ONTOLOGY REPORT - ANNOTATIONS
Term: clathrin-coated pit
Accession: GO:0005905
browse the term
Definition: A part of the endomembrane system in the form of an invagination of a membrane upon which a clathrin coat forms, and that can be converted by vesicle budding into a clathrin-coated vesicle. Coated pits form on the plasma membrane, where they are involved in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane, in the trans-Golgi network, and on some endosomes.
Synonyms: exact_synonym: coated pit
xref: NIF_Subcellular:sao1969557946
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Aak1
AP2 associated kinase 1
located_in
ISS
GO_REF:0000024
UniProt
GO_REF:0000024
NCBI chr 4:119,300,128...119,451,834
Ensembl chr 4:119,295,257...119,450,969
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Ackr3
atypical chemokine receptor 3
located_in
ISS ISO
GO_REF:0000024 (PMID:22457824)
UniProt RGD
PMID:22457824
GO_REF:0000024
NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237
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Adcy8
adenylate cyclase 8
located_in
IDA
PMID:19158400
UniProt
PMID:19158400
RGD:13800545
NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911
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Ap1s1
adaptor related protein complex 1 subunit sigma 1
located_in
IEA
GO_REF:0000044
UniProt
GO_REF:0000044
NCBI chr12:19,625,267...19,635,792
Ensembl chr12:19,625,332...19,756,713
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Ap1s2
adaptor related protein complex 1 subunit sigma 2
located_in
IEA
GO_REF:0000044
UniProt
GO_REF:0000044
NCBI chr X:30,572,746...30,598,961
Ensembl chr X:30,572,751...30,597,262
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Ap1s3
adaptor related protein complex 1 subunit sigma 3
located_in
IEA
GO_REF:0000044
UniProt
GO_REF:0000044
NCBI chr 9:80,950,402...81,009,889
Ensembl chr 9:80,950,715...81,009,798
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Ap2m1
adaptor related protein complex 2 subunit mu 1
located_in
ISO IEA
(PMID:31104773) GO_REF:0000043
RGD UniProt
PMID:31104773
GO_REF:0000043
NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140
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Ap2s1
adaptor related protein complex 2 subunit sigma 1
located_in
IEA
GO_REF:0000043
UniProt
GO_REF:0000043
NCBI chr 1:77,417,496...77,428,903
Ensembl chr 1:77,417,477...77,428,905
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App
amyloid beta precursor protein
located_in
IEA
GO_REF:0000044
UniProt
GO_REF:0000044
NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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Arrb1
arrestin, beta 1
located_in
IEA
GO_REF:0000044
UniProt
GO_REF:0000044
NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061
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Arrb2
arrestin, beta 2
located_in
IEA
GO_REF:0000044
UniProt
GO_REF:0000044
NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
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Atat1
alpha tubulin acetyltransferase 1
located_in
IEA
GO_REF:0000044 GO_REF:0000043
UniProt
GO_REF:0000043 GO_REF:0000044
NCBI chr20:2,844,595...2,857,809
Ensembl chr20:2,844,616...2,861,964
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Bcl2l1
Bcl2-like 1
located_in
IDA
PMID:23792689
CAFA
PMID:23792689
RGD:12793033
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 Ensembl chr 1:141,253,523...141,303,479
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Bmpr2
bone morphogenetic protein receptor type 2
is_active_in
ISO
(PMID:16923969)
RGD
PMID:16923969
NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809
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Ccdc32
coiled-coil domain containing 32
part_of
ISO ISS
(PMID:33859415) GO_REF:0000024
RGD UniProt
PMID:33859415
GO_REF:0000024
NCBI chr 3:105,998,429...106,010,985
Ensembl chr 3:105,998,430...106,010,975
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Cdhr5
cadherin-related family member 5
IDA
RGD
PMID:10801787
RGD:633361
NCBI chr 1:196,373,110...196,381,609
Ensembl chr 1:196,373,112...196,381,543
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Clta
clathrin, light chain A
IDA
RGD
PMID:14985443
