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ONTOLOGY REPORT - ANNOTATIONS

Term:porphyrin-containing compound biosynthetic process
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Accession:GO:0006779 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.
Synonyms:related_synonym: porphyrin anabolism;   porphyrin biosynthesis;   porphyrin biosynthetic process;   porphyrin formation;   porphyrin synthesis


show annotations for term's descendants           Sort by:
porphyrin-containing compound biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb6 ATP binding cassette subfamily B member 6 involved_in ISO
IEA 		(PMID:17006453)
GO_REF:0000107 		RGD
Ensembl		 PMID:17006453 GO_REF:0000107 NCBI chr 9:84,117,222...84,125,939
Ensembl chr 9:76,668,554...76,676,924 		JBrowse link
G Alad aminolevulinate dehydratase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474 		JBrowse link
G Ank1 ankyrin 1 acts_upstream_of_or_within ISO MGI:1856298 (PMID:658175) RGD PMID:658175 NCBI chr16:68,876,294...69,054,963
Ensembl chr16:68,877,504...69,054,759 		JBrowse link
G Cpox coproporphyrinogen oxidase involved_in IEA GO_REF:0000002
GO_REF:0000043 		InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr11:41,936,585...41,946,568
Ensembl chr11:41,936,591...41,946,746 		JBrowse link
G Fech ferrochelatase acts_upstream_of_or_within
involved_in 		ISO
IEA 		MGI:2384729 (PMID:12149233)
GO_REF:0000107
GO_REF:0000043 		RGD
Ensembl
UniProt		 PMID:12149233 GO_REF:0000043 GO_REF:0000107 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348 		JBrowse link
G Hmbs hydroxymethylbilane synthase involved_in IDA
IEA 		uroporphyrin I
GO_REF:0000043
GO_REF:0000117
Urophorphyrin I
Uroporphyrinogen
Uroporphyrin I 		UniProt
RGD		 PMID:11786116 PMID:3963818 PMID:3702597 PMID:994723 PMID:6694518 More... GO_REF:0000043 GO_REF:0000117, RGD:26923962, RGD:4144803, RGD:4144820, RGD:25440497, RGD:25330343, RGD:25440495, RGD:25394584, RGD:25394583, RGD:26923963, RGD:2301707, RGD:4144783 NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957 		JBrowse link
G Ppox protoporphyrinogen oxidase involved_in IDA
IEA
ISO 		GO_REF:0000043
GO_REF:0000107
GO_REF:0000002
(PMID:7713909) 		UniProt
Ensembl
InterPro
RGD		 PMID:7713909 PMID:3663105 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107, RGD:1599180 NCBI chr13:83,697,661...83,701,998
Ensembl chr13:83,664,891...83,701,805 		JBrowse link
G Rsad1 radical S-adenosyl methionine domain containing 1 involved_in IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr10:79,485,253...79,499,616
Ensembl chr10:79,489,909...79,499,573 		JBrowse link
G Slc11a2 solute carrier family 11 member 2 acts_upstream_of_or_within ISO
IEA 		MGI:1856400 (PMID:658175)
GO_REF:0000107 		RGD
Ensembl		 PMID:658175 GO_REF:0000107 NCBI chr 7:133,381,878...133,429,921
Ensembl chr 7:131,503,081...131,540,145 		JBrowse link
G Spta1 spectrin, alpha, erythrocytic 1 acts_upstream_of_or_within ISO
IEA 		MGI:1856181|MGI:1856377 (PMID:658175)
GO_REF:0000107 		RGD
Ensembl		 PMID:658175 GO_REF:0000107 NCBI chr13:86,203,504...86,279,371
Ensembl chr13:86,203,504...86,279,371 		JBrowse link
G Sptb spectrin, beta, erythrocytic acts_upstream_of_or_within ISO MGI:1856378 (PMID:658175) RGD PMID:658175 NCBI chr 6:95,310,342...95,437,221
Ensembl chr 6:95,310,326...95,437,118 		JBrowse link
G Urod uroporphyrinogen decarboxylase involved_in IDA
IEA 		GO_REF:0000002
GO_REF:0000043 		InterPro
UniProt
RGD		 PMID:12381387 GO_REF:0000002 GO_REF:0000043, RGD:4144825 NCBI chr 5:130,464,695...130,468,783
Ensembl chr 5:130,455,217...130,468,808 		JBrowse link
