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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of gluconeogenesis
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Accession:GO:0006111 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
Synonyms:broad_synonym: regulation of glucose biosynthesis;   regulation of glucose biosynthetic process
 related_synonym: regulation of gluconeogenesis involved in cellular glucose homeostasis
 alt_id: GO:0090526


show annotations for term's descendants           Sort by:
regulation of gluconeogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadm acyl-CoA dehydrogenase medium chain involved_in IEA
ISO 		GO_REF:0000107
(PMID:18459129) 		Ensembl
RGD		 PMID:18459129 GO_REF:0000107 NCBI chr 2:245,518,693...245,542,864
Ensembl chr 2:242,858,865...242,883,147 		JBrowse link
G Cry1 cryptochrome circadian regulator 1 involved_in ISO (PMID:29937374) RGD PMID:29937374 NCBI chr 7:20,417,526...20,481,791
Ensembl chr 7:18,529,823...18,594,091 		JBrowse link
G Dgkq diacylglycerol kinase, theta involved_in ISO (PMID:23767959) RGD PMID:23767959 NCBI chr14:1,059,125...1,073,131
Ensembl chr14:1,059,170...1,073,131 		JBrowse link
G Fbp1 fructose-bisphosphatase 1 involved_in ISO
ISS
IEA 		(PMID:7558035)
GO_REF:0000024
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:7558035 GO_REF:0000024 GO_REF:0000107 NCBI chr17:2,212,941...2,235,749
Ensembl chr17:2,208,031...2,230,071 		JBrowse link
G Foxo1 forkhead box O1 acts_upstream_of_or_within ISO
IEA 		(PMID:18497885)
GO_REF:0000107 		RGD
Ensembl		 PMID:18497885 GO_REF:0000107 NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Gnmt glycine N-methyltransferase involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
MGI:3842652 (PMID:17937387) 		GO_Central
RGD		 PMID:17937387 GO_REF:0000033 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434 		JBrowse link
G Insr insulin receptor IEP RGD PMID:29896241 RGD:14700925 NCBI chr12:5,991,135...6,129,275
Ensembl chr12:1,197,100...1,330,883 		JBrowse link
G Lep leptin acts_upstream_of_or_within ISO
IEA 		MGI:1856424 (PMID:16513828)
GO_REF:0000107 		RGD
Ensembl		 PMID:16513828 GO_REF:0000107 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Nln neurolysin acts_upstream_of_or_within ISO MGI:4125183 (PMID:24719317) RGD PMID:24719317 NCBI chr 2:35,133,634...35,232,927
Ensembl chr 2:35,134,145...35,232,914 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 acts_upstream_of_or_within ISO
IEA 		MGI:1857745 (PMID:7628695)
GO_REF:0000107 		RGD
Ensembl		 PMID:7628695 GO_REF:0000107 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IEA
ISO
ISS 		GO_REF:0000107
(PMID:23395176)
GO_REF:0000024 		Ensembl
RGD
UniProt		 PMID:23395176 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:70,811,317...70,856,123
Ensembl chr  X:66,771,349...66,816,146 		JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 involved_in ISS
ISO 		GO_REF:0000024
(PMID:22360721) 		UniProt
RGD		 PMID:22360721 GO_REF:0000024 NCBI chr10:79,972,550...79,987,074
Ensembl chr10:79,972,556...79,987,085 		JBrowse link
G Ranbp2 RAN binding protein 2 acts_upstream_of_or_within ISO
IEA 		MGI:3693886 (PMID:17069463)
GO_REF:0000107 		RGD
Ensembl		 PMID:17069463 GO_REF:0000107 NCBI chr20:26,442,156...26,493,481
Ensembl chr20:26,442,217...26,493,481 		JBrowse link
G Sesn2 sestrin 2 acts_upstream_of_or_within ISO
IEA 		MGI:3587950 (PMID:22958918)
GO_REF:0000107 		RGD
Ensembl		 PMID:22958918 GO_REF:0000107 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260 		JBrowse link
G Slc35b4 solute carrier family 35 member B4 acts_upstream_of_or_within ISO
IEA 		(PMID:21507882)
GO_REF:0000107 		RGD
Ensembl		 PMID:21507882 GO_REF:0000107 NCBI chr 4:62,776,993...62,799,013
Ensembl chr 4:62,776,993...62,799,003 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 acts_upstream_of_or_within ISO MGI:4431951 (PMID:23028378) RGD PMID:23028378 NCBI chr 1:264,791,335...264,984,225
Ensembl chr 1:254,786,091...254,978,967 		JBrowse link