RGD:2301373
NCBI chr 5:58,244,253...58,263,480
Ensembl chr 5:58,245,442...58,263,472
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Cltc
clathrin heavy chain
located_in
ISO
(PMID:26437238)
RGD
PMID:26437238
NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737
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Cttn
cortactin
located_in
IDA
PMID:19995918
UniProt
PMID:19995918
RGD:10047197
NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164
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Cubn
cubilin
located_in
IEA ISO IDA
GO_REF:0000107 (PMID:15616221) PMID:14576052
Ensembl RGD
PMID:15616221 PMID:14576052
GO_REF:0000107, RGD:8554807
NCBI chr17:76,385,046...76,593,133
Ensembl chr17:76,385,060...76,593,231
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Dab2
DAB adaptor protein 2
located_in is_active_in
IEA IBA ISO
GO_REF:0000107 GO_REF:0000033 (PMID:12857860)
Ensembl GO_Central RGD
PMID:12857860
GO_REF:0000033 GO_REF:0000107
NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
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Dgkd
diacylglycerol kinase, delta
located_in
ISO
(PMID:17880279)
RGD
PMID:17880279
NCBI chr 9:88,516,686...88,607,349
Ensembl chr 9:88,516,715...88,607,345
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Dnm1
dynamin 1
located_in
ISS IEA ISO
GO_REF:0000024 GO_REF:0000107 (PMID:8101525)
UniProt Ensembl RGD
PMID:8101525
GO_REF:0000024 GO_REF:0000107
NCBI chr 3:15,604,782...15,648,654
Ensembl chr 3:15,604,784...15,648,538
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Dnm1l
dynamin 1-like
located_in
IEA IDA
GO_REF:0000044 PMID:23792689
UniProt
PMID:23792689
GO_REF:0000044, RGD:12793033
NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
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Dnm2
dynamin 2
located_in
IDA ISO
(PMID:26437238) PMID:19995918
RGD
PMID:26437238 PMID:9725914 PMID:19995918
RGD:9685132 , RGD:10047197
NCBI chr 8:19,978,313...20,060,162
Ensembl chr 8:19,978,400...20,060,157
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ENSRNOG00000063241
located_in
IEA
GO_REF:0000044
UniProt
GO_REF:0000044
Ensembl chr13:26,511,609...26,513,494
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Epn1
Epsin 1
located_in
IEA
GO_REF:0000044
UniProt
GO_REF:0000044
NCBI chr 1:68,742,491...68,760,570
Ensembl chr 1:68,742,789...68,758,874
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Epn3
epsin 3
located_in
IEA ISO
GO_REF:0000107 (PMID:21115825)
Ensembl RGD
PMID:21115825
GO_REF:0000107
NCBI chr10:79,438,978...79,449,516
Ensembl chr10:79,438,978...79,447,356
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Eps15
epidermal growth factor receptor pathway substrate 15
located_in
ISO
(PMID:20427320)
RGD
PMID:20427320
NCBI chr 5:124,045,865...124,146,221
Ensembl chr 5:124,045,926...124,146,221
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Fcho1
FCH and mu domain containing endocytic adaptor 1
is_active_in located_in
ISO
(PMID:20448150) (PMID:22484487)
RGD
PMID:20448150 PMID:22484487
NCBI chr16:18,413,452...18,430,795
Ensembl chr16:18,413,363...18,435,104
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Fcho2
FCH and mu domain containing endocytic adaptor 2
located_in is_active_in
ISS ISO IBA IEA
GO_REF:0000024 (PMID:20448150) (PMID:21762413) GO_REF:0000033 GO_REF:0000044 (PMID:21762413), (PMID:22484487)
UniProt RGD GO_Central
PMID:20448150 PMID:21762413 PMID:22484487
GO_REF:0000024 GO_REF:0000033 GO_REF:0000044
NCBI chr 2:30,079,143...30,181,639
Ensembl chr 2:30,080,962...30,181,241
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Fchsd2
FCH and double SH3 domains 2
located_in
ISO
(PMID:29887380)
RGD
PMID:29887380
NCBI chr 1:155,444,471...155,685,350
Ensembl chr 1:155,444,460...155,685,539
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Fnbp1
formin binding protein 1
located_in
IEA
GO_REF:0000044
UniProt
GO_REF:0000044
NCBI chr 3:14,309,067...14,424,378
Ensembl chr 3:14,309,640...14,424,881
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Hip1r
huntingtin interacting protein 1 related
located_in
ISO
(PMID:10613908), (PMID:11564758)
RGD
PMID:10613908 PMID:11564758
NCBI chr12:32,590,164...32,618,841
Ensembl chr12:32,590,165...32,618,734
