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ONTOLOGY REPORT - ANNOTATIONS

Term:humoral immune response
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Accession:GO:0006959 term browser browse the term
Definition:An immune response mediated through a body fluid.
Synonyms:xref: Wikipedia:Humoral_immunity

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humoral immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aire autoimmune regulator acts_upstream_of_or_within ISO (PMID:11854172) MGI PMID:11854172 NCBI chrNW_004955407:41,157,503...41,165,032
Ensembl chrNW_004955407:41,157,484...41,165,014 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase involved_in ISO (PMID:21224059) UniProt PMID:21224059 NCBI chrNW_004955546:2,495,226...2,550,909
Ensembl chrNW_004955546:2,494,819...2,550,909 		JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger acts_upstream_of_or_within ISO (PMID:7926765) MGI PMID:7926765 NCBI chrNW_004955429:6,548,586...6,553,730
Ensembl chrNW_004955429:6,547,731...6,558,105 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 acts_upstream_of_or_within ISO (PMID:10899907) MGI PMID:10899907 NCBI chrNW_004955420:25,641,184...25,664,413 JBrowse link
G Foxj1 forkhead box J1 involved_in ISO (PMID:16339515) BHF-UCL PMID:16339515 NCBI chrNW_004955506:6,127,551...6,132,302
Ensembl chrNW_004955506:6,127,551...6,132,302 		JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO (PMID:17658279) MGI PMID:17658279 NCBI chrNW_004955421:24,448,446...24,477,885
Ensembl chrNW_004955421:24,457,496...24,478,744 		JBrowse link
G Gpr183 G protein-coupled receptor 183 involved_in ISO (PMID:19597478), (PMID:23502855), (PMID:23682316) UniProt PMID:19597478 PMID:23502855 PMID:23682316 NCBI chrNW_004955404:11,264,954...11,277,531
Ensembl chrNW_004955404:11,264,954...11,277,531 		JBrowse link
G Ifnb1 interferon beta 1 acts_upstream_of_or_within ISO (PMID:17277142) MGI PMID:17277142 NCBI chrNW_004955434:23,301,623...23,302,304 JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:17277142) MGI PMID:17277142 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045 		JBrowse link
G Lta lymphotoxin alpha acts_upstream_of_or_within ISO (PMID:7636227) MGI PMID:7636227 NCBI chrNW_004955437:114,216...116,003
Ensembl chrNW_004955437:114,640...115,529 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISO (PMID:18955699) UniProt PMID:18955699 NCBI chrNW_004955418:22,537,388...22,701,434
Ensembl chrNW_004955418:22,537,285...22,701,434 		JBrowse link
G Notch1 notch receptor 1 acts_upstream_of_or_within ISO (PMID:17658279) MGI PMID:17658279 NCBI chrNW_004955513:4,225,939...4,264,875
Ensembl chrNW_004955513:4,225,956...4,263,259 		JBrowse link
G Notch2 notch receptor 2 acts_upstream_of_or_within ISO (PMID:17658279) MGI PMID:17658279 NCBI chrNW_004955568:1,660,357...1,812,285
Ensembl chrNW_004955568:1,660,731...1,809,173 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region acts_upstream_of_or_within ISO (PMID:17658279) MGI PMID:17658279 NCBI chrNW_004955443:18,783,061...19,029,441
Ensembl chrNW_004955443:18,783,061...18,910,228 		JBrowse link
G Sh2d1a SH2 domain containing 1A acts_upstream_of_or_within ISO (PMID:12529646) MGI PMID:12529646 NCBI chrNW_004955473:10,345,407...10,370,535
Ensembl chrNW_004955473:10,346,943...10,370,575 		JBrowse link
G Tfe3 transcription factor binding to IGHM enhancer 3 involved_in ISO (PMID:16936731) UniProt PMID:16936731 NCBI chrNW_004955543:547,037...561,073
Ensembl chrNW_004955543:547,037...561,073 		JBrowse link
G Tfeb transcription factor EB involved_in ISO (PMID:16936731) UniProt PMID:16936731 NCBI chrNW_004955437:8,102,241...8,141,001
Ensembl chrNW_004955437:8,098,976...8,141,001 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO (PMID:8879212) MGI PMID:8879212 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700 		JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 involved_in ISO (PMID:11485735) UniProt PMID:11485735 NCBI chrNW_004955437:11,877,051...11,915,220
Ensembl chrNW_004955437:11,876,895...11,915,460 		JBrowse link
G Traf3ip2 TRAF3 interacting protein 2 acts_upstream_of_or_within ISO (PMID:15485634) MGI PMID:15485634 NCBI chrNW_004955411:36,328,152...36,363,614
Ensembl chrNW_004955411:36,326,926...36,363,288 		JBrowse link
antibacterial humoral response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO PMID:20209079 UniProt PMID:20209079 RGD:10400853 NCBI chrNW_004955407:25,725,259...25,973,582