G Uros uroporphyrinogen III synthase acts_upstream_of_or_within
involved_in 		ISO
IEA 		MGI:3620007 (PMID:7607680)
GO_REF:0000107
GO_REF:0000117 		RGD
Ensembl
UniProt		 PMID:7607680 GO_REF:0000107 GO_REF:0000117 MGI:3620006 NCBI chr 1:188,490,832...188,513,659
Ensembl chr 1:188,490,323...188,512,249 		JBrowse link
heme A biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alad aminolevulinate dehydratase involved_in ISO
IEA 		(PMID:14050799), (PMID:5393940)
GO_REF:0000107 		RGD
Ensembl		 PMID:5393940 PMID:14050799 GO_REF:0000107 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474 		JBrowse link
G Alas1 5'-aminolevulinate synthase 1 involved_in IEA
ISO 		GO_REF:0000107
MGI:4440831 (PMID:33307066) 		Ensembl
RGD		 PMID:33307066 GO_REF:0000107 NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917 		JBrowse link
G Cox10 cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 involved_in
acts_upstream_of_or_within 		ISO
IEA
IBA 		(PMID:12928484)
GO_REF:0000107
GO_REF:0000033
UniProtKB:Q12887 (PMID:12928484)
(PMID:16103131), (PMID:16782876) 		RGD
Ensembl
GO_Central		 PMID:12928484 PMID:16103131 PMID:16782876 GO_REF:0000033 GO_REF:0000107 NCBI chr10:48,630,993...48,742,805
Ensembl chr10:48,630,676...48,746,667 		JBrowse link
G Cox15 cytochrome c oxidase assembly homolog COX15 involved_in ISO
IEA
IBA 		UniProtKB:Q7KZN9-1 (PMID:12474143)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000033 		RGD
Ensembl
InterPro
GO_Central		 PMID:12474143 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:242,605,588...242,622,279
Ensembl chr 1:242,605,588...242,622,261 		JBrowse link
G Cpox coproporphyrinogen oxidase involved_in IEA
ISO 		GO_REF:0000107
(PMID:8407975) 		Ensembl
RGD		 PMID:8407975 GO_REF:0000107 NCBI chr11:41,936,585...41,946,568
Ensembl chr11:41,936,591...41,946,746 		JBrowse link
G Fech ferrochelatase involved_in ISO
IEA 		MGI:1858114 (PMID:15677551)
GO_REF:0000107 		RGD
Ensembl		 PMID:15677551 GO_REF:0000107 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348 		JBrowse link
G Hmbs hydroxymethylbilane synthase involved_in IEA
ISO 		GO_REF:0000107
MGI:2182340 (PMID:8563760) 		Ensembl
RGD		 PMID:8563760 GO_REF:0000107 NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957 		JBrowse link
G Ppox protoporphyrinogen oxidase involved_in ISO
IEA 		(PMID:3346226)
GO_REF:0000107 		RGD
Ensembl		 PMID:3346226 GO_REF:0000107 NCBI chr13:83,697,661...83,701,998
Ensembl chr13:83,664,891...83,701,805 		JBrowse link
G Urod uroporphyrinogen decarboxylase involved_in IEA
ISO 		GO_REF:0000107
MGI:2687172 (PMID:17360334) 		Ensembl
RGD		 PMID:17360334 GO_REF:0000107 NCBI chr 5:130,464,695...130,468,783
Ensembl chr 5:130,455,217...130,468,808 		JBrowse link
G Uros uroporphyrinogen III synthase involved_in ISO
IEA 		MGI:3776884 (PMID:16532394)
GO_REF:0000107 		RGD
Ensembl		 PMID:16532394 GO_REF:0000107 NCBI chr 1:188,490,832...188,513,659
Ensembl chr 1:188,490,323...188,512,249 		JBrowse link
heme B biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb6 ATP binding cassette subfamily B member 6 NOT|involved_in ISO (PMID:22655043) RGD PMID:22655043 NCBI chr 9:84,117,222...84,125,939
Ensembl chr 9:76,668,554...76,676,924 		JBrowse link
G Alad aminolevulinate dehydratase involved_in ISO
IEA 		(PMID:14050799), (PMID:5393940)
(PMID:11032836)
GO_REF:0000107 		RGD
Ensembl		 PMID:5393940 PMID:11032836 PMID:14050799 GO_REF:0000107 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474 		JBrowse link
G Alas1 5'-aminolevulinate synthase 1 involved_in IEA
ISO 		GO_REF:0000107
MGI:4440831 (PMID:33307066) 		Ensembl
