Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:malate metabolic process
go back to main search page
Accession:GO:0006108 term browser browse the term
Definition:The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.
Synonyms:exact_synonym: malate metabolism


show annotations for term's descendants           Sort by:
malate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G D2hgdh D-2-hydroxyglutarate dehydrogenase involved_in ISO
IDA
IEA
ISS		 (PMID:33431826)
PMID:15070399
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:33431826 PMID:15070399 GO_REF:0000024 GO_REF:0000107, RGD:8553974 NCBI chr 9:94,350,555...94,368,384
Ensembl chr 9:94,350,576...94,368,382 		JBrowse link
G Fh fumarate hydratase involved_in ISO
IEA
IBA		 (PMID:30761759)
GO_REF:0000107
GO_REF:0000033
(PMID:21498518)		 RGD
Ensembl
GO_Central		 PMID:21498518 PMID:30761759 GO_REF:0000033 GO_REF:0000107 NCBI chr13:90,056,565...90,082,450
Ensembl chr13:87,524,337...87,550,266 		JBrowse link
G Lipf lipase F, gastric type acts_upstream_of_or_within IDA PMID:15809022 MGI PMID:15809022 RGD:1582471 NCBI chr 1:231,493,498...231,511,845
Ensembl chr 1:231,493,498...231,511,845 		JBrowse link
G Mdh1 malate dehydrogenase 1 involved_in IDA
IBA
IEA		 GO_REF:0000033
GO_REF:0000002		 GO_Central
InterPro
RGD		 PMID:17447164 PMID:12351438 GO_REF:0000002 GO_REF:0000033, RGD:1624966, RGD:2303499 NCBI chr14:99,831,934...99,847,227
Ensembl chr14:95,630,306...95,645,925 		JBrowse link
G Mdh1b malate dehydrogenase 1B involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000002		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 9:72,614,185...72,661,820
Ensembl chr 9:65,119,029...65,167,933 		JBrowse link
G Mdh2 malate dehydrogenase 2 involved_in IDA
IEA
ISO		 GO_REF:0000107
GO_REF:0000002
(PMID:16740313), (PMID:6576816)		 Ensembl
InterPro
RGD		 PMID:6576816 PMID:16740313 PMID:1898089 PMID:12351438 GO_REF:0000002 GO_REF:0000107, RGD:1582472, RGD:2303499 NCBI chr12:26,530,886...26,543,841
Ensembl chr12:20,894,262...20,907,271 		JBrowse link
G Me1 malic enzyme 1 involved_in ISS
IBA
IEA
ISO		 PMID:7622060
GO_REF:0000033
GO_REF:0000107
PMID:8187880
(PMID:7622060), (PMID:8187880)		 GO_Central
Ensembl
RGD		 PMID:7622060 PMID:8187880 PMID:7622060 PMID:8187880 GO_REF:0000033 GO_REF:0000107, RGD:8553596, RGD:8554832 NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:87,549,043...87,660,304 		JBrowse link
G Me2 malic enzyme 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:69,626,073...69,676,218
Ensembl chr18:67,355,795...67,400,987 		JBrowse link
G Me3 malic enzyme 3 involved_in ISO
IBA
IEA		 (PMID:7818469)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:7818469 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:152,946,595...153,148,026
Ensembl chr 1:143,534,139...143,733,132 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      metabolic process 12180
        small molecule metabolic process 1928
          organic acid metabolic process 1048
            oxoacid metabolic process 1026
              carboxylic acid metabolic process 1011
                dicarboxylic acid metabolic process 106
                  malate metabolic process 9
paths to the root