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ONTOLOGY REPORT - ANNOTATIONS


Term:endosome organization
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Accession:GO:0007032 term browser browse the term
Definition:A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes.
Synonyms:exact_synonym: endosome organisation
 related_synonym: endosome organization and biogenesis



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endosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aktip AKT interacting protein involved_in ISO
IEA
ISS
(PMID:18799622)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:18799622 GO_REF:0000024 GO_REF:0000107 NCBI chr19:32,039,507...32,059,634
Ensembl chr19:15,866,928...15,886,663
JBrowse link
G Anxa8 annexin A8 involved_in ISO
IBA
(PMID:18923148)
GO_REF:0000033
RGD
GO_Central
PMID:18923148 GO_REF:0000033 NCBI chr16:9,403,267...9,418,317
Ensembl chr16:9,397,113...9,412,043
JBrowse link
G Arfgef2 ARF guanine nucleotide exchange factor 2 involved_in ISO
IEA
ISS
(PMID:20360857)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:20360857 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:175,966,575...176,052,715
Ensembl chr 3:155,547,538...155,630,856
JBrowse link
G Cc2d1a coiled-coil and C2 domain containing 1A acts_upstream_of_or_within ISO
IEA
MGI:6458917 (PMID:26720614)
GO_REF:0000107
RGD
Ensembl
PMID:26720614 GO_REF:0000107 NCBI chr19:40,916,587...40,931,702
Ensembl chr19:24,011,938...24,026,936
JBrowse link
G Chmp2b charged multivesicular body protein 2B involved_in ISO
IEA
(PMID:16041373)
GO_REF:0000107
RGD
Ensembl
PMID:16041373 GO_REF:0000107 NCBI chr11:16,783,971...16,810,500
Ensembl chr11:3,337,494...3,385,181
JBrowse link
G Dnajc13 DnaJ heat shock protein family (Hsp40) member C13 involved_in ISO
IEA
(PMID:24643499)
GO_REF:0000002
GO_REF:0000107
RGD
InterPro
Ensembl
PMID:24643499 GO_REF:0000002 GO_REF:0000107 NCBI chr 8:113,646,573...113,756,104
Ensembl chr 8:104,767,788...104,877,317
JBrowse link
G Dnm1 dynamin 1 involved_in ISO
IEA
(PMID:19706678)
GO_REF:0000107
RGD
Ensembl
PMID:19706678 GO_REF:0000107 NCBI chr 3:36,002,535...36,055,220
Ensembl chr 3:15,604,784...15,648,538
JBrowse link
G Exoc8 exocyst complex component 8 involved_in ISO (PMID:24344185) RGD PMID:24344185 NCBI chr19:69,752,387...69,754,876
Ensembl chr19:52,852,578...52,857,491
JBrowse link
G Fhip1b FHF complex subunit HOOK interacting protein 1B involved_in ISO
IBA
ISS
(PMID:18799622)
GO_REF:0000033
GO_REF:0000024
RGD
GO_Central
UniProt
PMID:18799622 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:169,137,866...169,160,305
Ensembl chr 1:159,726,004...159,748,408
JBrowse link
G Hook1 hook microtubule-tethering protein 1 involved_in ISO (PMID:18799622) RGD PMID:18799622 NCBI chr 5:115,940,199...116,003,482
Ensembl chr 5:110,824,501...110,887,787
JBrowse link
G Hook2 hook microtubule-tethering protein 2 involved_in ISO (PMID:18799622) RGD PMID:18799622 NCBI chr19:40,056,732...40,075,027
Ensembl chr19:23,151,870...23,164,181
JBrowse link
G Hook3 hook microtubule-tethering protein 3 involved_in ISO
IEA
(PMID:18799622)
GO_REF:0000107
RGD
Ensembl
PMID:18799622 GO_REF:0000107 NCBI chr16:72,656,929...72,751,696
Ensembl chr16:65,954,350...66,061,338
JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:19177150)
UniProt
RGD
PMID:19177150 GO_REF:0000024 NCBI chr 1:165,684,001...165,689,698
Ensembl chr 1:156,272,064...156,291,179
