ONTOLOGY REPORT - ANNOTATIONS
Term: smooth endoplasmic reticulum
Accession: GO:0005790
browse the term
Definition: The smooth endoplasmic reticulum (smooth ER or SER) has no ribosomes attached to it. The smooth ER is the recipient of the proteins synthesized in the rough ER. Those proteins to be exported are passed to the Golgi complex, the resident proteins are returned to the rough ER and the lysosomal proteins after phosphorylation of their mannose residues are passed to the lysosomes. Glycosylation of the glycoproteins also continues. The smooth ER is the site of synthesis of lipids, including the phospholipids. The membranes of the smooth ER also contain enzymes that catalyze a series of reactions to detoxify both lipid-soluble drugs and harmful products of metabolism. Large quantities of certain compounds such as phenobarbital cause an increase in the amount of the smooth ER.
Synonyms: exact_synonym: SER; smooth ER
xref: NIF_Subcellular:sao710427438; Wikipedia:Endoplasmic_reticulum#Smooth_endoplasmic_reticulum
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Aqp8
aquaporin 8
located_in
ISO
(PMID:14512882)
UniProt
PMID:14512882
NCBI chrNW_004955493:3,550,697...3,558,875
Ensembl chrNW_004955493:3,550,120...3,559,206
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Calr
calreticulin
located_in
ISO
PMID:22665516
UniProt
PMID:22665516
RGD:8553430
NCBI chrNW_004955415:31,985,147...31,989,372
Ensembl chrNW_004955415:31,985,147...31,989,372
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Canx
calnexin
located_in
ISO
PMID:22665516
UniProt
PMID:22665516
RGD:8553430
NCBI chrNW_004955408:850,773...894,362
Ensembl chrNW_004955408:848,808...894,362
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Dnajc3
DnaJ heat shock protein family (Hsp40) member C3
located_in
ISO
PMID:22665516
UniProt
PMID:22665516
RGD:8553430
NCBI chrNW_004955404:14,361,540...14,412,533
Ensembl chrNW_004955404:14,360,832...14,412,533
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Erp29
endoplasmic reticulum protein 29
located_in
ISO
PMID:22665516
UniProt
PMID:22665516
RGD:8553430
NCBI chrNW_004955482:8,572,227...8,579,589
Ensembl chrNW_004955482:8,572,227...8,579,946
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Gabarap
GABA type A receptor-associated protein
located_in
ISO
(PMID:11146101)
MGI
PMID:11146101
NCBI chrNW_004955467:9,667,938...9,670,067
Ensembl chrNW_004955467:9,667,941...9,670,067
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Hsp90b1
heat shock protein 90 beta family member 1
located_in
ISO
PMID:22665516
UniProt
PMID:22665516
RGD:8553430
NCBI chrNW_004955405:38,629,691...38,645,202
Ensembl chrNW_004955405:38,629,691...38,645,202
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Hspa5
heat shock protein family A (Hsp70) member 5
located_in
ISO
PMID:22665516
UniProt
PMID:22665516
RGD:8553430
NCBI chrNW_004955419:3,055,420...3,060,208
Ensembl chrNW_004955419:3,055,420...3,062,131
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Hyou1
hypoxia up-regulated 1
located_in
ISO
PMID:22665516
UniProt
PMID:22665516
RGD:8553430
NCBI chrNW_004955412:20,149,104...20,161,378
Ensembl chrNW_004955412:20,148,953...20,161,172
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Jph4
junctophilin 4
located_in
ISO
(PMID:17347645)
MGI
PMID:17347645
NCBI chrNW_004955409:36,785,003...36,795,196
Ensembl chrNW_004955409:36,785,003...36,795,196
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Kcnn2
potassium calcium-activated channel subfamily N member 2
located_in
ISO
(PMID:17347645)
MGI
PMID:17347645
NCBI chrNW_004955408:34,223,523...34,366,191
Ensembl chrNW_004955408:34,109,334...34,368,114
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Mapk8ip3
mitogen-activated protein kinase 8 interacting protein 3
located_in
ISO
(PMID:16606357)
MGI
PMID:16606357
NCBI chrNW_004955442:15,498,909...15,545,298
Ensembl chrNW_004955442:15,498,909...15,545,298
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Myo5a
myosin VA
is_active_in
ISO
(PMID:21151132)
SynGO
PMID:21151132
NCBI chrNW_004955409:2,409,503...2,530,539
Ensembl chrNW_004955409:2,428,815...2,530,012
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Pdia3
