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ONTOLOGY REPORT - ANNOTATIONS

Term:neurofilament
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Accession:GO:0005883 term browser browse the term
Definition:A type of intermediate filament found in the core of neuronal axons. Neurofilaments are heteropolymers composed of three type IV polypeptides: NF-L, NF-M, and NF-H (for low, middle, and high molecular weight). Neurofilaments are responsible for the radial growth of an axon and determine axonal diameter.
Synonyms:exact_synonym: type IV intermediate filament
 xref: NIF_Subcellular:sao1316272517;   Wikipedia:Neurofilament
 only_in_taxon: NCBITaxon:6072 ! Eumetazoa


show annotations for term's descendants           Sort by:
neurofilament term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cldn11 claudin 11 located_in ISO
IEA		 (PMID:30734065)
GO_REF:0000107		 RGD
Ensembl		 PMID:30734065 GO_REF:0000107 NCBI chr 2:112,207,745...112,221,050
Ensembl chr 2:112,207,745...112,221,050 		JBrowse link
G Dlgap2 DLG associated protein 2 located_in NAS PMID:9286858 UniProt PMID:9286858 RGD:8554678 NCBI chr16:74,786,771...75,496,402
Ensembl chr16:74,791,509...75,496,407 		JBrowse link
G Dmd dystrophin IDA RGD PMID:11326752 RGD:12880030 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207 		JBrowse link
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A located_in ISO UniProtKB:P12036 (PMID:24327345) RGD PMID:24327345 NCBI chr11:33,890,706...34,009,420
Ensembl chr11:33,890,490...34,009,420 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A located_in IDA RGD PMID:19362128 RGD:401938622 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Ina internexin neuronal intermediate filament protein, alpha located_in IEA
ISO		 GO_REF:0000107
(PMID:10221457)		 Ensembl
RGD		 PMID:10221457 GO_REF:0000107 NCBI chr 1:245,896,775...245,908,330
Ensembl chr 1:245,896,775...245,908,330 		JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 located_in IEA
ISO		 GO_REF:0000107
(PMID:17727637)		 Ensembl
RGD		 PMID:17727637 GO_REF:0000107 NCBI chr 5:146,955,607...146,978,601
Ensembl chr 5:146,955,607...146,978,601 		JBrowse link
G Nefh neurofilament heavy chain located_in
is_active_in		 ISO
IBA		 (PMID:8634266)
GO_REF:0000033
(PMID:10221457), (PMID:15248193), (PMID:20176735)		 RGD
GO_Central		 PMID:8634266 PMID:10221457 PMID:15248193 PMID:20176735 GO_REF:0000033 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351 		JBrowse link
G Nefl neurofilament light chain located_in IDA
ISO		 (PMID:15857389)
(PMID:3920075), (PMID:8634266)
(PMID:10221457), (PMID:15242779), (PMID:8821035)		 RGD PMID:3920075 PMID:8634266 PMID:8821035 PMID:10221457 PMID:15242779 More... RGD:9743935 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793 		JBrowse link
G Nefm neurofilament medium chain located_in IDA
ISO		 (PMID:10221457), (PMID:10482234), (PMID:12971893), (PMID:15248193) RGD PMID:10221457 PMID:10482234 PMID:12971893 PMID:15248193 PMID:7721944 RGD:9743935 NCBI chr15:42,360,449...42,365,753
Ensembl chr15:42,360,454...42,365,755 		JBrowse link
G Nrp1 neuropilin 1 located_in ISO (PMID:15814794) RGD PMID:15814794 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633 		JBrowse link
G Pcp4 Purkinje cell protein 4 IDA RGD PMID:10556647 RGD:9850249 NCBI chr11:35,759,711...35,861,725
Ensembl chr11:35,800,713...35,861,725 		JBrowse link
G Prph peripherin located_in ISO (PMID:10221457) RGD PMID:10221457 NCBI chr 7:130,218,149...130,222,136
Ensembl chr 7:130,218,357...130,222,136 		JBrowse link
G Shank2 SH3 and multiple ankyrin repeat domains 2 located_in ISS
ISO		 GO_REF:0000024
(PMID:19299912)		 BHF-UCL
RGD		 PMID:19299912 GO_REF:0000024 NCBI chr 1:199,146,210...199,590,962
Ensembl chr 1:199,169,429...199,589,394 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20833
    cellular anatomical structure 20633
      cytoplasm 11893
        neurofilament 14
Path 2
Term Annotations click to browse term
  cellular_component 20833
    cellular anatomical structure 20633
      organelle 13975
        intracellular organelle 13569
          intracellular membraneless organelle 5268
            cytoskeleton 2384
              intermediate filament cytoskeleton 213
                intermediate filament 177
                  neurofilament 14
paths to the root