JBrowse link
G Lamtor1l1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 like 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr  X:38,446,140...38,447,189
Ensembl chr  X:34,637,459...34,638,516
JBrowse link
G Laptm4b lysosomal protein transmembrane 4 beta involved_in ISO
IEA
ISS
(PMID:21224396)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:21224396 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:67,319,438...67,362,547
Ensembl chr 7:65,434,394...65,477,383
JBrowse link
G Pheta1 PH domain containing endocytic trafficking adaptor 1 involved_in ISO
IBA
(PMID:21233288)
GO_REF:0000033
RGD
GO_Central
PMID:21233288 GO_REF:0000033 NCBI chr12:40,372,553...40,378,321
Ensembl chr12:34,711,810...34,717,081
JBrowse link
G Pheta2 PH domain containing endocytic trafficking adaptor 2 involved_in ISO
IEA
IBA
(PMID:21233288)
GO_REF:0000104
GO_REF:0000033
RGD
UniProt
GO_Central
PMID:21233288 GO_REF:0000033 GO_REF:0000104 NCBI chr 7:115,735,499...115,741,988
Ensembl chr 7:113,857,249...113,861,871
JBrowse link
G Pi4k2a phosphatidylinositol 4-kinase type 2 alpha involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:250,850,440...250,878,399
Ensembl chr 1:240,902,855...240,929,337
JBrowse link
G Pi4k2b phosphatidylinositol 4-kinase type 2 beta involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:62,434,589...62,461,507
Ensembl chr14:58,220,437...58,248,673
JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 IMP RGD PMID:12453151 RGD:2303129 NCBI chr18:22,119,677...22,203,546
Ensembl chr18:21,845,295...21,929,048
JBrowse link
G Plekha3 pleckstrin homology domain containing A3 involved_in IBA
IEA
GO_REF:0000033
GO_REF:0000104
GO_Central
UniProt
GO_REF:0000033 GO_REF:0000104 NCBI chr 3:82,030,653...82,051,866
Ensembl chr 3:61,623,434...61,645,166
JBrowse link
G Plekhf1 pleckstrin homology and FYVE domain containing 1 involved_in ISO
IBA
(PMID:22115783)
GO_REF:0000033
RGD
GO_Central
PMID:22115783 GO_REF:0000033 NCBI chr 1:100,045,340...100,046,817
Ensembl chr 1:90,904,742...90,915,820
JBrowse link
G Plekhf2 pleckstrin homology and FYVE domain containing 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:28,888,358...28,905,350
Ensembl chr 5:24,090,688...24,106,601
JBrowse link
G Rab22a RAB22A, member RAS oncogene family involved_in ISO
IEA
(PMID:11870209)
GO_REF:0000107
RGD
Ensembl
PMID:11870209 GO_REF:0000107 NCBI chr 3:162,459,727...162,506,129
Ensembl chr 3:162,459,726...162,506,137
JBrowse link
G Rab5a RAB5A, member RAS oncogene family involved_in IMP PMID:8043272 ParkinsonsUK-UCL PMID:8043272 RGD:2306269 NCBI chr 9:6,720,057...6,749,456
Ensembl chr 9:6,484,469...6,512,873
JBrowse link
G Rab5al1 Rab5a, member RAS oncogene family-like 1 involved_in IMP PMID:8043272 ParkinsonsUK-UCL PMID:8043272 RGD:2306269 NCBI chr14:72,544,798...72,546,910
Ensembl chr14:68,332,558...68,333,205
JBrowse link
G Rab5b RAB5B, member RAS oncogene family acts_upstream_of_or_within ISO
IEA
(PMID:7789520)
GO_REF:0000107
RGD
Ensembl
PMID:7789520 GO_REF:0000107 NCBI chr 7:1,693,971...1,712,936
Ensembl chr 7:1,109,454...1,128,268
JBrowse link
G Rab5c RAB5C, member RAS oncogene family acts_upstream_of_or_within ISO (PMID:7789520) RGD PMID:7789520 NCBI chr10:86,142,872...86,166,449
Ensembl chr10:85,642,809...85,666,103
JBrowse link
G Rnf26 ring finger protein 26 involved_in ISO (PMID:27368102) RGD PMID:27368102 NCBI chr 8:53,351,388...53,353,586
