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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of translational initiation
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Accession:GO:0006446 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of translational initiation.


show annotations for term's descendants           Sort by:
regulation of translational initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh1 alkB homolog 1, histone H2A dioxygenase involved_in ISO
IEA 		(PMID:27745969)
GO_REF:0000107 		RGD
Ensembl		 PMID:27745969 GO_REF:0000107 NCBI chr 6:107,068,301...107,088,784
Ensembl chr 6:107,068,475...107,088,759 		JBrowse link
G Bc1 brain cytoplasmic RNA 1 IDA RGD PMID:12451124 RGD:628491 NCBI chr 1:200,073,610...200,073,763 JBrowse link
G Bzw1 basic leucine zipper and W2 domains 1 involved_in ISO
IEA
ISS 		(PMID:29470543), (PMID:34260931)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:29470543 PMID:34260931 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:59,930,672...59,944,468
Ensembl chr 9:59,930,744...59,944,430 		JBrowse link
G Bzw2 basic leucine zipper and W2 domains 2 involved_in ISO
IEA
ISS 		(PMID:21745818), (PMID:28981728), (PMID:29470543), (PMID:34260931)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:21745818 PMID:28981728 PMID:29470543 PMID:34260931 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:52,828,069...52,888,599
Ensembl chr 6:52,827,661...52,888,628 		JBrowse link
G Ctif cap binding complex dependent translation initiation factor involved_in ISO
IEA
IBA 		(PMID:19648179)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:19648179 GO_REF:0000033 GO_REF:0000107 NCBI chr18:69,056,151...69,327,454
Ensembl chr18:69,059,519...69,327,385 		JBrowse link
G Eif1 eukaryotic translation initiation factor 1 involved_in ISO (PMID:22156057) RGD PMID:22156057 NCBI chr10:85,246,751...85,248,842
Ensembl chr10:85,246,764...85,427,327
Ensembl chr 5:85,246,764...85,427,327 		JBrowse link
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:10,710,771...10,744,597
Ensembl chr12:10,705,874...10,744,573 		JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISO
IBA 		(PMID:14729979)
GO_REF:0000033 		RGD
GO_Central		 PMID:14729979 GO_REF:0000033 NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISO UniProtKB:Q9Z2B5 (PMID:14729979) RGD PMID:14729979 NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630 		JBrowse link
G Eif3b eukaryotic translation initiation factor 3, subunit B involved_in ISO
IEA
ISS 		(PMID:8995410)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:8995410 GO_REF:0000024 GO_REF:0000107 NCBI chr12:14,196,403...14,220,865
Ensembl chr12:14,196,403...14,220,886 		JBrowse link
G Eif3k eukaryotic translation initiation factor 3, subunit K involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:84,260,127...84,270,051
Ensembl chr 1:84,259,673...84,270,302 		JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma 1 involved_in ISO (PMID:19648179) RGD PMID:19648179 NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941 		JBrowse link
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 involved_in ISO (PMID:11943866)
(PMID:9030685) 		RGD PMID:9030685 PMID:11943866 NCBI chr 1:174,616,102...174,628,252
Ensembl chr 1:165,181,434...165,193,588 		JBrowse link
G Eif5 eukaryotic translation initiation factor 5 involved_in ISO (PMID:22156057) RGD PMID:22156057 NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656 		JBrowse link
G Eif5b eukaryotic translation initiation factor 5B involved_in ISO (PMID:10432305) RGD PMID:10432305 NCBI chr 9:40,222,769...40,277,482
Ensembl chr 9:40,222,898...40,277,482 		JBrowse link
G ENSRNOG00000064097 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr14:101,092,526...101,094,482 JBrowse link
G Impact impact RWD domain protein involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
(PMID:15937339) 		GO_Central
RGD		 PMID:15937339 GO_REF:0000033 NCBI chr18:4,108,872...4,147,571
Ensembl chr18:4,108,853...4,147,569 		JBrowse link
G Klhl25 kelch-like family member 25 involved_in ISO
ISS 		(PMID:22578813)
GO_REF:0000024 		RGD
