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ONTOLOGY REPORT - ANNOTATIONS

Term:clathrin-coated pit
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Accession:GO:0005905 term browser browse the term
Definition:A part of the endomembrane system in the form of an invagination of a membrane upon which a clathrin coat forms, and that can be converted by vesicle budding into a clathrin-coated vesicle. Coated pits form on the plasma membrane, where they are involved in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane, in the trans-Golgi network, and on some endosomes.
Synonyms:exact_synonym: coated pit
 xref: NIF_Subcellular:sao1969557946

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clathrin-coated pit term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aak1 AP2 associated kinase 1 located_in IEA UniProt GO_REF:0000043 GO_REF:0000044 NCBI chrNW_004624762:3,722,429...3,873,105
Ensembl chrNW_004624762:3,723,113...3,866,417 		JBrowse link
G Ackr3 atypical chemokine receptor 3 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624847:2,189,167...2,200,355
Ensembl chrNW_004624847:2,189,257...2,200,352 		JBrowse link
G Adcy8 adenylate cyclase 8 located_in ISO PMID:19158400 UniProt PMID:19158400 RGD:13800545 NCBI chrNW_004624735:24,891,803...25,149,817
Ensembl chrNW_004624735:24,891,583...25,149,900 		JBrowse link
G Ap1s1 adaptor related protein complex 1 subunit sigma 1 located_in IEA UniProt GO_REF:0000043 GO_REF:0000044 NCBI chrNW_004624740:16,111,004...16,117,075
Ensembl chrNW_004624740:16,111,004...16,116,992 		JBrowse link
G Ap1s2 adaptor related protein complex 1 subunit sigma 2 located_in IEA UniProt GO_REF:0000043 GO_REF:0000044 NCBI chrNW_004624829:608,065...637,096
Ensembl chrNW_004624829:608,065...634,479 		JBrowse link
G Ap1s3 adaptor related protein complex 1 subunit sigma 3 located_in IEA UniProt GO_REF:0000043 GO_REF:0000044 NCBI chrNW_004624823:1,438,830...1,498,903
Ensembl chrNW_004624823:1,438,864...1,500,116 		JBrowse link
G Ap2a1 adaptor related protein complex 2 subunit alpha 1 located_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624832:4,513,977...4,540,080
Ensembl chrNW_004624832:4,513,977...4,540,277 		JBrowse link
G Ap2a2 adaptor related protein complex 2 subunit alpha 2 located_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624766:21,568,217...21,616,389
Ensembl chrNW_004624766:21,567,050...21,616,392 		JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 located_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624730:72,386,376...72,395,392 JBrowse link
G Ap2s1 adaptor related protein complex 2 subunit sigma 1 located_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624832:6,788,149...6,797,026
Ensembl chrNW_004624832:6,787,149...6,797,131 		JBrowse link
G App amyloid beta precursor protein located_in IEA UniProt GO_REF:0000043 GO_REF:0000044 NCBI chrNW_004624745:13,904,912...14,159,374
Ensembl chrNW_004624745:13,902,577...14,159,372 		JBrowse link
G Arrb1 arrestin beta 1 located_in IEA UniProt GO_REF:0000043 GO_REF:0000044 NCBI chrNW_004624817:1,750,448...1,828,399
Ensembl chrNW_004624817:1,750,156...1,823,309 		JBrowse link
G Atat1 alpha tubulin acetyltransferase 1 located_in IEA UniProt GO_REF:0000043 GO_REF:0000044 NCBI chrNW_004624754:25,058,312...25,069,052
Ensembl chrNW_004624754:25,058,204...25,069,561 		JBrowse link
G Bcl2l1 BCL2 like 1 located_in ISO PMID:23792689 CAFA PMID:23792689 RGD:12793033 NCBI chrNW_004624741:788,445...838,513