Ensembl chr 8:44,454,292...44,457,331
JBrowse link
G Snx10 sorting nexin 10 involved_in ISO
IEA
(PMID:17012226)
GO_REF:0000107
RGD
Ensembl
PMID:17012226 GO_REF:0000107 NCBI chr 4:81,943,262...82,007,667
Ensembl chr 4:80,612,669...80,676,996
JBrowse link
G Snx33 sorting nexin 33 involved_in ISO
IEA
(PMID:21048941)
GO_REF:0000107
RGD
Ensembl
PMID:21048941 GO_REF:0000107 NCBI chr 8:66,213,133...66,224,926
Ensembl chr 8:57,317,161...57,327,538
JBrowse link
G Sqstm1 sequestosome 1 involved_in ISS
IEA
IBA
ISO
GO_REF:0000024
GO_REF:0000107
GO_REF:0000033
(PMID:27368102)
UniProt
Ensembl
GO_Central
RGD
PMID:27368102 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Stx6 syntaxin 6 acts_upstream_of_or_within ISO (PMID:14668490) RGD PMID:14668490 NCBI chr13:69,882,647...69,928,895
Ensembl chr13:67,332,314...67,378,576
JBrowse link
G Tmem127 transmembrane protein 127 acts_upstream_of_or_within ISO
IEA
MGI:5581337 (PMID:24334765)
GO_REF:0000107
RGD
Ensembl
PMID:24334765 GO_REF:0000107 NCBI chr 3:134,919,416...134,932,210
Ensembl chr 3:114,466,171...114,477,519
JBrowse link
G Ubr4 ubiquitin protein ligase E3 component n-recognin 4 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:30111582)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:30111582 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:156,919,029...157,027,127
Ensembl chr 5:151,635,868...151,743,784
JBrowse link
G Usp50 ubiquitin specific peptidase 50 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:134,465,469...134,488,859
Ensembl chr 3:114,011,702...114,035,476
JBrowse link
G Usp8 ubiquitin specific peptidase 8 involved_in ISO
IEA
IBA
(PMID:16771824)
GO_REF:0000107
GO_REF:0000033
RGD
Ensembl
GO_Central
PMID:16771824 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:134,413,832...134,463,040
Ensembl chr 3:113,962,164...114,009,666
JBrowse link
G Vps11 VPS11 core subunit of CORVET and HOPS complexes involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:53,580,939...53,595,378
Ensembl chr 8:44,684,127...44,698,568
JBrowse link
G Vps18 VPS18 core subunit of CORVET and HOPS complexes involved_in
acts_upstream_of_or_within
ISO
IEA
IBA
(PMID:18799622)
GO_REF:0000107
(PMID:14668490)
GO_REF:0000033
RGD
Ensembl
GO_Central
PMID:14668490 PMID:18799622 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:126,733,276...126,744,130
Ensembl chr 3:106,279,425...106,291,964
JBrowse link
G Vps33b VPS33B, late endosome and lysosome associated involved_in ISO (PMID:23918659) RGD PMID:23918659 NCBI chr 1:143,633,167...143,656,228
Ensembl chr 1:134,223,949...134,246,970
JBrowse link
G Vps4a vacuolar protein sorting 4 homolog A acts_upstream_of_or_within ISO
IEA
MGI:1100499 (PMID:26720614)
GO_REF:0000107
RGD
Ensembl
PMID:26720614 GO_REF:0000107 NCBI chr19:51,838,411...51,858,639
Ensembl chr19:34,934,961...34,948,887
JBrowse link
G Vps4b vacuolar protein sorting 4 homolog B acts_upstream_of_or_within ISO MGI:1890520 (PMID:10637304), (PMID:26720614) RGD PMID:10637304 PMID:26720614 NCBI chr13:23,421,758...23,446,848
Ensembl chr13:22,907,109...22,932,229
JBrowse link
G Washc1 WASH complex subunit 1 involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:20175130)
GO_REF:0000107
(PMID:26965651)
RGD
Ensembl
PMID:20175130 PMID:26965651 GO_REF:0000107 NCBI chr 9:113,169,730...113,179,829
Ensembl chr 9:105,722,899...105,733,009
JBrowse link
G Washc4 WASH complex subunit 4 involved_in ISO
