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ONTOLOGY REPORT - ANNOTATIONS

Term:clathrin-coated pit
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Accession:GO:0005905 term browser browse the term
Definition:A part of the endomembrane system in the form of an invagination of a membrane upon which a clathrin coat forms, and that can be converted by vesicle budding into a clathrin-coated vesicle. Coated pits form on the plasma membrane, where they are involved in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane, in the trans-Golgi network, and on some endosomes.
Synonyms:exact_synonym: coated pit
 xref: NIF_Subcellular:sao1969557946


show annotations for term's descendants           Sort by:
clathrin-coated pit term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AAK1 AP2 associated kinase 1 located_in IEA UniProt GO_REF:0000043 GO_REF:0000044 NCBI chr2A:69,506,651...69,686,765
Ensembl chr2A:70,638,470...70,804,579 		JBrowse link
G ACKR3 atypical chemokine receptor 3 located_in IEA Ensembl GO_REF:0000107 NCBI chr2B:123,795,664...123,810,067
Ensembl chr2B:242,666,173...242,667,261 		JBrowse link
G ADCY8 adenylate cyclase 8 located_in ISO PMID:19158400 UniProt PMID:19158400 RGD:13800545 NCBI chr 8:127,418,407...127,681,217
Ensembl chr 8:130,398,288...130,661,073 		JBrowse link
G AP1S1 adaptor related protein complex 1 subunit sigma 1 located_in IEA UniProt GO_REF:0000043 GO_REF:0000044 NCBI chr 7:93,294,826...93,301,202
Ensembl chr 7:106,536,452...106,543,316 		JBrowse link
G AP1S2 adaptor related protein complex 1 subunit sigma 2 located_in IEA UniProt GO_REF:0000043 GO_REF:0000044 NCBI chr  X:8,449,885...8,478,932
Ensembl chr  X:15,807,476...15,836,172 		JBrowse link
G AP1S3 adaptor related protein complex 1 subunit sigma 3 located_in IEA UniProt GO_REF:0000043 GO_REF:0000044 NCBI chr2B:111,000,537...111,083,518
Ensembl chr2B:229,575,750...229,659,332 		JBrowse link
G AP2A1 adaptor related protein complex 2 subunit alpha 1 located_in IEA UniProt GO_REF:0000043 NCBI chr19:46,779,196...46,820,055
Ensembl chr19:55,694,070...55,736,570 		JBrowse link
G AP2A2 adaptor related protein complex 2 subunit alpha 2 located_in IEA UniProt GO_REF:0000043 NCBI chr11:945,170...1,034,860
Ensembl chr11:1,005,473...1,076,652 		JBrowse link
G AP2M1 adaptor related protein complex 2 subunit mu 1 located_in IEA Ensembl
UniProt		 GO_REF:0000043 GO_REF:0000107 NCBI chr 3:181,210,045...181,219,327
Ensembl chr 3:189,692,898...189,702,261 		JBrowse link
G APP amyloid beta precursor protein located_in IEA UniProt GO_REF:0000043 GO_REF:0000044 NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072 		JBrowse link
G ARRB1 arrestin beta 1 located_in IEA UniProt GO_REF:0000043 GO_REF:0000044 NCBI chr11:70,319,935...70,411,276
Ensembl chr11:73,630,276...73,654,155 		JBrowse link
G ATAT1 alpha tubulin acetyltransferase 1 located_in IEA UniProt GO_REF:0000043 GO_REF:0000044 NCBI chr 6:30,368,847...30,391,595
Ensembl chr 6:31,238,778...31,261,611 		JBrowse link
G BCL2L1 BCL2 like 1 located_in ISO PMID:23792689 CAFA PMID:23792689 RGD:12793033 NCBI chr20:27,955,688...28,015,950
Ensembl chr20:29,088,055...29,146,585 		JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 located_in
is_active_in		 IEA
ISO		 (PMID:16923969) Ensembl
MGI		 PMID:16923969 GO_REF:0000107 NCBI chr2B:89,631,622...89,823,438
Ensembl chr2B:207,780,741...207,961,072 		JBrowse link
G CCDC32 coiled-coil domain containing 32 part_of ISO (PMID:33859415) UniProt PMID:33859415 NCBI chr15:19,466,344...19,510,553
Ensembl chr15:37,726,474...37,763,602 		JBrowse link
G CDHR5 cadherin related family member 5 ISO RGD PMID:10801787 RGD:633361 Ensembl chr11:652,671...659,959 JBrowse link
G CLTA clathrin light chain A located_in ISO
IEA		 RGD