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Hspd1
heat shock protein family D (Hsp60) member 1
located_in
ISO
(PMID:11807771)
RGD
PMID:11807771
NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
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Inpp5f
inositol polyphosphate-5-phosphatase F
located_in
ISO
(PMID:25869669)
RGD
PMID:25869669
NCBI chr 1:183,190,480...183,270,276
Ensembl chr 1:183,190,480...183,270,276
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Itsn1
intersectin 1
located_in
IDA ISO IEA
(PMID:26437238) (PMID:20946875), (PMID:29887380) GO_REF:0000107
RGD Ensembl
PMID:20946875 PMID:26437238 PMID:29887380 PMID:19258322
GO_REF:0000107, RGD:13461864
NCBI chr11:30,978,590...31,160,645
Ensembl chr11:30,978,590...31,160,645
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Ldlr
low density lipoprotein receptor
located_in
ISO IEA
(PMID:15166224), (PMID:6091915) GO_REF:0000044
RGD UniProt
PMID:6091915 PMID:15166224
GO_REF:0000044
NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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Lrp1
LDL receptor related protein 1
located_in
IEA
GO_REF:0000043
UniProt
GO_REF:0000043
NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
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Lrp10
LDL receptor related protein 10
located_in
IEA
GO_REF:0000043
UniProt
GO_REF:0000043
NCBI chr15:27,921,335...27,927,507
Ensembl chr15:27,920,259...27,927,505
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Lrp12
LDL receptor related protein 12
located_in
IEA
GO_REF:0000043
UniProt
GO_REF:0000043
NCBI chr 7:70,941,068...71,012,409
Ensembl chr 7:70,941,068...71,012,441
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Lrp2
LDL receptor related protein 2
located_in
IEA ISO
GO_REF:0000107 (PMID:15616221)
Ensembl RGD
PMID:15616221
GO_REF:0000107
NCBI chr 3:54,189,305...54,346,769
Ensembl chr 3:54,189,308...54,346,708
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Lrp3
LDL receptor related protein 3
located_in
IEA
GO_REF:0000043
UniProt
GO_REF:0000043
NCBI chr 1:87,843,815...87,859,147
Ensembl chr 1:87,844,868...87,859,110
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Lrp8
LDL receptor related protein 8
located_in
IEA
GO_REF:0000044
UniProt
GO_REF:0000044
NCBI chr 5:122,563,468...122,635,434
Ensembl chr 5:122,563,453...122,631,352
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Myo6
myosin VI
NOT|located_in
ISO IEA
(PMID:12857860) GO_REF:0000044
RGD UniProt
PMID:12857860
GO_REF:0000044
NCBI chr 8:81,087,157...81,242,022
Ensembl chr 8:81,087,139...81,239,292
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Necap1
NECAP endocytosis associated 1
located_in
IEA ISO
GO_REF:0000107 (PMID:14555962)
Ensembl RGD
PMID:14555962
GO_REF:0000107
NCBI chr 4:156,103,935...156,119,068
Ensembl chr 4:156,103,988...156,119,068
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Necap2
NECAP endocytosis associated 2
located_in
ISS
GO_REF:0000024
UniProt
GO_REF:0000024
NCBI chr 5:153,370,338...153,382,753
Ensembl chr 5:153,370,338...153,382,729
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Numb
NUMB, endocytic adaptor protein
located_in
IEA ISO
GO_REF:0000107 (PMID:26437238)
Ensembl RGD
PMID:26437238
GO_REF:0000107
NCBI chr 6:103,431,400...103,553,422
Ensembl chr 6:103,431,400...103,553,354
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Ocrl
OCRL, inositol polyphosphate-5-phosphatase
located_in
IEA
GO_REF:0000044
UniProt
GO_REF:0000044
NCBI chr X:127,089,508...127,140,362
Ensembl chr X:127,089,590...127,140,362
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Picalm
phosphatidylinositol binding clathrin assembly protein
located_in is_active_in
ISO IBA ISS
(PMID:10436022), (PMID:25898166) (PMID:12832620) GO_REF:0000033 GO_REF:0000024
RGD GO_Central UniProt
PMID:10436022 PMID:12832620 PMID:25898166
GO_REF:0000024 GO_REF:0000033
NCBI chr 1:144,056,415...144,138,045
Ensembl chr 1:144,056,721...144,137,557
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Rab35
RAB35, member RAS oncogene family
located_in
ISO IEA
(PMID:16950109) GO_REF:0000107
RGD Ensembl
PMID:16950109
GO_REF:0000107
NCBI chr12:40,967,102...40,981,183