UniProt		 PMID:22578813 GO_REF:0000024 NCBI chr 1:129,724,894...129,750,142
Ensembl chr 1:129,722,026...129,750,227 		JBrowse link
G Metap2 methionyl aminopeptidase 2 involved_in ISS
ISO 		GO_REF:0000024
(PMID:8858118) 		HGNC-UCL
RGD		 PMID:8858118 GO_REF:0000024 NCBI chr 7:28,412,429...28,440,458
Ensembl chr 7:28,411,608...28,440,434 		JBrowse link
G Mif4gd MIF4G domain containing involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:100,847,168...100,852,166 JBrowse link
G Mknk1 MAPK interacting serine/threonine kinase 1 IMP RGD PMID:17510413 PMID:16955078 RGD:8553009, RGD:8553011 NCBI chr 5:129,318,128...129,357,641
Ensembl chr 5:129,318,170...129,357,639 		JBrowse link
G Ncbp1 nuclear cap binding protein subunit 1 involved_in ISO
IEA
ISS 		(PMID:11551508)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:11551508 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:60,416,023...60,449,004
Ensembl chr 5:60,415,982...60,449,089 		JBrowse link
G Ncbp2 nuclear cap binding protein subunit 2 involved_in ISO
IEA 		(PMID:11551508)
GO_REF:0000107 		RGD
Ensembl		 PMID:11551508 GO_REF:0000107 NCBI chr11:68,821,026...68,829,863
Ensembl chr11:68,817,740...68,851,885 		JBrowse link
G Paip1 poly(A) binding protein interacting protein 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:51,523,190...51,550,241
Ensembl chr 2:51,522,921...51,550,241 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A involved_in ISO (PMID:11564868) RGD PMID:11564868 NCBI chr 1:105,136,521...105,139,596
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
eiF2alpha phosphorylation in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISO (PMID:17707796) RGD PMID:17707796 NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
negative regulation of cytoplasmic translational initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hhex hematopoietically expressed homeobox involved_in ISO (PMID:12554669) RGD PMID:12554669 NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042 		JBrowse link
negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 involved_in ISS
ISO 		GO_REF:0000024
(PMID:25329545) 		UniProt
RGD		 PMID:25329545 GO_REF:0000024 NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181 		JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 acts_upstream_of_or_within ISO MGI:4456438 (PMID:28797121) RGD PMID:28797121 NCBI chr12:32,052,542...32,061,628
Ensembl chr12:32,052,543...32,071,903 		JBrowse link
negative regulation of formation of translation preinitiation complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpl13a ribosomal protein L13A involved_in ISO
IEA
ISS 		(PMID:17218275)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:17218275 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:95,609,374...95,612,557
Ensembl chr 1:95,609,370...95,620,463 		JBrowse link
negative regulation of translation in response to oxidative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pml PML nuclear body scaffold involved_in ISO (PMID:16915281) RGD PMID:16915281 NCBI chr 8:67,523,164...67,557,801
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
negative regulation of translational initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ago2 argonaute RISC catalytic component 2 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:17524464), (PMID:19801630)
GO_REF:0000104 		UniProt
Ensembl
RGD		 PMID:17524464 PMID:19801630 GO_REF:0000024 GO_REF:0000104 GO_REF:0000107 NCBI chr 7:105,018,202...105,105,118
Ensembl chr 7:105,029,120...105,104,974 		JBrowse link
G Bank1 B-cell scaffold protein with ankyrin repeats 1 acts_upstream_of_or_within ISO
IEA 		MGI:3686872 (PMID:24227780)
GO_REF:0000107 		RGD
Ensembl		 PMID:24227780 GO_REF:0000107 NCBI chr 2:224,530,475...224,800,420
Ensembl chr 2:224,530,475...224,800,405 		JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISS
ISO 		GO_REF:0000024
(PMID:16601681) 		UniProt
RGD		 PMID:16601681 GO_REF:0000024 NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630 		JBrowse link
G Eif4e2 eukaryotic translation initiation factor 4E family member 2 involved_in ISO
IEA 		(PMID:32726578), (PMID:35878012)
GO_REF:0000107 		RGD
