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ONTOLOGY REPORT - ANNOTATIONS


Term:glycoprotein catabolic process
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Accession:GO:0006516 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
Synonyms:exact_synonym: glycoprotein breakdown;   glycoprotein catabolism;   glycoprotein degradation



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glycoprotein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edem3 ER degradation enhancing alpha-mannosidase like protein 3 acts_upstream_of_or_within ISO (PMID:16431915) RGD PMID:16431915 NCBI chr13:63,858,282...63,920,538
Ensembl chr13:63,858,716...63,920,523
JBrowse link
G Fbxo17 F-box protein 17 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:84,002,276...84,024,455
Ensembl chr 1:84,002,267...84,024,453
JBrowse link
G Fbxo2 F-box protein 2 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:12140560)
(PMID:15723043)
GO_Central
RGD
PMID:12140560 PMID:15723043 GO_REF:0000033 NCBI chr 5:158,592,926...158,598,355
Ensembl chr 5:158,592,925...158,598,355
JBrowse link
G Fbxo27 F-box protein 27 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:83,965,426...83,987,781
Ensembl chr 1:83,965,986...83,987,778
JBrowse link
G Fbxo44 F-box protein 44 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:158,583,363...158,592,510
Ensembl chr 5:158,583,366...158,592,363
JBrowse link
G Fbxo6 F-box protein 6 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:15723043)
GO_Central
RGD
PMID:15723043 GO_REF:0000033 NCBI chr 5:163,859,909...163,865,693
Ensembl chr 5:158,576,759...158,582,525
JBrowse link
G Glb1 galactosidase, beta 1 involved_in ISO (PMID:31720227) RGD PMID:31720227 NCBI chr 8:122,963,718...123,036,326
Ensembl chr 8:114,085,508...114,158,127
JBrowse link
G Manba mannosidase beta involved_in
acts_upstream_of_or_within
ISS
ISO
IBA
GO_REF:0000024
(PMID:16377659)
(PMID:3447593)
GO_REF:0000033
UniProt
RGD
GO_Central
PMID:3447593 PMID:16377659 GO_REF:0000024 GO_REF:0000033 NCBI chr 2:226,583,968...226,676,520
Ensembl chr 2:223,910,432...224,002,983
JBrowse link
G Nccrp1 NCCRP1, F-box associated domain containing involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:83,835,083...83,838,620
Ensembl chr 1:83,835,083...83,838,676
JBrowse link
G Neu2 neuraminidase 2 involved_in ISO
IEA
(PMID:14613940)
GO_REF:0000107
RGD
Ensembl
PMID:14613940 GO_REF:0000107 NCBI chr 9:95,666,338...95,715,209
Ensembl chr 9:88,249,135...88,267,355
JBrowse link
G Neu4 neuraminidase 4 involved_in ISO (PMID:15213228), (PMID:15847605)
(PMID:19506080), (PMID:22393058)
RGD PMID:15213228 PMID:15847605 PMID:19506080 PMID:22393058 NCBI chr 9:101,844,261...101,849,917
Ensembl chr 9:94,396,920...94,402,576
JBrowse link
G Ngly1 N-glycanase 1 involved_in ISO
IBA
IEA
ISS
(PMID:15358861)
GO_REF:0000033
GO_REF:0000002
GO_REF:0000024
RGD
GO_Central
InterPro
UniProt
PMID:15358861 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 NCBI chr15:11,584,475...11,640,977
Ensembl chr15:9,153,738...9,204,630
JBrowse link
G Stt3b STT3 oligosaccharyltransferase complex catalytic subunit B involved_in ISO (PMID:22607976) RGD PMID:22607976 NCBI chr 8:114,928,678...114,994,027
Ensembl chr 8:114,917,824...114,994,028
JBrowse link
chondroitin sulfate proteoglycan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gusb glucuronidase, beta involved_in ISO MGI:1856041 (PMID:23897660) RGD PMID:23897660 NCBI chr12:32,337,281...32,350,838
Ensembl chr12:26,697,951...26,726,905
JBrowse link
G Hexb hexosaminidase subunit beta involved_in IEA
ISO
GO_REF:0000107
MGI:2429701 (PMID:22451654)
Ensembl
RGD
PMID:22451654 GO_REF:0000107 NCBI chr 2:30,218,608...30,238,771
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
G Hyal1 hyaluronidase 1 involved_in IEA
ISO
GO_REF:0000107
MGI:2658730 (PMID:22451654)
Ensembl
RGD
PMID:22451654 GO_REF:0000107 NCBI chr 8:117,129,311...117,133,162
Ensembl chr 8:108,250,667...108,260,210
JBrowse link
G Hyal4 hyaluronidase 4 acts_upstream_of_or_within ISO (PMID:23086929) RGD PMID:23086929 NCBI chr 4:53,256,179...53,274,819