Ensembl chrNW_004624741:789,355...839,507 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 is_active_in ISO (PMID:16923969) MGI PMID:16923969 NCBI chrNW_004624765:13,849,689...13,950,839
Ensembl chrNW_004624765:13,857,062...13,947,683 		JBrowse link
G Ccdc32 coiled-coil domain containing 32 located_in
part_of		 IEA
ISO		 (PMID:33859415) Ensembl
UniProt		 PMID:33859415 GO_REF:0000107 NCBI chrNW_004624804:7,851,669...7,867,037
Ensembl chrNW_004624804:7,850,945...7,867,045 		JBrowse link
G Cdhr5 cadherin related family member 5 ISO RGD PMID:10801787 RGD:633361 NCBI chrNW_004624766:21,843,506...21,849,827
Ensembl chrNW_004624766:21,843,518...21,850,506 		JBrowse link
G Clta clathrin light chain A located_in ISO
IEA		 RGD
UniProt		 PMID:14985443 GO_REF:0000043 RGD:2301373 NCBI chrNW_004624868:4,419,554...4,443,475
Ensembl chrNW_004624868:4,419,554...4,443,477 		JBrowse link
G Cltb clathrin light chain B located_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624733:13,707,594...13,738,814
Ensembl chrNW_004624733:13,707,155...13,738,814 		JBrowse link
G Cltc clathrin heavy chain located_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624871:1,439,975...1,507,514
Ensembl chrNW_004624871:1,439,838...1,510,911 		JBrowse link
G Cttn cortactin located_in ISO PMID:19995918 UniProt PMID:19995918 RGD:10047197 NCBI chrNW_004624767:16,842,341...16,884,449
Ensembl chrNW_004624767:16,847,459...16,880,183 		JBrowse link
G Cubn cubilin located_in ISO PMID:14576052
(PMID:15616221)		 UniProt
MGI		 PMID:14576052 PMID:15616221 RGD:8554807 NCBI chrNW_004624796:10,728,853...10,987,292
Ensembl chrNW_004624796:10,728,983...10,988,361 		JBrowse link
G Dab2 DAB adaptor protein 2 located_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624759:15,459,436...15,520,225
Ensembl chrNW_004624759:15,459,288...15,520,924 		JBrowse link
G Dgkd diacylglycerol kinase delta located_in ISO (PMID:17880279) UniProt PMID:17880279 NCBI chrNW_004624843:5,879,335...5,959,525
Ensembl chrNW_004624843:5,899,538...5,957,422 		JBrowse link
G Dnm1 dynamin 1 located_in ISO (PMID:8101525) UniProt PMID:8101525 NCBI chrNW_004624760:6,605,902...6,646,575
Ensembl chrNW_004624760:6,604,787...6,646,622 		JBrowse link
G Dnm1l dynamin 1 like located_in IEA UniProt GO_REF:0000043 GO_REF:0000044 NCBI chrNW_004624778:3,391,690...3,475,548 JBrowse link
G Dnm2 dynamin 2 located_in ISO PMID:19995918
(PMID:26437238)		 UniProt
MGI
RGD		 PMID:9725914 PMID:19995918 PMID:26437238 RGD:10047197 RGD:9685132 NCBI chrNW_004624828:2,727,136...2,805,248
Ensembl chrNW_004624828:2,727,112...2,807,319 		JBrowse link
G Epn3 epsin 3 located_in ISO (PMID:21115825) MGI PMID:21115825 NCBI chrNW_004624795:6,418,568...6,427,624
Ensembl chrNW_004624795:6,418,770...6,428,013 		JBrowse link
G Eps15 epidermal growth factor receptor pathway substrate 15 located_in ISO (PMID:20427320) MGI PMID:20427320 NCBI chrNW_004624859:1,584,024...1,754,395 JBrowse link
G Fcho1 FCH and mu domain containing endocytic adaptor 1 is_active_in
located_in		 ISO
IEA		 (PMID:20448150) ParkinsonsUK-UCL
TreeGrafter
UniProt		 PMID:20448150 GO_REF:0000043 GO_REF:0000044 GO_REF:0000118 NCBI chrNW_004624908:1,327,569...1,340,741
Ensembl chrNW_004624908:1,327,602...1,340,240 		JBrowse link
G Fcho2 FCH and mu domain containing endocytic adaptor 2 located_in
is_active_in		 IEA
ISO		 (PMID:20448150) UniProt
TreeGrafter
ParkinsonsUK-UCL		 PMID:20448150 GO_REF:0000043 GO_REF:0000044 GO_REF:0000118 NCBI chrNW_004624905:2,027,709...2,139,312