Ensembl chrNW_004955407:25,722,849...25,974,268 		JBrowse link
G Bpifa1 BPI fold containing family A member 1 involved_in ISO (PMID:23499554) UniProt PMID:23499554 NCBI chrNW_004955422:28,063,077...28,069,939 JBrowse link
G Ltf lactotransferrin involved_in ISO (PMID:1599934), (PMID:18714013) UniProt PMID:1599934 PMID:18714013 NCBI chrNW_004955420:25,580,449...25,604,277
Ensembl chrNW_004955420:25,580,359...25,604,331 		JBrowse link
G Pla2g6 phospholipase A2 group VI involved_in ISO (PMID:18714013) UniProt PMID:18714013 NCBI chrNW_004955413:24,431,592...24,482,229
Ensembl chrNW_004955413:24,429,589...24,482,537 		JBrowse link
G Rnase6 ribonuclease A family member 6 involved_in ISO (PMID:25075772) UniProt PMID:25075772 NCBI chrNW_004955550:1,687,068...1,688,160 JBrowse link
G Rnase7 ribonuclease A family member 7 involved_in ISO (PMID:25075772) UniProt PMID:25075772 NCBI chrNW_004955550:1,796,301...1,797,801 JBrowse link
antibacterial peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals4 galectin 4 acts_upstream_of_or_within ISO (PMID:27427436) MGI PMID:27427436 NCBI chrNW_004955468:694,831...701,623
Ensembl chrNW_004955468:694,873...701,535 		JBrowse link
G Mmp7 matrix metallopeptidase 7 acts_upstream_of_or_within ISO (PMID:20056603) MGI PMID:20056603 NCBI chrNW_004955412:5,780,772...5,792,485
Ensembl chrNW_004955412:5,778,502...5,792,445 		JBrowse link
antibacterial peptide secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmp7 matrix metallopeptidase 7 acts_upstream_of_or_within ISO (PMID:11248802) MGI PMID:11248802 NCBI chrNW_004955412:5,780,772...5,792,485
Ensembl chrNW_004955412:5,778,502...5,792,445 		JBrowse link
antifungal humoral response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO PMID:20209079 UniProt PMID:20209079 RGD:10400853 NCBI chrNW_004955407:25,725,259...25,973,582
Ensembl chrNW_004955407:25,722,849...25,974,268 		JBrowse link
G Il36rn interleukin 36 receptor antagonist involved_in ISO (PMID:23147407) UniProt PMID:23147407 NCBI chrNW_004955470:1,209,389...1,214,730
Ensembl chrNW_004955470:1,209,325...1,214,821 		JBrowse link
antimicrobial humoral immune response mediated by antimicrobial peptide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin involved_in ISO (PMID:10225288) UniProt PMID:10225288 NCBI chrNW_004955414:25,951,473...25,953,593
Ensembl chrNW_004955414:25,951,349...25,953,645 		JBrowse link
G App amyloid beta precursor protein involved_in ISO PMID:20209079
(PMID:20209079)		 UniProt PMID:20209079 RGD:10400853 NCBI chrNW_004955407:25,725,259...25,973,582
Ensembl chrNW_004955407:25,722,849...25,974,268 		JBrowse link
G B2m beta-2-microglobulin involved_in ISO (PMID:23144825) UniProt PMID:23144825 NCBI chrNW_004955416:11,205,503...11,211,325
Ensembl chrNW_004955416:11,204,849...11,215,568 		JBrowse link
G Bpifa1 BPI fold containing family A member 1 involved_in ISO (PMID:21805676) UniProt PMID:21805676 NCBI chrNW_004955422:28,063,077...28,069,939 JBrowse link
G Camp cathelicidin antimicrobial peptide involved_in ISO (PMID:17012259)
(PMID:12759353), (PMID:12860195), (PMID:14978112), (PMID:20209079), (PMID:20421939), (PMID:23537644), (PMID:7529412), (PMID:9182550)		 UniProt PMID:7529412 PMID:9182550 PMID:12759353 PMID:12860195 PMID:14978112 More... NCBI chrNW_004955420:24,911,920...24,914,698 JBrowse link
G Ccl1 C-C motif chemokine ligand 1 involved_in ISO (PMID:12949249) UniProt PMID:12949249 NCBI chrNW_004955481:9,085,943...9,089,147 JBrowse link
G Ccl17 C-C motif chemokine ligand 17 involved_in ISO (PMID:12949249) UniProt PMID:12949249 NCBI chrNW_004955433:15,052,616...15,054,732
Ensembl chrNW_004955433:15,053,061...15,054,572 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO (PMID:12949249) UniProt PMID:12949249 NCBI chrNW_004955472:1,444,598...1,446,488
Ensembl chrNW_004955472:1,444,316...1,446,490 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 involved_in ISO (PMID:12949249), (PMID:19109182) UniProt PMID:12949249 PMID:19109182 NCBI chrNW_004955453:6,846,625...6,850,007
Ensembl chrNW_004955453:6,846,549...6,850,031 		JBrowse link
G Ccl21 C-C motif chemokine ligand 21 involved_in ISO (PMID:12949249) UniProt PMID:12949249 NCBI chrNW_004955472:1,427,660...1,428,771
Ensembl chrNW_004955472:1,427,710...1,429,102 		JBrowse link
G Ccl22 C-C motif chemokine ligand 22 involved_in ISO (PMID:12949249) UniProt PMID:12949249 NCBI chrNW_004955433:15,002,001...15,007,324
