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ONTOLOGY REPORT - ANNOTATIONS

Term:protein targeting to vacuole
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Accession:GO:0006623 term browser browse the term
Definition:The process of directing proteins towards the vacuole, usually using signals contained within the protein.
Synonyms:exact_synonym: protein vacuolar targeting;   protein-vacuole targeting;   vacuolar protein sorting


show annotations for term's descendants           Sort by:
protein targeting to vacuole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap3d1 adaptor related protein complex 3 subunit delta 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:9,620,909...9,656,350
Ensembl chr 7:8,970,291...9,005,643 		JBrowse link
G Mon1a MON1 homolog A, secretory trafficking associated involved_in IEA GO_REF:0000104
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr 8:108,574,272...108,593,163
Ensembl chr 8:108,574,388...108,593,156 		JBrowse link
G Mon1b MON1 homolog B, secretory trafficking associated involved_in IEA GO_REF:0000104
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr19:58,526,503...58,534,478
Ensembl chr19:41,617,364...41,625,347 		JBrowse link
G Pik3r4 phosphoinositide-3-kinase, regulatory subunit 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:115,146,660...115,195,326
Ensembl chr 8:106,267,954...106,316,584 		JBrowse link
G Vps13a vacuolar protein sorting 13 homolog A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:223,328,784...223,555,500
Ensembl chr 1:213,901,999...214,128,555 		JBrowse link
G Vps13c vacuolar protein sorting 13 homolog C involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:77,359,499...77,533,009
Ensembl chr 8:68,478,395...68,651,895 		JBrowse link
G Vps13d vacuolar protein sorting 13 homolog D involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:162,113,732...162,339,121
Ensembl chr 5:156,830,512...157,055,891 		JBrowse link
G Vps37b VPS37B subunit of ESCRT-I involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:38,220,973...38,249,935
Ensembl chr12:32,560,047...32,589,014 		JBrowse link
G Vps37c VPS37C subunit of ESCRT-I involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:216,760,675...216,787,198
Ensembl chr 1:207,336,731...207,362,289 		JBrowse link
G Vps37d VPS37D subunit of ESCRT-I involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:27,245,755...27,251,214
Ensembl chr12:21,609,182...21,614,659 		JBrowse link
G Vps41 VPS41 subunit of HOPS complex involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000002		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr17:50,758,732...50,923,129
Ensembl chr17:46,063,124...46,227,791 		JBrowse link
G Vps54 VPS54 subunit of GARP complex involved_in ISO
IEA		 MGI:1857091 (PMID:23708095)
GO_REF:0000107		 RGD
Ensembl		 PMID:23708095 GO_REF:0000107 NCBI chr14:99,580,120...99,657,178
Ensembl chr14:95,378,012...95,455,857 		JBrowse link
G Vps8 VPS8 subunit of CORVET complex involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000002		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr11:79,402,236...79,634,234
Ensembl chr11:79,402,239...79,634,133 		JBrowse link
N-glycan processing to lysosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnptab N-acetylglucosamine-1-phosphate transferase subunits alpha and beta involved_in ISO
IEA
IBA		 (PMID:19938078), (PMID:25505245)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:19938078 PMID:25505245 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:22,800,502...22,866,336
Ensembl chr 7:22,800,485...22,866,933 		JBrowse link
protein targeting to lysosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap3b1 adaptor related protein complex 3 subunit beta 1 acts_upstream_of_or_within ISO MGI:1856989 (PMID:14557411) RGD PMID:14557411 NCBI chr 2:27,331,241...27,535,683
Ensembl chr 2:25,600,040...25,800,935 		JBrowse link
G Ap4m1 adaptor related protein complex 4 subunit mu 1 involved_in ISO
IEA		 (PMID:11139587)
GO_REF:0000107		 RGD
Ensembl		 PMID:11139587 GO_REF:0000107 NCBI chr12:22,163,474...22,171,734
Ensembl chr12:17,049,777...17,058,026 		JBrowse link
