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ONTOLOGY REPORT - ANNOTATIONS

Term:NADPH regeneration
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Accession:GO:0006740 term browser browse the term
Definition:A metabolic process that generates a pool of NADPH by the reduction of NADP+.
Synonyms:exact_synonym: reduced NADP regeneration;   reduced nicotinamide adenine dinucleotide phosphate regeneration
 xref: Reactome:R-HSA-389542 "NADPH regeneration"


show annotations for term's descendants           Sort by:
NADPH regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:25550467) 		Ensembl
RGD		 PMID:25550467 GO_REF:0000107 NCBI chr 5:60,055,895...60,111,920
Ensembl chr 5:60,055,866...60,112,600 		JBrowse link
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 involved_in ISO
IEA
IDA 		(PMID:19933275)
GO_REF:0000107
PMID:1848231 		RGD
Ensembl		 PMID:19933275 PMID:1848231 GO_REF:0000107, RGD:632027 NCBI chr 4:124,617,182...124,663,674
Ensembl chr 4:124,617,217...124,664,704 		JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 involved_in ISO
IEA 		(PMID:21238436)
(PMID:33168096)
GO_REF:0000107 		RGD
Ensembl		 PMID:21238436 PMID:33168096 GO_REF:0000107 NCBI chr 7:22,141,872...22,193,403
Ensembl chr 7:22,141,842...22,193,398 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase involved_in IEA
ISO 		GO_REF:0000107
(PMID:21527585) 		Ensembl
RGD		 PMID:21527585 GO_REF:0000107 NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:157,352,373...157,372,144 		JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:21527585) 		Ensembl
RGD		 PMID:21527585 GO_REF:0000107 NCBI chr 9:74,027,887...74,057,442
Ensembl chr 9:74,027,892...74,049,555 		JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase involved_in IMP
IBA 		GO_REF:0000033 GO_Central
RGD		 PMID:22198343 GO_REF:0000033, RGD:13513982 NCBI chr 2:53,144,157...53,237,857
Ensembl chr 2:53,144,160...53,237,310 		JBrowse link
G Pgd phosphogluconate dehydrogenase involved_in IEA
ISO 		GO_REF:0000107
(PMID:21527585) 		Ensembl
RGD		 PMID:21527585 GO_REF:0000107 NCBI chr 5:164,865,830...164,882,029
Ensembl chr 5:164,865,830...164,882,029 		JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldob aldolase, fructose-bisphosphate B involved_in IEA
ISO 		GO_REF:0000107
(PMID:35122041) 		Ensembl
RGD		 PMID:35122041 GO_REF:0000107 NCBI chr 5:68,684,541...68,697,582
Ensembl chr 5:68,684,542...68,716,740 		JBrowse link
G Tp53 tumor protein p53 involved_in ISO
IEA 		(PMID:21336310)
GO_REF:0000107 		RGD
Ensembl		 PMID:21336310 GO_REF:0000107 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acacb acetyl-CoA carboxylase beta IMP RGD PMID:31709908 RGD:329901803 NCBI chr12:48,026,394...48,138,214
Ensembl chr12:48,026,394...48,138,214 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase involved_in IDA
IEA
ISO 		GO_REF:0000041
GO_REF:0000107
GO_REF:0000117
(PMID:2297768) 		UniProt
Ensembl
RGD		 PMID:2297768 PMID:2843500 GO_REF:0000041 GO_REF:0000107 GO_REF:0000117, RGD:1599574 NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:157,352,373...157,372,144 		JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) involved_in
acts_upstream_of_or_within 		IEA
ISO 		GO_REF:0000117
(PMID:12831846)
GO_REF:0000107
GO_REF:0000041
GO_REF:0000002 		UniProt
RGD
Ensembl
InterPro		 PMID:12831846 GO_REF:0000002 GO_REF:0000041 GO_REF:0000107 GO_REF:0000117 NCBI chr 5:165,717,456...165,753,158
Ensembl chr 5:165,721,654...165,753,125 		JBrowse link
G Pgd phosphogluconate dehydrogenase involved_in IDA
IEA
ISS 		GO_REF:0000117
GO_REF:0000002
GO_REF:0000043
GO_REF:0000041
GO_REF:0000024 		UniProt
InterPro
RGD		 PMID:2843500 GO_REF:0000002 GO_REF:0000024 GO_REF:0000041 GO_REF:0000043 GO_REF:0000117, RGD:1599574 NCBI chr 5:164,865,830...164,882,029