G Zfp692 zinc finger protein 692 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:21910974) 		UniProt
Ensembl
RGD		 PMID:21910974 GO_REF:0000024 GO_REF:0000107 NCBI chr10:42,484,576...42,496,573
Ensembl chr10:42,488,588...42,496,018 		JBrowse link
negative regulation of gluconeogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing involved_in
acts_upstream_of_or_within 		ISS
ISO 		GO_REF:0000024
(PMID:11479628) 		UniProt
RGD		 PMID:11479628 GO_REF:0000024 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G C1qtnf12 C1q and TNF related 12 involved_in
acts_upstream_of_or_within 		IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
(PMID:22275362) 		GO_Central
Ensembl
RGD		 PMID:22275362 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:166,551,628...166,556,003
Ensembl chr 5:166,551,628...166,556,003 		JBrowse link
G C1qtnf3 C1q and TNF related 3 acts_upstream_of_or_within
involved_in 		ISO
IEA 		(PMID:20952387)
GO_REF:0000107 		RGD
Ensembl		 PMID:20952387 GO_REF:0000107 NCBI chr 2:59,917,099...59,939,519
Ensembl chr 2:59,917,188...59,939,433 		JBrowse link
G Clk2 CDC-like kinase 2 involved_in ISO (PMID:20074525) RGD PMID:20074525 NCBI chr 2:174,570,614...174,582,645
Ensembl chr 2:174,570,653...174,588,985 		JBrowse link
G Cry1 cryptochrome circadian regulator 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:28790135), (PMID:29937374) 		UniProt
RGD		 PMID:28790135 PMID:29937374 GO_REF:0000024 NCBI chr 7:20,417,526...20,481,791
Ensembl chr 7:18,529,823...18,594,091 		JBrowse link
G Ep300 E1A binding protein p300 involved_in ISO (PMID:30193097) RGD PMID:30193097 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Erfe erythroferrone involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:99,404,512...99,412,383
Ensembl chr 9:91,956,977...91,964,846 		JBrowse link
G Gck glucokinase involved_in ISO
IEA
ISS 		(PMID:8878425)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:8878425 GO_REF:0000024 GO_REF:0000107 NCBI chr14:84,999,019...85,041,098
Ensembl chr14:80,785,060...80,826,995 		JBrowse link
G Il6 interleukin 6 IDA In liver RGD PMID:16308834 RGD:2306940 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ins2 insulin 2 involved_in ISO (PMID:8069456) RGD PMID:8069456 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Kat2a lysine acetyltransferase 2A involved_in ISO
IEA 		(PMID:16753578), (PMID:23142079)
GO_REF:0000107 		RGD
Ensembl		 PMID:16753578 PMID:23142079 GO_REF:0000107 NCBI chr10:86,132,535...86,140,877
Ensembl chr10:85,632,216...85,640,166 		JBrowse link
G Lepr leptin receptor acts_upstream_of_or_within ISO
IEA 		MGI:1856009 (PMID:24051374)
GO_REF:0000107 		RGD
Ensembl		 PMID:24051374 GO_REF:0000107 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:116,289,823...116,475,908 		JBrowse link
G Mst1 macrophage stimulating 1 involved_in ISO (PMID:19720831) RGD PMID:19720831 NCBI chr 8:108,767,886...108,773,425
Ensembl chr 8:108,768,839...108,773,416 		JBrowse link
G Mtcl2 microtubule crosslinking factor 2 involved_in ISO
IEA 		(PMID:20813965)
GO_REF:0000107 		RGD
Ensembl		 PMID:20813965 GO_REF:0000107 NCBI chr 3:145,669,102...145,741,578
Ensembl chr 3:145,675,443...145,740,871 		JBrowse link
G Mup4l1 major urinary protein 4 like 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 5:75,221,340...75,224,797
Ensembl chr 5:75,142,157...75,564,845 		JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 involved_in ISO (PMID:19651776) RGD PMID:19651776 NCBI chr  X:54,707,658...54,711,786
Ensembl chr  X:50,756,886...50,761,011 		JBrowse link
G Obp2a odorant binding protein 2A acts_upstream_of_or_within ISO MGI:2137691 (PMID:21135134) RGD PMID:21135134 NCBI chr 3:8,505,963...8,509,269
Ensembl chr 3:8,505,990...8,509,269 		JBrowse link
G Pgp phosphoglycolate phosphatase involved_in IMP
IEA
ISO 		PMID:26755581
GO_REF:0000107
(PMID:26755581) 		Ensembl
RGD		 PMID:26755581 PMID:26755581 GO_REF:0000107, RGD:10679995 NCBI chr10:13,495,232...13,497,858
Ensembl chr10:13,494,291...13,497,858 		JBrowse link