Ensembl chrNW_004624905:2,029,808...2,140,721 		JBrowse link
G Fchsd2 FCH and double SH3 domains 2 located_in ISO (PMID:29887380) UniProt PMID:29887380 NCBI chrNW_004624817:3,819,124...4,134,757
Ensembl chrNW_004624817:3,819,178...4,135,044 		JBrowse link
G Gas7 growth arrest specific 7 located_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624786:12,341,987...12,575,651
Ensembl chrNW_004624786:12,345,003...12,575,417 		JBrowse link
G Hip1r huntingtin interacting protein 1 related located_in ISO (PMID:10613908), (PMID:11564758) MGI PMID:10613908 PMID:11564758 NCBI chrNW_004624747:22,876,183...22,897,557
Ensembl chrNW_004624747:22,876,276...22,896,584 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 located_in ISO (PMID:11807771) BHF-UCL PMID:11807771 NCBI chrNW_004624889:2,736,727...2,746,333 JBrowse link
G Inpp5f inositol polyphosphate-5-phosphatase F located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624737:27,001,090...27,123,022
Ensembl chrNW_004624737:27,000,076...27,122,815 		JBrowse link
G Itsn1 intersectin 1 located_in ISO (PMID:26437238)
(PMID:20946875), (PMID:29887380)		 RGD
MGI
UniProt		 PMID:19258322 PMID:20946875 PMID:26437238 PMID:29887380 RGD:13461864 NCBI chrNW_004624745:21,847,593...22,055,141
Ensembl chrNW_004624745:21,906,187...22,050,822 		JBrowse link
G Ldlr low density lipoprotein receptor located_in ISO (PMID:15166224), (PMID:6091915) BHF-UCL PMID:6091915 PMID:15166224 NCBI chrNW_004624828:2,999,122...3,021,893
Ensembl chrNW_004624828:2,999,169...3,021,987 		JBrowse link
G LOC101697909 AP-1 complex subunit sigma-2 located_in IEA UniProt GO_REF:0000043 GO_REF:0000044 NCBI chrNW_004624978:410,502...411,235 JBrowse link
G LOC101708690 clathrin heavy chain 2 located_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624945:18,348...154,408
Ensembl chrNW_004624945:223...154,254 		JBrowse link
G LOC101712251 dynamin-1-like protein located_in IEA UniProt GO_REF:0000043 GO_REF:0000044 NCBI chrNW_004624758:365,219...368,500 JBrowse link
G LOC101717662 AP-1 complex subunit sigma-2 located_in IEA UniProt GO_REF:0000043 GO_REF:0000044 NCBI chrNW_004624765:24,493,581...24,494,042 JBrowse link
G LOC101719398 serotransferrin located_in ISO (PMID:12857860)
(PMID:20427320)		 UniProt
MGI		 PMID:12857860 PMID:20427320 NCBI chrNW_004624730:10,078,165...10,109,349 JBrowse link
G LOC101721754 AP-1 complex subunit sigma-2 located_in IEA UniProt GO_REF:0000043 GO_REF:0000044 NCBI chrNW_004624733:28,665,626...28,666,210 JBrowse link
G Lrp10 LDL receptor related protein 10 located_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624820:9,645,954...9,652,296
Ensembl chrNW_004624820:9,645,954...9,652,289 		JBrowse link
G Lrp2 LDL receptor related protein 2 located_in ISO (PMID:15616221) MGI PMID:15616221 NCBI chrNW_004624787:6,797,462...6,998,859
Ensembl chrNW_004624787:6,798,938...6,998,697 		JBrowse link
G Lrp3 LDL receptor related protein 3 located_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624794:9,892,300...9,904,320
Ensembl chrNW_004624794:9,892,690...9,904,261 		JBrowse link
G Myo6 myosin VI NOT|located_in ISO (PMID:12857860) UniProt PMID:12857860 NCBI chrNW_004624819:2,835,783...2,999,819
Ensembl chrNW_004624819:2,896,374...2,999,819 		JBrowse link
G Necap1 NECAP endocytosis associated 1 located_in ISO (PMID:14555962) UniProt PMID:14555962 NCBI chrNW_004624860:5,224,170...5,237,235
Ensembl chrNW_004624860:5,223,610...5,237,451 		JBrowse link
