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ONTOLOGY REPORT - ANNOTATIONS

Term:steroid catabolic process
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Accession:GO:0006706 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
Synonyms:exact_synonym: steroid breakdown;   steroid catabolism;   steroid degradation


show annotations for term's descendants           Sort by:
steroid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbr1 carbonyl reductase 1 IDA RGD PMID:7705364 RGD:69801 NCBI chr11:46,346,405...46,348,815
Ensembl chr11:46,378,411...46,381,104
Ensembl chr11:46,378,411...46,381,104 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 involved_in ISO
IBA
IEA 		(PMID:18356043)
GO_REF:0000033
GO_REF:0000107 		RGD
GO_Central
Ensembl		 PMID:18356043 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142 		JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 3:179,694,647...179,709,083
Ensembl chr 3:179,694,647...179,709,083 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 involved_in TAS
IEA 		GO_REF:0000117 UniProt
RGD		 PMID:12909643 GO_REF:0000117, RGD:1600873 NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:83,713,293...83,743,215 		JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 7:64,756,626...64,761,570
Ensembl chr 7:64,756,626...64,761,570 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 involved_in ISO (PMID:18356043) RGD PMID:18356043 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:107,277,526...107,327,462
Ensembl chr13:107,257,239...107,327,432 		JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 IDA RGD PMID:1527072 RGD:729939 NCBI chr 6:27,178,089...27,217,588
Ensembl chr 6:27,178,079...27,217,588 		JBrowse link
androgen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c14 aldo-keto reductase family 1, member C14 IDA RGD PMID:28552457 RGD:597621557 NCBI chr17:71,066,197...71,083,184
Ensembl chr17:71,066,200...71,083,157 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 involved_in ISO (PMID:26482249) RGD PMID:26482249 NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:63,449,148...63,476,917 		JBrowse link
G Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 involved_in ISO
IEA 		(PMID:12697717)
GO_REF:0000107 		RGD
Ensembl		 PMID:12697717 GO_REF:0000107 NCBI chr14:5,997,893...6,047,816
Ensembl chr14:5,997,906...6,047,811 		JBrowse link
G Spp1 secreted phosphoprotein 1 involved_in ISO
IEA 		(PMID:26482249)
GO_REF:0000107 		RGD
Ensembl		 PMID:26482249 GO_REF:0000107 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IDA RGD PMID:2339109 RGD:70289 NCBI chr 1:35,514,914...35,548,898
Ensembl chr 1:35,514,846...35,548,903 		JBrowse link
brexanolone catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 involved_in ISO
ISS 		(PMID:10896656), (PMID:11360992)
GO_REF:0000024 		RGD
UniProt		 PMID:10896656 PMID:11360992 GO_REF:0000024 NCBI chr 7:831,407...850,950
Ensembl chr 7:831,421...850,873 		JBrowse link
cholesterol catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1d1 aldo-keto reductase family 1, member D1 involved_in ISO
IEA 		(PMID:7508385)
GO_REF:0000107 		RGD
Ensembl		 PMID:7508385 GO_REF:0000107 NCBI chr 4:67,121,288...67,154,543
Ensembl chr 4:67,120,024...67,154,540 		JBrowse link
G Apoe apolipoprotein E acts_upstream_of_or_within ISO (PMID:9826706) RGD PMID:9826706 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
GO_REF:0000041
(PMID:9660774) 		UniProt
Ensembl
RGD		 PMID:9660774 GO_REF:0000024 GO_REF:0000041 GO_REF:0000107 NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:83,713,293...83,743,215 		JBrowse link
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 acts_upstream_of_or_within ISO (PMID:10748047) RGD PMID:10748047 NCBI chr 9:24,727,817...24,804,060
Ensembl chr 9:24,727,817...24,804,060 		JBrowse link
G Cyp46a1 cytochrome P450, family 46, subfamily a, polypeptide 1 involved_in ISO
IEA
IBA 		(PMID:14640697), (PMID:18621681), (PMID:25017465)
(PMID:10377398), (PMID:20193040)
GO_REF:0000117
GO_REF:0000002
GO_REF:0000033 		RGD
UniProt
InterPro
GO_Central		 PMID:10377398 PMID:14640697 PMID:18621681 PMID:20193040 PMID:25017465 GO_REF:0000002 GO_REF:0000033 GO_REF:0000117 NCBI chr 6:133,011,948...133,039,167
Ensembl chr 6:133,011,989...133,041,971 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 involved_in
acts_upstream_of_or_within 		IDA
ISO
IEA 		PMID:1694852
(PMID:11279518), (PMID:15845870)
GO_REF:0000117
GO_REF:0000107
GO_REF:0000002
GO_REF:0000041 		RGD
UniProt
Ensembl
InterPro		 PMID:11279518 PMID:15845870 PMID:1694852 GO_REF:0000002 GO_REF:0000041 GO_REF:0000107 GO_REF:0000117, RGD:70534 NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202 		JBrowse link
G Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 IDA RGD PMID:16081591 RGD:1599972 NCBI chr 1:191,842,688...191,845,919
Ensembl chr 1:191,842,636...191,845,921 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1928989 (PMID:10559220), (PMID:11278646) 		Ensembl
RGD		 PMID:10559220 PMID:11278646 GO_REF:0000107 NCBI chr12:36,957,302...37,023,982
Ensembl chr12:36,957,496...37,023,980 		JBrowse link
estrogen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sult1e1 sulfotransferase family 1E member 1 involved_in ISO
IEA 		(PMID:23207770)
GO_REF:0000107 		RGD
Ensembl		 PMID:23207770 GO_REF:0000107 NCBI chr14:20,700,444...20,718,719
Ensembl chr14:20,700,292...20,718,716 		JBrowse link
G Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C IDA RGD PMID:15502008 RGD:2317077 NCBI chr 9:96,187,382...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
glucocorticoid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 IDA RGD PMID:12460758 RGD:1625060 NCBI chr13:107,277,526...107,327,462
Ensembl chr13:107,257,239...107,327,432 		JBrowse link
G Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta involved_in ISO
IEA 		(PMID:15790729)
GO_REF:0000107 		RGD
Ensembl		 PMID:15790729 GO_REF:0000107 NCBI chr14:81,920,819...81,930,202
Ensembl chr14:81,920,590...81,947,930 		JBrowse link
progesterone catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:15471942)
MGI:3527218 (PMID:15471942) 		Ensembl
RGD		 PMID:15471942 GO_REF:0000107 NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438 		JBrowse link
vitamin D catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 involved_in TAS
IDA
ISO
IBA
IEA 		PMID:10231362
(PMID:16617161), (PMID:24893882), (PMID:29461981), (PMID:8506296), (PMID:8679605)
GO_REF:0000033
GO_REF:0000107 		RGD
GO_Central
Ensembl		 PMID:8506296 PMID:8679605 PMID:16617161 PMID:24893882 PMID:29461981 More... GO_REF:0000033 GO_REF:0000107, RGD:625496, RGD:14995316, RGD:14995311 NCBI chr 3:179,694,647...179,709,083
Ensembl chr 3:179,694,647...179,709,083 		JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 involved_in IEA
IDA
IBA
ISO 		GO_REF:0000107
PMID:9333115
GO_REF:0000033
(PMID:9295274) 		Ensembl
GO_Central
RGD		 PMID:9295274 PMID:9333115 GO_REF:0000033 GO_REF:0000107, RGD:69373 NCBI chr 7:64,756,626...64,761,570
Ensembl chr 7:64,756,626...64,761,570 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 involved_in ISO (PMID:29461981) RGD PMID:29461981 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Fgf23 fibroblast growth factor 23 involved_in ISO
IEA 		(PMID:15040831)
GO_REF:0000107 		RGD
Ensembl		 PMID:15040831 GO_REF:0000107 NCBI chr 4:161,600,439...161,609,991
Ensembl chr 4:161,600,383...161,609,991 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    cellular process 18484
      metabolic process 11533
        catabolic process 2936
          lipid catabolic process 366
            steroid catabolic process 28
              (17Z)-protosta-17(20),24-dien-3beta-ol catabolic process 0
              C21-steroid hormone catabolic process + 1
              androgen catabolic process 5
              brexanolone catabolic process 1
              ecdysteroid catabolic process + 0
              ergosteryl 3-beta-D-glucoside catabolic process 0
              estrogen catabolic process 2
              glucocorticoid catabolic process + 2
              helvolic acid catabolic process 0
              mineralocorticoid catabolic process + 0
              phytosteroid catabolic process + 0
              sterol catabolic process + 8
              vitamin D catabolic process + 4
Path 2
Term Annotations click to browse term
  biological_process 19315
    cellular process 18484
      metabolic process 11533
        primary metabolic process 10162
          lipid metabolic process 1489
            steroid metabolic process 377
              steroid catabolic process 28
                (17Z)-protosta-17(20),24-dien-3beta-ol catabolic process 0
                C21-steroid hormone catabolic process + 1
                androgen catabolic process 5
                brexanolone catabolic process 1
                ecdysteroid catabolic process + 0
                ergosteryl 3-beta-D-glucoside catabolic process 0
                estrogen catabolic process 2
                glucocorticoid catabolic process + 2
                helvolic acid catabolic process 0
                mineralocorticoid catabolic process + 0
                phytosteroid catabolic process + 0
                sterol catabolic process + 8
                vitamin D catabolic process + 4
paths to the root