic sister chromatid cohesion, telomeric + 2
Path 2
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      cellular component organization or biogenesis 7114
        cellular component organization 6827
          organelle organization 3713
            chromosome organization 530
              sister chromatid cohesion 61
                mitotic sister chromatid cohesion 29
                  establishment of mitotic sister chromatid cohesion 2
                  maintenance of mitotic sister chromatid cohesion + 13
                  mitotic sister chromatid cohesion, arms + 0
                  mitotic sister chromatid cohesion, centromeric + 5
                  mitotic sister chromatid cohesion, telomeric + 2
paths to the root