G Numb NUMB endocytic adaptor protein located_in ISO (PMID:26437238) MGI PMID:26437238 NCBI chrNW_004624734:27,994,662...28,144,719 JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein located_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624845:3,875,601...3,990,347
Ensembl chrNW_004624845:3,891,061...3,990,342 		JBrowse link
G Rab35 RAB35, member RAS oncogene family located_in ISO (PMID:16950109) UniProt PMID:16950109 NCBI chrNW_004624747:13,520,228...13,538,664
Ensembl chrNW_004624747:13,520,254...13,537,651 		JBrowse link
G Reps1 RALBP1 associated Eps domain containing 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624753:14,970,693...15,057,033
Ensembl chrNW_004624753:14,970,706...15,057,037 		JBrowse link
G Sele selectin E located_in ISO (PMID:18029551) BHF-UCL PMID:18029551 NCBI chrNW_004624826:7,624,852...7,635,330
Ensembl chrNW_004624826:7,626,380...7,635,309 		JBrowse link
G Sgip1 SH3GL interacting endocytic adaptor 1 located_in IEA UniProt
TreeGrafter		 GO_REF:0000043 GO_REF:0000044 GO_REF:0000118 NCBI chrNW_004624742:28,245,140...28,439,705
Ensembl chrNW_004624742:28,247,127...28,439,482 		JBrowse link
G Sh3bp4 SH3 domain binding protein 4 located_in IEA UniProt GO_REF:0000043 GO_REF:0000044 NCBI chrNW_004624847:1,007,940...1,078,882
Ensembl chrNW_004624847:1,044,831...1,078,984 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 ISO RGD PMID:1881917 RGD:2306204 NCBI chrNW_004624786:9,903,176...9,908,953
Ensembl chrNW_004624786:9,902,509...9,909,684 		JBrowse link
G Snap91 synaptosome associated protein 91 located_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624799:10,913,834...11,060,185
Ensembl chrNW_004624799:10,915,477...11,060,312 		JBrowse link
G Snx9 sorting nexin 9 located_in ISO (PMID:15703209) UniProt PMID:15703209 NCBI chrNW_004624785:283,886...374,740
Ensembl chrNW_004624785:282,512...374,378 		JBrowse link
G Sort1 sortilin 1 located_in ISO (PMID:11331584) BHF-UCL PMID:11331584 NCBI chrNW_004624772:5,044,948...5,123,300
Ensembl chrNW_004624772:5,049,045...5,123,365 		JBrowse link
G Sphk1 sphingosine kinase 1 located_in ISO (PMID:24929359) UniProt PMID:24929359 NCBI chrNW_004624801:6,253,219...6,257,128 JBrowse link
G Ston1 stonin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624738:29,747,179...29,803,676
Ensembl chrNW_004624738:29,785,501...29,803,752 		JBrowse link
G Tfap2a transcription factor AP-2 alpha located_in ISO (PMID:26437238) MGI PMID:26437238 NCBI chrNW_004624756:15,413,950...15,436,037
Ensembl chrNW_004624756:15,418,260...15,436,379 		JBrowse link
G Tfrc transferrin receptor located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624730:61,282,650...61,313,487
Ensembl chrNW_004624730:61,285,334...61,313,550 		JBrowse link
G Tnk2 tyrosine kinase non receptor 2 located_in ISO (PMID:21169560) UniProt PMID:21169560 NCBI chrNW_004624730:61,237,653...61,272,499
Ensembl chrNW_004624730:61,236,983...61,273,166 		JBrowse link
AP-2 adaptor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap2a1 adaptor related protein complex 2 subunit alpha 1 part_of IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000117 NCBI chrNW_004624832:4,513,977...4,540,080
Ensembl chrNW_004624832:4,513,977...4,540,277 		JBrowse link
G Ap2a2 adaptor related protein complex 2 subunit alpha 2 part_of IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000117 NCBI chrNW_004624766:21,568,217...21,616,389