Ensembl chr12:40,967,103...40,991,195
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Reps1
RALBP1 associated Eps domain containing 1
located_in
ISO
(PMID:20946875)
RGD
PMID:20946875
NCBI chr 1:12,697,742...12,775,562
Ensembl chr 1:12,697,747...12,775,561
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Sele
selectin E
located_in
ISO
(PMID:18029551)
RGD
PMID:18029551
NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
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Sgip1
SH3GL interacting endocytic adaptor 1
located_in
ISO IEA
(PMID:20946875) GO_REF:0000044
RGD UniProt
PMID:20946875
GO_REF:0000044
NCBI chr 5:117,536,752...117,734,593
Ensembl chr 5:117,537,746...117,734,575
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Sh3bp4
SH3-domain binding protein 4
located_in
IEA
GO_REF:0000044
UniProt
GO_REF:0000044
NCBI chr 9:89,660,156...89,739,163
Ensembl chr 9:89,660,156...89,739,163
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Slc2a4
solute carrier family 2 member 4
IDA
RGD
PMID:1881917
RGD:2306204
NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
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Snap91
synaptosome associated protein 91
is_active_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 8:87,738,056...87,852,690
Ensembl chr 8:87,738,824...87,852,367
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Snx9
sorting nexin 9
located_in
ISO
(PMID:15703209)
RGD
PMID:15703209
NCBI chr 1:46,424,897...46,510,096
Ensembl chr 1:46,423,553...46,509,036
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Sort1
sortilin 1
located_in
ISO IEA
(PMID:11331584) GO_REF:0000107
RGD Ensembl
PMID:11331584
GO_REF:0000107
NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354
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Sphk1
sphingosine kinase 1
located_in
ISS IEA ISO
GO_REF:0000024 GO_REF:0000107 (PMID:24929359)
UniProt Ensembl RGD
PMID:24929359
GO_REF:0000024 GO_REF:0000107
NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240
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Ston1
stonin 1
located_in
ISO
(PMID:26437238)
RGD
PMID:26437238
NCBI chr 6:5,843,186...5,892,557
Ensembl chr 6:5,843,185...5,892,449
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Tf
transferrin
located_in
ISO
(PMID:12857860) (PMID:20427320)
RGD
PMID:12857860 PMID:20427320
NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
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Tfap2a
transcription factor AP-2 alpha
located_in
ISO
(PMID:26437238)
RGD
PMID:26437238
NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507
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Tfrc
transferrin receptor
located_in
ISO
(PMID:12857860) (PMID:18434600)
RGD
PMID:12857860 PMID:18434600
NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
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Tmprss6
transmembrane serine protease 6
located_in
IEA
GO_REF:0000043
UniProt
GO_REF:0000043
NCBI chr 7:109,991,008...110,021,626
Ensembl chr 7:109,985,931...110,021,624
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Tnk2
tyrosine kinase, non-receptor, 2
located_in
ISO
(PMID:21169560)
RGD
PMID:21169560
NCBI chr11:68,114,725...68,154,254
Ensembl chr11:68,114,726...68,154,009
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Vldlr
very low density lipoprotein receptor
located_in
IEA
GO_REF:0000044
UniProt
GO_REF:0000044
NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920
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Ap2a1
adaptor related protein complex 2 subunit alpha 1
part_of
ISO IBA
(PMID:23676497) GO_REF:0000033
RGD GO_Central
PMID:23676497
GO_REF:0000033
NCBI chr 1:95,384,306...95,414,170
Ensembl chr 1:95,384,309...95,414,147
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Ap2a2
adaptor related protein complex 2 subunit alpha 2
part_of
ISO IBA IEA IMP
(PMID:23676497) GO_REF:0000033 GO_REF:0000117 PMID:12086608
RGD GO_Central UniProt
PMID:23676497 PMID:12086608
GO_REF:0000033 GO_REF:0000117, RGD:12793054
NCBI chr 1:196,652,315...196,725,609
Ensembl chr 1:196,652,337...196,725,603
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Ap2b1
adaptor related protein complex 2 subunit beta 1
part_of
ISO
