ONTOLOGY REPORT - ANNOTATIONS
Term: eukaryotic translation initiation factor 3 complex
Accession: GO:0005852
browse the term
Definition: A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs.
Synonyms: exact_synonym: eIF-3; eIF3
only_in_taxon: NCBITaxon:2759 ! Eukaryota
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Ddx3x
DEAD-box helicase 3, X-linked
located_in
ISO
(PMID:18628297)
RGD
PMID:18628297
NCBI chr X:9,479,532...9,493,169
Ensembl chr X:9,479,532...9,493,168
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Eif3a
eukaryotic translation initiation factor 3, subunit A
part_of
ISO IEA ISS
(PMID:17322308), (PMID:17581632), (PMID:18599441), (PMID:25849773) (PMID:17581632) GO_REF:0000104 GO_REF:0000024
RGD UniProt
PMID:17322308 PMID:17581632 PMID:18599441 PMID:25849773
GO_REF:0000024 GO_REF:0000104
NCBI chr 1:259,902,767...259,932,976
Ensembl chr 1:259,902,680...259,932,976
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Eif3b
eukaryotic translation initiation factor 3, subunit B
part_of
ISO IBA IEA ISS
(PMID:17322308), (PMID:17581632), (PMID:18599441), (PMID:25849773), (PMID:8995410) (PMID:17581632) GO_REF:0000033 GO_REF:0000104 GO_REF:0000024
RGD GO_Central UniProt
PMID:8995410 PMID:17322308 PMID:17581632 PMID:18599441 PMID:25849773
GO_REF:0000024 GO_REF:0000033 GO_REF:0000104
NCBI chr12:14,196,403...14,220,865
Ensembl chr12:14,196,403...14,220,886
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Eif3c
eukaryotic translation initiation factor 3, subunit C
part_of
ISO IBA IEA ISS
(PMID:17322308), (PMID:17581632), (PMID:18599441), (PMID:25849773) (PMID:17581632) GO_REF:0000033 GO_REF:0000104 GO_REF:0000024
RGD GO_Central UniProt
PMID:17322308 PMID:17581632 PMID:18599441 PMID:25849773
GO_REF:0000024 GO_REF:0000033 GO_REF:0000104
NCBI chr 1:181,134,604...181,152,489
Ensembl chr 1:181,134,604...181,152,493
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Eif3d
eukaryotic translation initiation factor 3, subunit D
part_of
ISO IBA IEA ISS
(PMID:17322308), (PMID:17581632), (PMID:18599441), (PMID:25849773), (PMID:27462815) (PMID:17581632) GO_REF:0000033 GO_REF:0000104 GO_REF:0000024
RGD GO_Central UniProt
PMID:17322308 PMID:17581632 PMID:18599441 PMID:25849773 PMID:27462815
GO_REF:0000024 GO_REF:0000033 GO_REF:0000104
NCBI chr 7:109,539,795...109,552,184
Ensembl chr 7:109,539,356...109,552,206
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Eif3e
eukaryotic translation initiation factor 3 subunit E
part_of
ISS ISO IBA
GO_REF:0000024 (PMID:17581632) GO_REF:0000033 (PMID:17322308), (PMID:17581632), (PMID:18599441), (PMID:25849773), (PMID:9295280)
UniProt RGD GO_Central
PMID:9295280 PMID:17322308 PMID:17581632 PMID:18599441 PMID:25849773
GO_REF:0000024 GO_REF:0000033
NCBI chr 7:74,339,848...74,372,483
Ensembl chr 7:74,339,828...74,373,096
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Eif3el1
eukaryotic translation initiation factor 3, subunit E like 1
part_of
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:73,774,491...73,775,984
Ensembl chr 1:73,774,487...73,776,003
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Eif3f
eukaryotic translation initiation factor 3, subunit F
part_of
ISO
(PMID:17322308), (PMID:17581632), (PMID:18599441), (PMID:25849773) (PMID:17581632)
RGD
PMID:17322308 PMID:17581632 PMID:18599441 PMID:25849773
NCBI chr 1:162,934,220...162,943,204
Ensembl chr 1:162,934,212...162,943,204
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Eif3g
eukaryotic translation initiation factor 3, subunit G
part_of
ISO IEA ISS
(PMID:17322308), (PMID:17581632), (PMID:18599441), (PMID:25849773) (PMID:17581632) GO_REF:0000104 GO_REF:0000024
RGD UniProt
PMID:17322308 PMID:17581632 PMID:18599441 PMID:25849773
GO_REF:0000024 GO_REF:0000104
NCBI chr 8:19,429,728...19,433,760
Ensembl chr 8:19,429,643...19,433,808
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Eif3h
eukaryotic translation initiation factor 3, subunit H
part_of
ISO IBA ISS IEA
(PMID:17322308), (PMID:17581632), (PMID:18599441), (PMID:25849773) (PMID:17581632) GO_REF:0000033 GO_REF:0000024 GO_REF:0000104
RGD GO_Central UniProt
PMID:17322308 PMID:17581632 PMID:18599441 PMID:25849773
GO_REF:0000024 GO_REF:0000033 GO_REF:0000104
NCBI chr 7:83,091,037...83,174,451
Ensembl chr 7:83,091,039...83,174,451
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Eif3i
eukaryotic translation initiation factor 3, subunit I
