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ONTOLOGY REPORT - ANNOTATIONS


Term:smooth endoplasmic reticulum
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Accession:GO:0005790 term browser browse the term
Definition:The smooth endoplasmic reticulum (smooth ER or SER) has no ribosomes attached to it. The smooth ER is the recipient of the proteins synthesized in the rough ER. Those proteins to be exported are passed to the Golgi complex, the resident proteins are returned to the rough ER and the lysosomal proteins after phosphorylation of their mannose residues are passed to the lysosomes. Glycosylation of the glycoproteins also continues. The smooth ER is the site of synthesis of lipids, including the phospholipids. The membranes of the smooth ER also contain enzymes that catalyze a series of reactions to detoxify both lipid-soluble drugs and harmful products of metabolism. Large quantities of certain compounds such as phenobarbital cause an increase in the amount of the smooth ER.
Synonyms:exact_synonym: SER;   smooth ER
 xref: NIF_Subcellular:sao710427438;   Wikipedia:Endoplasmic_reticulum#Smooth_endoplasmic_reticulum


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smooth endoplasmic reticulum term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp8 aquaporin 8 located_in ISO (PMID:14512882) UniProt PMID:14512882 NCBI chrNW_004955493:3,550,697...3,558,875
Ensembl chrNW_004955493:3,550,120...3,559,206
JBrowse link
G Calr calreticulin located_in ISO PMID:22665516 UniProt PMID:22665516 RGD:8553430 NCBI chrNW_004955415:31,985,147...31,989,372
Ensembl chrNW_004955415:31,985,147...31,989,372
JBrowse link
G Canx calnexin located_in ISO PMID:22665516 UniProt PMID:22665516 RGD:8553430 NCBI chrNW_004955408:850,773...894,362
Ensembl chrNW_004955408:848,808...894,362
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 located_in ISO PMID:22665516 UniProt PMID:22665516 RGD:8553430 NCBI chrNW_004955404:14,361,540...14,412,533
Ensembl chrNW_004955404:14,360,832...14,412,533
JBrowse link
G Erp29 endoplasmic reticulum protein 29 located_in ISO PMID:22665516 UniProt PMID:22665516 RGD:8553430 NCBI chrNW_004955482:8,572,227...8,579,589
Ensembl chrNW_004955482:8,572,227...8,579,946
JBrowse link
G Gabarap GABA type A receptor-associated protein located_in ISO (PMID:11146101) MGI PMID:11146101 NCBI chrNW_004955467:9,667,938...9,670,067
Ensembl chrNW_004955467:9,667,941...9,670,067
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 located_in ISO PMID:22665516 UniProt PMID:22665516 RGD:8553430 NCBI chrNW_004955405:38,629,691...38,645,202
Ensembl chrNW_004955405:38,629,691...38,645,202
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 located_in ISO PMID:22665516 UniProt PMID:22665516 RGD:8553430 NCBI chrNW_004955419:3,055,420...3,060,208
Ensembl chrNW_004955419:3,055,420...3,062,131
JBrowse link
G Hyou1 hypoxia up-regulated 1 located_in ISO PMID:22665516 UniProt PMID:22665516 RGD:8553430 NCBI chrNW_004955412:20,149,104...20,161,378
Ensembl chrNW_004955412:20,148,953...20,161,172
JBrowse link
G Jph4 junctophilin 4 located_in ISO (PMID:17347645) MGI PMID:17347645 NCBI chrNW_004955409:36,785,003...36,795,196
Ensembl chrNW_004955409:36,785,003...36,795,196
JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 located_in ISO (PMID:17347645) MGI PMID:17347645 NCBI chrNW_004955408:34,223,523...34,366,191
Ensembl chrNW_004955408:34,109,334...34,368,114
JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 located_in ISO (PMID:16606357) MGI PMID:16606357 NCBI chrNW_004955442:15,498,909...15,545,298
Ensembl chrNW_004955442:15,498,909...15,545,298
JBrowse link
G Myo5a myosin VA is_active_in ISO (PMID:21151132) SynGO PMID:21151132 NCBI chrNW_004955409:2,409,503...2,530,539
Ensembl chrNW_004955409:2,428,815...2,530,012
JBrowse link
G Pdia3 protein disulfide isomerase family A member 3 located_in ISO PMID:22665516 UniProt PMID:22665516 RGD:8553430 NCBI chrNW_004955416:10,197,957...10,221,104
Ensembl chrNW_004955416:10,198,099...10,220,792
JBrowse link
G Pdia4 protein disulfide isomerase family A member 4 located_in ISO PMID:22665516 UniProt PMID:22665516 RGD:8553430 NCBI chrNW_004955491:4,344,874...4,360,205
