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ONTOLOGY REPORT - ANNOTATIONS

Term:indolalkylamine metabolic process
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Accession:GO:0006586 term browser browse the term
Definition:The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group.
Synonyms:exact_synonym: indolalkylamine metabolism
 broad_synonym: indolamine metabolic process;   indolamine metabolism


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'de novo' NAD+ biosynthetic process from L-tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718 		JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in
acts_upstream_of_or_within 		IEA
IBA
ISO 		GO_REF:0000104
GO_REF:0000033
MGI:6723745 (PMID:30127395), (PMID:30478397), (PMID:37078472) 		UniProt
GO_Central
RGD		 PMID:30127395 PMID:30478397 PMID:37078472 GO_REF:0000033 GO_REF:0000104 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730 		JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:67,459,158...67,498,052
Ensembl chr16:67,459,190...67,496,324 		JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881 		JBrowse link
G Kynu kynureninase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
G Nadsyn1 NAD synthetase 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:31883644)
(PMID:25423279) 		UniProt
RGD		 PMID:25423279 PMID:31883644 GO_REF:0000024 NCBI chr 1:198,981,559...199,009,853
Ensembl chr 1:198,981,604...199,009,869 		JBrowse link
G Nmnat2 nicotinamide nucleotide adenylyltransferase 2 involved_in ISO (PMID:25423279) RGD PMID:25423279 NCBI chr13:65,105,950...65,277,350
Ensembl chr13:65,105,950...65,278,484 		JBrowse link
G Qprt quinolinate phosphoribosyltransferase involved_in ISO MGI:6723745 (PMID:30127395), (PMID:30478397), (PMID:37078472) RGD PMID:30127395 PMID:30478397 PMID:37078472 NCBI chr 1:181,718,189...181,733,486
Ensembl chr 1:181,718,190...181,733,486 		JBrowse link
L-tryptophan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acmsd aminocarboxymuconate semialdehyde decarboxylase IDA RGD PMID:11802786 RGD:70243 NCBI chr13:39,200,412...39,245,954
Ensembl chr13:39,200,314...39,245,209 		JBrowse link
G Afmid arylformamidase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718 		JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in IEA
ISO 		GO_REF:0000104
MGI:1918039 (PMID:28792876) 		UniProt
RGD		 PMID:28792876 GO_REF:0000104 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 involved_in IEA GO_REF:0000117
GO_REF:0000043 		UniProt GO_REF:0000043 GO_REF:0000117 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730 		JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 involved_in IEA GO_REF:0000117
GO_REF:0000043 		UniProt GO_REF:0000043 GO_REF:0000117 NCBI chr16:67,459,158...67,498,052
Ensembl chr16:67,459,190...67,496,324 		JBrowse link
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:17356132), (PMID:25767141) RGD PMID:17356132 PMID:25767141 NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562 		JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in IEA GO_REF:0000104
GO_REF:0000002 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881 		JBrowse link
G Kynu kynureninase involved_in ISO
IEA 		(PMID:17334708)
GO_REF:0000002
GO_REF:0000104 		RGD
InterPro
UniProt		 PMID:17334708 GO_REF:0000002 GO_REF:0000104 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase involved_in IEA GO_REF:0000043
GO_REF:0000117 		UniProt GO_REF:0000043 GO_REF:0000117 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511 		JBrowse link
L-tryptophan catabolic process to acetyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kynu kynureninase IDA RGD PMID:7236232 RGD:2303721 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase involved_in IDA
IBA 		GO_REF:0000033 GO_Central
RGD		 PMID:7236232 GO_REF:0000033, RGD:2303721 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511 		JBrowse link
L-tryptophan catabolic process to indole-3-acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:32818467), (PMID:32866000) RGD PMID:32818467 PMID:32866000 NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562 		JBrowse link
L-tryptophan catabolic process to kynurenine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase involved_in
acts_upstream_of_or_within 		IEA
ISO
IBA 		GO_REF:0000041
GO_REF:0000002
GO_REF:0000104
GO_REF:0000107
(PMID:15866519)
GO_REF:0000033 		UniProt
InterPro
Ensembl
RGD
GO_Central		 PMID:15866519 GO_REF:0000002 GO_REF:0000033 GO_REF:0000041 GO_REF:0000104 GO_REF:0000107 NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 involved_in
acts_upstream_of_or_within 		IDA
IEA
ISO
IBA 		GO_REF:0000002
GO_REF:0000107
GO_REF:0000104
(PMID:11751753), (PMID:2419335)
GO_REF:0000033 		InterPro
Ensembl
UniProt
RGD
GO_Central		 PMID:2419335 PMID:11751753 PMID:10719243 PMID:11513477 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107, RGD:2290190, RGD:2290543 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730 		JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 involved_in
acts_upstream_of_or_within 		ISO
IEA
IBA 		(PMID:17671174)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000104
(PMID:17499941), (PMID:17671174)
GO_REF:0000033
GO_REF:0000041 		RGD
Ensembl
InterPro
UniProt
GO_Central		 PMID:17499941 PMID:17671174 GO_REF:0000002 GO_REF:0000033 GO_REF:0000041 GO_REF:0000104 GO_REF:0000107 NCBI chr16:67,459,158...67,498,052
Ensembl chr16:67,459,190...67,496,324 		JBrowse link
G Kynu kynureninase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000104
GO_REF:0000107
GO_REF:0000002
(PMID:27762317)
GO_REF:0000041 		UniProt
Ensembl
InterPro
RGD		 PMID:27762317 GO_REF:0000002 GO_REF:0000024 GO_REF:0000041 GO_REF:0000104 GO_REF:0000107 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511 		JBrowse link
L-tryptophan metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856102 (PMID:4147174) RGD PMID:4147174 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase IDA RGD PMID:10719243 PMID:3899109 PMID:3400092 RGD:2290190, RGD:2291804, RGD:2290313 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511 		JBrowse link
serotonin biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 IDA RGD PMID:23098818 RGD:11353778 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Tph1 tryptophan hydroxylase 1 TAS RGD PMID:12153488 RGD:625621 NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        indole-containing compound metabolic process 32
          indolalkylamine metabolic process 15
            L-tryptophan catabolic process to catechol 0
            L-tryptophan metabolic process + 13
            indolalkylamine biosynthetic process + 0
            nicotinate nucleotide biosynthetic process from tryptophan 0
            serotonin biosynthetic process from tryptophan 2
Path 2
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        amine metabolic process 127
          biogenic amine metabolic process 115
            indolalkylamine metabolic process 15
              L-tryptophan catabolic process to catechol 0
              L-tryptophan metabolic process + 13
              indolalkylamine biosynthetic process + 0
              nicotinate nucleotide biosynthetic process from tryptophan 0
              serotonin biosynthetic process from tryptophan 2
paths to the root