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ONTOLOGY REPORT - ANNOTATIONS


Term:protein targeting to vacuole
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Accession:GO:0006623 term browser browse the term
Definition:The process of directing proteins towards the vacuole, usually using signals contained within the protein.
Synonyms:exact_synonym: protein vacuolar targeting;   protein-vacuole targeting;   vacuolar protein sorting



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protein targeting to vacuole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP3D1 adaptor related protein complex 3 subunit delta 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:76,428,443...76,471,266
Ensembl chr 2:76,428,476...76,471,257
JBrowse link
G MON1A MON1 homolog A, secretory trafficking associated involved_in IEA UniProt
InterPro
GO_REF:0000002 GO_REF:0000104 NCBI chr13:32,426,733...32,437,735
Ensembl chr13:32,426,736...32,437,862
JBrowse link
G MON1B MON1 homolog B, secretory trafficking associated involved_in IEA InterPro
UniProt
GO_REF:0000002 GO_REF:0000104 NCBI chr 6:10,713,721...10,725,474
Ensembl chr 6:10,713,719...10,725,457
JBrowse link
G PIK3R4 phosphoinositide-3-kinase regulatory subunit 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr13:1,730,988...1,815,555
Ensembl chr13:1,731,023...1,815,556
JBrowse link
G VPS13A vacuolar protein sorting 13 homolog A involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:230,069,339...230,331,343
Ensembl chr 1:230,069,368...230,331,200
JBrowse link
G VPS13C vacuolar protein sorting 13 homolog C involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:109,931,269...110,105,519
Ensembl chr 1:109,931,264...110,104,241
JBrowse link
G VPS13D vacuolar protein sorting 13 homolog D involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:72,256,865...72,514,256
Ensembl chr 6:72,256,828...72,510,058
JBrowse link
G VPS37A VPS37A subunit of ESCRT-I involved_in IBA GO_Central GO_REF:0000033 NCBI chr17:4,949,632...5,014,842
Ensembl chr17:4,949,644...4,988,074
JBrowse link
G VPS37B VPS37B subunit of ESCRT-I involved_in IBA GO_Central GO_REF:0000033 NCBI chr14:29,963,087...29,994,650
Ensembl chr14:29,962,042...29,994,646
JBrowse link
G VPS37C VPS37C subunit of ESCRT-I involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:10,614,198...10,643,545
Ensembl chr 2:10,632,927...10,643,539
JBrowse link
G VPS37D VPS37D subunit of ESCRT-I involved_in IBA GO_Central GO_REF:0000033 NCBI chr 3:10,947,403...10,951,271
Ensembl chr 3:10,947,403...10,951,273
JBrowse link
G VPS41 VPS41 subunit of HOPS complex involved_in IEA
IBA
InterPro
GO_Central
GO_REF:0000002 GO_REF:0000033 NCBI chr18:55,293,655...55,466,628
Ensembl chr18:55,301,624...55,466,628
JBrowse link
G VPS54 VPS54 subunit of GARP complex involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:77,856,093...77,978,194
Ensembl chr 3:77,856,138...77,975,429
JBrowse link
G VPS8 VPS8 subunit of CORVET complex involved_in IEA
IBA
InterPro
GO_Central
GO_REF:0000002 GO_REF:0000033 NCBI chr13:122,693,681...122,953,625
Ensembl chr13:122,693,760...122,950,420
JBrowse link
N-glycan processing to lysosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GNPTAB N-acetylglucosamine-1-phosphate transferase subunits alpha and beta involved_in IEA
IBA
Ensembl
GO_Central
GO_REF:0000033 GO_REF:0000107 NCBI chr 5:82,264,640...82,460,819
Ensembl chr 5:82,361,872...82,460,814
JBrowse link
protein targeting to lysosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP3B1 adaptor related protein complex 3 subunit beta 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:86,875,922...87,142,722
Ensembl chr 2:86,873,290...87,142,768
JBrowse link
G AP4M1 adaptor related protein complex 4 subunit mu 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:8,013,701...8,017,701
Ensembl chr 3:8,013,747...8,017,700
JBrowse link
G GCC2 GRIP and coiled-coil domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:47,718,251...47,759,060
Ensembl chr 3:47,718,254...47,758,999
JBrowse link
G GGA3 golgi associated, gamma adaptin ear containing, ARF binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:6,051,854...6,072,424
Ensembl chr12:6,055,696...6,074,478
JBrowse link
G HGS hepatocyte growth factor-regulated tyrosine kinase substrate involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:1,207,036...1,219,750
Ensembl chr12:1,207,036...1,219,715
JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:87,363,911...87,390,371
Ensembl chr 6:87,363,911...87,390,347
JBrowse link
G LHCGR luteinizing hormone/choriogonadotropin receptor ISO chorionic gonadotropin after receptor internalization RGD PMID:10847593 RGD:2292601 NCBI chr 3:91,964,415...92,023,821
Ensembl chr 3:91,964,415...92,021,398
JBrowse link
G M6PR mannose-6-phosphate receptor, cation dependent involved_in IEA
IBA
InterPro
GO_Central
GO_REF:0000002 GO_REF:0000033 NCBI chr 5:62,537,751...62,557,674