Ensembl chrNW_004955433:15,001,930...15,008,032 		JBrowse link
G Ccl25 C-C motif chemokine ligand 25 involved_in ISO (PMID:12949249) UniProt PMID:12949249 NCBI chrNW_004955563:1,249,098...1,255,469 JBrowse link
G Ccl27 C-C motif chemokine ligand 27 involved_in ISO (PMID:19109182) UniProt PMID:19109182 NCBI chrNW_004955472:1,470,407...1,474,800
Ensembl chrNW_004955472:1,471,551...1,474,777 		JBrowse link
G Ccl28 C-C motif chemokine ligand 28 involved_in ISO (PMID:12538707) UniProt PMID:12538707 NCBI chrNW_004955446:18,902,465...18,925,178
Ensembl chrNW_004955446:18,902,636...18,925,561 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 involved_in ISO (PMID:12949249) UniProt PMID:12949249 NCBI chrNW_004955433:748,392...750,890
Ensembl chrNW_004955433:748,284...750,927 		JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 involved_in ISO (PMID:12949249) UniProt PMID:12949249 NCBI chrNW_004955433:769,449...771,137
Ensembl chrNW_004955433:766,272...771,231 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 involved_in ISO (PMID:12949249) UniProt PMID:12949249 NCBI chrNW_004955546:1,929,269...1,941,690
Ensembl chrNW_004955546:1,929,269...1,941,690 		JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 involved_in ISO (PMID:12949249) UniProt PMID:12949249 NCBI chrNW_004955433:2,123,190...2,129,119 JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 involved_in ISO (PMID:12949249), (PMID:19109182)
(PMID:19109182)		 UniProt PMID:12949249 PMID:19109182 NCBI chrNW_004955408:30,733,079...30,740,854
Ensembl chrNW_004955408:30,733,079...30,740,854 		JBrowse link
G Cxcl8 C-X-C motif chemokine ligand 8 involved_in ISO (PMID:19109182) UniProt PMID:19109182 NCBI chrNW_004955474:247,326...250,355
Ensembl chrNW_004955474:241,501...250,643 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 involved_in ISO (PMID:12949249) UniProt PMID:12949249 NCBI chrNW_004955433:724,566...731,945
Ensembl chrNW_004955433:724,515...732,192 		JBrowse link
G Dcd dermcidin involved_in ISO (PMID:11694882) UniProt PMID:11694882 NCBI chrNW_004955458:1,875,244...1,879,434 JBrowse link
G Defb118 defensin beta 118 involved_in ISO (PMID:15033915) UniProt PMID:15033915 NCBI chrNW_004955422:29,554,310...29,560,660 JBrowse link
G Defb127 defensin beta 127 involved_in ISO (PMID:19373462) UniProt PMID:19373462 NCBI chrNW_004955597:38,613...40,241 JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 involved_in ISO (PMID:11007786) UniProt PMID:11007786 NCBI chrNW_004955477:863,388...899,703 JBrowse link
G F2 coagulation factor II, thrombin involved_in ISO (PMID:20421939) UniProt PMID:20421939 NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517 		JBrowse link
G Fam3a FAM3 metabolism regulating signaling molecule A involved_in ISO (PMID:18212107) UniProt PMID:18212107 NCBI chrNW_004955580:1,025,481...1,036,752
Ensembl chrNW_004955580:1,029,553...1,036,849 		JBrowse link
G Fau FAU ubiquitin like and ribosomal protein S30 fusion involved_in ISO (PMID:10496312)
(PMID:12860195)		 UniProt PMID:10496312 PMID:12860195 NCBI chrNW_004955422:20,078,393...20,080,855
Ensembl chrNW_004955422:20,078,393...20,080,855 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase involved_in ISO (PMID:22832495) UniProt PMID:22832495 NCBI chrNW_004955413:4,162,467...4,166,783
Ensembl chrNW_004955413:4,162,467...4,166,783 		JBrowse link
G Hamp hepcidin antimicrobial peptide involved_in ISO (PMID:11034317), (PMID:11113131) UniProt PMID:11034317 PMID:11113131 NCBI chrNW_004955468:4,576,080...4,577,591
Ensembl chrNW_004955468:4,575,510...4,577,649 		JBrowse link
G Hmgn2 high mobility group nucleosomal binding domain 2 involved_in ISO (PMID:16204630) UniProt PMID:16204630 NCBI chrNW_004955452:5,846,085...5,849,996
Ensembl chrNW_004955452:5,846,085...5,849,996 		JBrowse link
G Hrg histidine rich glycoprotein involved_in ISO (PMID:18797515) UniProt PMID:18797515 NCBI chrNW_004955420:21,020,938...21,033,022
Ensembl chrNW_004955420:21,019,212...21,032,976 		JBrowse link
G Krt6a keratin 6A involved_in ISO (PMID:23006328) UniProt PMID:23006328 NCBI chrNW_004955547:2,902,962...2,907,670 JBrowse link
G Leap2 liver enriched antimicrobial peptide 2 involved_in ISO (PMID:12493837) UniProt PMID:12493837 NCBI chrNW_004955408:4,245,574...4,247,117
Ensembl chrNW_004955408:4,245,574...4,247,117 		JBrowse link
G Lgals3 galectin 3 involved_in ISO (PMID:16982911) UniProt PMID:16982911 NCBI chrNW_004955409:8,448,120...8,452,437