Ensembl		 PMID:32726578 PMID:35878012 GO_REF:0000107 NCBI chr 9:87,886,126...87,914,470
Ensembl chr 9:87,878,085...87,914,482 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 involved_in
acts_upstream_of_or_within 		IMP
IEA
ISO
IBA 		GO_REF:0000002
(PMID:16142217)
GO_REF:0000033
GO_REF:0000117
(PMID:22578813) 		InterPro
RGD
GO_Central
UniProt		 PMID:16142217 PMID:22578813 PMID:11865047 GO_REF:0000002 GO_REF:0000033 GO_REF:0000117, RGD:1625627 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Eif4ebp2 eukaryotic translation initiation factor 4E binding protein 2 involved_in ISO
IEA
IBA 		(PMID:30765518)
GO_REF:0000107
GO_REF:0000117
GO_REF:0000002
(PMID:16237163), (PMID:20347422), (PMID:23172145)
GO_REF:0000033 		RGD
Ensembl
UniProt
InterPro
GO_Central		 PMID:16237163 PMID:20347422 PMID:23172145 PMID:30765518 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr20:29,379,444...29,400,110
Ensembl chr20:29,382,668...29,399,946 		JBrowse link
G Eif4ebp3 eukaryotic translation initiation factor 4E binding protein 3 involved_in IEA GO_REF:0000117
GO_REF:0000002 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000117 NCBI chr18:28,263,089...28,268,033
Ensembl chr18:28,162,311...28,268,024 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:18805096) 		UniProt
RGD		 PMID:18805096 GO_REF:0000024 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050 		JBrowse link
G Gigyf2 GRB10 interacting GYF protein 2 involved_in ISO
IEA 		(PMID:32726578), (PMID:35878012)
GO_REF:0000107 		RGD
Ensembl		 PMID:32726578 PMID:35878012 GO_REF:0000107 NCBI chr 9:88,001,212...88,127,040
Ensembl chr 9:88,001,301...88,125,715 		JBrowse link
G Larp1 La ribonucleoprotein 1, translational regulator involved_in ISO
IEA 		(PMID:28379136)
GO_REF:0000107 		RGD
Ensembl		 PMID:28379136 GO_REF:0000107 NCBI chr10:42,191,378...42,246,361
Ensembl chr10:42,191,325...42,243,371 		JBrowse link
G Paip2 poly(A) binding protein interacting protein 2 involved_in ISO
IEA 		(PMID:11172725)
GO_REF:0000002 		RGD
InterPro		 PMID:11172725 GO_REF:0000002 NCBI chr18:27,199,762...27,218,359
Ensembl chr18:27,199,796...27,214,863
Ensembl chr 1:27,199,796...27,214,863 		JBrowse link
G Paip2b poly(A) binding protein interacting protein 2B involved_in ISO
IEA 		(PMID:16804161)
GO_REF:0000002 		RGD
InterPro		 PMID:16804161 GO_REF:0000002 NCBI chr 4:116,292,001...116,323,387
Ensembl chr 4:116,292,020...116,323,379 		JBrowse link
G Rbm14 RNA binding motif protein 14 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 1:202,076,940...202,105,688
Ensembl chr 1:202,078,287...202,105,665
Ensembl chr 1:202,078,287...202,105,665 		JBrowse link
G Rbm4 RNA binding motif protein 4 involved_in ISO (PMID:19801630) RGD PMID:19801630 NCBI chr 1:202,078,442...202,087,506
Ensembl chr 1:202,085,279...202,105,380 		JBrowse link
G Scrib scribble planar cell polarity protein involved_in ISO (PMID:34535749) RGD PMID:34535749 NCBI chr 7:107,759,343...107,782,364
Ensembl chr 7:107,759,343...107,782,331 		JBrowse link
G Tpr translocated promoter region, nuclear basket protein involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:21613532) 		UniProt
Ensembl
RGD		 PMID:21613532 GO_REF:0000024 GO_REF:0000107 NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496 		JBrowse link
G Zfp598 zinc finger protein 598 involved_in ISO (PMID:28065601) RGD PMID:28065601 NCBI chr10:14,198,763...14,210,773
Ensembl chr10:13,694,286...13,706,233 		JBrowse link
negative regulation of translational initiation in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISO
IBA 		(PMID:12176355)
GO_REF:0000033 		RGD
GO_Central		 PMID:12176355 GO_REF:0000033 NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:12176355) 		UniProt
Ensembl
RGD		 PMID:12176355 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
positive regulation of cap-dependent translational initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt2 AKT serine/threonine kinase 2 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:23444369) 		UniProt
Ensembl
RGD		 PMID:23444369 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO
IEA 		(PMID:11959995)
GO_REF:0000107 		RGD
