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ONTOLOGY REPORT - ANNOTATIONS

Term:mineralocorticoid biosynthetic process
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Accession:GO:0006705 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
Synonyms:exact_synonym: mineralocorticoid anabolism;   mineralocorticoid biosynthesis;   mineralocorticoid formation;   mineralocorticoid synthesis
 xref: Reactome:R-HSA-193993 "Mineralocorticoid biosynthesis"


show annotations for term's descendants           Sort by:
aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1H calcium voltage-gated channel subunit alpha1 H involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:1,195,364...1,222,917 JBrowse link
G CYP11B1 cytochrome P450 family 11 subfamily B member 1 involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:11832364 GO_REF:0000107 GO_REF:0000118 RGD:727991 NCBI chr 8:139,584,976...139,592,466
Ensembl chr 8:142,629,127...142,634,654 		JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:1686470), (PMID:8645611) Ensembl
TreeGrafter
MGI		 PMID:1686470 PMID:8645611 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:139,622,632...139,630,014
Ensembl chr 8:142,666,534...142,672,575 		JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:55,302,721...55,425,248
Ensembl chr 6:56,936,850...57,059,519 		JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:12,131,306...12,177,906
Ensembl chr11:11,824,955...11,871,139 		JBrowse link
G REST RE1 silencing transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:66,984,466...67,012,301
Ensembl chr 4:73,526,085...73,582,242 		JBrowse link
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:7,564,164...7,720,341
Ensembl chr 6:7,848,249...8,000,649 		JBrowse link
G DAB2 DAB adaptor protein 2 ISO RGD PMID:17303656 RGD:7243836 NCBI chr 5:70,951,198...71,004,836
Ensembl chr 5:76,022,143...76,041,443 		JBrowse link
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:21,310,228...21,335,985
Ensembl chr 1:22,255,056...22,268,801 		JBrowse link
regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLCN2 chloride voltage-gated channel 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:181,383,608...181,399,200
Ensembl chr 3:189,862,489...189,881,049 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19447
    cellular process 19000
      metabolic process 12941
        hormone metabolic process 240
          hormone biosynthetic process 70
            mineralocorticoid biosynthetic process 11
              aldosterone biosynthetic process + 11
Path 2
Term Annotations click to browse term
  biological_process 19447
    cellular process 19000
      metabolic process 12941
        primary metabolic process 11364
          lipid metabolic process 1310
            lipid biosynthetic process 677
              steroid biosynthetic process 154
                steroid hormone biosynthetic process 43
                  mineralocorticoid biosynthetic process 11
                    aldosterone biosynthetic process + 11
paths to the root