protein disulfide isomerase family A member 3
located_in
ISO
PMID:22665516
UniProt
PMID:22665516
RGD:8553430
NCBI chrNW_004955416:10,197,957...10,221,104
Ensembl chrNW_004955416:10,198,099...10,220,792
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Pdia4
protein disulfide isomerase family A member 4
located_in
ISO
PMID:22665516
UniProt
PMID:22665516
RGD:8553430
NCBI chrNW_004955491:4,344,874...4,360,205
Ensembl chrNW_004955491:4,344,874...4,360,205
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Pdia6
protein disulfide isomerase family A member 6
located_in
ISO
PMID:22665516
UniProt
PMID:22665516
RGD:8553430
NCBI chrNW_004955487:5,735,698...5,744,601
Ensembl chrNW_004955487:5,735,698...5,748,015
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Plcb4
phospholipase C beta 4
located_in is_active_in
ISO
(PMID:15579147)
MGI SynGO
PMID:15579147
NCBI chrNW_004955415:19,108,120...19,462,084
Ensembl chrNW_004955415:19,310,917...19,463,098
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Ppib
peptidylprolyl isomerase B
located_in
ISO
PMID:22665516
UniProt
PMID:22665516
RGD:8553430
NCBI chrNW_004955450:11,241,279...11,246,628
Ensembl chrNW_004955450:11,241,279...11,249,056
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Prdx4
peroxiredoxin 4
located_in
ISO
PMID:22665516
UniProt
PMID:22665516
RGD:8553430
NCBI chrNW_004955509:4,111,501...4,132,529
Ensembl chrNW_004955509:4,116,379...4,132,529
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Psen1
presenilin 1
located_in
ISO
(PMID:10508860), (PMID:9632714)
CAFA
PMID:9632714 PMID:10508860
NCBI chrNW_004955523:2,128,529...2,210,737
Ensembl chrNW_004955523:2,128,529...2,210,737
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Rpl10
ribosomal protein L10
located_in
ISO
(PMID:10508860)
CAFA
PMID:10508860
NCBI chrNW_004955580:903,618...906,439
Ensembl chrNW_004955580:903,412...906,439
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Rtn1
reticulon 1
located_in
ISO
PMID:23454728
MGI
PMID:23454728
RGD:8693349
NCBI chrNW_004955466:13,290,419...13,454,387
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Ryr1
ryanodine receptor 1
located_in
ISO
(PMID:23454728)
MGI
PMID:23454728
NCBI chrNW_004955468:879,807...1,000,118
Ensembl chrNW_004955468:879,951...1,000,036
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Ryr2
ryanodine receptor 2
located_in
ISO
(PMID:23454728)
MGI
PMID:23454728
NCBI chrNW_004955492:2,647,597...3,275,512
Ensembl chrNW_004955492:2,648,956...3,076,509
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Syvn1
synoviolin 1
located_in
ISO
(PMID:16186510)
ParkinsonsUK-UCL
PMID:16186510
NCBI chrNW_004955422:20,067,933...20,074,947
Ensembl chrNW_004955422:20,068,848...20,073,850
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Th
tyrosine hydroxylase
located_in
ISO
(PMID:12457228)
BHF-UCL
PMID:12457228
NCBI chrNW_004955422:13,943,590...13,951,102
Ensembl chrNW_004955422:13,943,552...13,951,137
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Aldob
aldolase, fructose-bisphosphate B
ISO
RGD
PMID:234468
RGD:2313431
NCBI chrNW_004955419:24,377,427...24,389,909
Ensembl chrNW_004955419:24,377,427...24,389,909
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Ftcd
formimidoyltransferase cyclodeaminase
located_in
ISO
(PMID:14697341)
BHF-UCL
PMID:14697341
NCBI chrNW_004955407:42,608,249...42,617,167
Ensembl chrNW_004955407:42,607,872...42,617,166
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Napepld
N-acyl phosphatidylethanolamine phospholipase D
is_active_in
ISO
(PMID:18234884)
SynGO
PMID:18234884
NCBI chrNW_004955410:8,217,684...8,233,302
Ensembl chrNW_004955410:8,220,400...8,247,486
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Stx17
syntaxin 17
located_in
ISO
PMID:10930465
UniProt
PMID:10930465
RGD:8553381
NCBI chrNW_004955419:25,674,771...25,741,357
Ensembl chrNW_004955419:25,674,771...25,741,355
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Ttyh1
tweety family member 1
located_in
ISO
(PMID:20568244)
MGI
PMID:20568244
NCBI chrNW_004955567:1,523,534...1,538,963
Ensembl chrNW_004955567:1,523,534...1,538,963
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