Ensembl		 PMID:11959995 GO_REF:0000107 NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300 		JBrowse link
G Pkp1 plakophilin 1 involved_in ISO
IEA 		(PMID:23444369)
GO_REF:0000107 		RGD
Ensembl		 PMID:23444369 GO_REF:0000107 NCBI chr13:47,309,607...47,357,432
Ensembl chr13:47,309,614...47,357,465 		JBrowse link
positive regulation of cap-independent translational initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mettl3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit involved_in ISO
IEA 		(PMID:26593424)
GO_REF:0000107 		RGD
Ensembl		 PMID:26593424 GO_REF:0000107 NCBI chr15:25,002,505...25,014,097
Ensembl chr15:25,003,172...25,014,041 		JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO
IEA 		(PMID:11959995)
GO_REF:0000107 		RGD
Ensembl		 PMID:11959995 GO_REF:0000107 NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300 		JBrowse link
G Ythdf2 YTH N6-methyladenosine RNA binding protein F2 involved_in ISO (PMID:26458103) RGD PMID:26458103 NCBI chr 5:144,381,426...144,407,126
Ensembl chr 5:144,381,431...144,408,144 		JBrowse link
positive regulation of cytoplasmic translational initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sh3bgrl1 SH3 domain binding glutamate rich protein like 1 involved_in ISO (PMID:34331014) RGD PMID:34331014 NCBI chr  X:74,167,029...74,263,783
Ensembl chr  X:74,166,871...74,263,783 		JBrowse link
positive regulation of translation initiation in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 involved_in ISS
ISO 		GO_REF:0000024
(PMID:25329545) 		UniProt
RGD		 PMID:25329545 GO_REF:0000024 NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181 		JBrowse link
positive regulation of translational initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Boll boule homolog, RNA binding protein involved_in ISO
IEA
IBA 		(PMID:16001084)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:16001084 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:56,734,890...56,859,917
Ensembl chr 9:56,733,584...56,859,916 		JBrowse link
G Dazl deleted in azoospermia-like involved_in ISO
IEA
IBA 		(PMID:16001084)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:16001084 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:10,695,593...10,712,330
Ensembl chr 9:10,695,592...10,712,323 		JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:20837705) RGD PMID:20837705 NCBI chr  X:9,479,532...9,493,169
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Dhx29 DExH-box helicase 29 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 2:44,560,653...44,611,450
Ensembl chr 2:44,560,714...44,611,445 		JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr11:80,394,433...80,404,468
Ensembl chr11:80,394,433...80,404,419 		JBrowse link
G Habp4 hyaluronan binding protein 4 involved_in ISO
IEA
IBA
ISS 		(PMID:21771594)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000024 		RGD
Ensembl
GO_Central
UniProt		 PMID:21771594 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr17:940,672...963,358
Ensembl chr17:935,654...957,565 		JBrowse link
G Khdrbs1 KH RNA binding domain containing, signal transduction associated 1 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:21613532) 		UniProt
Ensembl
RGD		 PMID:21613532 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:142,051,844...142,089,175
Ensembl chr 5:142,063,570...142,089,180 		JBrowse link
G Larp1 La ribonucleoprotein 1, translational regulator involved_in ISO
IEA 		(PMID:29244122)
GO_REF:0000107 		RGD
Ensembl		 PMID:29244122 GO_REF:0000107 NCBI chr10:42,191,378...42,246,361
Ensembl chr10:42,191,325...42,243,371 		JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in IEA
ISO 		GO_REF:0000107
(PMID:22578813), (PMID:29750193) 		Ensembl
RGD		 PMID:22578813 PMID:29750193 GO_REF:0000107 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Polr2g RNA polymerase II subunit G involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:205,689,160...205,692,537
Ensembl chr 1:205,689,160...205,692,686 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 involved_in ISO (PMID:16763566), (PMID:1922062) RGD PMID:1922062 PMID:16763566 NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,323,777...71,367,908 		JBrowse link
