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ONTOLOGY REPORT - ANNOTATIONS

Term:intracellular iron ion homeostasis
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Accession:GO:0006879 term browser browse the term
Definition:A homeostatic process involved in the maintenance of a steady state level of iron ions within a cell.
Synonyms:exact_synonym: cellular iron ion homeostasis
 broad_synonym: iron homeostasis
 xref: Reactome:R-HSA-917937 "Iron uptake and transport"


show annotations for term's descendants           Sort by:
intracellular iron ion homeostasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 4933416E14Rikl RIKEN cDNA 4933416E14 gene like involved_in IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr  X:12,341,075...12,371,179
Ensembl chr  X:12,369,695...12,371,607 		JBrowse link
G AABR07034928.1 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000002		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 Ensembl chr12:439,533...439,826 JBrowse link
G Abcb7 ATP binding cassette subfamily B member 7 involved_in
acts_upstream_of_or_within		 ISS
IEA
ISO
IBA
IDA		 GO_REF:0000024
GO_REF:0000107
(PMID:30765471)
MGI:3628654 (PMID:16424901)
GO_REF:0000033
PMID:31511561		 UniProt
Ensembl
RGD
GO_Central		 PMID:16424901 PMID:30765471 PMID:31511561 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:126781736 NCBI chr  X:73,361,296...73,502,464
Ensembl chr  X:69,295,552...69,436,858 		JBrowse link
G Aco1 aconitase 1 acts_upstream_of_or_within
involved_in		 IDA
ISO
IBA
IEA		 MGI:1928268|MGI:3029223 (PMID:14726953)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:14726953 PMID:15086359 GO_REF:0000033 GO_REF:0000107, RGD:1642737 NCBI chr 5:60,055,895...60,111,920
Ensembl chr 5:55,259,827...55,316,391 		JBrowse link
G Acvr2b activin A receptor type 2B involved_in ISO (PMID:31800957) RGD PMID:31800957 NCBI chr 8:128,016,589...128,056,193
Ensembl chr 8:119,138,812...119,170,458 		JBrowse link
G Alas2 5'-aminolevulinate synthase 2 acts_upstream_of_or_within ISO MGI:2180151 (PMID:10562540) RGD PMID:10562540 NCBI chr  X:22,890,650...22,914,046
Ensembl chr  X:19,463,171...19,486,519 		JBrowse link
G Atp13a2 ATPase cation transporting 13A2 involved_in ISO
IEA		 (PMID:26818499)
GO_REF:0000107		 RGD
Ensembl		 PMID:26818499 GO_REF:0000107 NCBI chr 5:158,575,727...158,595,157
Ensembl chr 5:153,292,751...153,312,139 		JBrowse link
G Atp6ap1 ATPase H+ transporting accessory protein 1 involved_in ISO
IEA
ISS		 (PMID:28296633)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:28296633 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:157,231,243...157,238,323
Ensembl chr  X:152,079,865...152,087,034 		JBrowse link
G Atp6v0a2 ATPase H+ transporting V0 subunit a2 involved_in ISO (PMID:28296633) RGD PMID:28296633 NCBI chr12:37,608,211...37,640,860
Ensembl chr12:31,822,733...32,007,069 		JBrowse link
G Atp6v0d1 ATPase H+ transporting V0 subunit D1 involved_in ISO
IEA		 (PMID:28296633)
GO_REF:0000107		 RGD
Ensembl		 PMID:28296633 GO_REF:0000107 NCBI chr19:50,313,268...50,357,248
Ensembl chr19:33,403,355...33,447,450 		JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A involved_in ISO
IEA		 (PMID:28296633)
GO_REF:0000107		 RGD
Ensembl		 PMID:28296633 GO_REF:0000107 NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694 		JBrowse link
G Atp6v1g1 ATPase H+ transporting V1 subunit G1 involved_in ISO
IEA		 (PMID:28296633)
GO_REF:0000107		 RGD
Ensembl		 PMID:28296633 GO_REF:0000107 NCBI chr 5:81,976,959...81,983,139
Ensembl chr 5:76,961,499...76,969,463 		JBrowse link
G B2m beta-2 microglobulin involved_in ISO