RGD		 PMID:33307066 GO_REF:0000107 NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917 		JBrowse link
G Alas2 5'-aminolevulinate synthase 2 involved_in ISO (PMID:2050125) RGD PMID:2050125 NCBI chr  X:19,463,146...19,486,526
Ensembl chr  X:19,463,171...19,486,519 		JBrowse link
G Cpox coproporphyrinogen oxidase involved_in IEA
ISO 		GO_REF:0000107
(PMID:7987309)
(PMID:8407975) 		Ensembl
RGD		 PMID:7987309 PMID:8407975 GO_REF:0000107 NCBI chr11:41,936,585...41,946,568
Ensembl chr11:41,936,591...41,946,746 		JBrowse link
G Fech ferrochelatase involved_in ISO
IEA 		MGI:1858114 (PMID:15677551)
(PMID:27599036)
GO_REF:0000107 		RGD
Ensembl		 PMID:15677551 PMID:27599036 GO_REF:0000107 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348 		JBrowse link
G Hmbs hydroxymethylbilane synthase involved_in IEA
ISO 		GO_REF:0000107
(PMID:18004775)
MGI:2182340 (PMID:8563760) 		Ensembl
RGD		 PMID:8563760 PMID:18004775 GO_REF:0000107 NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957 		JBrowse link
G Ppox protoporphyrinogen oxidase involved_in ISO
IEA 		(PMID:3346226)
(PMID:7713909)
GO_REF:0000107 		RGD
Ensembl		 PMID:3346226 PMID:7713909 GO_REF:0000107 NCBI chr13:83,697,661...83,701,998
Ensembl chr13:83,664,891...83,701,805 		JBrowse link
G Urod uroporphyrinogen decarboxylase involved_in IEA
ISO 		GO_REF:0000107
(PMID:11069625)
MGI:2687172 (PMID:17360334) 		Ensembl
RGD		 PMID:11069625 PMID:17360334 GO_REF:0000107 NCBI chr 5:130,464,695...130,468,783
Ensembl chr 5:130,455,217...130,468,808 		JBrowse link
G Uros uroporphyrinogen III synthase involved_in ISO
IEA 		MGI:3776884 (PMID:16532394)
(PMID:18004775)
GO_REF:0000107 		RGD
Ensembl		 PMID:16532394 PMID:18004775 GO_REF:0000107 NCBI chr 1:188,490,832...188,513,659
Ensembl chr 1:188,490,323...188,512,249 		JBrowse link
heme biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb10 ATP binding cassette subfamily B member 10 involved_in ISO
IEA 		(PMID:24421385)
GO_REF:0000107 		RGD
Ensembl		 PMID:24421385 GO_REF:0000107 NCBI chr19:68,850,108...68,881,689
Ensembl chr19:51,952,681...51,982,753 		JBrowse link
G Alad aminolevulinate dehydratase acts_upstream_of_or_within
involved_in 		IDA
IEA
ISO
ISS
IBA 		GO_REF:0000107
GO_REF:0000043
(PMID:14050799), (PMID:4959158), (PMID:4981581)
GO_REF:0000024
(PMID:11032836)
GO_REF:0000033 		Ensembl
UniProt
RGD
GO_Central		 PMID:4959158 PMID:4981581 PMID:11032836 PMID:14050799 PMID:1764448 GO_REF:0000024 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107, RGD:1599020 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474 		JBrowse link
G Alas1 5'-aminolevulinate synthase 1 involved_in IBA
IEA 		GO_REF:0000033
GO_REF:0000043 		GO_Central
UniProt		 GO_REF:0000033 GO_REF:0000043 NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917 		JBrowse link
G Alas2 5'-aminolevulinate synthase 2 involved_in ISS
IEA
ISO
IBA 		GO_REF:0000024
GO_REF:0000043
(PMID:9446639)
GO_REF:0000033 		UniProt
RGD
GO_Central		 PMID:9446639 GO_REF:0000024 GO_REF:0000033 GO_REF:0000043 NCBI chr  X:19,463,146...19,486,526
Ensembl chr  X:19,463,171...19,486,519 		JBrowse link
G Atp5if1 ATP synthase inhibitory factor subunit 1 involved_in ISS
IBA
ISO 		GO_REF:0000024
GO_REF:0000033
(PMID:23135403) 		UniProt
GO_Central
RGD		 PMID:23135403 GO_REF:0000024 GO_REF:0000033 NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668 		JBrowse link
G Cox10 cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 involved_in IEA GO_REF:0000002
GO_REF:0000043 		InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr10:48,630,993...48,742,805
Ensembl chr10:48,630,676...48,746,667 		JBrowse link