G Rps6kb2 ribosomal protein S6 kinase B2 involved_in ISO
IEA 		(PMID:16763566), (PMID:29750193)
GO_REF:0000107 		RGD
Ensembl		 PMID:16763566 PMID:29750193 GO_REF:0000107 NCBI chr 1:201,451,265...201,458,096
Ensembl chr 1:201,451,265...201,458,078 		JBrowse link
G Uhmk1 U2AF homology motif kinase 1 involved_in IBA
ISO 		GO_REF:0000033
(PMID:19015237) 		GO_Central
RGD		 PMID:19015237 GO_REF:0000033 NCBI chr13:82,396,646...82,416,292
Ensembl chr13:82,401,187...82,416,292 		JBrowse link
G Ythdf1 YTH N6-methyladenosine RNA binding protein F1 NOT|involved_in ISO (PMID:32492408)
(PMID:32943573)
(PMID:26046440) 		RGD PMID:26046440 PMID:32492408 PMID:32943573 NCBI chr 3:168,024,660...168,040,172
Ensembl chr 3:168,024,663...168,040,172 		JBrowse link
G Ythdf2 YTH N6-methyladenosine RNA binding protein F2 NOT|involved_in ISO (PMID:32492408)
(PMID:32943573) 		RGD PMID:32492408 PMID:32943573 NCBI chr 5:144,381,426...144,407,126
Ensembl chr 5:144,381,431...144,408,144 		JBrowse link
G Ythdf3 YTH N6-methyladenosine RNA binding protein F3 NOT|involved_in ISO (PMID:32492408)
(PMID:32943573)
(PMID:28106076) 		RGD PMID:28106076 PMID:32492408 PMID:32943573 NCBI chr 2:98,350,304...98,384,608
Ensembl chr 2:98,350,588...98,384,606 		JBrowse link
positive regulation of translational initiation by iron term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rxra retinoid X receptor alpha acts_upstream_of_or_within ISO MGI:1201686 (PMID:23775127) RGD PMID:23775127 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO (PMID:11588035) RGD PMID:11588035 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
positive regulation of translational initiation in response to starvation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISS
ISO 		GO_REF:0000024
(PMID:10655230), (PMID:16121183) 		UniProt
RGD		 PMID:10655230 PMID:16121183 GO_REF:0000024 NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630 		JBrowse link
positive regulation of translational initiation in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A involved_in ISO (PMID:12556489) RGD PMID:12556489 NCBI chr 1:105,136,521...105,139,596
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
regulation of cytoplasmic translational initiation in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISO (PMID:24333428) RGD PMID:24333428 NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630 		JBrowse link
G Impact impact RWD domain protein involved_in ISS
ISO 		GO_REF:0000024
(PMID:24333428) 		UniProt
RGD		 PMID:24333428 GO_REF:0000024 NCBI chr18:4,108,872...4,147,571
Ensembl chr18:4,108,853...4,147,569 		JBrowse link
regulation of eIF2 alpha phosphorylation by dsRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Npm1 nucleophosmin 1 involved_in ISO
ISS 		(PMID:12882984)
GO_REF:0000024 		RGD
UniProt		 PMID:12882984 GO_REF:0000024 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
Ensembl chr  X:17,739,941...17,751,645 		JBrowse link
regulation of eIF2 alpha phosphorylation by heme term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 acts_upstream_of_or_within ISO MGI:1353448|MGI:95513 (PMID:15931390) RGD PMID:15931390 NCBI chr12:10,710,771...10,744,597
Ensembl chr12:10,705,874...10,744,573 		JBrowse link
G Fech ferrochelatase acts_upstream_of_or_within ISO MGI:1353448|MGI:1858114|MGI:95513 (PMID:15931390) RGD PMID:15931390 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348 		JBrowse link
G Hbb hemoglobin subunit beta acts_upstream_of_or_within ISO MGI:1857179 (PMID:15931390) RGD PMID:15931390 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISS
ISO 		GO_REF:0000024
(PMID:11106749) 		UniProt
RGD		 PMID:11106749 GO_REF:0000024 NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
regulation of translation initiation in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISO (PMID:14676213) RGD PMID:14676213 NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Nck1 NCK adaptor protein 1 involved_in IEA
ISO 		GO_REF:0000107
UniProtKB:O55033 (PMID:14676213) 		Ensembl
RGD		 PMID:14676213 GO_REF:0000107 NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300 		JBrowse link