Ensembl chr 5:164,865,830...164,882,029 		JBrowse link
G Pgls 6-phosphogluconolactonase involved_in ISO
IEA 		(PMID:10518023)
GO_REF:0000117
GO_REF:0000002
GO_REF:0000107
GO_REF:0000041 		RGD
UniProt
InterPro
Ensembl		 PMID:10518023 GO_REF:0000002 GO_REF:0000041 GO_REF:0000107 GO_REF:0000117 NCBI chr16:18,334,299...18,339,785
Ensembl chr16:18,334,299...18,339,785 		JBrowse link
G Prps1 phosphoribosyl pyrophosphate synthetase 1 involved_in ISO (PMID:24855946) RGD PMID:24855946 NCBI chr  X:108,920,663...108,942,713
Ensembl chr  X:108,920,651...108,942,711 		JBrowse link
G Prps2 phosphoribosyl pyrophosphate synthetase 2 involved_in IEA
ISO 		GO_REF:0000107
(PMID:24855946) 		Ensembl
RGD		 PMID:24855946 GO_REF:0000107 NCBI chr  X:30,592,845...30,630,127
Ensembl chr  X:30,593,019...30,630,126 		JBrowse link
G Rbks ribokinase involved_in IEA
ISO 		GO_REF:0000107
(PMID:13405914)
GO_REF:0000117 		Ensembl
RGD
UniProt		 PMID:13405914 GO_REF:0000107 GO_REF:0000117 NCBI chr 6:30,467,724...30,544,284
Ensembl chr 6:30,467,726...30,544,294 		JBrowse link
G Rpe ribulose-5-phosphate-3-epimerase involved_in IDA
ISO
IEA 		(PMID:5360673)
GO_REF:0000117
GO_REF:0000107
GO_REF:0000002
(PMID:20923965) 		RGD
UniProt
Ensembl
InterPro		 PMID:5360673 PMID:20923965 PMID:2843500 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117, RGD:1599574 NCBI chr 9:75,640,867...75,661,009
Ensembl chr 9:75,640,982...75,661,643 		JBrowse link
G Rpia ribose 5-phosphate isomerase A involved_in IDA
ISO
IEA 		(PMID:5360673)
GO_REF:0000117
GO_REF:0000107
GO_REF:0000041 		RGD
UniProt
Ensembl		 PMID:5360673 PMID:2843500 GO_REF:0000041 GO_REF:0000107 GO_REF:0000117, RGD:1599574 NCBI chr 4:104,282,081...104,307,732
Ensembl chr 4:104,282,081...104,307,718 		JBrowse link
G Shpk sedoheptulokinase involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr10:58,316,065...58,340,489
Ensembl chr10:58,316,111...58,340,490 		JBrowse link
G Taldo1 transaldolase 1 involved_in IDA
ISO
IEA 		(PMID:13405914), (PMID:19436114), (PMID:5360673)
GO_REF:0000117
GO_REF:0000002
GO_REF:0000107
GO_REF:0000043
GO_REF:0000041 		RGD
UniProt
InterPro
Ensembl		 PMID:5360673 PMID:13405914 PMID:19436114 PMID:2843500 GO_REF:0000002 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 GO_REF:0000117, RGD:1599574 NCBI chr 1:205,923,196...205,933,526
Ensembl chr 1:205,923,165...205,933,535 		JBrowse link
G Tkt transketolase involved_in IDA
ISO 		(PMID:13405914), (PMID:5360673)
(PMID:20667822) 		RGD PMID:5360673 PMID:13405914 PMID:20667822 PMID:2843500 RGD:1599574 NCBI chr16:5,729,381...5,755,170
Ensembl chr16:5,729,991...5,756,431 		JBrowse link
pentose-phosphate shunt, non-oxidative branch term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpe ribulose-5-phosphate-3-epimerase involved_in IDA
IBA 		GO_REF:0000033 GO_Central
RGD		 PMID:3079759 GO_REF:0000033, RGD:1641816 NCBI chr 9:75,640,867...75,661,009
Ensembl chr 9:75,640,982...75,661,643 		JBrowse link
G Rpia ribose 5-phosphate isomerase A involved_in IDA
IEA
IBA 		GO_REF:0000002
GO_REF:0000033 		InterPro
GO_Central
RGD		 PMID:3079759 GO_REF:0000002 GO_REF:0000033, RGD:1641816 NCBI chr 4:104,282,081...104,307,732
Ensembl chr 4:104,282,081...104,307,718 		JBrowse link
G Shpk sedoheptulokinase involved_in IEA
ISO 		GO_REF:0000107
(PMID:22682222) 		Ensembl
RGD		 PMID:22682222 GO_REF:0000107 NCBI chr10:58,316,065...58,340,489
Ensembl chr10:58,316,111...58,340,490 		JBrowse link
G Taldo1 transaldolase 1 involved_in IDA
IEA
IBA
ISO 		GO_REF:0000107
GO_REF:0000033
(PMID:18498245) 		Ensembl
GO_Central
RGD		 PMID:18498245 PMID:8477719 PMID:3079759 GO_REF:0000033 GO_REF:0000107, RGD:1641803, RGD:1641816 NCBI chr 1:205,923,196...205,933,526
Ensembl chr 1:205,923,165...205,933,535 		JBrowse link
G Tkt transketolase involved_in IDA