Ensembl chr 4:53,256,179...53,274,819
JBrowse link
dermatan sulfate proteoglycan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arsb arylsulfatase B involved_in ISO MGI:3800577 (PMID:24240681) RGD PMID:24240681 NCBI chr 2:26,736,395...26,895,682
Ensembl chr 2:25,002,346...25,162,671
JBrowse link
G Hexa hexosaminidase subunit alpha involved_in ISO MGI:96074 (PMID:11707436) RGD PMID:11707436 NCBI chr 8:68,832,524...68,857,462
Ensembl chr 8:59,936,660...59,962,013
JBrowse link
G Hexb hexosaminidase subunit beta involved_in IEA
ISO
GO_REF:0000107
MGI:96073 (PMID:11707436)
Ensembl
RGD
PMID:11707436 GO_REF:0000107 NCBI chr 2:30,218,608...30,238,771
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
G Ids iduronate 2-sulfatase involved_in ISO MGI:5439833 (PMID:30064964) RGD PMID:30064964 NCBI chr  X:154,070,781...154,093,681
Ensembl chr  X:149,025,976...149,046,663
JBrowse link
G Idua alpha-L-iduronidase involved_in
acts_upstream_of_or_within
ISO (PMID:24036510)
MGI:2176236|MGI:4415188 (PMID:19751987), (PMID:25854773)
MGI:2176236|MGI:4415188 (PMID:19751987), (PMID:19834056)
RGD PMID:19751987 PMID:19834056 PMID:24036510 PMID:25854773 NCBI chr14:1,031,588...1,059,494
Ensembl chr14:1,032,171...1,046,522
JBrowse link
elastin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cela1 chymotrypsin like elastase 1 acts_upstream_of_or_within ISO (PMID:24793170) RGD PMID:24793170 NCBI chr 7:133,651,939...133,665,136
Ensembl chr 7:131,742,002...131,786,285
JBrowse link
G Ctsl cathepsin L involved_in ISS
ISO
GO_REF:0000024
(PMID:12417635)
UniProt
RGD
PMID:12417635 GO_REF:0000024 NCBI chr17:770,104...776,266
Ensembl chr17:764,309...770,548
JBrowse link
G Mmp12 matrix metallopeptidase 12 involved_in ISO
IEA
(PMID:29101312)
GO_REF:0000107
RGD
Ensembl
PMID:29101312 GO_REF:0000107 NCBI chr 8:12,866,652...12,876,554
Ensembl chr 8:4,581,785...4,599,611
JBrowse link
heparan sulfate proteoglycan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gns glucosamine (N-acetyl)-6-sulfatase involved_in ISO (PMID:15595925)
(PMID:33320673)
RGD PMID:15595925 PMID:33320673 NCBI chr 7:56,889,148...56,923,173
Ensembl chr 7:56,889,232...56,923,151
JBrowse link
G Gpc1 glypican 1 involved_in ISO
ISS
IEA
(PMID:12732622)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:12732622 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:100,843,645...100,871,458
Ensembl chr 9:93,396,234...93,424,047
JBrowse link
G Gusb glucuronidase, beta involved_in ISO MGI:1856041 (PMID:11273777), (PMID:23897660) RGD PMID:11273777 PMID:23897660 NCBI chr12:32,337,281...32,350,838
Ensembl chr12:26,697,951...26,726,905
JBrowse link
G Hgsnat heparan-alpha-glucosaminide N-acetyltransferase involved_in ISO UniProtKB:Q68CP4 (PMID:16960811), (PMID:27491071) RGD PMID:16960811 PMID:27491071 NCBI chr16:66,105,233...66,137,444
Ensembl chr16:66,105,181...66,136,138
JBrowse link
G Hpse heparanase involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:12460766)
(PMID:12213822)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:12213822 PMID:12460766 GO_REF:0000024 GO_REF:0000107 NCBI chr14:9,200,971...9,241,377
Ensembl chr14:8,896,593...8,937,010
JBrowse link
G Ids iduronate 2-sulfatase involved_in ISO MGI:3625122 (PMID:17876721) RGD PMID:17876721 NCBI chr  X:154,070,781...154,093,681
Ensembl chr  X:149,025,976...149,046,663
JBrowse link
G Idua alpha-L-iduronidase involved_in ISO MGI:2176236|MGI:2651471 (PMID:15979918), (PMID:25854773) RGD PMID:15979918 PMID:25854773 NCBI chr14:1,031,588...1,059,494
Ensembl chr14:1,032,171...1,046,522
JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase involved_in ISO MGI:1934018 (PMID:10588735) RGD PMID:10588735 NCBI chr10:86,501,864...86,509,333
Ensembl chr10:86,001,566...86,008,972
JBrowse link
G Sgsh N-sulfoglucosamine sulfohydrolase involved_in ISO
IBA
(PMID:15146460)
GO_REF:0000033
MGI:1856041|MGI:2151181 (PMID:10561464), (PMID:11273777)
RGD
GO_Central
PMID:10561464 PMID:11273777 PMID:15146460 GO_REF:0000033 NCBI chr10:104,596,810...104,613,510
Ensembl chr10:104,598,112...104,613,486