G Nck2 NCK adaptor protein 2 involved_in IEA
ISO 		GO_REF:0000107
UniProtKB:Q99M51 (PMID:14676213) 		Ensembl
RGD		 PMID:14676213 GO_REF:0000107 NCBI chr 9:45,713,979...45,840,330
Ensembl chr 9:45,714,883...45,840,307 		JBrowse link
regulation of translational initiation by eIF2 alpha phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISO (PMID:11106749) RGD PMID:11106749 NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISS
ISO 		GO_REF:0000024
(PMID:10655230), (PMID:11106749), (PMID:12176355), (PMID:16121183), (PMID:16601681), (PMID:26102367)
(PMID:26102367) 		UniProt
RGD		 PMID:10655230 PMID:11106749 PMID:12176355 PMID:16121183 PMID:16601681 More... GO_REF:0000024 NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630 		JBrowse link
regulation of translational initiation by tRNA modification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh1 alkB homolog 1, histone H2A dioxygenase involved_in ISO
IEA 		(PMID:27745969)
GO_REF:0000107 		RGD
Ensembl		 PMID:27745969 GO_REF:0000107 NCBI chr 6:107,068,301...107,088,784
Ensembl chr 6:107,068,475...107,088,759 		JBrowse link
regulation of translational initiation in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISO (PMID:10882126) RGD PMID:10882126 NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 acts_upstream_of_or_within ISO (PMID:15937339) RGD PMID:15937339 NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha acts_upstream_of_or_within ISO
IEA 		(PMID:15937339)
GO_REF:0000107 		RGD
Ensembl		 PMID:15937339 GO_REF:0000107 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A involved_in ISO (PMID:11564868)
(PMID:11381086) 		RGD PMID:11381086 PMID:11564868 NCBI chr 1:105,136,521...105,139,596
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        translational initiation 138
          regulation of translational initiation 75
            negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation 2
            negative regulation of translational initiation + 22
            positive regulation of translational initiation + 26
            regulation of cytoplasmic translational initiation + 10
            regulation of eIF2 alpha phosphorylation by dsRNA 1
            regulation of eIF2 alpha phosphorylation by heme 3
            regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation 1
            regulation of mitochondrial translational initiation + 0
            regulation of translational initiation by iron + 2
            regulation of translational initiation by tRNA modification 1
            regulation of translational initiation in response to stress + 14
Path 2
Term Annotations click to browse term
  biological_process 20543
    biological regulation 13835
      regulation of biological process 13398
        regulation of cellular process 13032
          regulation of metabolic process 6776
            regulation of macromolecule metabolic process 6244
              regulation of macromolecule biosynthetic process 5373
                regulation of gene expression 5256
                  post-transcriptional regulation of gene expression 766
                    regulation of translation 483
                      regulation of translational initiation 75
                        negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation 2
                        negative regulation of translational initiation + 22
                        positive regulation of translational initiation + 26
                        regulation of cytoplasmic translational initiation + 10
                        regulation of eIF2 alpha phosphorylation by dsRNA 1
                        regulation of eIF2 alpha phosphorylation by heme 3
                        regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation 1
                        regulation of mitochondrial translational initiation + 0
                        regulation of translational initiation by iron + 2
                        regulation of translational initiation by tRNA modification 1
                        regulation of translational initiation in response to stress + 14
paths to the root