G Gcc2 GRIP and coiled-coil domain containing 2 involved_in ISO
ISS		 (PMID:16885419)
GO_REF:0000024		 RGD
UniProt		 PMID:16885419 GO_REF:0000024 NCBI chr20:26,788,472...26,836,728
Ensembl chr20:26,247,404...26,293,613 		JBrowse link
G Gga3 golgi associated, gamma adaptin ear containing, ARF binding protein 3 involved_in ISO
IEA		 UniProtKB:P46934 (PMID:17116753)
GO_REF:0000107		 RGD
Ensembl		 PMID:17116753 GO_REF:0000107 NCBI chr10:101,324,378...101,342,373
Ensembl chr10:100,825,426...100,844,462 		JBrowse link
G Hgs hepatocyte growth factor-regulated tyrosine kinase substrate involved_in ISO
IEA		 (PMID:18767904)
GO_REF:0000107		 RGD
Ensembl		 PMID:18767904 GO_REF:0000107 NCBI chr10:106,237,988...106,256,174
Ensembl chr10:105,739,296...105,757,835 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:18619870) RGD PMID:18619870 NCBI chr 5:148,371,880...148,393,927
Ensembl chr 5:143,087,759...143,109,807 		JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor IMP chorionic gonadotropin after receptor internalization RGD PMID:10847593 RGD:2292601 NCBI chr 6:11,415,361...11,480,834
Ensembl chr 6:5,661,871...5,724,521 		JBrowse link
G Lyset lysosomal enzyme trafficking factor acts_upstream_of_or_within ISO (PMID:36074821) RGD PMID:36074821 NCBI chr 6:127,649,401...127,651,143
Ensembl chr 6:121,884,643...121,886,275 		JBrowse link
G M6pr mannose-6-phosphate receptor, cation dependent involved_in IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 4:155,501,080...155,510,219
Ensembl chr 4:155,500,921...155,510,216 		JBrowse link
G M6pr-ps1 mannose-6-phosphate receptor, cation dependent, pseudogene 1 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000002		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr  X:82,129,168...82,131,403
Ensembl chr  X:82,129,322...82,130,158 		JBrowse link
G Ncoa4 nuclear receptor coactivator 4 acts_upstream_of_or_within ISO (PMID:25327288) RGD PMID:25327288 NCBI chr16:7,395,502...7,415,846
Ensembl chr16:7,366,542...7,409,641
Ensembl chr16:7,366,542...7,409,641 		JBrowse link
G Ndp norrin cystine knot growth factor NDP acts_upstream_of_or_within ISO
IEA		 (PMID:28675177)
GO_REF:0000107		 RGD
Ensembl		 PMID:28675177 GO_REF:0000107 NCBI chr  X:8,379,569...8,404,019
Ensembl chr  X:5,796,487...5,820,934 		JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase involved_in ISO
IEA		 UniProtKB:Q9NZ52 (PMID:17116753)
GO_REF:0000107		 RGD
Ensembl		 PMID:17116753 GO_REF:0000107 NCBI chr 8:82,264,751...82,349,642
Ensembl chr 8:73,383,695...73,468,951 		JBrowse link
G Rab7a RAB7A, member RAS oncogene family involved_in ISO
IEA		 (PMID:22115783)
GO_REF:0000107		 RGD
Ensembl		 PMID:22115783 GO_REF:0000107 NCBI chr 4:122,019,281...122,068,067
Ensembl chr 4:120,461,963...120,506,889 		JBrowse link
G Scarb2 scavenger receptor class B, member 2 involved_in ISO
IBA
IEA		 (PMID:18022370)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:18022370 GO_REF:0000033 GO_REF:0000107 NCBI chr14:15,842,583...15,894,123
Ensembl chr14:15,558,236...15,609,813 		JBrowse link
G Snx16 sorting nexin 16 involved_in ISO
IEA
ISS		 (PMID:12813048)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:12813048 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:93,242,779...93,265,048
Ensembl chr 2:91,336,092...91,357,619 		JBrowse link
G Sorl1 sortilin related receptor 1 involved_in ISO
IEA
IBA		 (PMID:24523320)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:24523320 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:51,238,713...51,401,458
Ensembl chr 8:42,341,704...42,504,513 		JBrowse link
G Sort1 sortilin 1 acts_upstream_of_or_within ISO
IEA		 MGI:4397584 (PMID:19732768)
GO_REF:0000107		 RGD
Ensembl		 PMID:19732768 GO_REF:0000107 NCBI chr 2:198,609,466...198,690,481
Ensembl chr 2:195,924,099...196,002,354 		JBrowse link
G Vps4a vacuolar protein sorting 4 homolog A involved_in ISO
IEA		 (PMID:16973552)
GO_REF:0000107		 RGD
Ensembl		 PMID:16973552 GO_REF:0000107 NCBI chr19:51,838,411...51,858,639
Ensembl chr19:34,934,961...34,948,887 		JBrowse link
G Vps53 VPS53 subunit of GARP complex involved_in ISO
IEA		 (PMID:28658628)
GO_REF:0000107		 RGD