Ensembl chrNW_004955409:8,447,774...8,452,438 		JBrowse link
G LOC102004444 beta-defensin 1-like involved_in ISO (PMID:12860195)
(PMID:25122636)		 UniProt PMID:12860195 PMID:25122636 NCBI chrNW_004955403:53,643,328...53,644,361
Ensembl chrNW_004955403:53,643,300...53,644,505 		JBrowse link
G Ltf lactotransferrin involved_in ISO (PMID:15155221) UniProt PMID:15155221 NCBI chrNW_004955420:25,580,449...25,604,277
Ensembl chrNW_004955420:25,580,359...25,604,331 		JBrowse link
G Muc7 mucin 7, secreted involved_in ISO (PMID:12543672) UniProt PMID:12543672 NCBI chrNW_004955447:2,511,841...2,520,312 JBrowse link
G Nppb natriuretic peptide B involved_in ISO (PMID:11410403) UniProt PMID:11410403 NCBI chrNW_004955486:2,054,775...2,056,130 JBrowse link
G Npy neuropeptide Y involved_in ISO (PMID:18603306) UniProt PMID:18603306 NCBI chrNW_004955410:26,348,388...26,355,232
Ensembl chrNW_004955410:26,348,504...26,355,297 		JBrowse link
G Pglyrp1 peptidoglycan recognition protein 1 involved_in ISO (PMID:16354652) UniProt PMID:16354652 NCBI chrNW_004955574:424,046...427,675
Ensembl chrNW_004955574:424,142...427,540 		JBrowse link
G Pglyrp4 peptidoglycan recognition protein 4 involved_in ISO (PMID:16354652) UniProt PMID:16354652 NCBI chrNW_004955592:100,022...111,609
Ensembl chrNW_004955592:100,088...111,610 		JBrowse link
G Pla2g1b phospholipase A2 group IB involved_in ISO (PMID:12860195) UniProt PMID:12860195 NCBI chrNW_004955455:11,308,848...11,316,245
Ensembl chrNW_004955455:11,308,643...11,316,254 		JBrowse link
G Rnase6 ribonuclease A family member 6 involved_in ISO (PMID:25075772) UniProt PMID:25075772 NCBI chrNW_004955550:1,687,068...1,688,160 JBrowse link
G Rnase7 ribonuclease A family member 7 involved_in ISO (PMID:12244054), (PMID:23302724), (PMID:25075772) GO_Central PMID:12244054 PMID:23302724 PMID:25075772 NCBI chrNW_004955550:1,796,301...1,797,801 JBrowse link
G Romo1 reactive oxygen species modulator 1 involved_in ISO (PMID:22083756) UniProt PMID:22083756 NCBI chrNW_004955422:25,757,558...25,760,054
Ensembl chrNW_004955422:25,757,558...25,759,769 		JBrowse link
G Rpl30 ribosomal protein L30 involved_in ISO (PMID:15019208) UniProt PMID:15019208 NCBI chrNW_004955417:13,764,814...13,767,698
Ensembl chrNW_004955417:13,764,814...13,767,698 		JBrowse link
G Rpl39 ribosomal protein L39 involved_in ISO (PMID:12860195) UniProt PMID:12860195 NCBI chrNW_004955534:200,591...203,827 JBrowse link
G Rps19 ribosomal protein S19 involved_in ISO (PMID:15019208) UniProt PMID:15019208 NCBI chrNW_004955555:969,345...976,122
Ensembl chrNW_004955555:969,340...976,509 		JBrowse link
G Tac1 tachykinin precursor 1 involved_in ISO (PMID:18603306) UniProt PMID:18603306 NCBI chrNW_004955432:13,991,647...13,999,665
Ensembl chrNW_004955432:13,991,414...13,999,728 		JBrowse link
G Tslp thymic stromal lymphopoietin involved_in ISO (PMID:24850429) UniProt PMID:24850429 NCBI chrNW_004955418:4,041,529...4,045,534 JBrowse link
G Vip vasoactive intestinal peptide involved_in ISO (PMID:18603306) UniProt PMID:18603306 NCBI chrNW_004955439:9,021,923...9,031,783
Ensembl chrNW_004955439:9,021,904...9,031,792 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:12949249) UniProt PMID:12949249 NCBI chrNW_004955462:8,594,416...8,598,101 JBrowse link
antimicrobial humoral response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl3 BCL3 transcription coactivator acts_upstream_of_or_within ISO (PMID:9009202) MGI PMID:9009202 NCBI chrNW_004955555:1,898,280...1,911,466
Ensembl chrNW_004955555:1,856,250...1,911,466 		JBrowse link
G Colec11 collectin subfamily member 11 involved_in ISO (PMID:20956340) UniProt PMID:20956340 NCBI chrNW_004955487:3,778,901...3,789,852
Ensembl chrNW_004955487:3,778,858...3,790,080 		JBrowse link
biosynthetic process of antibacterial peptides active against Gram-positive bacteria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of ISO (PMID:15692051) MGI PMID:15692051 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C2 complement C2 involved_in ISO (PMID:19302245) BHF-UCL PMID:19302245 NCBI chrNW_004955437:449,171...460,898
Ensembl chrNW_004955437:448,672...460,519 		JBrowse link
G C3 complement C3 acts_upstream_of_or_within
involved_in		 ISO (PMID:18947875)
(PMID:25284781)
(PMID:19302245)		 RGD
MGI
BHF-UCL		 PMID:18947875 PMID:19302245 PMID:20712003 PMID:25284781 RGD:5129529 NCBI chrNW_004955495:2,796,601...2,824,233