part_of
ISO IEA ISS
(PMID:17322308), (PMID:17581632), (PMID:18599441), (PMID:25849773) (PMID:17581632) GO_REF:0000104 GO_REF:0000024
RGD UniProt
PMID:17322308 PMID:17581632 PMID:18599441 PMID:25849773
GO_REF:0000024 GO_REF:0000104
NCBI chr 5:141,935,135...141,942,589
Ensembl chr 5:141,935,044...141,942,676
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Eif3j
eukaryotic translation initiation factor 3, subunit J
part_of
ISO IBA IEA ISS
(PMID:17322308), (PMID:18599441) GO_REF:0000033 GO_REF:0000104 GO_REF:0000024
RGD GO_Central UniProt
PMID:17322308 PMID:18599441
GO_REF:0000024 GO_REF:0000033 GO_REF:0000104
NCBI chr 3:108,985,103...109,007,341
Ensembl chr 3:108,985,118...109,007,953
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Eif3k
eukaryotic translation initiation factor 3, subunit K
part_of
ISO IBA
(PMID:17322308), (PMID:17581632), (PMID:18599441), (PMID:25849773) (PMID:17581632) GO_REF:0000033
RGD GO_Central
PMID:17322308 PMID:17581632 PMID:18599441 PMID:25849773
GO_REF:0000033
NCBI chr 1:84,260,127...84,270,051
Ensembl chr 1:84,259,673...84,270,302
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Eif3l
eukaryotic translation initiation factor 3, subunit L
part_of
ISO IBA
(PMID:17322308), (PMID:17581632), (PMID:18599441), (PMID:25849773) (PMID:17581632) GO_REF:0000033
RGD GO_Central
PMID:17322308 PMID:17581632 PMID:18599441 PMID:25849773
GO_REF:0000033
NCBI chr 7:110,652,565...110,663,614
Ensembl chr 7:110,627,107...110,663,614
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Eif3m
eukaryotic translation initiation factor 3, subunit M
part_of
ISO IBA
(PMID:17322308), (PMID:18599441), (PMID:25849773) GO_REF:0000033
RGD GO_Central
PMID:17322308 PMID:18599441 PMID:25849773
GO_REF:0000033
NCBI chr 3:91,424,754...91,442,358
Ensembl chr 3:91,416,325...91,442,392
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ENSRNOG00000065184
part_of
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
Ensembl chr16:42,493,031...42,494,134
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Eif3a
eukaryotic translation initiation factor 3, subunit A
part_of
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:259,902,767...259,932,976
Ensembl chr 1:259,902,680...259,932,976
G
Eif3e
eukaryotic translation initiation factor 3 subunit E
part_of
IEA
GO_REF:0000104
UniProt
GO_REF:0000104
NCBI chr 7:74,339,848...74,372,483
Ensembl chr 7:74,339,828...74,373,096
G
Eif3el1
eukaryotic translation initiation factor 3, subunit E like 1
part_of
IEA
GO_REF:0000104
UniProt
GO_REF:0000104
NCBI chr 1:73,774,491...73,775,984
Ensembl chr 1:73,774,487...73,776,003
G
Eif3a
eukaryotic translation initiation factor 3, subunit A
part_of
IBA ISO
GO_REF:0000033 (PMID:24003236)
GO_Central RGD
PMID:24003236
GO_REF:0000033
NCBI chr 1:259,902,767...259,932,976
Ensembl chr 1:259,902,680...259,932,976
G
Eif3b
eukaryotic translation initiation factor 3, subunit B
part_of
ISO
(PMID:24003236)
RGD
PMID:24003236
NCBI chr12:14,196,403...14,220,865
Ensembl chr12:14,196,403...14,220,886
G
Eif3c
eukaryotic translation initiation factor 3, subunit C
part_of
ISO
(PMID:24003236)
RGD
PMID:24003236
NCBI chr 1:181,134,604...181,152,489
Ensembl chr 1:181,134,604...181,152,493
G
Eif3d
eukaryotic translation initiation factor 3, subunit D
part_of
ISO
(PMID:24003236)
RGD
PMID:24003236
NCBI chr 7:109,539,795...109,552,184
Ensembl chr 7:109,539,356...109,552,206
G
Eif3f
eukaryotic translation initiation factor 3, subunit F
part_of
IBA ISO
GO_REF:0000033 (PMID:24003236)
GO_Central RGD
PMID:24003236
GO_REF:0000033
NCBI chr 1:162,934,220...162,943,204
Ensembl chr 1:162,934,212...162,943,204
G
Eif3h
eukaryotic translation initiation factor 3, subunit H
part_of
IEA ISO
GO_REF:0000107 (PMID:24003236)
Ensembl RGD
PMID:24003236
GO_REF:0000107
NCBI chr 7:83,091,037...83,174,451
Ensembl chr 7:83,091,039...83,174,451
G
Eif3i
eukaryotic translation initiation factor 3, subunit I
part_of
IEA IBA ISO
GO_REF:0000107 GO_REF:0000033 (PMID:24003236)
Ensembl GO_Central RGD
PMID:24003236
GO_REF:0000033 GO_REF:0000107
NCBI chr 5:141,935,135...141,942,589
Ensembl chr 5:141,935,044...141,942,676
G
Eif3m
eukaryotic translation initiation factor 3, subunit M
part_of
ISO
(PMID:24003236)
RGD
PMID:24003236
NCBI chr 3:91,424,754...91,442,358
Ensembl chr 3:91,416,325...91,442,392
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