JBrowse link
heparin proteoglycan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idua alpha-L-iduronidase acts_upstream_of_or_within ISO (PMID:21873421)
MGI:2176236|MGI:4415188 (PMID:19751987), (PMID:19834056), (PMID:21873421)
RGD PMID:19751987 PMID:19834056 PMID:21873421 NCBI chr14:1,031,588...1,059,494
Ensembl chr14:1,032,171...1,046,522
JBrowse link
keratan sulfate proteoglycan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glb1 galactosidase, beta 1 involved_in ISO (PMID:31720227) RGD PMID:31720227 NCBI chr 8:122,963,718...123,036,326
Ensembl chr 8:114,085,508...114,158,127
JBrowse link
G Gns glucosamine (N-acetyl)-6-sulfatase IDA RGD PMID:3161730 RGD:1600571 NCBI chr 7:56,889,148...56,923,173
Ensembl chr 7:56,889,232...56,923,151
JBrowse link
mannoprotein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 involved_in ISO (PMID:25092655) RGD PMID:25092655 NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717
JBrowse link
G Edem2 ER degradation enhancing alpha-mannosidase like protein 2 involved_in ISO (PMID:25092655) RGD PMID:25092655 NCBI chr 3:144,201,604...144,227,423
Ensembl chr 3:144,201,605...144,227,485
JBrowse link
G Edem3 ER degradation enhancing alpha-mannosidase like protein 3 involved_in ISO
IBA
(PMID:25092655)
GO_REF:0000033
(PMID:16431915)
RGD
GO_Central
PMID:16431915 PMID:25092655 GO_REF:0000033 NCBI chr13:63,858,282...63,920,538
Ensembl chr13:63,858,716...63,920,523
JBrowse link
G Man1b1 mannosidase, alpha, class 1B, member 1 involved_in ISO (PMID:10521544), (PMID:18003979) RGD PMID:10521544 PMID:18003979 NCBI chr 3:28,539,778...28,563,155
Ensembl chr 3:8,143,381...8,165,006
JBrowse link
mannose trimming involved in glycoprotein ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Man1a1 mannosidase, alpha, class 1A, member 1 involved_in ISO (PMID:27108681) RGD PMID:27108681 NCBI chr20:33,745,158...33,928,584
Ensembl chr20:33,202,517...33,385,824
JBrowse link
negative regulation of elastin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst3 cystatin C involved_in ISO (PMID:10545518) RGD PMID:10545518 NCBI chr 3:156,790,061...156,794,116
Ensembl chr 3:136,336,920...136,340,822
JBrowse link
proteoglycan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 involved_in ISO (PMID:17895370) RGD PMID:17895370 NCBI chr 2:61,759,975...62,054,716
Ensembl chr 2:60,032,873...60,327,629
JBrowse link
G Btk Bruton tyrosine kinase IMP RGD PMID:32083858 RGD:151665122 NCBI chr  X:102,016,070...102,055,448
Ensembl chr  X:97,722,802...97,761,853
JBrowse link
ubiquitin-dependent glycoprotein ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edem3 ER degradation enhancing alpha-mannosidase like protein 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:63,858,282...63,920,538
Ensembl chr13:63,858,716...63,920,523
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20553
    cellular process 19543
      metabolic process 12181
        catabolic process 2922
          carbohydrate derivative catabolic process 310
            glycoprotein catabolic process 37
              O-sialoglycoprotein catabolic process 0
              elastin catabolic process + 4
              mannoprotein catabolic process 4
              protein deglycosylation involved in glycoprotein catabolic process + 1
              proteoglycan catabolic process + 17
              ubiquitin-dependent glycoprotein ERAD pathway + 2
Path 2
Term Annotations click to browse term
  biological_process 20553
    cellular process 19543
      metabolic process 12181
        macromolecule metabolic process 9999
          protein metabolic process 5230
            glycoprotein metabolic process 397
              glycoprotein catabolic process 37
                O-sialoglycoprotein catabolic process 0
                elastin catabolic process + 4
                mannoprotein catabolic process 4
                protein deglycosylation involved in glycoprotein catabolic process + 1
                proteoglycan catabolic process + 17
                ubiquitin-dependent glycoprotein ERAD pathway + 2
paths to the root