ONTOLOGY REPORT - ANNOTATIONS
Term: 'de novo' pyrimidine nucleobase biosynthetic process
Accession: GO:0006207
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Definition: The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases, beginning with the synthesis of a pyrimidine ring from simpler precursors.
Synonyms: exact_synonym: 'de novo' pyrimidine base anabolism; 'de novo' pyrimidine base biosynthesis; 'de novo' pyrimidine base biosynthetic process; 'de novo' pyrimidine base formation; 'de novo' pyrimidine base synthesis
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Cad
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
involved_in
IDA ISO IBA IEA
(PMID:24332717) GO_REF:0000033 GO_REF:0000002 GO_REF:0000107
RGD GO_Central InterPro Ensembl
PMID:24332717 PMID:1476792
GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:5132591
NCBI chr 6:31,012,091...31,035,098
Ensembl chr 6:25,292,133...25,319,861
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Cmpk1
cytidine/uridine monophosphate kinase 1
involved_in
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr 5:133,717,073...133,744,623
Ensembl chr 5:128,480,301...128,507,830
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Cps1
carbamoyl-phosphate synthase 1
involved_in
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr 9:76,063,863...76,186,739
Ensembl chr 9:68,614,153...68,737,033
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Dhodh
dihydroorotate dehydrogenase
involved_in
IDA IEA IBA
GO_REF:0000002 GO_REF:0000033
InterPro GO_Central RGD
PMID:1476792
GO_REF:0000002 GO_REF:0000033, RGD:5132591
NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654
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Mtor
mechanistic target of rapamycin kinase
involved_in
IEA ISO
GO_REF:0000107 (PMID:23429704)
Ensembl RGD
PMID:23429704
GO_REF:0000107
NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:158,884,804...158,994,311
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Umps
uridine monophosphate synthetase
involved_in
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr11:66,806,107...66,816,520
Ensembl chr11:66,806,045...66,821,903
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