IEA		 (PMID:18353247)
GO_REF:0000107		 RGD
Ensembl		 PMID:18353247 GO_REF:0000107 NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:109,095,729...109,101,766 		JBrowse link
G Bmp6 bone morphogenetic protein 6 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:2136985 (PMID:21703414)
(PMID:19252488)
GO_REF:0000107		 RGD
Ensembl		 PMID:19252488 PMID:21703414 GO_REF:0000107 NCBI chr17:26,523,704...26,785,558
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Bola2 bolA family member 2 involved_in ISO
IEA
IBA		 (PMID:27519415)
GO_REF:0000002
GO_REF:0000033		 RGD
InterPro
GO_Central		 PMID:27519415 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:190,722,535...190,723,401
Ensembl chr 1:181,291,398...181,292,676 		JBrowse link
G Bola2l2 bolA family member 2 like 2 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000002		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr13:73,203,811...73,207,963 JBrowse link
G Ccdc115 coiled-coil domain containing 115 involved_in ISO (PMID:28296633) RGD PMID:28296633 NCBI chr 9:36,650,384...36,654,348
Ensembl chr 9:36,649,271...36,653,946 		JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:17,255,302...17,268,688
Ensembl chr20:17,255,151...17,284,924 		JBrowse link
G Cp ceruloplasmin involved_in TAS
ISS
ISO		 GO_REF:0000024
(PMID:14623105), (PMID:16150804), (PMID:29183916)		 UniProt
RGD		 PMID:14623105 PMID:16150804 PMID:29183916 PMID:12099680 GO_REF:0000024, RGD:727703 NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Cyb561 cytochrome b-561 involved_in ISO (PMID:14499595) RGD PMID:14499595 NCBI chr10:91,377,866...91,388,548
Ensembl chr10:90,878,054...90,884,787 		JBrowse link
G Cyb561a3 cytochrome b561 family, member A3 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:16911521)		 UniProt
Ensembl
RGD		 PMID:16911521 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:207,216,185...207,237,575
Ensembl chr 1:207,226,230...207,237,571 		JBrowse link
G Cybrd1 cytochrome b reductase 1 involved_in ISO
IEA		 (PMID:14499595)
GO_REF:0000107		 RGD
Ensembl		 PMID:14499595 GO_REF:0000107 NCBI chr 3:55,934,874...55,962,132
Ensembl chr 3:55,934,874...55,962,108 		JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 involved_in ISO (PMID:26818499) RGD PMID:26818499 NCBI chr19:69,765,276...69,804,681
Ensembl chr19:52,869,486...52,907,777 		JBrowse link
G ENSRNOG00000062366 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000002		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 Ensembl chr 3:153,272,475...153,273,513 JBrowse link
G ENSRNOG00000065765 involved_in IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 Ensembl chr 5:95,086,085...95,087,050 JBrowse link
G ENSRNOG00000067483 involved_in IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 Ensembl chr 1:23,638,268...23,638,719 JBrowse link
G Erfe erythroferrone involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:24880340)		 UniProt
Ensembl
RGD		 PMID:24880340 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:99,404,512...99,412,383
Ensembl chr 9:91,956,977...91,964,846 		JBrowse link
G Fbxl5 F-box and leucine-rich repeat protein 5 involved_in ISO
IEA		 (PMID:19762596), (PMID:19762597)
GO_REF:0000002		 RGD
InterPro		 PMID:19762596 PMID:19762597 GO_REF:0000002 NCBI chr14:71,517,452...71,559,850
Ensembl chr14:67,267,801...67,347,383 		JBrowse link
G Frrs1 ferric-chelate reductase 1 involved_in IBA
ISO		 GO_REF:0000033
(PMID:14499595)		 GO_Central
RGD		 PMID:14499595 GO_REF:0000033 NCBI chr 2:204,820,898...204,881,487
Ensembl chr 2:204,823,025...204,895,540 		JBrowse link