(PMID:12086608), (PMID:23676497) (PMID:23676497)
RGD
PMID:12086608 PMID:23676497
NCBI chr10:68,099,397...68,205,023
Ensembl chr10:68,099,547...68,205,013
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Ap2m1
adaptor related protein complex 2 subunit mu 1
part_of
IDA ISO IBA
PMID:12086608 (PMID:23676497) GO_REF:0000033
RGD GO_Central
PMID:23676497 PMID:12086608
GO_REF:0000033, RGD:12793054
NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140
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Ap2s1
adaptor related protein complex 2 subunit sigma 1
part_of
IDA ISO IEA
(PMID:12086608) GO_REF:0000107 GO_REF:0000002 PMID:2040623
RGD Ensembl InterPro
PMID:12086608 PMID:7593184 PMID:2040623
GO_REF:0000002 GO_REF:0000107, RGD:2306270 , RGD:727584
NCBI chr 1:77,417,496...77,428,903
Ensembl chr 1:77,417,477...77,428,905
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Btbd8
BTB domain containing 8
located_in
IDA
PMID:29262337
UniProt
PMID:29262337
RGD:13601995
NCBI chr14:2,265,187...2,338,426
Ensembl chr14:2,266,454...2,334,393
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Eps15
epidermal growth factor receptor pathway substrate 15
part_of
ISO
(PMID:17626015)
RGD
PMID:17626015
NCBI chr 5:124,045,865...124,146,221
Ensembl chr 5:124,045,926...124,146,221
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Sgip1
SH3GL interacting endocytic adaptor 1
part_of
ISS ISO IEA
PMID:17626015 (PMID:17626015) GO_REF:0000107
RGD Ensembl
PMID:17626015 PMID:17626015
GO_REF:0000107, RGD:8554282
NCBI chr 5:117,536,752...117,734,593
Ensembl chr 5:117,537,746...117,734,575
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Slc18a3
solute carrier family 18 member A3
part_of
IDA IBA
GO_REF:0000033
GO_Central RGD
PMID:14724281
GO_REF:0000033, RGD:2317430
NCBI chr16:7,713,630...7,716,491
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Ston1
stonin 1
part_of
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 6:5,843,186...5,892,557
Ensembl chr 6:5,843,185...5,892,449
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Ston2
stonin 2
part_of
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 6:110,567,485...110,676,376
Ensembl chr 6:110,567,485...110,676,376
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Tbc1d5
TBC1 domain family, member 5
located_in
ISO
(PMID:24603492)
RGD
PMID:24603492
NCBI chr 9:3,503,328...4,017,131
Ensembl chr 9:3,513,623...4,016,913
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Clta
clathrin, light chain A
part_of
NAS IEA
GO_REF:0000002
InterPro RGD
PMID:3563513
GO_REF:0000002, RGD:70686
NCBI chr 5:58,244,253...58,263,480
Ensembl chr 5:58,245,442...58,263,472
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Cltb
clathrin, light chain B
part_of
NAS
PMID:3563513
RGD UniProt
PMID:3563513 PMID:3563513
RGD:70686 , RGD:70686
NCBI chr17:10,001,512...10,019,201
Ensembl chr17:10,001,513...10,019,169
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Cltc
clathrin heavy chain
part_of
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737
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Dab2
DAB adaptor protein 2
part_of
ISO
(PMID:11247302)
RGD
PMID:11247302
NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
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Eps15
epidermal growth factor receptor pathway substrate 15
part_of
IBA ISO
GO_REF:0000033 (PMID:18434600)
GO_Central RGD
PMID:18434600
GO_REF:0000033
NCBI chr 5:124,045,865...124,146,221
Ensembl chr 5:124,045,926...124,146,221
G
Eps15l1
epidermal growth factor receptor pathway substrate 15-like 1
part_of
IBA ISO
GO_REF:0000033 (PMID:18434600)
GO_Central RGD
PMID:18434600
GO_REF:0000033
NCBI chr16:17,426,345...17,501,677
Ensembl chr16:17,426,421...17,501,677
G
Picalm
phosphatidylinositol binding clathrin assembly protein
part_of
ISO IEA
(PMID:10436022), (PMID:16262731) GO_REF:0000107
RGD Ensembl
PMID:10436022 PMID:16262731
GO_REF:0000107
NCBI chr 1:144,056,415...144,138,045
Ensembl chr 1:144,056,721...144,137,557
G
Synj1
synaptojanin 1
part_of
IDA
PMID:9428629
ParkinsonsUK-UCL
PMID:9428629
RGD:11059574
NCBI chr11:30,192,629...30,269,447
Ensembl chr11:30,192,629...30,269,220
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all