Ensembl chrNW_004955495:2,796,663...2,824,697 		JBrowse link
G C8a complement C8 alpha chain acts_upstream_of_or_within ISO (PMID:12413696) MGI PMID:12413696 NCBI chrNW_004955464:2,806,859...2,874,444 JBrowse link
G Cfb complement factor B ISO RGD PMID:6906329 RGD:2311339 NCBI chrNW_004955437:461,235...466,908
Ensembl chrNW_004955437:461,235...470,464 		JBrowse link
G Cfi complement factor I involved_in ISO (PMID:18202746) MGI PMID:18202746 NCBI chrNW_004955496:492,217...553,398
Ensembl chrNW_004955496:492,167...553,217 		JBrowse link
G Colec11 collectin subfamily member 11 involved_in ISO (PMID:23954398) UniProt PMID:23954398 NCBI chrNW_004955487:3,778,901...3,789,852
Ensembl chrNW_004955487:3,778,858...3,790,080 		JBrowse link
G Fcn3 ficolin 3 involved_in ISO (PMID:22851708) UniProt PMID:22851708 NCBI chrNW_004955452:6,630,548...6,635,334
Ensembl chrNW_004955452:6,630,505...6,635,235 		JBrowse link
complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfb complement factor B acts_upstream_of_or_within ISO (PMID:9238044)
(PMID:27564415)		 MGI PMID:9238044 PMID:27564415 NCBI chrNW_004955437:461,235...466,908
Ensembl chrNW_004955437:461,235...470,464 		JBrowse link
G Cfd complement factor D acts_upstream_of_or_within ISO (PMID:27564415) MGI PMID:27564415 NCBI chrNW_004955495:6,955,612...6,961,317 JBrowse link
G Cfp complement factor properdin involved_in ISO (PMID:18292556) MGI PMID:18292556 NCBI chrNW_004955516:449,993...455,897
Ensembl chrNW_004955516:449,993...456,492 		JBrowse link
G Cr2 complement C3d receptor 2 involved_in
acts_upstream_of_or_within_negative_effect		 ISO (PMID:11981823)
(PMID:19828624)		 ARUK-UCL
MGI		 PMID:11981823 PMID:19828624 NCBI chrNW_004955406:42,877,041...42,910,970
Ensembl chrNW_004955406:42,876,966...42,911,564 		JBrowse link
complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qa complement C1q A chain involved_in
acts_upstream_of_or_within		 ISO (PMID:29449492)
(PMID:11901193)		 ComplexPortal
MGI		 PMID:11901193 PMID:29449492 NCBI chrNW_004955452:2,753,362...2,756,220
Ensembl chrNW_004955452:2,752,970...2,756,488 		JBrowse link
G C1qb complement C1q B chain involved_in ISO (PMID:29449492) ComplexPortal PMID:29449492 NCBI chrNW_004955452:2,765,844...2,771,695
Ensembl chrNW_004955452:2,769,752...2,772,534 		JBrowse link
G C1qc complement C1q C chain involved_in ISO (PMID:29449492) ComplexPortal PMID:29449492 NCBI chrNW_004955452:2,759,079...2,762,522
Ensembl chrNW_004955452:2,758,821...2,762,522 		JBrowse link
complement activation, lectin pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Colec10 collectin subfamily member 10 involved_in ISO (PMID:24174618) ComplexPortal PMID:24174618 NCBI chrNW_004955417:24,954,969...24,994,188
Ensembl chrNW_004955417:24,954,938...24,994,188 		JBrowse link
G Colec11 collectin subfamily member 11 involved_in ISO (PMID:25912189)
(PMID:24174618)		 UniProt
ComplexPortal		 PMID:24174618 PMID:25912189 NCBI chrNW_004955487:3,778,901...3,789,852
Ensembl chrNW_004955487:3,778,858...3,790,080 		JBrowse link
G Fcn1 ficolin 1 involved_in ISO (PMID:16116205) ComplexPortal PMID:16116205 NCBI chrNW_004955513:3,690,550...3,697,785
Ensembl chrNW_004955513:3,687,232...3,698,673 		JBrowse link
G Fcn3 ficolin 3 involved_in ISO (PMID:11907111) UniProt PMID:11907111 NCBI chrNW_004955452:6,630,548...6,635,334
Ensembl chrNW_004955452:6,630,505...6,635,235 		JBrowse link
G Krt1 keratin 1 involved_in ISO (PMID:11549596) UniProt PMID:11549596 NCBI chrNW_004955458:25,193...29,282
Ensembl chrNW_004955458:25,187...29,208 		JBrowse link
G Masp1 MBL associated serine protease 1 involved_in ISO (PMID:17182967)
(PMID:18424734)		 UniProt PMID:17182967 PMID:18424734 NCBI chrNW_004955420:20,540,266...20,605,830
Ensembl chrNW_004955420:20,540,016...20,605,854 		JBrowse link
G Masp2 MBL associated serine protease 2 involved_in ISO (PMID:17182967), (PMID:9087411) UniProt PMID:9087411 PMID:17182967 NCBI chrNW_004955486:2,641,730...2,655,125 JBrowse link
G Mbl2 mannose binding lectin 2 acts_upstream_of_or_within
involved_in		 ISO (PMID:15148336)
(PMID:22691502), (PMID:35102342)
(PMID:11549596)		 MGI
ComplexPortal
UniProt		 PMID:11549596 PMID:15148336 PMID:22691502 PMID:35102342 NCBI chrNW_004955425:7,704,371...7,708,951
Ensembl chrNW_004955425:7,702,137...7,709,006 		JBrowse link
humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl3 BCL3 transcription coactivator acts_upstream_of_or_within ISO (PMID:9009202) MGI PMID:9009202 NCBI chrNW_004955555:1,898,280...1,911,466