G Ftdc2 ferritin domain containing 2 involved_in IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr11:41,967,947...41,973,373
Ensembl chr11:41,968,796...41,972,351 		JBrowse link
G Fth1 ferritin heavy chain 1 involved_in IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr 1:216,052,037...216,054,325
Ensembl chr 1:206,627,103...206,725,424 		JBrowse link
G Fth1-ps5 ferritin heavy chain 1, pseudogene 5 involved_in IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr 3:136,914,889...136,915,757
Ensembl chr 3:136,914,906...136,915,776 		JBrowse link
G Fth1-ps5 ferritin heavy chain 1, pseudogene 5 involved_in IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 Ensembl chr 3:136,914,906...136,915,776 JBrowse link
G Fth1l1 ferritin heavy chain 1 like 1 involved_in IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr  X:13,684,960...13,685,803
Ensembl chr  X:13,685,097...13,685,657 		JBrowse link
G Fthl17a ferritin, heavy polypeptide-like 17, member A involved_in IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr  X:53,547,274...53,548,251
Ensembl chr  X:49,595,718...49,596,266 		JBrowse link
G Fthl17b ferritin, heavy polypeptide-like 17, member B involved_in IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr  X:13,841,394...13,842,228
Ensembl chr  X:13,841,394...13,842,228 		JBrowse link
G Fthl17cl1 ferritin, heavy polypeptide-like 17, member C like 1 involved_in IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr  X:13,802,420...13,803,501
Ensembl chr  X:13,802,417...13,803,251 		JBrowse link
G Fthl17fl ferritin, heavy polypeptide-like 17, member F like involved_in IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr  X:42,433,227...42,434,091
Ensembl chr  X:42,433,429...42,433,959 		JBrowse link
G Ftl1 ferritin light chain 1 involved_in TAS
IEA		 GO_REF:0000002
GO_REF:0000043		 InterPro
UniProt
RGD		 PMID:3584116 GO_REF:0000002 GO_REF:0000043, RGD:61589 NCBI chr 1:105,072,858...105,074,705
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725
Ensembl chr 2:95,936,387...95,939,725 		JBrowse link
G Ftl1l1 ferritin light chain 1 like 1 involved_in IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr  X:131,765,928...131,766,840
Ensembl chr  X:131,765,916...131,766,839 		JBrowse link
G Ftl1l2 ferritin light chain 1 like 2 involved_in IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr 6:73,242,612...73,243,527
Ensembl chr 6:73,242,608...73,253,291
Ensembl chr 2:73,242,608...73,253,291 		JBrowse link
G Ftl1l5 ferritin light chain 1 like 5 involved_in IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr 7:12,220,109...12,221,018
Ensembl chr 7:12,220,103...12,221,023
Ensembl chr 2:12,220,103...12,221,023 		JBrowse link
G Ftl1l6 ferritin light chain 1 like 6 involved_in IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr 2:51,392,265...51,393,293
Ensembl chr 2:51,392,298...51,393,071 		JBrowse link
G Ftl1l7 ferritin light chain 1 like 7 involved_in IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr 1:165,377,580...165,378,490
Ensembl chr 1:165,377,553...165,378,489
Ensembl chr 2:165,377,553...165,378,489 		JBrowse link
G Ftmt ferritin mitochondrial involved_in ISO
IEA		 (PMID:11323407), (PMID:18160053)
GO_REF:0000002
GO_REF:0000043
GO_REF:0000107		 RGD
InterPro
UniProt
Ensembl		 PMID:11323407 PMID:18160053 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 NCBI chr18:45,758,874...45,760,123
Ensembl chr18:45,758,874...45,760,123 		JBrowse link
G Fxn frataxin involved_in
acts_upstream_of_or_within		 NAS
IEA
ISO		 GO_REF:0000002
GO_REF:0000043
MGI:2177175|MGI:2177176 (PMID:9405681)
(PMID:18160053)		 InterPro
