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ONTOLOGY REPORT - ANNOTATIONS


Term:DNA-dependent protein kinase-DNA ligase 4 complex
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Accession:GO:0005958 term browser browse the term
Definition:A large protein complex which is involved in the repair of DNA double-strand breaks and, in mammals, V(D)J recombination events. It consists of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs), the DNA end-binding heterodimer Ku, the nuclear phosphoprotein XRCC4 or a homolog thereof, and DNA ligase IV.
Synonyms:alt_id: GO:0005959



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DNA-dependent protein kinase-DNA ligase 4 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lig4 DNA ligase 4 part_of ISO
IBA
(PMID:15194694), (PMID:34352203)
GO_REF:0000033
RGD
GO_Central
PMID:15194694 PMID:34352203 GO_REF:0000033 NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040
JBrowse link
G Nhej1 nonhomologous end-joining factor 1 part_of IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:34352203)
Ensembl
UniProt
RGD
PMID:34352203 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:76,526,322...76,622,488
Ensembl chr 9:76,526,324...76,622,444
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit part_of ISO (PMID:15194694), (PMID:34352203) RGD PMID:15194694 PMID:34352203 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 part_of ISO
IBA
(PMID:15194694), (PMID:34352203)
GO_REF:0000033
RGD
GO_Central
PMID:15194694 PMID:34352203 GO_REF:0000033 NCBI chr 2:20,948,464...21,197,705
Ensembl chr 2:20,951,200...21,197,808
JBrowse link
G Xrcc5 X-ray repair cross complementing 5 part_of TAS
ISO
(PMID:34352203) RGD PMID:34352203 PMID:11966321 RGD:727219 NCBI chr 9:73,955,216...74,044,020
Ensembl chr 9:73,955,216...74,044,018
JBrowse link
G Xrcc6 X-ray repair cross complementing 6 part_of ISO (PMID:34352203) RGD PMID:34352203 NCBI chr 7:113,542,992...113,563,762
Ensembl chr 7:113,543,057...113,563,762
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20824
    protein-containing complex 6552
      nuclear protein-containing complex 1279
        DNA-dependent protein kinase-DNA ligase 4 complex 6
Path 2
Term Annotations click to browse term
  cellular_component 20824
    cellular anatomical structure 20625
      organelle 13967
        membrane-bounded organelle 12555
          intracellular membrane-bounded organelle 12003
            nucleus 7451
              nuclear protein-containing complex 1279
                DNA-dependent protein kinase-DNA ligase 4 complex 6
paths to the root