Ensembl chrNW_004955555:1,856,250...1,911,466 		JBrowse link
G Cd81 CD81 molecule involved_in ISO (PMID:20237408) UniProt PMID:20237408 NCBI chrNW_004955422:14,155,682...14,175,181
Ensembl chrNW_004955422:14,155,682...14,175,181 		JBrowse link
G Exo1 exonuclease 1 acts_upstream_of_or_within ISO (PMID:14716311) MGI PMID:14716311 NCBI chrNW_004955406:10,248,981...10,276,207
Ensembl chrNW_004955406:10,245,886...10,275,522 		JBrowse link
G Fcmr Fc mu receptor involved_in ISO (PMID:22988094) UniProt PMID:22988094 NCBI chrNW_004955406:42,438,173...42,452,339
Ensembl chrNW_004955406:42,438,783...42,452,163 		JBrowse link
G Zp2 zona pellucida glycoprotein 2 involved_in ISO (PMID:12052239) UniProt PMID:12052239 NCBI chrNW_004955493:400,868...412,660
Ensembl chrNW_004955493:400,868...412,596 		JBrowse link
G Zp3 zona pellucida glycoprotein 3 involved_in ISO (PMID:20382503)
(PMID:12052239)		 UniProt PMID:12052239 PMID:20382503 NCBI chrNW_004955456:15,013,472...15,020,809 JBrowse link
induction of bacterial agglutination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fga fibrinogen alpha chain involved_in ISO (PMID:24367264) CACAO PMID:24367264 NCBI chrNW_004955471:8,806,964...8,814,671
Ensembl chrNW_004955471:8,806,650...8,816,791 		JBrowse link
G Fgb fibrinogen beta chain involved_in ISO (PMID:24367264) CACAO PMID:24367264 NCBI chrNW_004955471:8,824,901...8,832,836
Ensembl chrNW_004955471:8,822,965...8,832,884 		JBrowse link
G Spon2 spondin 2 acts_upstream_of_or_within ISO (PMID:14691481) MGI PMID:14691481 NCBI chrNW_004955514:598,840...603,390
Ensembl chrNW_004955514:596,829...604,051 		JBrowse link
negative regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd59 CD59 molecule (CD59 blood group) acts_upstream_of_or_within ISO (PMID:10946279), (PMID:11471050) RGD
MGI		 PMID:10946279 PMID:11471050 PMID:15843577 RGD:1600482 NCBI chrNW_004955422:12,500,572...12,528,738 JBrowse link
negative regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd55 CD55 molecule (Cromer blood group) involved_in ISO (PMID:6211481)
(PMID:28657829)		 RGD
UniProt		 PMID:6211481 PMID:10929073 PMID:28657829 RGD:2326180 NCBI chrNW_004955406:42,773,368...42,796,205 JBrowse link
G Cd59 CD59 molecule (CD59 blood group) acts_upstream_of_or_within ISO (PMID:10946279) MGI PMID:10946279 NCBI chrNW_004955422:12,500,572...12,528,738 JBrowse link
G Masp1 MBL associated serine protease 1 involved_in ISO (PMID:11485744) UniProt PMID:11485744 NCBI chrNW_004955420:20,540,266...20,605,830
Ensembl chrNW_004955420:20,540,016...20,605,854 		JBrowse link
negative regulation of complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd46 CD46 molecule involved_in ISO (PMID:9029106) AgBase PMID:9029106 NCBI chrNW_004955406:43,002,817...43,034,555 JBrowse link
G Susd4 sushi domain containing 4 involved_in ISO (PMID:23482636) UniProt PMID:23482636 NCBI chrNW_004955520:1,444,618...1,523,214
Ensembl chrNW_004955520:1,444,618...1,523,260 		JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 involved_in ISO (PMID:17051150) UniProt PMID:17051150 NCBI chrNW_004955475:5,461,512...5,481,552
Ensembl chrNW_004955475:5,461,064...5,481,564 		JBrowse link
negative regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C4bpa complement component 4 binding protein alpha involved_in ISO (PMID:22333221) BHF-UCL PMID:22333221 NCBI chrNW_004955406:42,613,659...42,641,918
Ensembl chrNW_004955406:42,613,607...42,641,670 		JBrowse link
G C4bpb complement component 4 binding protein beta involved_in ISO (PMID:22333221) BHF-UCL PMID:22333221 NCBI chrNW_004955406:42,601,164...42,608,912 JBrowse link
G Cd46 CD46 molecule involved_in ISO (PMID:9029106) AgBase PMID:9029106 NCBI chrNW_004955406:43,002,817...43,034,555 JBrowse link
G Susd4 sushi domain containing 4 involved_in ISO (PMID:23482636) UniProt PMID:23482636 NCBI chrNW_004955520:1,444,618...1,523,214
Ensembl chrNW_004955520:1,444,618...1,523,260 		JBrowse link
negative regulation of complement activation, lectin pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC102021956 alpha-2-macroglobulin involved_in ISO (PMID:12538697) UniProt PMID:12538697 NCBI chrNW_004955413:6,019,457...6,062,366
Ensembl chrNW_004955413:6,019,082...6,062,529 		JBrowse link
G Serping1 serpin family G member 1 involved_in ISO (PMID:10946292) UniProt PMID:10946292 NCBI chrNW_004955511:2,545,337...2,557,850