G Cox15 cytochrome c oxidase assembly homolog COX15 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:242,605,588...242,622,279
Ensembl chr 1:242,605,588...242,622,261 		JBrowse link
G Cpox coproporphyrinogen oxidase involved_in
acts_upstream_of_or_within 		IDA
IEA
ISO 		GO_REF:0000043
GO_REF:0000117
GO_REF:0000107
(PMID:8407975) 		UniProt
Ensembl
RGD		 PMID:8407975 PMID:3955059 GO_REF:0000043 GO_REF:0000107 GO_REF:0000117, RGD:1600961 NCBI chr11:41,936,585...41,946,568
Ensembl chr11:41,936,591...41,946,746 		JBrowse link
G Fech ferrochelatase involved_in
acts_upstream_of_or_within 		IDA
ISO
IEA
IBA 		(PMID:15123683), (PMID:27599036)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000104
GO_REF:0000043
GO_REF:0000033
MGI:1858114|MGI:2384729 (PMID:15496139), (PMID:16306232), (PMID:16503645), (PMID:8611576), (PMID:9989256) 		RGD
Ensembl
InterPro
UniProt
GO_Central		 PMID:8611576 PMID:9989256 PMID:15123683 PMID:15496139 PMID:16306232 More... GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107, RGD:1600961 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348 		JBrowse link
G Fxn frataxin involved_in IEA
ISO 		GO_REF:0000043
(PMID:15123683) 		UniProt
RGD		 PMID:15123683 GO_REF:0000043 NCBI chr 1:221,874,007...221,897,543
Ensembl chr 1:221,872,420...221,897,540 		JBrowse link
G Hmbs hydroxymethylbilane synthase involved_in ISO
IEA
IBA 		(PMID:18936296)
GO_REF:0000107
GO_REF:0000043
GO_REF:0000033 		RGD
Ensembl
UniProt
GO_Central		 PMID:18936296 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107 NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957 		JBrowse link
G Hnf1a HNF1 homeobox A acts_upstream_of_or_within ISO
IEA 		MGI:2384429 (PMID:10617683)
GO_REF:0000107 		RGD
Ensembl		 PMID:10617683 GO_REF:0000107 NCBI chr12:47,299,171...47,333,457
Ensembl chr12:41,645,587...41,672,104 		JBrowse link
G Pgrmc1 progesterone receptor membrane component 1 involved_in ISO
IEA
ISS 		(PMID:27599036)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:27599036 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:115,832,865...115,841,060
Ensembl chr  X:115,832,884...115,888,682 		JBrowse link
G Ppox protoporphyrinogen oxidase involved_in
acts_upstream_of_or_within 		IDA
IEA
ISO
IBA 		GO_REF:0000107
GO_REF:0000043
(PMID:3346226)
GO_REF:0000033
(PMID:7713909) 		Ensembl
UniProt
RGD
GO_Central		 PMID:3346226 PMID:7713909 PMID:3955059 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107, RGD:1600961 NCBI chr13:83,697,661...83,701,998
Ensembl chr13:83,664,891...83,701,805 		JBrowse link
G Slc11a2 solute carrier family 11 member 2 acts_upstream_of_or_within ISO
IEA 		MGI:1856400 (PMID:11739192)
GO_REF:0000107 		RGD
Ensembl		 PMID:11739192 GO_REF:0000107 NCBI chr 7:133,381,878...133,429,921
Ensembl chr 7:131,503,081...131,540,145 		JBrowse link
G Slc25a39 solute carrier family 25, member 39 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:87,362,494...87,367,358
Ensembl chr10:87,362,490...87,367,260 		JBrowse link
G Tmem14c transmembrane protein 14C involved_in
acts_upstream_of_or_within 		IEA
ISO 		GO_REF:0000043
MGI:4351741 (PMID:25157825) 		UniProt
RGD		 PMID:25157825 GO_REF:0000043 NCBI chr17:23,733,769...23,739,906
Ensembl chr17:23,733,894...23,753,320 		JBrowse link
G Tmem14cl1 transmembrane protein 14C like 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr13:100,656,576...100,657,086
Ensembl chr13:100,656,593...100,657,445 		JBrowse link
G Urod uroporphyrinogen decarboxylase acts_upstream_of_or_within
involved_in 		NAS
IEA
ISO
IBA
IC 		GO_REF:0000107
GO_REF:0000043
MGI:2687172 (PMID:17360334)
GO_REF:0000033 		Ensembl
UniProt
RGD