UniProt
RGD		 PMID:9405681 PMID:18160053 PMID:15247478 GO_REF:0000002 GO_REF:0000043, RGD:1304347 NCBI chr 1:231,300,457...231,323,989
Ensembl chr 1:221,872,420...221,897,540 		JBrowse link
G Glrx3 glutaredoxin 3 involved_in ISO
IEA
IBA		 (PMID:27519415)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:27519415 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:201,671,410...201,701,722
Ensembl chr 1:192,241,701...192,272,010 		JBrowse link
G Hamp hepcidin antimicrobial peptide involved_in IDA
IEA
ISO
IBA		 GO_REF:0000002
(PMID:11447267)
GO_REF:0000033
(PMID:15514116)
GO_REF:0000107		 InterPro
RGD
GO_Central
Ensembl		 PMID:11447267 PMID:15514116 PMID:14592944 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:1304454 NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Hephl1 hephaestin-like 1 involved_in ISO
IEA		 (PMID:31125343)
GO_REF:0000107		 RGD
Ensembl		 PMID:31125343 GO_REF:0000107 NCBI chr 8:11,896,768...11,965,282
Ensembl chr 8:11,898,532...11,965,267 		JBrowse link
G Hfe homeostatic iron regulator involved_in TAS
ISO		 (PMID:10085150), (PMID:18353247) RGD PMID:10085150 PMID:18353247 PMID:12927914 RGD:1304426 NCBI chr17:41,841,302...41,849,359
Ensembl chr17:41,413,451...41,421,502 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha acts_upstream_of_or_within ISO
IEA		 MGI:1857719 (PMID:16787915)
GO_REF:0000107		 RGD
Ensembl		 PMID:16787915 GO_REF:0000107 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hjv hemojuvelin BMP co-receptor involved_in IEA
ISO		 GO_REF:0000107
(PMID:25860887)		 Ensembl
RGD		 PMID:25860887 GO_REF:0000107 NCBI chr 2:186,754,801...186,758,708
Ensembl chr 2:184,065,970...184,069,850 		JBrowse link
G Hmox1 heme oxygenase 1 involved_in ISO
IEA		 (PMID:17915953), (PMID:22989377)
GO_REF:0000107		 RGD
Ensembl		 PMID:17915953 PMID:22989377 GO_REF:0000107 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hpx hemopexin involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:169,344,647...169,352,155
Ensembl chr 1:159,932,755...159,940,328 		JBrowse link
G Ireb2 iron responsive element binding protein 2 involved_in
acts_upstream_of_or_within		 ISS
IEA
IBA
ISO		 GO_REF:0000024
GO_REF:0000107
GO_REF:0000033
MGI:2181660|MGI:87879 (PMID:11175792), (PMID:14726953), (PMID:15831703)
(PMID:30915432)		 UniProt
Ensembl
GO_Central
RGD		 PMID:11175792 PMID:14726953 PMID:15831703 PMID:30915432 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:64,124,152...64,207,702
Ensembl chr 8:55,228,085...55,311,611 		JBrowse link
G Iscu iron-sulfur cluster assembly enzyme involved_in ISO
IEA
IBA		 (PMID:16517407), (PMID:23508953)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:16517407 PMID:23508953 GO_REF:0000033 GO_REF:0000107 NCBI chr12:42,852,305...42,858,150
Ensembl chr12:42,852,305...42,858,150 		JBrowse link
G LOC100360087 ferritin light chain 1-like involved_in IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr 5:146,322,749...146,323,666
Ensembl chr 5:146,322,756...146,323,666
Ensembl chr 5:146,322,756...146,323,666 		JBrowse link
G LOC100362384 ferritin light chain 1-like involved_in IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr13:83,117,280...83,118,226
Ensembl chr13:83,117,297...83,118,233
Ensembl chr 2:83,117,297...83,118,233 		JBrowse link
G LOC102549852 ferritin light chain 1-like involved_in IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr 1:143,810,386...143,811,096
Ensembl chr 1:143,810,583...143,810,987
Ensembl chr10:143,810,583...143,810,987 		JBrowse link
G LOC108352322 ferritin heavy chain-like involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr11:41,981,719...41,990,330