Ensembl chrNW_004955511:2,545,285...2,557,982 		JBrowse link
negative regulation of humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcgr2b Fc fragment of IgG receptor IIb acts_upstream_of_or_within ISO (PMID:12385742) MGI PMID:12385742 NCBI chrNW_004955462:14,639,396...14,653,801 JBrowse link
G Foxj1 forkhead box J1 involved_in ISO (PMID:16002694) BHF-UCL PMID:16002694 NCBI chrNW_004955506:6,127,551...6,132,302
Ensembl chrNW_004955506:6,127,551...6,132,302 		JBrowse link
G Ptpn6 protein tyrosine phosphatase non-receptor type 6 acts_upstream_of_or_within ISO (PMID:9254656) MGI PMID:9254656 NCBI chrNW_004955413:4,525,954...4,547,177
Ensembl chrNW_004955413:4,525,954...4,547,177 		JBrowse link
positive regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in ISO (PMID:15611275) BHF-UCL PMID:15611275 NCBI chrNW_004955495:2,796,601...2,824,233
Ensembl chrNW_004955495:2,796,663...2,824,697 		JBrowse link
positive regulation of antibacterial peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:18167348) MGI PMID:18167348 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
positive regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Klk5 kallikrein related peptidase 5 involved_in ISO (PMID:17012259) UniProt PMID:17012259 NCBI chrNW_004955558:1,512,478...1,520,522
Ensembl chrNW_004955558:1,511,818...1,520,613 		JBrowse link
G Klk7 kallikrein related peptidase 7 involved_in ISO (PMID:17012259) UniProt PMID:17012259 NCBI chrNW_004955558:1,490,884...1,494,843
Ensembl chrNW_004955558:1,490,120...1,494,993 		JBrowse link
G Pgc progastricsin involved_in ISO (PMID:12759353) UniProt PMID:12759353 NCBI chrNW_004955437:8,142,523...8,153,044
Ensembl chrNW_004955437:8,142,661...8,151,339 		JBrowse link
positive regulation of antimicrobial humoral response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (PMID:23610393) UniProt PMID:23610393 NCBI chrNW_004955404:30,254,934...30,266,898
Ensembl chrNW_004955404:30,254,841...30,270,921 		JBrowse link
G Camp cathelicidin antimicrobial peptide ISO RGD PMID:18227173 RGD:438738460 NCBI chrNW_004955420:24,911,920...24,914,698 JBrowse link
positive regulation of antimicrobial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il17a interleukin 17A involved_in ISO (PMID:19144317) UniProt PMID:19144317 NCBI chrNW_004955411:5,896,435...5,899,911
Ensembl chrNW_004955411:5,896,702...5,900,962 		JBrowse link
G Il17f interleukin 17F involved_in ISO (PMID:19144317) UniProt PMID:19144317 NCBI chrNW_004955411:5,852,767...5,859,208
Ensembl chrNW_004955411:5,852,767...5,859,208 		JBrowse link
positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:15692051) MGI PMID:15692051 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
positive regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta involved_in ISO (PMID:29384235) ARUK-UCL PMID:29384235 NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947 		JBrowse link
G Mbl2 mannose binding lectin 2 ISO RGD PMID:9920905 RGD:4889148 NCBI chrNW_004955425:7,704,371...7,708,951
Ensembl chrNW_004955425:7,702,137...7,709,006 		JBrowse link
G Phb1 prohibitin 1 involved_in ISO (PMID:17070910) UniProt PMID:17070910 NCBI chrNW_004955451:12,110,290...12,119,870
Ensembl chrNW_004955451:12,110,290...12,120,124 		JBrowse link
positive regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:30548312) ARUK-UCL PMID:30548312 NCBI chrNW_004955437:7,780,886...7,785,597
Ensembl chrNW_004955437:7,780,679...7,785,697 		JBrowse link
positive regulation of humoral immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr7 C-C motif chemokine receptor 7 involved_in ISO (PMID:10520991) BHF-UCL PMID:10520991 NCBI chrNW_004955451:15,086,119...15,101,862
Ensembl chrNW_004955451:15,086,119...15,095,561 		JBrowse link
G LOC102023843 HLA class II histocompatibility antigen, DM alpha chain involved_in ISO (PMID:11714799) BHF-UCL PMID:11714799 NCBI chrNW_004955437:1,558,806...1,562,294
Ensembl chrNW_004955437:1,558,911...1,562,162 		JBrowse link
G Zp3 zona pellucida glycoprotein 3 involved_in ISO (PMID:19004505) UniProt PMID:19004505 NCBI chrNW_004955456:15,013,472...15,020,809 JBrowse link
G Zp4 zona pellucida glycoprotein 4 involved_in ISO (PMID:19004505) UniProt PMID:19004505 NCBI chrNW_004955492:2,599,579...2,606,837 JBrowse link
positive regulation of humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer2 Fc fragment of IgE receptor II acts_upstream_of_or_within ISO (PMID:8041705) MGI PMID:8041705 NCBI chrNW_004955563:1,587,471...1,596,707