Ensembl chrNW_004624766:21,567,050...21,616,392 		JBrowse link
G Ap2b1 adaptor related protein complex 2 subunit beta 1 part_of ISO (PMID:12086608)
(PMID:23676497)		 CAFA
UniProt		 PMID:12086608 PMID:23676497 NCBI chrNW_004624875:3,085,518...3,206,930
Ensembl chrNW_004624875:3,090,656...3,208,593 		JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 part_of ISO PMID:12086608
(PMID:23676497)		 CAFA
UniProt		 PMID:12086608 PMID:23676497 RGD:12793054 NCBI chrNW_004624730:72,386,376...72,395,392 JBrowse link
G Ap2s1 adaptor related protein complex 2 subunit sigma 1 part_of ISO
IEA		 RGD
InterPro		 PMID:7593184 GO_REF:0000002 RGD:2306270 NCBI chrNW_004624832:6,788,149...6,797,026
Ensembl chrNW_004624832:6,787,149...6,797,131 		JBrowse link
G Eps15 epidermal growth factor receptor pathway substrate 15 part_of ISO (PMID:17626015) UniProt PMID:17626015 NCBI chrNW_004624859:1,584,024...1,754,395 JBrowse link
G Sgip1 SH3GL interacting endocytic adaptor 1 part_of ISO (PMID:17626015) UniProt PMID:17626015 NCBI chrNW_004624742:28,245,140...28,439,705
Ensembl chrNW_004624742:28,247,127...28,439,482 		JBrowse link
G Slc18a3 solute carrier family 18 member A3 part_of ISO
IEA		 RGD
TreeGrafter		 PMID:14724281 GO_REF:0000118 RGD:2317430 NCBI chrNW_004624928:403,114...405,560
Ensembl chrNW_004624928:403,503...405,095 		JBrowse link
G Tbc1d5 TBC1 domain family member 5 located_in ISO (PMID:24603492) UniProt PMID:24603492 NCBI chrNW_004624821:2,398,211...3,068,212
Ensembl chrNW_004624821:2,398,042...2,806,263 		JBrowse link
clathrin coat of coated pit term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clta clathrin light chain A part_of IEA InterPro GO_REF:0000002 NCBI chrNW_004624868:4,419,554...4,443,475
Ensembl chrNW_004624868:4,419,554...4,443,477 		JBrowse link
G Cltb clathrin light chain B part_of IEA InterPro GO_REF:0000002 NCBI chrNW_004624733:13,707,594...13,738,814
Ensembl chrNW_004624733:13,707,155...13,738,814 		JBrowse link
G Cltc clathrin heavy chain part_of IEA InterPro GO_REF:0000002 NCBI chrNW_004624871:1,439,975...1,507,514
Ensembl chrNW_004624871:1,439,838...1,510,911 		JBrowse link
G Dab2 DAB adaptor protein 2 part_of ISO (PMID:11247302) UniProt PMID:11247302 NCBI chrNW_004624759:15,459,436...15,520,225
Ensembl chrNW_004624759:15,459,288...15,520,924 		JBrowse link
G Eps15 epidermal growth factor receptor pathway substrate 15 part_of IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624859:1,584,024...1,754,395 JBrowse link
G Eps15l1 epidermal growth factor receptor pathway substrate 15 like 1 part_of IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624908:965,948...1,014,235
Ensembl chrNW_004624908:966,087...1,014,130 		JBrowse link
G LOC101708690 clathrin heavy chain 2 part_of IEA InterPro GO_REF:0000002 NCBI chrNW_004624945:18,348...154,408
Ensembl chrNW_004624945:223...154,254 		JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein part_of ISO (PMID:10436022), (PMID:16262731) BHF-UCL PMID:10436022 PMID:16262731 NCBI chrNW_004624845:3,875,601...3,990,347
Ensembl chrNW_004624845:3,891,061...3,990,342 		JBrowse link
G Synj1 synaptojanin 1 part_of ISO PMID:9428629 ParkinsonsUK-UCL PMID:9428629 RGD:11059574 NCBI chrNW_004624745:20,881,312...20,984,242
Ensembl chrNW_004624745:20,881,317...20,984,184 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 18619
    cellular anatomical structure 18486
      membrane 8881
        clathrin-coated pit 70
          clathrin coat of coated pit + 17
paths to the root