UniProt		 PMID:14985443 GO_REF:0000043 RGD:2301373 NCBI chr 9:36,040,566...36,061,744
Ensembl chr 9:36,840,868...36,862,528 		JBrowse link
G CLTB clathrin light chain B located_in IEA UniProt GO_REF:0000043 NCBI chr 5:171,689,273...171,713,198 JBrowse link
G CLTC clathrin heavy chain located_in IEA UniProt GO_REF:0000043 NCBI chr17:53,685,865...53,761,008
Ensembl chr17:58,529,750...58,603,636 		JBrowse link
G CLTCL1 clathrin heavy chain like 1 located_in IEA Ensembl
UniProt		 GO_REF:0000043 GO_REF:0000107 NCBI chr22:1,934,948...2,050,159
Ensembl chr22:17,613,828...17,726,231 		JBrowse link
G CTTN cortactin located_in ISO PMID:19995918 UniProt PMID:19995918 RGD:10047197 NCBI chr11:65,500,074...65,539,158
Ensembl chr11:68,794,162...68,823,857 		JBrowse link
G CUBN cubilin located_in IEA Ensembl GO_REF:0000107 NCBI chr10:17,141,464...17,446,867
Ensembl chr10:17,415,551...17,719,129 		JBrowse link
G DAB2 DAB adaptor protein 2 located_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:70,951,198...71,004,836
Ensembl chr 5:76,022,143...76,041,443 		JBrowse link
G DGKD diacylglycerol kinase delta located_in IEA Ensembl GO_REF:0000107 NCBI chr2B:120,582,278...120,701,165
Ensembl chr2B:239,525,401...239,611,873 		JBrowse link
G DNM1 dynamin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 9:99,324,385...99,376,262
Ensembl chr 9:128,004,508...128,044,690 		JBrowse link
G DNM1L dynamin 1 like located_in IEA UniProt GO_REF:0000043 GO_REF:0000044 NCBI chr12:53,476,553...53,541,421
Ensembl chr12:56,077,504...56,142,376 		JBrowse link
G DNM2 dynamin 2 located_in ISO (PMID:26437238)
PMID:19995918		 RGD
MGI
UniProt		 PMID:9725914 PMID:19995918 PMID:26437238 RGD:10047197 RGD:9685132 NCBI chr19:10,272,172...10,386,032
Ensembl chr19:10,933,672...11,106,478 		JBrowse link
G EPN3 epsin 3 located_in IEA Ensembl GO_REF:0000107 NCBI chr17:44,626,114...44,636,646
Ensembl chr17:49,504,119...49,509,729 		JBrowse link
G EPS15 epidermal growth factor receptor pathway substrate 15 located_in ISO (PMID:20427320) MGI PMID:20427320 NCBI chr 1:50,598,692...50,763,585
Ensembl chr 1:52,097,387...52,223,533 		JBrowse link
G FCHO1 FCH and mu domain containing endocytic adaptor 1 is_active_in
located_in		 ISO
IEA		 (PMID:20448150) ParkinsonsUK-UCL
TreeGrafter
UniProt
Ensembl		 PMID:20448150 GO_REF:0000043 GO_REF:0000044 GO_REF:0000107 GO_REF:0000118 NCBI chr19:17,230,202...17,271,133
Ensembl chr19:18,213,869...18,245,725 		JBrowse link
G FCHO2 FCH and mu domain containing endocytic adaptor 2 located_in
is_active_in		 IEA
ISO		 (PMID:20448150) UniProt
TreeGrafter
ParkinsonsUK-UCL
Ensembl		 PMID:20448150 GO_REF:0000043 GO_REF:0000044 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:42,223,201...42,361,317
Ensembl chr 5:42,824,621...42,958,565 		JBrowse link
G FCHSD2 FCH and double SH3 domains 2 located_in ISO (PMID:29887380) UniProt PMID:29887380 NCBI chr11:67,915,796...68,219,482 JBrowse link
G GAS7 growth arrest specific 7 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:41,454,100...41,743,777
Ensembl chr17:46,200,364...46,480,618 		JBrowse link
G HIP1R huntingtin interacting protein 1 related located_in IEA Ensembl GO_REF:0000107 NCBI chr12:120,438,841...120,467,489
Ensembl chr12:124,685,091...124,700,726 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr2B:84,729,615...84,743,352
Ensembl chr2B:202,623,497...202,636,959 		JBrowse link
G INPP5F inositol polyphosphate-5-phosphatase F located_in IEA Ensembl GO_REF:0000107 NCBI chr10:116,295,802...116,396,764
Ensembl chr10:119,712,696...119,813,444 		JBrowse link
G ITSN1 intersectin 1 located_in ISO
IEA		 RGD
Ensembl		 PMID:19258322 GO_REF:0000107 RGD:13461864 NCBI chr21:20,009,385...20,266,835
Ensembl chr21:33,457,081...33,625,248 		JBrowse link
G LDLR low density lipoprotein receptor located_in IEA Ensembl GO_REF:0000107 NCBI chr19:10,640,225...10,683,728