GO_Central		 PMID:17360334 PMID:3658690 PMID:15736160 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107, RGD:70052, RGD:2301379 NCBI chr 5:130,464,695...130,468,783
Ensembl chr 5:130,455,217...130,468,808 		JBrowse link
G Uros uroporphyrinogen III synthase involved_in ISO
IEA 		(PMID:3805019)
GO_REF:0000107 		RGD
Ensembl		 PMID:3805019 GO_REF:0000107 NCBI chr 1:188,490,832...188,513,659
Ensembl chr 1:188,490,323...188,512,249 		JBrowse link
heme O biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alad aminolevulinate dehydratase involved_in ISO
IEA 		(PMID:14050799), (PMID:5393940)
GO_REF:0000107 		RGD
Ensembl		 PMID:5393940 PMID:14050799 GO_REF:0000107 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474 		JBrowse link
G Alas1 5'-aminolevulinate synthase 1 involved_in IEA
ISO 		GO_REF:0000107
MGI:4440831 (PMID:33307066) 		Ensembl
RGD		 PMID:33307066 GO_REF:0000107 NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917 		JBrowse link
G Cox10 cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 involved_in ISO
IEA 		UniProtKB:Q12887 (PMID:12928484)
GO_REF:0000107 		RGD
Ensembl		 PMID:12928484 GO_REF:0000107 NCBI chr10:48,630,993...48,742,805
Ensembl chr10:48,630,676...48,746,667 		JBrowse link
G Cpox coproporphyrinogen oxidase involved_in IEA
ISO 		GO_REF:0000107
(PMID:8407975) 		Ensembl
RGD		 PMID:8407975 GO_REF:0000107 NCBI chr11:41,936,585...41,946,568
Ensembl chr11:41,936,591...41,946,746 		JBrowse link
G Fech ferrochelatase involved_in ISO
IEA 		MGI:1858114 (PMID:15677551)
GO_REF:0000107 		RGD
Ensembl		 PMID:15677551 GO_REF:0000107 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348 		JBrowse link
G Hmbs hydroxymethylbilane synthase involved_in IEA
ISO 		GO_REF:0000107
MGI:2182340 (PMID:8563760) 		Ensembl
RGD		 PMID:8563760 GO_REF:0000107 NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957 		JBrowse link
G Ppox protoporphyrinogen oxidase involved_in ISO
IEA 		(PMID:3346226)
GO_REF:0000107 		RGD
Ensembl		 PMID:3346226 GO_REF:0000107 NCBI chr13:83,697,661...83,701,998
Ensembl chr13:83,664,891...83,701,805 		JBrowse link
G Urod uroporphyrinogen decarboxylase involved_in IEA
ISO 		GO_REF:0000107
MGI:2687172 (PMID:17360334) 		Ensembl
RGD		 PMID:17360334 GO_REF:0000107 NCBI chr 5:130,464,695...130,468,783
Ensembl chr 5:130,455,217...130,468,808 		JBrowse link
G Uros uroporphyrinogen III synthase involved_in ISO
IEA 		MGI:3776884 (PMID:16532394)
GO_REF:0000107 		RGD
Ensembl		 PMID:16532394 GO_REF:0000107 NCBI chr 1:188,490,832...188,513,659
Ensembl chr 1:188,490,323...188,512,249 		JBrowse link
positive regulation of heme biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb7 ATP binding cassette subfamily B member 7 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:30765471) 		UniProt
Ensembl
RGD		 PMID:30765471 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:73,361,296...73,502,464
Ensembl chr  X:69,295,552...69,436,858 		JBrowse link
G Slc6a9 solute carrier family 6 member 9 involved_in ISO
IEA 		(PMID:28495915)
GO_REF:0000107 		RGD
Ensembl		 PMID:28495915 GO_REF:0000107 NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728 		JBrowse link
protoporphyrinogen IX biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alad aminolevulinate dehydratase involved_in IEA
ISO 		GO_REF:0000041
(PMID:11032836)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:11032836 GO_REF:0000041 GO_REF:0000107 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474 		JBrowse link
G Alas1 5'-aminolevulinate synthase 1 involved_in IEA GO_REF:0000041
GO_REF:0000104 		UniProt GO_REF:0000041 GO_REF:0000104 NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917 		JBrowse link