G Serpina12 serpin family A member 12 acts_upstream_of_or_within ISO
IEA 		(PMID:22837305)
GO_REF:0000107 		RGD
Ensembl		 PMID:22837305 GO_REF:0000107 NCBI chr 6:122,952,552...122,967,271
Ensembl chr 6:122,952,552...122,967,271 		JBrowse link
G Sik1 salt-inducible kinase 1 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:16148943)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:16148943 GO_REF:0000024 GO_REF:0000107 NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991 		JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (PMID:23142079), (PMID:25009184) RGD PMID:23142079 PMID:25009184 NCBI chr 7:8,733,056...8,738,543
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 IMP RGD PMID:21901280 RGD:152995490 NCBI chr 1:264,791,335...264,984,225
Ensembl chr 1:254,786,091...254,978,967 		JBrowse link
G Usp7 ubiquitin specific peptidase 7 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:28655758) 		UniProt
Ensembl
RGD		 PMID:28655758 GO_REF:0000024 GO_REF:0000107 NCBI chr10:6,880,684...6,925,355
Ensembl chr10:6,828,795...6,925,355 		JBrowse link
positive regulation of gluconeogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arpp19 cAMP-regulated phosphoprotein 19 involved_in ISO (PMID:9653196) RGD PMID:9653196 NCBI chr 8:75,779,640...75,802,474
Ensembl chr 8:75,779,523...75,802,452
Ensembl chr 8:75,779,523...75,802,452 		JBrowse link
G Cry1 cryptochrome circadian regulator 1 involved_in ISO (PMID:29937374) RGD PMID:29937374 NCBI chr 7:20,417,526...20,481,791
Ensembl chr 7:18,529,823...18,594,091 		JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 IMP RGD PMID:29656108 RGD:150520032 NCBI chr 5:116,295,691...116,323,219
Ensembl chr 5:111,178,703...111,244,794 		JBrowse link
G Ddb1 damage-specific DNA binding protein 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:28790135) 		UniProt
RGD		 PMID:28790135 GO_REF:0000024 NCBI chr 1:207,252,890...207,278,685
Ensembl chr 1:207,252,890...207,278,676 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 IMP RGD PMID:17526931 RGD:10400884 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428 		JBrowse link
G Foxo1 forkhead box O1 involved_in
acts_upstream_of_or_within 		ISS
ISO
IEA 		GO_REF:0000024
(PMID:17024043), (PMID:25009184)
(PMID:12783775)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:12783775 PMID:17024043 PMID:25009184 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Gcg glucagon acts_upstream_of_or_within ISO
IEA 		(PMID:24051374)
GO_REF:0000107 		RGD
Ensembl		 PMID:24051374 GO_REF:0000107 NCBI chr 3:67,522,489...67,531,533
Ensembl chr 3:47,113,914...47,122,929 		JBrowse link
G Gpt glutamic--pyruvic transaminase IDA RGD PMID:25865565 RGD:11342811 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IMP RGD PMID:24177414 RGD:10445837 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha involved_in IMP
IDA 		PMID:19651776 RGD
BHF-UCL		 PMID:16893891 PMID:24177414 PMID:19651776 RGD:1624992, RGD:10445837, RGD:8553501 NCBI chr 3:172,606,220...172,667,758
Ensembl chr 3:152,186,787...152,248,320 		JBrowse link
G Kat2a lysine acetyltransferase 2A acts_upstream_of_or_within ISO
IEA 		MGI:95674 (PMID:24051374)
GO_REF:0000107 		RGD
Ensembl		 PMID:24051374 GO_REF:0000107 NCBI chr10:86,132,535...86,140,877
Ensembl chr10:85,632,216...85,640,166 		JBrowse link
G Kat2b lysine acetyltransferase 2B acts_upstream_of_or_within ISO
IEA 		MGI:2155884|MGI:95674 (PMID:24051374)
GO_REF:0000107 		RGD
Ensembl		 PMID:24051374 GO_REF:0000107 NCBI chr 9:6,799,101...6,903,616
Ensembl chr 9:6,562,288...6,667,064 		JBrowse link
G Nnmt nicotinamide N-methyltransferase involved_in ISO (PMID:26168293) RGD PMID:26168293 NCBI chr 8:48,928,663...48,947,734
Ensembl chr 8:48,933,598...48,946,655 		JBrowse link
G Oprm1 opioid receptor, mu 1 IMP RGD PMID:34270714 RGD:401831046 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha acts_upstream_of_or_within ISO
IEA 		MGI:1857774 (PMID:15232616)
GO_REF:0000107 		RGD
