ONTOLOGY REPORT - ANNOTATIONS
Term: DNA-dependent protein kinase-DNA ligase 4 complex
Accession: GO:0005958
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Definition: A large protein complex which is involved in the repair of DNA double-strand breaks and, in mammals, V(D)J recombination events. It consists of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs), the DNA end-binding heterodimer Ku, the nuclear phosphoprotein XRCC4 or a homolog thereof, and DNA ligase IV.
Synonyms: alt_id: GO:0005959
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Lig4
DNA ligase 4
part_of
ISO IBA
(PMID:15194694), (PMID:34352203) GO_REF:0000033
RGD GO_Central
PMID:15194694 PMID:34352203
GO_REF:0000033
NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040
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Nhej1
nonhomologous end-joining factor 1
part_of
IEA ISS ISO
GO_REF:0000107 GO_REF:0000024 (PMID:34352203)
Ensembl UniProt RGD
PMID:34352203
GO_REF:0000024 GO_REF:0000107
NCBI chr 9:76,526,322...76,622,488
Ensembl chr 9:76,526,324...76,622,444
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Prkdc
protein kinase, DNA-activated, catalytic subunit
part_of
ISO
(PMID:15194694), (PMID:34352203)
RGD
PMID:15194694 PMID:34352203
NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
G
Xrcc4
X-ray repair cross complementing 4
part_of
ISO IBA
(PMID:15194694), (PMID:34352203) GO_REF:0000033
RGD GO_Central
PMID:15194694 PMID:34352203
GO_REF:0000033
NCBI chr 2:20,948,464...21,197,705
Ensembl chr 2:20,951,200...21,197,808
G
Xrcc5
X-ray repair cross complementing 5
part_of
TAS ISO
(PMID:34352203)
RGD
PMID:34352203 PMID:11966321
RGD:727219
NCBI chr 9:73,955,216...74,044,020
Ensembl chr 9:73,955,216...74,044,018
G
Xrcc6
X-ray repair cross complementing 6
part_of
ISO
(PMID:34352203)
RGD
PMID:34352203
NCBI chr 7:113,542,992...113,563,762
Ensembl chr 7:113,543,057...113,563,762
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