Ensembl chr 5:62,537,700...62,557,688
JBrowse link
G NCOA4 nuclear receptor coactivator 4 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr14:90,505,614...90,531,302
Ensembl chr14:90,505,110...90,531,118
JBrowse link
G NDP norrin cystine knot growth factor NDP acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr  X:39,208,115...39,235,879
Ensembl chr  X:39,208,119...39,235,758
JBrowse link
G NEDD4 NEDD4 E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:115,941,945...116,069,884
Ensembl chr 1:115,941,940...116,070,305
JBrowse link
G RAB7A RAB7A, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:71,777,422...71,886,758
Ensembl chr13:71,777,424...71,852,694
JBrowse link
G SCARB2 scavenger receptor class B member 2 involved_in IEA
IBA
Ensembl
GO_Central
GO_REF:0000033 GO_REF:0000107 NCBI chr 8:71,838,395...71,910,461
Ensembl chr 8:71,838,397...71,940,607
JBrowse link
G SNX16 sorting nexin 16 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:54,801,363...54,837,986
Ensembl chr 4:54,801,394...54,837,981
JBrowse link
G SORL1 sortilin related receptor 1 involved_in IEA
IBA
Ensembl
GO_Central
GO_REF:0000033 GO_REF:0000107 NCBI chr 9:48,435,350...48,653,670
Ensembl chr 9:48,435,345...48,653,655
JBrowse link
G SORT1 sortilin 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:110,721,110...110,791,406
Ensembl chr 4:110,720,947...110,789,070
JBrowse link
G VPS4A vacuolar protein sorting 4 homolog A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:17,657,792...17,669,560
Ensembl chr 6:17,654,638...17,669,841
JBrowse link
G VPS53 VPS53 subunit of GARP complex involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:47,141,749...47,291,169
Ensembl chr12:47,143,098...47,291,161
JBrowse link
G VPS54 VPS54 subunit of GARP complex involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:77,856,093...77,978,194
Ensembl chr 3:77,856,138...77,975,429
JBrowse link
G WASHC1 WASH complex subunit 1 involved_in ISO (PMID:20175130) UniProt PMID:20175130 NCBI chr 5:67,395,737...67,412,408
Ensembl chr 5:67,394,875...67,412,431
JBrowse link
G ZFYVE16 zinc finger FYVE-type containing 16 involved_in IEA
IBA
Ensembl
GO_Central
GO_REF:0000033 GO_REF:0000107 NCBI chr 2:89,044,860...89,109,237
Ensembl chr 2:89,045,362...89,106,975
JBrowse link
protein targeting to lysosome involved in chaperone-mediated autophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLU clusterin involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:11,336,585...11,352,569
Ensembl chr14:11,336,595...11,349,764
JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:49,982,278...49,986,760
Ensembl chr 9:49,982,284...49,990,508
JBrowse link
G LAMP2 lysosomal associated membrane protein 2 acts_upstream_of_or_within
involved_in
ISO
IBA
IEA
PMID:18644871 MGI
GO_Central
Ensembl
PMID:18644871 GO_REF:0000033 GO_REF:0000107 RGD:10412301 NCBI chr  X:98,586,718...98,623,939
Ensembl chr  X:98,581,992...98,623,940
JBrowse link
protein targeting to vacuole involved in autophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:6,037,732...6,142,569
Ensembl chr 3:6,037,741...6,142,575
JBrowse link
G SQSTM1 sequestosome 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:78,752,768...78,763,998
Ensembl chr 2:78,752,771...78,763,938
JBrowse link
regulation of protein targeting to vacuolar membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G VAMP7 vesicle associated membrane protein 7 acts_upstream_of_or_within ISO (PMID:18227281) MGI PMID:18227281 NCBI chr  X:125,863,266...125,917,232
Ensembl chr  X:125,863,292...125,917,225
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18944
    localization 5419
      cellular localization 3546
        intracellular transport 1343
          vacuolar transport 160
            protein targeting to vacuole 41
              cytoplasm to vacuole targeting by the Cvt pathway + 0
              cytoplasm to vacuole targeting by the NVT pathway 0
              protein targeting to lysosome + 25
              protein targeting to vacuolar membrane + 1
              protein targeting to vacuole involved in autophagy + 5
Path 2
Term Annotations click to browse term
  biological_process 18944
    localization 5419
      macromolecule localization 3045
        cellular macromolecule localization 2603
          protein localization 2591
            protein localization to organelle 1052
              establishment of protein localization to organelle 480
                establishment of protein localization to vacuole 48
                  protein targeting to vacuole 41
                    cytoplasm to vacuole targeting by the Cvt pathway + 0
                    cytoplasm to vacuole targeting by the NVT pathway 0
                    protein targeting to lysosome + 25
                    protein targeting to vacuolar membrane + 1
                    protein targeting to vacuole involved in autophagy + 5
paths to the root