Ensembl chrNW_004955491:4,344,874...4,360,205
JBrowse link
G Pdia6 protein disulfide isomerase family A member 6 located_in ISO PMID:22665516 UniProt PMID:22665516 RGD:8553430 NCBI chrNW_004955487:5,735,698...5,744,601
Ensembl chrNW_004955487:5,735,698...5,748,015
JBrowse link
G Plcb4 phospholipase C beta 4 located_in
is_active_in
ISO (PMID:15579147) MGI
SynGO
PMID:15579147 NCBI chrNW_004955415:19,108,120...19,462,084
Ensembl chrNW_004955415:19,310,917...19,463,098
JBrowse link
G Ppib peptidylprolyl isomerase B located_in ISO PMID:22665516 UniProt PMID:22665516 RGD:8553430 NCBI chrNW_004955450:11,241,279...11,246,628
Ensembl chrNW_004955450:11,241,279...11,249,056
JBrowse link
G Prdx4 peroxiredoxin 4 located_in ISO PMID:22665516 UniProt PMID:22665516 RGD:8553430 NCBI chrNW_004955509:4,111,501...4,132,529
Ensembl chrNW_004955509:4,116,379...4,132,529
JBrowse link
G Psen1 presenilin 1 located_in ISO (PMID:10508860), (PMID:9632714) CAFA PMID:9632714 PMID:10508860 NCBI chrNW_004955523:2,128,529...2,210,737
Ensembl chrNW_004955523:2,128,529...2,210,737
JBrowse link
G Rpl10 ribosomal protein L10 located_in ISO (PMID:10508860) CAFA PMID:10508860 NCBI chrNW_004955580:903,618...906,439
Ensembl chrNW_004955580:903,412...906,439
JBrowse link
G Rtn1 reticulon 1 located_in ISO PMID:23454728 MGI PMID:23454728 RGD:8693349 NCBI chrNW_004955466:13,290,419...13,454,387 JBrowse link
G Ryr1 ryanodine receptor 1 located_in ISO (PMID:23454728) MGI PMID:23454728 NCBI chrNW_004955468:879,807...1,000,118
Ensembl chrNW_004955468:879,951...1,000,036
JBrowse link
G Ryr2 ryanodine receptor 2 located_in ISO (PMID:23454728) MGI PMID:23454728 NCBI chrNW_004955492:2,647,597...3,275,512
Ensembl chrNW_004955492:2,648,956...3,076,509
JBrowse link
G Syvn1 synoviolin 1 located_in ISO (PMID:16186510) ParkinsonsUK-UCL PMID:16186510 NCBI chrNW_004955422:20,067,933...20,074,947
Ensembl chrNW_004955422:20,068,848...20,073,850
JBrowse link
G Th tyrosine hydroxylase located_in ISO (PMID:12457228) BHF-UCL PMID:12457228 NCBI chrNW_004955422:13,943,590...13,951,102
Ensembl chrNW_004955422:13,943,552...13,951,137
JBrowse link
smooth endoplasmic reticulum membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldob aldolase, fructose-bisphosphate B ISO RGD PMID:234468 RGD:2313431 NCBI chrNW_004955419:24,377,427...24,389,909
Ensembl chrNW_004955419:24,377,427...24,389,909
JBrowse link
G Ftcd formimidoyltransferase cyclodeaminase located_in ISO (PMID:14697341) BHF-UCL PMID:14697341 NCBI chrNW_004955407:42,608,249...42,617,167
Ensembl chrNW_004955407:42,607,872...42,617,166
JBrowse link
G Napepld N-acyl phosphatidylethanolamine phospholipase D is_active_in ISO (PMID:18234884) SynGO PMID:18234884 NCBI chrNW_004955410:8,217,684...8,233,302
Ensembl chrNW_004955410:8,220,400...8,247,486
JBrowse link
G Stx17 syntaxin 17 located_in ISO PMID:10930465 UniProt PMID:10930465 RGD:8553381 NCBI chrNW_004955419:25,674,771...25,741,357
Ensembl chrNW_004955419:25,674,771...25,741,355
JBrowse link
G Ttyh1 tweety family member 1 located_in ISO (PMID:20568244) MGI PMID:20568244 NCBI chrNW_004955567:1,523,534...1,538,963
Ensembl chrNW_004955567:1,523,534...1,538,963
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 12816
    cellular anatomical structure 12663
      endomembrane system 3208
        endoplasmic reticulum 1275
          smooth endoplasmic reticulum 31
            smooth endoplasmic reticulum cisterna + 0
            smooth endoplasmic reticulum lumen 0
            smooth endoplasmic reticulum membrane + 5
Path 2
Term Annotations click to browse term
  cellular_component 12816
    cellular anatomical structure 12663
      intracellular anatomical structure 10800
        intracellular organelle 9725
          intracellular membrane-bounded organelle 8804
            endoplasmic reticulum 1275
              smooth endoplasmic reticulum 31
                smooth endoplasmic reticulum cisterna + 0
                smooth endoplasmic reticulum lumen 0
                smooth endoplasmic reticulum membrane + 5
paths to the root