Ensembl chr11:41,987,207...41,995,209 		JBrowse link
G LOC120099305 ferritin heavy chain-like involved_in IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr  X:13,753,331...13,754,173
Ensembl chr  X:13,753,476...13,754,036 		JBrowse link
G LOC120102993 ferritin light chain 1-like involved_in IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr 5:144,647,550...144,648,460
Ensembl chr 5:144,647,541...144,648,477 		JBrowse link
G Mecr mitochondrial trans-2-enoyl-CoA reductase acts_upstream_of ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:37653044)		 UniProt
Ensembl
RGD		 PMID:37653044 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:144,029,684...144,056,373
Ensembl chr 5:144,029,731...144,055,863 		JBrowse link
G Meltf melanotransferrin NOT|acts_upstream_of_or_within ISO MGI:3691276 (PMID:16291590) RGD PMID:16291590 NCBI chr11:82,389,420...82,411,270
Ensembl chr11:68,884,446...68,906,300 		JBrowse link
G Mon1a MON1 homolog A, secretory trafficking associated acts_upstream_of_or_within ISO (PMID:17632513) RGD PMID:17632513 NCBI chr 8:108,574,272...108,593,163
Ensembl chr 8:108,574,388...108,593,156 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO
ISS		 (PMID:9924025)
GO_REF:0000024		 RGD
UniProt		 PMID:9924025 GO_REF:0000024 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Ncoa4 nuclear receptor coactivator 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25327288)
GO_REF:0000107
GO_REF:0000002		 RGD
Ensembl
InterPro		 PMID:25327288 GO_REF:0000002 GO_REF:0000107 NCBI chr16:7,395,502...7,415,846
Ensembl chr16:7,366,542...7,409,641
Ensembl chr16:7,366,542...7,409,641 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 involved_in ISO
IEA		 (PMID:18776082)
GO_REF:0000107		 RGD
Ensembl		 PMID:18776082 GO_REF:0000107 NCBI chr18:30,516,931...30,567,199
Ensembl chr18:30,250,613...30,322,311 		JBrowse link
G Neo1 neogenin 1 acts_upstream_of_or_within ISO
IEA		 MGI:3665445 (PMID:20065295)
GO_REF:0000107		 RGD
Ensembl		 PMID:20065295 GO_REF:0000107 NCBI chr 8:68,169,711...68,322,158
Ensembl chr 8:59,275,569...59,430,348 		JBrowse link
G Nubp1 NUBP iron-sulfur cluster assembly factor 1 involved_in ISO
IEA		 (PMID:18573874)
GO_REF:0000107		 RGD
Ensembl		 PMID:18573874 GO_REF:0000107 NCBI chr10:5,766,157...5,777,648 JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein involved_in IEA
ISO		 GO_REF:0000107
(PMID:22952941)		 Ensembl
RGD		 PMID:22952941 GO_REF:0000107 NCBI chr 1:153,468,982...153,550,086
Ensembl chr 1:144,056,721...144,137,557 		JBrowse link
G RGD1560203 similar to ferritin heavy polypeptide-like 17 involved_in IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr  X:32,402,662...32,403,192
Ensembl chr  X:32,402,662...32,403,192 		JBrowse link
G Scara5 scavenger receptor class A, member 5 involved_in ISO
IEA		 (PMID:19154717)
GO_REF:0000104
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:19154717 GO_REF:0000104 GO_REF:0000107 NCBI chr15:39,880,017...39,985,007
Ensembl chr15:39,880,035...39,983,373 		JBrowse link
G Sco1 synthesis of cytochrome C oxidase 1 acts_upstream_of_or_within ISO (PMID:36301669) RGD PMID:36301669 NCBI chr10:52,243,664...52,256,250
Ensembl chr10:51,744,656...51,757,237 		JBrowse link
G Slc11a1 solute carrier family 11 member 1 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:16510578)
GO_REF:0000107
MGI:2446573 (PMID:11903051), (PMID:18456389), (PMID:19321419)		 RGD
Ensembl		 PMID:11903051 PMID:16510578 PMID:18456389 PMID:19321419 GO_REF:0000107 NCBI chr 9:83,406,327...83,417,252
Ensembl chr 9:75,957,316...75,968,101 		JBrowse link
