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ONTOLOGY REPORT - ANNOTATIONS

Term:mineralocorticoid biosynthetic process
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Accession:GO:0006705 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
Synonyms:exact_synonym: mineralocorticoid anabolism;   mineralocorticoid biosynthesis;   mineralocorticoid formation;   mineralocorticoid synthesis
 xref: Reactome:R-HSA-193993 "Mineralocorticoid biosynthesis"

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aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1h calcium voltage-gated channel subunit alpha1 H involved_in ISO PMID:19342457
(PMID:19342457)		 UniProt PMID:19342457 RGD:4891166 NCBI chrNW_004955442:16,047,965...16,108,862
Ensembl chrNW_004955442:16,045,895...16,108,862 		JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chrNW_004955415:17,048,374...17,058,172
Ensembl chrNW_004955415:17,048,030...17,060,181 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chrNW_004955411:450,674...557,213
Ensembl chrNW_004955411:450,674...558,650 		JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) UniProt PMID:16981135 NCBI chrNW_004955414:27,466,636...27,507,186
Ensembl chrNW_004955414:27,456,770...27,508,109 		JBrowse link
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp6 bone morphogenetic protein 6 involved_in ISO (PMID:16527843) UniProt PMID:16527843 NCBI chrNW_004955465:6,053,600...6,201,254
Ensembl chrNW_004955465:6,054,931...6,200,377 		JBrowse link
G Dab2 DAB adaptor protein 2 ISO RGD PMID:17303656 RGD:7243836 NCBI chrNW_004955426:23,852,752...23,883,030 JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO (PMID:16981135) UniProt PMID:16981135 NCBI chrNW_004955452:2,319,446...2,344,740
Ensembl chrNW_004955452:2,319,446...2,344,989 		JBrowse link
regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcn2 chloride voltage-gated channel 2 involved_in ISO (PMID:29403011) UniProt PMID:29403011 NCBI chrNW_004955420:23,138,558...23,152,462
Ensembl chrNW_004955420:23,138,605...23,152,311 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12563
    cellular process 12002
      metabolic process 7932
        hormone metabolic process 181
          hormone biosynthetic process 50
            mineralocorticoid biosynthetic process 8
              aldosterone biosynthetic process + 8
Path 2
Term Annotations click to browse term
  biological_process 12563
    cellular process 12002
      metabolic process 7932
        primary metabolic process 6950
          lipid metabolic process 999
            lipid biosynthetic process 526
              steroid biosynthetic process 122
                steroid hormone biosynthetic process 33
                  mineralocorticoid biosynthetic process 8
                    aldosterone biosynthetic process + 8
paths to the root