G Alas2 5'-aminolevulinate synthase 2 involved_in IEA
ISO 		GO_REF:0000041
(PMID:32499479)
GO_REF:0000104 		UniProt
RGD		 PMID:32499479 GO_REF:0000041 GO_REF:0000104 NCBI chr  X:19,463,146...19,486,526
Ensembl chr  X:19,463,171...19,486,519 		JBrowse link
G Cpox coproporphyrinogen oxidase involved_in IDA
ISO
IEA
IBA 		(PMID:7987309)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000041 		RGD
Ensembl
GO_Central
UniProt		 PMID:7987309 PMID:3814086 GO_REF:0000033 GO_REF:0000041 GO_REF:0000107, RGD:4145128 NCBI chr11:41,936,585...41,946,568
Ensembl chr11:41,936,591...41,946,746 		JBrowse link
G Hmbs hydroxymethylbilane synthase involved_in IEA
ISO 		GO_REF:0000041
(PMID:18004775)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:18004775 GO_REF:0000041 GO_REF:0000107 NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957 		JBrowse link
G Ireb2 iron responsive element binding protein 2 acts_upstream_of_or_within ISO
IEA 		MGI:2181660 (PMID:15831703)
GO_REF:0000107 		RGD
Ensembl		 PMID:15831703 GO_REF:0000107 NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611 		JBrowse link
G Ppox protoporphyrinogen oxidase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr13:83,697,661...83,701,998
Ensembl chr13:83,664,891...83,701,805 		JBrowse link
G Urod uroporphyrinogen decarboxylase involved_in IEA
ISO 		GO_REF:0000041
(PMID:11069625)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:11069625 GO_REF:0000041 GO_REF:0000107 NCBI chr 5:130,464,695...130,468,783
Ensembl chr 5:130,455,217...130,468,808 		JBrowse link
G Uros uroporphyrinogen III synthase involved_in IEA
ISO 		GO_REF:0000041
(PMID:18004775)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:18004775 GO_REF:0000041 GO_REF:0000107 NCBI chr 1:188,490,832...188,513,659
Ensembl chr 1:188,490,323...188,512,249 		JBrowse link
regulation of heme biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Srrd SRR1 domain containing involved_in ISO (PMID:28802827) RGD PMID:28802827 NCBI chr12:44,294,675...44,300,287
Ensembl chr12:44,294,271...44,300,287 		JBrowse link
G Tmem14a transmembrane protein 14A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:23,640,594...23,652,379
Ensembl chr 9:23,733,039...23,734,463
Ensembl chr 9:23,733,039...23,734,463 		JBrowse link
G Tmem14c transmembrane protein 14C involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:23,733,769...23,739,906
Ensembl chr17:23,733,894...23,753,320 		JBrowse link
G Tmem14cl1 transmembrane protein 14C like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:100,656,576...100,657,086
Ensembl chr13:100,656,593...100,657,445 		JBrowse link
uroporphyrinogen III biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Uros uroporphyrinogen III synthase involved_in IDA
IEA
IBA
ISO 		GO_REF:0000002
GO_REF:0000107
GO_REF:0000033
(PMID:18004775), (PMID:3174619), (PMID:3805019) 		InterPro
Ensembl
GO_Central
RGD		 PMID:3174619 PMID:3805019 PMID:18004775 PMID:17763925 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:4144811 NCBI chr 1:188,490,832...188,513,659
Ensembl chr 1:188,490,323...188,512,249 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        tetrapyrrole metabolic process 54
          porphyrin-containing compound metabolic process 44
            porphyrin-containing compound biosynthetic process 30
              chlorophyll biosynthetic process + 0
              heme biosynthetic process + 26
              protoporphyrinogen IX biosynthetic process + 9
              succinyl-CoA pathway 0
              uroporphyrinogen III biosynthetic process + 1
paths to the root