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ONTOLOGY REPORT - ANNOTATIONS

Term:TIM23 mitochondrial import inner membrane translocase complex
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Accession:GO:0005744 term browser browse the term
Definition:The protein transport machinery of the mitochondrial inner membrane that typically transports proteins that possess a matrix-targeting N-terminal presequence. The TIM23 complex contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transiently with the matrix heat-shock protein Hsp70 to form an ATP-driven import motor.
Comment:See also the cellular component term 'mitochondrial inner membrane ; GO:0005743'.
Synonyms:exact_synonym: mitochondrial inner membrane pre-sequence translocase complex;   mitochondrial inner membrane presequence translocase complex;   mitochondrial inner membrane translocase complex
 narrow_synonym: Tim23 complex


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TIM23 mitochondrial import inner membrane translocase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07030524.1 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002
G ENSRNOG00000067127 part_of IEA GO_REF:0000104 UniProt GO_REF:0000104
G Magmas-ps1 mitochondria-associated protein involved in granulocyte-macrophage colony-stimulating factor signal transduction, pseudogene 1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:88,602,379...88,602,899 JBrowse link
G Pam16 presequence translocase associated motor 16 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:10,942,534...10,950,654 JBrowse link
G Romo1 reactive oxygen species modulator 1 part_of ISO
IBA		 (PMID:30598479)
GO_REF:0000033		 RGD
GO_Central		 PMID:30598479 GO_REF:0000033 NCBI chr 3:165,119,794...165,121,394 JBrowse link
G Timm17a translocase of inner mitochondrial membrane 17A part_of IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(PMID:10339406), (PMID:30598479)		 Ensembl
GO_Central
RGD		 PMID:10339406 PMID:30598479 GO_REF:0000033 GO_REF:0000107 NCBI chr13:46,731,117...46,742,604 JBrowse link
G Timm17b translocase of inner mitochondrial membrane 17b part_of IBA
ISO		 GO_REF:0000033
(PMID:10339406), (PMID:30598479)		 GO_Central
RGD		 PMID:10339406 PMID:30598479 GO_REF:0000033 NCBI chr  X:14,596,330...14,603,491 JBrowse link
G Timm21 translocase of inner mitochondrial membrane 21 part_of ISS
IEA
IBA
ISO		 GO_REF:0000024
GO_REF:0000104
GO_REF:0000033
(PMID:23260140), (PMID:30598479)		 UniProt
GO_Central
RGD		 PMID:23260140 PMID:30598479 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 NCBI chr18:78,314,900...78,319,362 JBrowse link
G Timm23 translocase of inner mitochondrial membrane 23 part_of IEA
IBA
ISO		 GO_REF:0000002
GO_REF:0000033
(PMID:10339406), (PMID:30598479)		 InterPro
GO_Central
RGD		 PMID:10339406 PMID:30598479 GO_REF:0000002 GO_REF:0000033 NCBI chr16:7,410,308...7,436,392 JBrowse link
G Timm23-ps8 translocase of inner mitochondrial membrane 23, pseudogene 8 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:80,036,051...80,037,343 JBrowse link
G Timm23-ps8 translocase of inner mitochondrial membrane 23, pseudogene 8 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002
G Timm44 translocase of inner mitochondrial membrane 44 part_of IEA
ISO		 GO_REF:0000107
(PMID:30598479)		 Ensembl
RGD		 PMID:30598479 GO_REF:0000107 NCBI chr12:2,612,581...2,629,374 JBrowse link
G Timm50 translocase of inner mitochondrial membrane 50 part_of IBA
ISO		 GO_REF:0000033
UniProtKB:O14925 (PMID:15044455), (PMID:30598479)		 GO_Central
RGD		 PMID:15044455 PMID:30598479 GO_REF:0000033 NCBI chr 1:92,702,437...92,710,311 JBrowse link
PAM complex, Tim23 associated import motor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:59,594,314...59,658,862 JBrowse link
G Dnajc19 DnaJ heat shock protein family (Hsp40) member C19 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:116,923,272...116,945,312 JBrowse link
G Grpel1 GrpE-like 1, mitochondrial part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:74,292,023...74,298,243 JBrowse link
G Grpel2 GrpE-like 2, mitochondrial part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:55,167,831...55,180,073 JBrowse link
G Pam16 presequence translocase associated motor 16 part_of ISO SGD:S000003640 (PMID:20053669)
(PMID:24856930)		 RGD PMID:20053669 PMID:24856930 NCBI chr10:10,942,534...10,950,654 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21321
    protein-containing complex 6790
      mitochondrial protein-containing complex 180
        inner mitochondrial membrane protein complex 54
          TIM23 mitochondrial import inner membrane translocase complex 17
            PAM complex, Tim23 associated import motor 5
Path 2
Term Annotations click to browse term
  cellular_component 21321
    cellular anatomical structure 21026
      organelle 14240
        intracellular organelle 13828
          intracellular membrane-bounded organelle 12253
            mitochondrion 1991
              mitochondrial envelope 831
                mitochondrial membrane 774
                  mitochondrial inner membrane 475
                    inner mitochondrial membrane protein complex 54
                      TIM23 mitochondrial import inner membrane translocase complex 17
                        PAM complex, Tim23 associated import motor 5
paths to the root