IBA
(PMID:23676666)
GO_REF:0000033
RGD
GO_Central
PMID:23676666 GO_REF:0000033 NCBI chr 7:22,075,546...22,127,847
Ensembl chr 7:20,187,922...20,240,226
JBrowse link
G Washc5 WASH complex subunit 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:92,773,625...92,825,532
Ensembl chr 7:90,884,197...90,936,103
JBrowse link
endosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp11 aquaporin 11 acts_upstream_of_or_within ISO MGI:3528447 (PMID:16107722) RGD PMID:16107722 NCBI chr 1:161,457,752...161,467,918
Ensembl chr 1:152,046,517...152,056,725
JBrowse link
G Faslg Fas ligand IDA RGD PMID:18045865 RGD:2315735 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Rnasek ribonuclease K involved_in ISO UniProtKB:Q15904 (PMID:26212330) RGD PMID:26212330 NCBI chr10:55,453,561...55,455,279
Ensembl chr10:54,951,991...54,956,601
JBrowse link
G Tmem9 transmembrane protein 9 involved_in ISO
IEA
(PMID:30374053)
GO_REF:0000107
RGD
Ensembl
PMID:30374053 GO_REF:0000107 NCBI chr13:50,008,829...50,027,556
Ensembl chr13:47,458,498...47,475,832
JBrowse link
endosome membrane tubulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coro1c coronin 1C involved_in ISO
IEA
(PMID:30220460)
GO_REF:0000107
RGD
Ensembl
PMID:30220460 GO_REF:0000107 NCBI chr12:48,373,573...48,445,718
Ensembl chr12:42,712,991...42,785,179
JBrowse link
G Micall2 MICAL-like 2 involved_in ISO (PMID:33976349) RGD PMID:33976349 NCBI chr12:20,013,037...20,041,795
Ensembl chr12:14,899,157...14,927,946
JBrowse link
G Tmcc1 transmembrane and coiled-coil domain family 1 involved_in ISO
IBA
(PMID:30220460)
GO_REF:0000033
RGD
GO_Central
PMID:30220460 GO_REF:0000033 NCBI chr 4:150,738,966...150,912,256
Ensembl chr 4:149,069,260...149,239,620
JBrowse link
intralumenal vesicle formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rilp Rab interacting lysosomal protein involved_in ISO (PMID:17959629) RGD PMID:17959629 NCBI chr10:60,853,316...60,857,096
Ensembl chr10:60,355,278...60,358,781
JBrowse link
G Snx3 sorting nexin 3 involved_in ISO (PMID:18767904) RGD PMID:18767904 NCBI chr20:47,574,051...47,607,577
Ensembl chr20:45,992,720...46,025,379
JBrowse link
multivesicular body assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rab11a RAB11a, member RAS oncogene family involved_in ISO
IEA
(PMID:15634213)
GO_REF:0000107
RGD
Ensembl
PMID:15634213 GO_REF:0000107 NCBI chr 8:74,118,922...74,141,760
Ensembl chr 8:65,222,949...65,246,525
JBrowse link
G Snf8 SNF8 subunit of ESCRT-II involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:38423010)
UniProt
Ensembl
RGD
PMID:38423010 GO_REF:0000024 GO_REF:0000107 NCBI chr10:81,481,054...81,493,430
Ensembl chr10:80,984,363...80,996,734
JBrowse link
G Vps4a vacuolar protein sorting 4 homolog A involved_in IEA
ISO
GO_REF:0000107
(PMID:21238931)
Ensembl
RGD
PMID:21238931 GO_REF:0000107 NCBI chr19:51,838,411...51,858,639
Ensembl chr19:34,934,961...34,948,887
JBrowse link
G Vps4b vacuolar protein sorting 4 homolog B involved_in ISO (PMID:21238931) RGD PMID:21238931 NCBI chr13:23,421,758...23,446,848
Ensembl chr13:22,907,109...22,932,229
JBrowse link
multivesicular body organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rab27a RAB27A, member RAS oncogene family involved_in ISO
IEA
(PMID:23092844)
GO_REF:0000107
RGD
Ensembl
PMID:23092844 GO_REF:0000107 NCBI chr 8:82,663,373...82,717,267
Ensembl chr 8:73,782,694...73,847,829
JBrowse link