ISO
IEA
IBA 		(PMID:32295803)
GO_REF:0000117
GO_REF:0000033 		RGD
UniProt
GO_Central		 PMID:32295803 PMID:16116031 PMID:3079759 GO_REF:0000033 GO_REF:0000117, RGD:1580394, RGD:1641816 NCBI chr16:5,729,381...5,755,170
Ensembl chr16:5,729,991...5,756,431 		JBrowse link
G Tktl2 transketolase-like 2 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr16:27,969,009...27,976,353
Ensembl chr16:27,968,871...27,976,442 		JBrowse link
pentose-phosphate shunt, oxidative branch term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase involved_in IMP
ISO
IEA
IBA 		MGI:2182739 (PMID:12466018), (PMID:22829586)
GO_REF:0000107
GO_REF:0000033
(PMID:2420826) 		RGD
Ensembl
GO_Central		 PMID:2420826 PMID:12466018 PMID:22829586 PMID:9794092 GO_REF:0000033 GO_REF:0000107, RGD:1641793 NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:157,352,373...157,372,144 		JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) involved_in ISO
IEA 		(PMID:18628520), (PMID:23132696)
GO_REF:0000107 		RGD
Ensembl		 PMID:18628520 PMID:23132696 GO_REF:0000107 NCBI chr 5:165,717,456...165,753,158
Ensembl chr 5:165,721,654...165,753,125 		JBrowse link
G Pgd phosphogluconate dehydrogenase involved_in
acts_upstream_of_or_within 		IMP
ISO
IEA
IBA 		(PMID:12466018), (PMID:5360673), (PMID:7496990)
(PMID:31586547)
GO_REF:0000107
GO_REF:0000033
(PMID:3858849) 		RGD
Ensembl
GO_Central		 PMID:3858849 PMID:5360673 PMID:7496990 PMID:12466018 PMID:31586547 More... GO_REF:0000033 GO_REF:0000107, RGD:1641793 NCBI chr 5:164,865,830...164,882,029
Ensembl chr 5:164,865,830...164,882,029 		JBrowse link
G Pgls 6-phosphogluconolactonase acts_upstream_of_or_within
involved_in 		IDA
ISO
IBA 		(PMID:31586547)
GO_REF:0000033 		RGD
GO_Central		 PMID:31586547 PMID:971315 GO_REF:0000033, RGD:2311501 NCBI chr16:18,334,299...18,339,785
Ensembl chr16:18,334,299...18,339,785 		JBrowse link
positive regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tigar TP53 induced glycolysis regulatory phosphatase involved_in IEA
ISO 		GO_REF:0000107
(PMID:24872551) 		Ensembl
RGD		 PMID:24872551 GO_REF:0000107 NCBI chr 4:161,613,306...161,632,248
Ensembl chr 4:161,613,306...161,632,229 		JBrowse link
regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 IDA RGD PMID:16234247 RGD:1625062 NCBI chr13:107,277,526...107,327,462
Ensembl chr13:107,257,239...107,327,432 		JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase involved_in ISO
IEA
IBA 		(PMID:25928429)
GO_REF:0000117
GO_REF:0000107
GO_REF:0000033 		RGD
UniProt
Ensembl
GO_Central		 PMID:25928429 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr 4:161,613,306...161,632,248
Ensembl chr 4:161,613,306...161,632,229 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    cellular process 18484
      metabolic process 11533
        generation of precursor metabolites and energy 528
          NADPH regeneration 23
            pentose-phosphate shunt + 18
            pentose-phosphate shunt, oxidative branch 4
            photosynthetic NADP+ reduction 0
Path 2
Term Annotations click to browse term
  biological_process 19315
    cellular process 18484
      metabolic process 11533
        primary metabolic process 10162
          nucleobase-containing compound metabolic process 5642
            nucleobase-containing small molecule metabolic process 693
              nucleoside phosphate metabolic process 660
                nucleotide metabolic process 503
                  nicotinamide nucleotide metabolic process 211
                    NADP+ metabolic process 43
                      NADPH regeneration 23
                        pentose-phosphate shunt + 18
                        pentose-phosphate shunt, oxidative branch 4
                        photosynthetic NADP+ reduction 0
paths to the root