Ensembl chr19:11,357,311...11,396,791 		JBrowse link
G LRP10 LDL receptor related protein 10 located_in IEA UniProt GO_REF:0000043 NCBI chr14:3,688,934...3,698,778
Ensembl chr14:21,788,345...21,795,936 		JBrowse link
G LRP2 LDL receptor related protein 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr2B:56,407,871...56,640,471
Ensembl chr2B:173,873,767...174,103,697 		JBrowse link
G LRP3 LDL receptor related protein 3 located_in IEA UniProt GO_REF:0000043 NCBI chr19:30,116,649...30,129,964
Ensembl chr19:38,863,504...38,876,299 		JBrowse link
G MYO6 myosin VI NOT|located_in ISO (PMID:12857860) UniProt PMID:12857860 NCBI chr 6:73,593,794...73,764,352
Ensembl chr 6:76,951,634...77,048,796 		JBrowse link
G NECAP1 NECAP endocytosis associated 1 located_in ISO (PMID:14555962) UniProt PMID:14555962 NCBI chr12:8,201,908...8,217,043
Ensembl chr12:8,243,785...8,282,647 		JBrowse link
G NUMB NUMB endocytic adaptor protein located_in IEA Ensembl GO_REF:0000107 NCBI chr14:53,854,280...54,046,410
Ensembl chr14:72,714,555...72,798,037 		JBrowse link
G PICALM phosphatidylinositol binding clathrin assembly protein located_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:81,011,324...81,122,352
Ensembl chr11:84,619,241...84,730,684 		JBrowse link
G RAB35 RAB35, member RAS oncogene family located_in ISO (PMID:16950109) UniProt PMID:16950109 NCBI chr12:117,670,693...117,692,322 JBrowse link
G REPS1 RALBP1 associated Eps domain containing 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:136,662,837...136,748,743
Ensembl chr 6:140,748,309...140,830,499 		JBrowse link
G SELE selectin E located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:145,205,684...145,217,143
Ensembl chr 1:148,930,437...148,938,313 		JBrowse link
G SGIP1 SH3GL interacting endocytic adaptor 1 located_in IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000043 GO_REF:0000044 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:65,782,856...65,999,721
Ensembl chr 1:67,669,222...67,877,073 		JBrowse link
G SH3BP4 SH3 domain binding protein 4 located_in IEA UniProt GO_REF:0000043 GO_REF:0000044 NCBI chr2B:122,179,431...122,284,430
Ensembl chr2B:241,089,624...241,149,524 		JBrowse link
G SLC2A4 solute carrier family 2 member 4 ISO RGD PMID:1881917 RGD:2306204 NCBI chr17:7,312,605...7,319,430
Ensembl chr17:7,299,966...7,306,344 		JBrowse link
G SNAP91 synaptosome associated protein 91 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:81,441,792...81,600,505
Ensembl chr 6:84,720,850...84,874,407 		JBrowse link
G SNX9 sorting nexin 9 located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:155,724,026...155,844,553
Ensembl chr 6:157,824,918...157,903,357 		JBrowse link
G SORT1 sortilin 1 located_in ISO (PMID:11331584) BHF-UCL PMID:11331584 NCBI chr 1:111,687,119...111,775,339 JBrowse link
G SPHK1 sphingosine kinase 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr17:70,331,370...70,336,043
Ensembl chr17:75,883,329...75,886,481 		JBrowse link
G STON1 stonin 1 located_in ISO (PMID:26437238) MGI PMID:26437238 NCBI chr2A:48,656,425...48,722,288
Ensembl chr2A:49,577,562...49,721,845 		JBrowse link
G TF transferrin located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:130,799,063...130,830,227
Ensembl chr 3:138,274,159...138,305,476 		JBrowse link
G TFAP2A transcription factor AP-2 alpha located_in ISO (PMID:26437238) MGI PMID:26437238 NCBI chr 6:10,237,834...10,260,843 JBrowse link
G TFRC transferrin receptor located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:193,384,817...193,417,532
Ensembl chr 3:203,333,953...203,373,998 		JBrowse link
G TNK2 tyrosine kinase non receptor 2 located_in ISO (PMID:21169560) UniProt PMID:21169560 NCBI chr 3:193,254,017...193,302,863 JBrowse link