negative regulation of intralumenal vesicle formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA
(PMID:26911690)
GO_REF:0000107
RGD
Ensembl
PMID:26911690 GO_REF:0000107 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
positive regulation of endosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Synj1 synaptojanin 1 involved_in ISO
IEA
(PMID:22511594)
GO_REF:0000107
RGD
Ensembl
PMID:22511594 GO_REF:0000107 NCBI chr11:43,678,709...43,755,526
Ensembl chr11:30,192,629...30,269,220
JBrowse link
regulation of endosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tom1 target of myb1 membrane trafficking protein involved_in ISO
IEA
(PMID:25588840)
GO_REF:0000107
RGD
Ensembl
PMID:25588840 GO_REF:0000107 NCBI chr19:13,411,227...13,446,129
Ensembl chr19:13,405,501...13,440,384
JBrowse link
synaptic vesicle to endosome fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stx12 syntaxin 12 involved_in IDA
IMP
PMID:17004320 SynGO PMID:17004320 PMID:17004320 RGD:12050136, RGD:12050136 NCBI chr 5:150,347,554...150,376,426
Ensembl chr 5:145,063,587...145,092,377
JBrowse link
G Stx6 syntaxin 6 involved_in IDA
IMP
PMID:17004320 SynGO PMID:17004320 PMID:17004320 RGD:12050136, RGD:12050136 NCBI chr13:69,882,647...69,928,895
Ensembl chr13:67,332,314...67,378,576
JBrowse link
G Stx7 syntaxin 7 involved_in ISO (PMID:34408265) RGD PMID:34408265 NCBI chr 1:23,016,330...23,056,579
Ensembl chr 1:21,197,075...21,237,279
JBrowse link
G Vamp4 vesicle-associated membrane protein 4 involved_in IDA
IEP
IMP
PMID:17004320
PMID:26607000
SynGO PMID:17004320 PMID:26607000 PMID:17004320 PMID:26607000 PMID:26607000 RGD:12050136, RGD:11058152, RGD:12050136, RGD:11058152, RGD:11058152 NCBI chr13:77,453,135...77,475,909
Ensembl chr13:74,919,880...74,933,686
JBrowse link
G Vti1a vesicle transport through interaction with t-SNAREs 1A involved_in IMP
IDA
PMID:17004320 SynGO PMID:17004320 PMID:17004320 RGD:12050136, RGD:12050136 NCBI chr 1:264,361,538...264,667,171
Ensembl chr 1:254,356,429...254,661,852
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      cellular component organization or biogenesis 7104
        cellular component organization 6817
          endomembrane system organization 587
            endosome organization 64
              endosomal lumen acidification 4
              endosome membrane tubulation 3
              intralumenal vesicle formation + 3
              multivesicular body organization + 5
              negative regulation of endosome organization + 1
              positive regulation of endosome organization + 1
              regulation of endosome organization + 3
              synaptic vesicle to endosome fusion + 5
Path 2
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      cellular component organization or biogenesis 7104
        cellular component organization 6817
          organelle organization 3713
            vesicle organization 372
              endosome organization 64
                endosomal lumen acidification 4
                endosome membrane tubulation 3
                intralumenal vesicle formation + 3
                multivesicular body organization + 5
                negative regulation of endosome organization + 1
                positive regulation of endosome organization + 1
                regulation of endosome organization + 3
                synaptic vesicle to endosome fusion + 5
paths to the root