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ONTOLOGY REPORT - ANNOTATIONS

Term:vacuolar acidification
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Accession:GO:0007035 term browser browse the term
Definition:Any process that reduces the pH of the vacuole, measured by the concentration of the hydrogen ion.


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vacuolar acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6v0a1 ATPase H+ transporting V0 subunit a1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:86,436,089...86,490,185
Ensembl chr10:85,935,854...85,989,895 		JBrowse link
G Atp6v0a4 ATPase H+ transporting V0 subunit a4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:67,727,145...67,809,092
Ensembl chr 4:66,760,159...66,842,110 		JBrowse link
G Atp6v0d1 ATPase H+ transporting V0 subunit D1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:50,313,268...50,357,248
Ensembl chr19:33,403,355...33,447,450 		JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:38,133,151...38,182,245
Ensembl chr 5:33,336,264...33,385,354 		JBrowse link
G Atp6v1b1 ATPase H+ transporting V1 subunit B1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:117,781,444...117,800,103
Ensembl chr 4:116,223,799...116,242,475 		JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 involved_in TAS
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:15013950 GO_REF:0000033, RGD:1304309 NCBI chr16:25,384,254...25,408,388
Ensembl chr16:20,617,518...20,641,745 		JBrowse link
G Clic4 chloride intracellular channel 4 acts_upstream_of_or_within ISO
IEA		 MGI:3838012 (PMID:19197003)
GO_REF:0000107		 RGD
Ensembl		 PMID:19197003 GO_REF:0000107 NCBI chr 5:147,453,702...147,513,455
Ensembl chr 5:147,453,712...147,513,452 		JBrowse link
G Dmxl1 Dmx-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:45,179,505...45,349,999
Ensembl chr18:42,993,340...43,163,456 		JBrowse link
G Dmxl2 Dmx-like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:63,637,314...63,803,911
Ensembl chr 8:54,741,160...54,885,161 		JBrowse link
G Slc11a1 solute carrier family 11 member 1 acts_upstream_of_or_within ISO
IEA		 MGI:2446573 (PMID:11067873), (PMID:18984740), (PMID:9670047)
GO_REF:0000107		 RGD
Ensembl		 PMID:9670047 PMID:11067873 PMID:18984740 GO_REF:0000107 NCBI chr 9:83,406,327...83,417,252
Ensembl chr 9:75,957,316...75,968,101 		JBrowse link
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:210,556,270...210,568,021
Ensembl chr 1:201,127,034...201,138,742 		JBrowse link
lysosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap2 ATPase H+ transporting accessory protein 2 involved_in ISO
ISS		 (PMID:32276428)
GO_REF:0000024		 RGD
UniProt		 PMID:32276428 GO_REF:0000024 NCBI chr  X:12,856,708...12,883,670
Ensembl chr  X:10,183,068...10,210,918 		JBrowse link
G Ccdc115 coiled-coil domain containing 115 involved_in ISO (PMID:28296633) RGD PMID:28296633 NCBI chr 9:36,650,384...36,654,348
Ensembl chr 9:36,649,271...36,653,946 		JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO
IBA		 (PMID:11722572)
GO_REF:0000033		 RGD
GO_Central		 PMID:11722572 GO_REF:0000033 NCBI chr 1:190,586,649...190,600,034
Ensembl chr 1:181,156,073...181,167,434 		JBrowse link
G Cln5 CLN5, intracellular trafficking protein involved_in ISO (PMID:11722572) RGD PMID:11722572 NCBI chr15:86,308,286...86,321,679
Ensembl chr15:79,893,548...79,903,438
Ensembl chr 2:79,893,548...79,903,438 		JBrowse link
G Cln6 CLN6, transmembrane ER protein involved_in ISO
IEA		 (PMID:11722572)
GO_REF:0000107		 RGD
Ensembl		 PMID:11722572 GO_REF:0000107 NCBI chr 8:72,198,773...72,213,777
Ensembl chr 8:63,303,029...63,318,360 		JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 acts_upstream_of_or_within ISO (PMID:33966596) RGD PMID:33966596 NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308 		JBrowse link
G Grn granulin precursor involved_in ISS
ISO		 GO_REF:0000024
(PMID:28073925)		 UniProt
RGD		 PMID:28073925 GO_REF:0000024 NCBI chr10:87,887,834...87,893,938
Ensembl chr10:87,387,638...87,393,775 		JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:37390818)		 Ensembl
UniProt
RGD		 PMID:37390818 GO_REF:0000024 GO_REF:0000107 NCBI chr16:83,058,131...83,082,843
Ensembl chr16:76,355,984...76,381,883 		JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:37390818)		 Ensembl
UniProt
RGD		 PMID:37390818 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:122,038,734...122,087,745
Ensembl chr  X:117,057,606...117,260,522 		JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 involved_in ISO
ISS
IEA		 (PMID:11722572)
PMID:8895569
GO_REF:0000107		 RGD
Ensembl		 PMID:11722572 PMID:8895569 GO_REF:0000107, RGD:8553248 NCBI chr 5:140,406,318...140,427,201
Ensembl chr 5:135,121,163...135,142,048 		JBrowse link
G Snapin SNAP-associated protein acts_upstream_of_or_within ISO MGI:3608768 (PMID:20920792) RGD PMID:20920792 NCBI chr 2:178,269,157...178,271,746
Ensembl chr 2:175,971,257...175,974,231 		JBrowse link
G Tmem106b transmembrane protein 106B acts_upstream_of_or_within ISO MGI:5319917 (PMID:28728022) RGD PMID:28728022 NCBI chr 4:42,294,074...42,313,426
Ensembl chr 4:41,327,994...41,345,619 		JBrowse link
G Tmem199 transmembrane protein 199 involved_in ISO
ISS
IEA		 (PMID:28296633)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:28296633 GO_REF:0000024 GO_REF:0000107 NCBI chr10:63,900,543...63,905,115
Ensembl chr10:63,402,494...63,407,108 		JBrowse link
G Tmem9 transmembrane protein 9 involved_in ISO
IEA		 (PMID:30374053)
GO_REF:0000107		 RGD
Ensembl		 PMID:30374053 GO_REF:0000107 NCBI chr13:50,008,829...50,027,556
Ensembl chr13:47,458,498...47,475,832 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    biological regulation 13841
      regulation of biological quality 3470
        regulation of intracellular pH 83
          intracellular pH reduction 47
            vacuolar acidification 25
              lysosomal lumen acidification 14
Path 2
Term Annotations click to browse term
  biological_process 20567
    homeostatic process 2032
      chemical homeostasis 1241
        monoatomic ion homeostasis 687
          monoatomic cation homeostasis 673
            regulation of pH 107
              regulation of cellular pH 92
                regulation of intracellular pH 83
                  intracellular pH reduction 47
                    vacuolar acidification 25
                      lysosomal lumen acidification 14
paths to the root