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ONTOLOGY REPORT - ANNOTATIONS

Term:lysosomal lumen acidification
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Accession:GO:0007042 term browser browse the term
Definition:Any process that reduces the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.
Synonyms:exact_synonym: lysosome pH reduction


show annotations for term's descendants           Sort by:
lysosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap2 ATPase H+ transporting accessory protein 2 involved_in ISO
ISS		 (PMID:32276428)
GO_REF:0000024		 RGD
UniProt		 PMID:32276428 GO_REF:0000024 NCBI chr  X:12,856,708...12,883,670
Ensembl chr  X:10,183,068...10,210,918 		JBrowse link
G Ccdc115 coiled-coil domain containing 115 involved_in ISO (PMID:28296633) RGD PMID:28296633 NCBI chr 9:36,650,384...36,654,348
Ensembl chr 9:36,649,271...36,653,946 		JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO
IBA		 (PMID:11722572)
GO_REF:0000033		 RGD
GO_Central		 PMID:11722572 GO_REF:0000033 NCBI chr 1:190,586,649...190,600,034
Ensembl chr 1:181,156,073...181,167,434 		JBrowse link
G Cln5 CLN5, intracellular trafficking protein involved_in ISO (PMID:11722572) RGD PMID:11722572 NCBI chr15:86,308,286...86,321,679
Ensembl chr15:79,893,548...79,903,438
Ensembl chr 2:79,893,548...79,903,438 		JBrowse link
G Cln6 CLN6, transmembrane ER protein involved_in ISO
IEA		 (PMID:11722572)
GO_REF:0000107		 RGD
Ensembl		 PMID:11722572 GO_REF:0000107 NCBI chr 8:63,303,356...63,318,360
Ensembl chr 8:63,303,029...63,318,360 		JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 acts_upstream_of_or_within ISO (PMID:33966596) RGD PMID:33966596 NCBI chr13:80,552,779...80,565,272
Ensembl chr13:78,019,843...78,032,308 		JBrowse link
G Grn granulin precursor involved_in ISS
ISO		 GO_REF:0000024
(PMID:28073925)		 UniProt
RGD		 PMID:28073925 GO_REF:0000024 NCBI chr10:87,887,834...87,893,938
Ensembl chr10:87,387,638...87,393,775 		JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:37390818)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:37390818 GO_REF:0000024 GO_REF:0000107 NCBI chr16:83,058,131...83,082,843
Ensembl chr16:76,355,984...76,381,883 		JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:37390818)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:37390818 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:122,038,734...122,087,745
Ensembl chr  X:117,057,606...117,260,522 		JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 involved_in ISO
IEA
ISS		 (PMID:11722572)
GO_REF:0000107
PMID:8895569		 RGD
Ensembl		 PMID:11722572 PMID:8895569 GO_REF:0000107, RGD:8553248 NCBI chr 5:140,406,318...140,427,201
Ensembl chr 5:135,121,163...135,142,048 		JBrowse link
G Snapin SNAP-associated protein acts_upstream_of_or_within ISO MGI:3608768 (PMID:20920792) RGD PMID:20920792 NCBI chr 2:178,269,157...178,271,746
Ensembl chr 2:175,971,257...175,974,231 		JBrowse link
G Tmem106b transmembrane protein 106B acts_upstream_of_or_within ISO MGI:5319917 (PMID:28728022) RGD PMID:28728022 NCBI chr 4:41,328,125...41,347,315
Ensembl chr 4:41,327,994...41,345,619 		JBrowse link
G Tmem199 transmembrane protein 199 involved_in ISO
ISS
IEA		 (PMID:28296633)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:28296633 GO_REF:0000024 GO_REF:0000107 NCBI chr10:63,402,493...63,407,065
Ensembl chr10:63,402,494...63,407,108 		JBrowse link
G Tmem9 transmembrane protein 9 involved_in ISO
IEA		 (PMID:30374053)
GO_REF:0000107		 RGD
Ensembl		 PMID:30374053 GO_REF:0000107 NCBI chr13:47,458,486...47,475,832
Ensembl chr13:47,458,498...47,475,832 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    biological regulation 13833
      regulation of biological quality 3462
        regulation of intracellular pH 83
          regulation of lysosomal lumen pH 22
            lysosomal lumen acidification 14
Path 2
Term Annotations click to browse term
  biological_process 20558
    homeostatic process 2020
      chemical homeostasis 1234
        monoatomic ion homeostasis 684
          monoatomic cation homeostasis 670
            regulation of pH 107
              regulation of cellular pH 92
                regulation of intracellular pH 83
                  intracellular pH reduction 47
                    vacuolar acidification 25
                      lysosomal lumen acidification 14
paths to the root