Ensembl chrNW_004955563:1,587,396...1,596,063 		JBrowse link
G Hpx hemopexin acts_upstream_of_or_within ISO (PMID:18641331) MGI PMID:18641331 NCBI chrNW_004955414:22,158,654...22,169,133
Ensembl chrNW_004955414:22,156,819...22,169,631 		JBrowse link
G Lta lymphotoxin alpha acts_upstream_of_or_within ISO (PMID:9834074) MGI PMID:9834074 NCBI chrNW_004955437:114,216...116,003
Ensembl chrNW_004955437:114,640...115,529 		JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:15692051) MGI PMID:15692051 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (PMID:8566034) MGI PMID:8566034 NCBI chrNW_004955406:35,005,577...35,127,395
Ensembl chrNW_004955406:35,005,214...35,129,552 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO (PMID:9834074) MGI PMID:9834074 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700 		JBrowse link
regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Evpl envoplakin acts_upstream_of_or_within ISO (PMID:27427436) MGI PMID:27427436 NCBI chrNW_004955506:6,227,488...6,246,339
Ensembl chrNW_004955506:6,227,673...6,246,138 		JBrowse link
G Ivl involucrin acts_upstream_of_or_within ISO (PMID:27427436) MGI PMID:27427436 NCBI chrNW_004955592:522,730...525,728 JBrowse link
G Ppl periplakin acts_upstream_of_or_within ISO (PMID:27427436) MGI PMID:27427436 NCBI chrNW_004955442:12,581,918...12,627,407
Ensembl chrNW_004955442:12,581,879...12,626,516 		JBrowse link
regulation of antimicrobial humoral response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp2r3c protein phosphatase 2 regulatory subunit B''gamma acts_upstream_of_or_within ISO (PMID:16129705) MGI PMID:16129705 NCBI chrNW_004955409:25,920,973...25,943,985 JBrowse link
regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qbp complement C1q binding protein involved_in ISO (PMID:8195709) UniProt PMID:8195709 NCBI chrNW_004955467:10,788,142...10,792,272
Ensembl chrNW_004955467:10,788,277...10,792,449 		JBrowse link
G Cd55 CD55 molecule (Cromer blood group) acts_upstream_of_or_within ISO (PMID:25284781) MGI PMID:25284781 NCBI chrNW_004955406:42,773,368...42,796,205 JBrowse link
G Cd59 CD59 molecule (CD59 blood group) acts_upstream_of_or_within ISO (PMID:25284781) MGI PMID:25284781 NCBI chrNW_004955422:12,500,572...12,528,738 JBrowse link
G Cd5l CD5 molecule like acts_upstream_of_or_within ISO (PMID:25284781) MGI PMID:25284781 NCBI chrNW_004955468:9,670,958...9,690,331
Ensembl chrNW_004955468:9,667,514...9,689,150 		JBrowse link
G Phb2 prohibitin 2 NOT|involved_in ISO (PMID:17070910) UniProt PMID:17070910 NCBI chrNW_004955413:4,557,969...4,563,697
Ensembl chrNW_004955413:4,558,259...4,563,582 		JBrowse link
G Susd4 sushi domain containing 4 involved_in ISO (PMID:23482636) UniProt PMID:23482636 NCBI chrNW_004955520:1,444,618...1,523,214
Ensembl chrNW_004955520:1,444,618...1,523,260 		JBrowse link
regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd55 CD55 molecule (Cromer blood group) acts_upstream_of_or_within ISO (PMID:9892684) MGI PMID:9892684 NCBI chrNW_004955406:42,773,368...42,796,205 JBrowse link
regulation of humoral immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd37 CD37 molecule acts_upstream_of_or_within ISO (PMID:10891477), (PMID:20709950) MGI PMID:10891477 PMID:20709950 NCBI chrNW_004955559:1,465,937...1,471,249
Ensembl chrNW_004955559:1,465,937...1,471,249 		JBrowse link
G Spns2 SPNS lysolipid transporter 2, sphingosine-1-phosphate involved_in
acts_upstream_of_or_within		 ISO (PMID:34260944)
(PMID:22664872)		 UniProt
MGI		 PMID:22664872 PMID:34260944 NCBI chrNW_004955467:12,405,172...12,441,490
Ensembl chrNW_004955467:12,406,666...12,441,490 		JBrowse link
regulation of humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (PMID:9015183) MGI PMID:9015183 NCBI chrNW_004955406:35,005,577...35,127,395
Ensembl chrNW_004955406:35,005,214...35,129,552 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12619
    response to stimulus 6826
      immune response 1224
        humoral immune response 141
          antimicrobial humoral response + 73
          complement activation + 34
          hemolymph coagulation 0
          humoral immune response mediated by circulating immunoglobulin + 24
          negative regulation of humoral immune response + 13
          positive regulation of humoral immune response + 22
          regulation of humoral immune response + 44
paths to the root