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ONTOLOGY REPORT - ANNOTATIONS

Term:RNA polymerase I complex
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Accession:GO:0005736 term browser browse the term
Definition:RNA polymerase I, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces rRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase III and others of which are also found in RNA polymerases II and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.
Synonyms:exact_synonym: DNA-directed RNA polymerase I complex
 related_synonym: DNA-directed RNA polymerase I activity


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RNA polymerase I complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC109542.1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 1:196,570,210...196,573,077 JBrowse link
G Polr1a RNA polymerase I subunit A part_of IDA
IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000117
(PMID:15226435), (PMID:9236775)
(PMID:34671025), (PMID:36271492)		 GO_Central
UniProt
RGD		 PMID:9236775 PMID:15226435 PMID:34671025 PMID:36271492 PMID:9422795 GO_REF:0000033 GO_REF:0000117, RGD:2312782 NCBI chr 4:103,950,051...104,014,022
Ensembl chr 4:103,950,051...104,014,020 		JBrowse link
G Polr1b RNA polymerase I subunit B part_of IDA
IBA
ISO
IEA		 GO_REF:0000033
(PMID:9236775)
(PMID:34671025), (PMID:36271492)
GO_REF:0000107		 GO_Central
RGD
Ensembl		 PMID:9236775 PMID:34671025 PMID:36271492 PMID:9422795 GO_REF:0000033 GO_REF:0000107, RGD:2312782 NCBI chr 3:116,333,910...116,358,385
Ensembl chr 3:116,333,889...116,358,379 		JBrowse link
G Polr1c RNA polymerase I and III subunit C part_of ISO
IBA		 (PMID:34671025), (PMID:36271492)
GO_REF:0000033
(PMID:7929437)		 RGD
GO_Central		 PMID:7929437 PMID:34671025 PMID:36271492 GO_REF:0000033 NCBI chr 9:14,735,740...14,739,852
Ensembl chr 9:14,735,714...14,739,852 		JBrowse link
G Polr1d RNA polymerase I and III subunit D part_of ISO (PMID:34671025), (PMID:36271492)
(PMID:15226435)		 RGD PMID:15226435 PMID:34671025 PMID:36271492 NCBI chr12:7,970,592...8,004,157
Ensembl chr12:7,970,595...8,005,624 		JBrowse link
G Polr1e RNA polymerase I subunit E part_of ISO
IBA		 (PMID:16809778), (PMID:34671025), (PMID:36271492)
GO_REF:0000033
(PMID:8641287)		 RGD
GO_Central		 PMID:8641287 PMID:16809778 PMID:34671025 PMID:36271492 GO_REF:0000033 NCBI chr 5:59,279,456...59,295,346
Ensembl chr 5:59,279,460...59,295,369 		JBrowse link
G Polr1f RNA polymerase I subunit F part_of ISO
IBA		 (PMID:34671025), (PMID:36271492)
GO_REF:0000033		 RGD
GO_Central		 PMID:34671025 PMID:36271492 GO_REF:0000033 NCBI chr 6:50,053,289...50,070,514
Ensembl chr 6:50,053,289...50,070,514 		JBrowse link
G Polr1g RNA polymerase I subunit G part_of ISO
IBA		 (PMID:16809778), (PMID:34671025), (PMID:36271492)
GO_REF:0000033
(PMID:15226435)		 RGD
GO_Central		 PMID:15226435 PMID:16809778 PMID:34671025 PMID:36271492 GO_REF:0000033 NCBI chr 1:79,007,490...79,010,766
Ensembl chr 1:79,007,490...79,010,766 		JBrowse link
G Polr1h RNA polymerase I subunit H part_of ISO
IBA		 (PMID:34671025), (PMID:36271492)
GO_REF:0000033		 RGD
GO_Central		 PMID:34671025 PMID:36271492 GO_REF:0000033 NCBI chr20:1,594,936...1,598,854
Ensembl chr20:1,594,936...1,598,854 		JBrowse link
G Polr2e RNA polymerase II, I and III subunit E part_of IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(PMID:34671025), (PMID:36271492)		 Ensembl
GO_Central
RGD		 PMID:34671025 PMID:36271492 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:9,666,695...9,670,638
Ensembl chr 7:9,666,716...9,670,643 		JBrowse link
G Polr2f RNA polymerase II, I and III subunit F part_of TAS
IBA
ISO		 GO_REF:0000033
(PMID:34671025), (PMID:36271492)		 GO_Central
RGD		 PMID:34671025 PMID:36271492 PMID:10393248 GO_REF:0000033, RGD:1299534 NCBI chr 7:110,712,528...110,724,234
Ensembl chr 7:110,712,572...110,724,234 		JBrowse link
G Polr2h RNA polymerase II, I and III subunit H part_of ISO
IBA		 (PMID:34671025), (PMID:36271492)
GO_REF:0000033		 RGD
GO_Central		 PMID:34671025 PMID:36271492 GO_REF:0000033 NCBI chr11:80,192,017...80,197,468
Ensembl chr11:80,192,032...80,197,515
Ensembl chr10:80,192,032...80,197,515 		JBrowse link
G Polr2k RNA polymerase II, I and III subunit K part_of ISO
IBA		 (PMID:34671025), (PMID:36271492)
GO_REF:0000033		 RGD
GO_Central		 PMID:34671025 PMID:36271492 GO_REF:0000033 NCBI chr 7:67,347,118...67,359,466
Ensembl chr 7:67,356,113...67,357,668 		JBrowse link
G Polr2l RNA polymerase II, I and III subunit L part_of ISO
IBA		 (PMID:34671025), (PMID:36271492)
GO_REF:0000033		 RGD
GO_Central		 PMID:34671025 PMID:36271492 GO_REF:0000033 NCBI chr 1:196,570,051...196,572,060
Ensembl chr19:8,335,702...8,335,905 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20833
    protein-containing complex 6558
      nuclear protein-containing complex 1275
        nuclear DNA-directed RNA polymerase complex 99
          RNA polymerase I complex 14
Path 2
Term Annotations click to browse term
  cellular_component 20833
    cellular anatomical structure 20633
      organelle 13975
        membrane-bounded organelle 12560
          intracellular membrane-bounded organelle 12009
            nucleus 7454
              nuclear lumen 4056
                nucleolus 1023
                  RNA polymerase I complex 14
paths to the root