G Slc40a1 solute carrier family 40 member 1 involved_in ISO
IEA		 (PMID:12091367)
GO_REF:0000107		 RGD
Ensembl		 PMID:12091367 GO_REF:0000107 NCBI chr 9:55,525,457...55,633,463
Ensembl chr 9:48,033,526...48,051,481 		JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 acts_upstream_of_or_within ISO (PMID:35714613) RGD PMID:35714613 NCBI chr 1:163,371,410...163,419,412
Ensembl chr 1:153,959,293...154,007,353 		JBrowse link
G Smad1 SMAD family member 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:31800957)		 Ensembl
RGD		 PMID:31800957 GO_REF:0000107 NCBI chr19:45,417,430...45,477,962
Ensembl chr19:28,513,131...28,573,651 		JBrowse link
G Smad4 SMAD family member 4 involved_in IEA
ISO		 GO_REF:0000107
(PMID:16330325)		 Ensembl
RGD		 PMID:16330325 GO_REF:0000107 NCBI chr18:69,518,988...69,549,684
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Smad5 SMAD family member 5 involved_in IEA
ISO		 GO_REF:0000107
(PMID:31800957)		 Ensembl
RGD		 PMID:31800957 GO_REF:0000107 NCBI chr17:7,867,640...7,896,983
Ensembl chr17:7,864,720...7,891,634 		JBrowse link
G Smad9 SMAD family member 9 involved_in ISO (PMID:31800957) RGD PMID:31800957 NCBI chr 2:141,106,668...141,156,477
Ensembl chr 2:138,986,471...139,006,307 		JBrowse link
G Sod1 superoxide dismutase 1 involved_in
acts_upstream_of_or_within		 ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
MGI:1857872 (PMID:16377630)		 UniProt
Ensembl
RGD		 PMID:16377630 GO_REF:0000024 GO_REF:0000107 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Tf transferrin involved_in TAS
IEA
ISO		 GO_REF:0000002
UniProtKB:Q9UP52 (PMID:18353247)		 InterPro
RGD		 PMID:18353247 PMID:12608731 GO_REF:0000002, RGD:737676 NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:103,767,995...103,816,511 		JBrowse link
G Tfr2 transferrin receptor 2 involved_in ISO (PMID:18353247) RGD PMID:18353247 NCBI chr12:24,744,450...24,761,413
Ensembl chr12:19,107,673...19,124,591 		JBrowse link
G Tfrc transferrin receptor involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000104
GO_REF:0000107
MGI:1859944 (PMID:10192390)
GO_REF:0000033		 UniProt
Ensembl
RGD
GO_Central		 PMID:10192390 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 NCBI chr11:81,668,478...81,690,318
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Tmem199 transmembrane protein 199 involved_in ISO
IEA
ISS		 (PMID:28296633)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:28296633 GO_REF:0000024 GO_REF:0000107 NCBI chr10:63,900,543...63,905,115
Ensembl chr10:63,402,494...63,407,108 		JBrowse link
G Tmprss6 transmembrane serine protease 6 involved_in ISO
IEA		 (PMID:25860887)
GO_REF:0000107		 RGD
Ensembl		 PMID:25860887 GO_REF:0000107 NCBI chr 7:111,871,504...111,902,127
Ensembl chr 7:109,985,931...110,021,624 		JBrowse link
G Ttc7a tetratricopeptide repeat domain 7A acts_upstream_of_or_within ISO
IEA		 MGI:1856879 (PMID:15155459)
GO_REF:0000107		 RGD
Ensembl		 PMID:15155459 GO_REF:0000107 NCBI chr 6:7,159,285...7,261,826
Ensembl chr 6:7,159,061...7,261,892 		JBrowse link
cellular response to iron ion starvation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hfe homeostatic iron regulator IEP RGD PMID:16208485 RGD:1582698 NCBI chr17:41,841,302...41,849,359
Ensembl chr17:41,413,451...41,421,502 		JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 acts_upstream_of_or_within ISO (PMID:35714613) RGD PMID:35714613 NCBI chr 1:163,371,410...163,419,412
Ensembl chr 1:153,959,293...154,007,353 		JBrowse link
endocytic iron import into cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tfr2 transferrin receptor 2 involved_in ISO
