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ONTOLOGY REPORT - ANNOTATIONS

Term:signal peptide processing
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Accession:GO:0006465 term browser browse the term
Definition:The proteolytic removal of a signal peptide from a protein during or after transport to a specific location in the cell.
Synonyms:exact_synonym: leader peptide processing
 xref: Reactome:R-HSA-159782 "Removal of aminoterminal propeptides from gamma-carboxylated proteins"


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signal peptide processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arxes1 adipocyte-related X-chromosome expressed sequence 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:103,742,157...103,743,676
Ensembl chr  X:98,950,528...98,952,045 		JBrowse link
G Arxes2 adipocyte-related X-chromosome expressed sequence 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:103,777,456...103,779,036
Ensembl chr  X:98,985,959...98,986,501
Ensembl chr  X:98,985,959...98,986,501 		JBrowse link
G Cln5 CLN5, intracellular trafficking protein involved_in ISO (PMID:20052765) RGD PMID:20052765 NCBI chr15:86,308,286...86,321,679
Ensembl chr15:79,893,548...79,903,438
Ensembl chr 2:79,893,548...79,903,438 		JBrowse link
G ENSRNOG00000068334 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 Ensembl chr 4:102,869,248...102,869,735 JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) involved_in ISO
IEA		 (PMID:16912035)
GO_REF:0000107
(PMID:26416966)		 RGD
Ensembl		 PMID:16912035 PMID:26416966 GO_REF:0000107 NCBI chr 1:143,757,389...143,770,430
Ensembl chr 1:134,348,144...134,364,314 		JBrowse link
G Hm13 histocompatibility minor 13 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:161,606,059...161,641,382
Ensembl chr 3:141,145,782...141,184,703 		JBrowse link
G Immp1l inner mitochondrial membrane peptidase subunit 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:112,840,015...112,904,297
Ensembl chr 3:92,385,379...92,452,313 		JBrowse link
G Immp2l inner mitochondrial membrane peptidase subunit 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:63,797,189...64,696,906
Ensembl chr 6:58,070,283...58,969,840 		JBrowse link
G Mcts2 MCTS family member 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:161,623,597...161,624,375 JBrowse link
G Parl presenilin associated, rhomboid-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:94,097,559...94,124,915
Ensembl chr11:80,593,192...80,620,506 		JBrowse link
G Pcsk5 proprotein convertase subtilisin/kexin type 5 involved_in ISO (PMID:16912035) RGD PMID:16912035 NCBI chr 1:224,263,823...224,694,350
Ensembl chr 1:214,837,927...215,267,600 		JBrowse link
G Sec11a SEC11 homolog A, signal peptidase complex subunit involved_in ISO
IBA
IEA
ISS		 (PMID:34388369)
GO_REF:0000033
GO_REF:0000104
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:34388369 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 NCBI chr 1:144,290,680...144,318,658
Ensembl chr 1:134,875,265...134,915,069 		JBrowse link
G Sec11c SEC11 homolog C, signal peptidase complex subunit involved_in IEA
IBA
ISS
ISO		 GO_REF:0000104
GO_REF:0000033
GO_REF:0000002
GO_REF:0000024
(PMID:34388369)		 UniProt
GO_Central
InterPro
RGD		 PMID:34388369 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 NCBI chr18:61,590,905...61,607,247
Ensembl chr18:59,320,884...59,337,364 		JBrowse link
G Spcs1 signal peptidase complex subunit 1 involved_in ISO
IBA		 (PMID:34388369)
GO_REF:0000033		 RGD
GO_Central		 PMID:34388369 GO_REF:0000033 NCBI chr16:6,196,653...6,198,221
Ensembl chr16:6,190,262...6,192,000 		JBrowse link
G Spcs2 signal peptidase complex subunit 2 involved_in ISO
IBA		 (PMID:34388369)
GO_REF:0000033		 RGD
GO_Central		 PMID:34388369 GO_REF:0000033 NCBI chr 1:163,575,842...163,595,269
Ensembl chr 1:154,163,724...154,183,186 		JBrowse link
G Spcs3 signal peptidase complex subunit 3 involved_in ISO
IBA		 (PMID:34388369)
GO_REF:0000033		 RGD
GO_Central		 PMID:34388369 GO_REF:0000033 NCBI chr16:44,038,421...44,043,855
Ensembl chr16:37,305,305...37,331,746 		JBrowse link
G Sppl3 signal peptide peptidase like 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:47,176,317...47,260,756
Ensembl chr12:41,515,640...41,600,126 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20546
    cellular process 19536
      metabolic process 12171
        macromolecule metabolic process 9985
          protein metabolic process 5215
            protein maturation 628
              protein processing 260
                signal peptide processing 17
                  SRP-dependent cotranslational protein targeting to membrane, signal sequence processing 0
Path 2
Term Annotations click to browse term
  biological_process 20546
    cellular process 19536
      metabolic process 12171
        biosynthetic process 8663
          macromolecule biosynthetic process 7656
            gene expression 7232
              protein maturation 628
                protein processing 260
                  signal peptide processing 17
                    SRP-dependent cotranslational protein targeting to membrane, signal sequence processing 0
paths to the root