AP-2 adaptor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP2A1 adaptor related protein complex 2 subunit alpha 1 part_of IEA InterPro
UniProt
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 NCBI chr19:46,779,196...46,820,055
Ensembl chr19:55,694,070...55,736,570 		JBrowse link
G AP2A2 adaptor related protein complex 2 subunit alpha 2 part_of IEA InterPro
UniProt
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 NCBI chr11:945,170...1,034,860
Ensembl chr11:1,005,473...1,076,652 		JBrowse link
G AP2B1 adaptor related protein complex 2 subunit beta 1 part_of IEA Ensembl GO_REF:0000107 NCBI chr17:21,070,132...21,208,610
Ensembl chr17:21,363,121...21,501,721 		JBrowse link
G AP2M1 adaptor related protein complex 2 subunit mu 1 part_of IEA Ensembl GO_REF:0000107 NCBI chr 3:181,210,045...181,219,327
Ensembl chr 3:189,692,898...189,702,261 		JBrowse link
G AP2S1 adaptor related protein complex 2 subunit sigma 1 part_of ISO (PMID:12086608)
PMID:2040623		 RGD
CAFA
MGI		 PMID:2040623 PMID:7593184 PMID:12086608 RGD:2306270 RGD:727584 NCBI chr19:43,827,907...43,840,682 JBrowse link
G BTBD8 BTB domain containing 8 located_in ISO PMID:29262337 UniProt PMID:29262337 RGD:13601995 NCBI chr 1:94,739,780...94,843,172
Ensembl chr 1:93,569,680...93,587,229 		JBrowse link
G EPS15 epidermal growth factor receptor pathway substrate 15 part_of ISO (PMID:17626015) UniProt PMID:17626015 NCBI chr 1:50,598,692...50,763,585
Ensembl chr 1:52,097,387...52,223,533 		JBrowse link
G SGIP1 SH3GL interacting endocytic adaptor 1 part_of IEA Ensembl GO_REF:0000107 NCBI chr 1:65,782,856...65,999,721
Ensembl chr 1:67,669,222...67,877,073 		JBrowse link
G SLC18A3 solute carrier family 18 member A3 part_of ISO
IEA		 RGD
TreeGrafter		 PMID:14724281 GO_REF:0000118 RGD:2317430 NCBI chr10:44,630,006...44,632,419 JBrowse link
G TBC1D5 TBC1 domain family member 5 part_of
located_in		 IEA
ISO		 (PMID:24603492) Ensembl
UniProt		 PMID:24603492 GO_REF:0000107 NCBI chr 3:17,080,589...17,664,776
Ensembl chr 3:17,416,307...17,768,132 		JBrowse link
clathrin coat of coated pit term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLTA clathrin light chain A part_of IEA InterPro GO_REF:0000002 NCBI chr 9:36,040,566...36,061,744
Ensembl chr 9:36,840,868...36,862,528 		JBrowse link
G CLTB clathrin light chain B part_of IEA InterPro GO_REF:0000002 NCBI chr 5:171,689,273...171,713,198 JBrowse link
G CLTC clathrin heavy chain part_of IEA InterPro GO_REF:0000002 NCBI chr17:53,685,865...53,761,008
Ensembl chr17:58,529,750...58,603,636 		JBrowse link
G CLTCL1 clathrin heavy chain like 1 part_of IEA InterPro GO_REF:0000002 NCBI chr22:1,934,948...2,050,159
Ensembl chr22:17,613,828...17,726,231 		JBrowse link
G DAB2 DAB adaptor protein 2 part_of ISO (PMID:11247302) UniProt PMID:11247302 NCBI chr 5:70,951,198...71,004,836
Ensembl chr 5:76,022,143...76,041,443 		JBrowse link
G EPS15 epidermal growth factor receptor pathway substrate 15 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr 1:50,598,692...50,763,585
Ensembl chr 1:52,097,387...52,223,533 		JBrowse link
G EPS15L1 epidermal growth factor receptor pathway substrate 15 like 1 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr19:15,842,964...15,959,492
Ensembl chr19:16,821,793...16,908,571 		JBrowse link
G PICALM phosphatidylinositol binding clathrin assembly protein part_of IEA Ensembl GO_REF:0000107 NCBI chr11:81,011,324...81,122,352
Ensembl chr11:84,619,241...84,730,684 		JBrowse link
G SYNJ1 synaptojanin 1 part_of ISO PMID:9428629 ParkinsonsUK-UCL PMID:9428629 RGD:11059574 NCBI chr21:18,990,526...19,088,839
Ensembl chr21:32,368,949...32,466,994 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20468
    cellular anatomical structure 20035
      membrane 8142
        clathrin-coated pit 67
          clathrin coat of coated pit + 18
paths to the root