IBA		 UniProtKB:P02787|UniProtKB:Q07891 (PMID:18353247)
GO_REF:0000033		 RGD
GO_Central		 PMID:18353247 GO_REF:0000033 NCBI chr12:24,744,450...24,761,413
Ensembl chr12:19,107,673...19,124,591 		JBrowse link
heme import into cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slco2b1 solute carrier organic anion transporter family, member 2b1 acts_upstream_of_or_within ISO (PMID:35714613) RGD PMID:35714613 NCBI chr 1:163,371,410...163,419,412
Ensembl chr 1:153,959,293...154,007,353 		JBrowse link
iron import into cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc11a2 solute carrier family 11 member 2 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:17109629)
GO_REF:0000107
MGI:1856400 (PMID:11739192)		 RGD
Ensembl		 PMID:11739192 PMID:17109629 GO_REF:0000107 NCBI chr 7:133,381,878...133,429,921
Ensembl chr 7:131,503,081...131,540,145 		JBrowse link
G Slc39a14 solute carrier family 39 member 14 involved_in ISO
IEA		 (PMID:20682781)
GO_REF:0000107		 RGD
Ensembl		 PMID:20682781 GO_REF:0000107 NCBI chr15:51,786,517...51,833,260
Ensembl chr15:45,376,917...45,423,524 		JBrowse link
G Steap3 STEAP3 metalloreductase acts_upstream_of_or_within ISO (PMID:16609065) RGD PMID:16609065 NCBI chr13:33,904,710...33,950,100
Ensembl chr13:31,351,954...31,396,519 		JBrowse link
G Steap4 STEAP4 metalloreductase acts_upstream_of_or_within ISO
IEA		 (PMID:16609065)
GO_REF:0000107		 RGD
Ensembl		 PMID:16609065 GO_REF:0000107 NCBI chr 4:27,032,096...27,054,769
Ensembl chr 4:26,054,671...26,099,859 		JBrowse link
iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc39a8 solute carrier family 39 member 8 involved_in ISO
IEA
IDA		 (PMID:22898811)
GO_REF:0000107
(PMID:22898811), (PMID:30015240)		 RGD
Ensembl		 PMID:22898811 PMID:30015240 PMID:22898811 GO_REF:0000107, RGD:15090842 NCBI chr 2:226,845,686...226,992,668
Ensembl chr 2:224,256,654...224,319,129 		JBrowse link
G Steap2 STEAP2 metalloreductase acts_upstream_of_or_within ISO
IEA		 (PMID:16609065)
GO_REF:0000107		 RGD
Ensembl		 PMID:16609065 GO_REF:0000107 NCBI chr 4:29,302,487...29,323,006
Ensembl chr 4:28,348,362...28,375,791 		JBrowse link
negative regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iscu iron-sulfur cluster assembly enzyme involved_in ISO
IEA		 (PMID:20436681)
GO_REF:0000107		 RGD
Ensembl		 PMID:20436681 GO_REF:0000107 NCBI chr12:42,852,305...42,858,150
Ensembl chr12:42,852,305...42,858,150 		JBrowse link
positive regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in ISO (PMID:29061364) RGD PMID:29061364 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Lcn2 lipocalin 2 IDA RGD PMID:25557118 RGD:126790477 NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Mir210 microRNA 210 involved_in ISO (PMID:20436681) RGD PMID:20436681 NCBI chr 1:205,755,923...205,756,032
Ensembl chr 1:196,326,337...196,326,454 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    homeostatic process 2032
      chemical homeostasis 1241
        inorganic ion homeostasis 605
          intracellular iron ion homeostasis 97
            cellular response to iron ion starvation + 2
            iron import into cell + 12
Path 2
Term Annotations click to browse term
  biological_process 20567
    homeostatic process 2032
      chemical homeostasis 1241
        monoatomic ion homeostasis 687
          intracellular monoatomic ion homeostasis 597
            intracellular monoatomic cation homeostasis 586
              intracellular iron ion homeostasis 97
                cellular response to iron ion starvation + 2
                iron import into cell + 12
paths to the root