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ONTOLOGY REPORT - ANNOTATIONS

Term:mineralocorticoid biosynthetic process
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Accession:GO:0006705 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
Synonyms:exact_synonym: mineralocorticoid anabolism;   mineralocorticoid biosynthesis;   mineralocorticoid formation;   mineralocorticoid synthesis
 xref: Reactome:R-HSA-193993 "Mineralocorticoid biosynthesis"


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aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1H calcium voltage-gated channel subunit alpha1 H involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:39,510,129...39,533,129
Ensembl chr 6:39,510,121...39,533,753 		JBrowse link
G CYP11B1 cytochrome P450 family 11 subfamily B member 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:1686470), (PMID:8645611) MGI
GO_Central		 PMID:1686470 PMID:8645611 GO_REF:0000033 NCBI chr13:36,866,476...36,880,625 JBrowse link
G LOC119876933 cytochrome P450 11B1, mitochondrial-like involved_in IBA GO_Central GO_REF:0000033
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:15,199,667...15,211,509
Ensembl chr24:15,200,291...15,212,217 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:23,089,429...23,202,176
Ensembl chr12:23,089,459...23,202,348 		JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:35,032,501...35,074,664
Ensembl chr21:35,033,552...35,074,664 		JBrowse link
G REST RE1 silencing transcription factor involved_in ISO PMID:19342457
(PMID:19342457)		 UniProt PMID:19342457 RGD:4891166 NCBI chr13:49,041,082...49,062,596
Ensembl chr13:49,041,047...49,059,388 		JBrowse link
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:7,780,763...7,833,095
Ensembl chr35:7,804,231...7,831,845 		JBrowse link
G DAB2 DAB adaptor protein 2 ISO RGD PMID:17303656 RGD:7243836 NCBI chr 4:69,625,874...69,648,349
Ensembl chr 4:69,625,527...69,648,321 		JBrowse link
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:77,112,045...77,129,702
Ensembl chr 2:77,101,300...77,127,111 		JBrowse link
regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLCN2 chloride voltage-gated channel 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:17,224,136...17,238,755
Ensembl chr34:17,223,215...17,239,621 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22103
    cellular process 21633
      metabolic process 15381
        hormone metabolic process 228
          hormone biosynthetic process 67
            mineralocorticoid biosynthetic process 11
              aldosterone biosynthetic process + 11
Path 2
Term Annotations click to browse term
  biological_process 22103
    cellular process 21633
      metabolic process 15381
        primary metabolic process 13982
          lipid metabolic process 1345
            lipid biosynthetic process 683
              steroid biosynthetic process 167
                steroid hormone biosynthetic process 42
                  mineralocorticoid biosynthetic process 11
                    aldosterone biosynthetic process + 11
paths to the root