Ensembl		 PMID:15232616 GO_REF:0000107 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha involved_in ISO (PMID:19651776) RGD PMID:19651776 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Ppp4r3a protein phosphatase 4, regulatory subunit 3A acts_upstream_of_or_within ISO
IEA 		(PMID:20876121)
GO_REF:0000107 		RGD
Ensembl		 PMID:20876121 GO_REF:0000107 NCBI chr 6:120,302,508...120,365,907
Ensembl chr 6:120,302,511...120,365,891 		JBrowse link
G Ppp4r3b protein phosphatase 4, regulatory subunit 3B acts_upstream_of_or_within ISO
IEA 		(PMID:20876121)
GO_REF:0000107 		RGD
Ensembl		 PMID:20876121 GO_REF:0000107 NCBI chr14:102,917,043...102,965,210
Ensembl chr14:102,917,443...103,068,192 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in NAS PMID:11903059 UniProt PMID:11903059 RGD:8554594 NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:54,240,137...54,275,978 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in IEA
ISO 		GO_REF:0000107
(PMID:23292513) 		Ensembl
RGD		 PMID:23292513 GO_REF:0000107 NCBI chr19:41,059,843...41,083,189
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Prkag1 protein kinase AMP-activated non-catalytic subunit gamma 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:131,842,058...131,859,484
Ensembl chr 7:129,963,105...129,980,561 		JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:10,744,695...10,985,939
Ensembl chr 4:10,010,890...10,252,142 		JBrowse link
G Prkag3 protein kinase AMP-activated non-catalytic subunit gamma 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:83,744,385...83,753,629
Ensembl chr 9:76,295,715...76,304,959 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:20484139) 		UniProt
Ensembl
RGD		 PMID:20484139 GO_REF:0000024 GO_REF:0000107 NCBI chr18:63,498,890...63,564,571
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
G Sirt1 sirtuin 1 involved_in IMP
ISO
IEA 		(PMID:15692560), (PMID:23142079), (PMID:30193097)
GO_REF:0000107
(PMID:26168293) 		RGD
Ensembl		 PMID:15692560 PMID:23142079 PMID:26168293 PMID:30193097 PMID:21212096 GO_REF:0000107, RGD:9585757 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sirt7 sirtuin 7 involved_in ISS
ISO 		GO_REF:0000024
(PMID:28655758) 		UniProt
RGD		 PMID:28655758 GO_REF:0000024 NCBI chr10:105,896,476...105,903,301
Ensembl chr10:105,896,476...105,903,172 		JBrowse link
G Stk11 serine/threonine kinase 11 IMP RGD PMID:17083919 RGD:2291956 NCBI chr 7:10,225,204...10,241,965
Ensembl chr 7:9,575,269...9,591,315 		JBrowse link
G Supt20h SPT20 homolog, SAGA complex component acts_upstream_of_or_within ISO MGI:95674 (PMID:24051374) RGD PMID:24051374 NCBI chr 2:138,897,316...138,930,493
Ensembl chr 2:138,897,416...138,930,495 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 acts_upstream_of_or_within ISO MGI:5430317 (PMID:23260145) RGD PMID:23260145 NCBI chr 1:264,791,335...264,984,225
Ensembl chr 1:254,786,091...254,978,967 		JBrowse link
G Wdr5 WD repeat domain 5 acts_upstream_of_or_within ISO MGI:1343094|MGI:95674 (PMID:24051374) RGD PMID:24051374 NCBI chr 3:10,836,964...10,856,682
Ensembl chr 3:10,837,025...10,856,671 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    regulation of biological process 13398
      regulation of cellular process 13032
        regulation of metabolic process 6776
          regulation of biosynthetic process 5581
            regulation of carbohydrate biosynthetic process 128
              regulation of gluconeogenesis 64
                negative regulation of gluconeogenesis 23
                positive regulation of gluconeogenesis 30
Path 2
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        primary metabolic process 10727
          carbohydrate metabolic process 650
            carbohydrate biosynthetic process 218
              monosaccharide biosynthetic process 109
                hexose biosynthetic process 103
                  gluconeogenesis 100
                    regulation of gluconeogenesis 64
                      negative regulation of gluconeogenesis 23
                      positive regulation of gluconeogenesis 30
paths to the root