Ensembl		 PMID:28658628 GO_REF:0000107 NCBI chr10:60,919,820...61,038,674
Ensembl chr10:60,919,820...61,038,676 		JBrowse link
G Vps54 VPS54 subunit of GARP complex involved_in IEA
ISO		 GO_REF:0000107
MGI:1857091 (PMID:28658628), (PMID:32345721)		 Ensembl
RGD		 PMID:28658628 PMID:32345721 GO_REF:0000107 NCBI chr14:99,580,120...99,657,178
Ensembl chr14:95,378,012...95,455,857 		JBrowse link
G Washc1 WASH complex subunit 1 involved_in ISO (PMID:20175130) RGD PMID:20175130 NCBI chr 9:113,169,730...113,179,829
Ensembl chr 9:105,722,899...105,733,009 		JBrowse link
G Zfyve16 zinc finger FYVE-type containing 16 involved_in ISO
IBA		 (PMID:11546807)
GO_REF:0000033		 RGD
GO_Central		 PMID:11546807 GO_REF:0000033 NCBI chr 2:23,713,018...23,757,576
Ensembl chr 2:23,713,766...23,756,990 		JBrowse link
protein targeting to lysosome involved in chaperone-mediated autophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clu clusterin involved_in ISO
IEA		 (PMID:9228033)
GO_REF:0000107		 RGD
Ensembl		 PMID:9228033 GO_REF:0000107 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 involved_in ISS
ISO		 GO_REF:0000024
(PMID:11559757), (PMID:26212789), (PMID:36586411)		 UniProt
RGD		 PMID:11559757 PMID:26212789 PMID:36586411 GO_REF:0000024 NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 involved_in
acts_upstream_of_or_within		 ISO
ISS
IMP
IGI
IEA
IBA		 (PMID:27628032)
GO_REF:0000024
PMID:18644871
GO_REF:0000107
GO_REF:0000033		 RGD
UniProt
Ensembl
GO_Central		 PMID:27628032 PMID:18644871 PMID:18644871 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:10412301, RGD:10412301 NCBI chr  X:122,038,734...122,087,745
Ensembl chr  X:117,057,606...117,260,522 		JBrowse link
protein targeting to vacuole involved in autophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irgm immunity-related GTPase M involved_in ISO (PMID:29420192) RGD PMID:29420192 NCBI chr10:33,734,640...33,742,720
Ensembl chr10:33,233,455...33,241,578 		JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 involved_in ISO
IEA		 (PMID:22020285)
GO_REF:0000107		 RGD
Ensembl		 PMID:22020285 GO_REF:0000107 NCBI chr12:14,748,717...14,840,273
Ensembl chr12:9,635,025...9,726,519 		JBrowse link
G Sqstm1 sequestosome 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:27498865), (PMID:34893540), (PMID:36221902), (PMID:37802024)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:27498865 PMID:34893540 PMID:36221902 PMID:37802024 GO_REF:0000024 GO_REF:0000107 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
regulation of protein targeting to vacuolar membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vamp7 vesicle-associated membrane protein 7 acts_upstream_of_or_within ISO (PMID:18227281) RGD PMID:18227281 NCBI chr12:21,842,206...21,958,556
Ensembl chr12:16,728,524...16,764,097 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    localization 5739
      cellular localization 3705
        intracellular transport 1406
          vacuolar transport 162
            protein targeting to vacuole 43
              cytoplasm to vacuole targeting by the Cvt pathway + 0
              cytoplasm to vacuole targeting by the NVT pathway 0
              protein targeting to lysosome + 27
              protein targeting to vacuolar membrane + 1
              protein targeting to vacuole involved in autophagy + 6
Path 2
Term Annotations click to browse term
  biological_process 20567
    localization 5739
      macromolecule localization 3200
        cellular macromolecule localization 2734
          protein localization 2722
            protein localization to organelle 1077
              establishment of protein localization to organelle 490
                establishment of protein localization to vacuole 50
                  protein targeting to vacuole 43
                    cytoplasm to vacuole targeting by the Cvt pathway + 0
                    cytoplasm to vacuole targeting by the NVT pathway 0
                    protein targeting to lysosome + 27
                    protein targeting to vacuolar membrane + 1
                    protein targeting to vacuole involved in autophagy + 6
paths to the root