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ONTOLOGY REPORT - ANNOTATIONS

Term:DNA replication factor A complex
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Accession:GO:0005662 term browser browse the term
Definition:A conserved heterotrimeric complex that binds nonspecifically to single-stranded DNA and is required for multiple processes in eukaryotic DNA metabolism, including DNA replication, DNA repair, and recombination. In all eukaryotic organisms examined the complex is composed of subunits of approximately 70, 30, and 14 kDa.
Synonyms:exact_synonym: RPA;   replication protein A
 xref: Wikipedia:Replication_protein_A


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DNA replication factor A complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCAS2 BCAS2 pre-mRNA processing factor part_of
located_in		 IEA
ISO		 (PMID:24332808) Ensembl
UniProt		 PMID:24332808 GO_REF:0000107 NCBI chr 1:87,972,721...87,986,819
Ensembl chr 1:123,024,910...123,039,068 		JBrowse link
G CDC5L cell division cycle 5 like part_of
located_in		 IEA
ISO		 (PMID:24332808) Ensembl
UniProt		 PMID:24332808 GO_REF:0000107 NCBI chr 6:43,983,840...44,043,029
Ensembl chr 6:45,265,845...45,326,383 		JBrowse link
G ERCC5 ERCC excision repair 5, endonuclease located_in ISO (PMID:7700386) UniProt PMID:7700386 NCBI chr13:84,005,950...84,036,710
Ensembl chr13:103,096,344...103,174,182 		JBrowse link
G HELB DNA helicase B part_of
located_in		 IEA
ISO		 (PMID:26774285) Ensembl
UniProt		 PMID:26774285 GO_REF:0000107 NCBI chr12:22,571,448...22,607,417
Ensembl chr12:23,078,732...23,114,134 		JBrowse link
G PLRG1 pleiotropic regulator 1 part_of
located_in		 IEA
ISO		 (PMID:24332808) Ensembl
UniProt		 PMID:24332808 GO_REF:0000107 NCBI chr 4:146,900,494...146,917,016
Ensembl chr 4:158,719,568...158,735,103 		JBrowse link
G PRPF19 pre-mRNA processing factor 19 part_of
located_in		 IEA
ISO		 (PMID:24332808) Ensembl
UniProt		 PMID:24332808 GO_REF:0000107 NCBI chr11:56,153,965...56,169,821
Ensembl chr11:59,595,120...59,607,828 		JBrowse link
G RPA1 replication protein A1 part_of ISO
IEA		 RGD
Ensembl		 PMID:7503737 PMID:8463251 GO_REF:0000107 RGD:2307012 RGD:2307013 NCBI chr17:1,813,610...1,886,093
Ensembl chr17:1,705,380...1,775,596 		JBrowse link
G RPA2 replication protein A2 part_of ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:7503737 PMID:8463251 GO_REF:0000107 GO_REF:0000118 RGD:2307012 RGD:2307013 NCBI chr 1:27,151,784...27,175,110
Ensembl chr 1:28,191,731...28,214,666 		JBrowse link
G RPA3 replication protein A3 part_of ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:7503737 GO_REF:0000107 GO_REF:0000118 RGD:2307013 NCBI chr 7:8,361,623...8,365,098
Ensembl chr 7:7,713,629...7,717,169 		JBrowse link
G RPA4 replication protein A4 part_of ISO (PMID:19116208)
(PMID:7760808)		 UniProt
ComplexPortal		 PMID:7760808 PMID:19116208 NCBI chr  X:86,114,330...86,116,687 JBrowse link
G SMARCAL1 SNF2 related chromatin remodeling annealing helicase 1 part_of
located_in		 IEA
ISO		 (PMID:19793862), (PMID:19793863) Ensembl
UniProt		 PMID:19793862 PMID:19793863 GO_REF:0000107 NCBI chr2B:103,672,934...103,743,802
Ensembl chr2B:222,276,353...222,347,258 		JBrowse link
G TONSL tonsoku like, DNA repair protein part_of
located_in		 IEA
ISO		 (PMID:21055983) Ensembl
UniProt		 PMID:21055983 GO_REF:0000107 NCBI chr 8:141,195,959...141,211,849
Ensembl chr 8:144,185,674...144,201,040 		JBrowse link
G XPA XPA, DNA damage recognition and repair factor part_of
located_in		 IEA
ISO		 (PMID:7700386) Ensembl
UniProt		 PMID:7700386 GO_REF:0000107 NCBI chr 9:68,726,723...68,788,049
Ensembl chr 9:96,886,795...96,909,254 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20338
    protein-containing complex 7911
      nuclear protein-containing complex 2598
        DNA replication factor A complex 13
Path 2
Term Annotations click to browse term
  cellular_component 20338
    cellular anatomical structure 19904
      organelle 14886
        membrane-bounded organelle 13437
          intracellular membrane-bounded organelle 12902
            nucleus 8768
              nuclear lumen 4566
                nuclear chromosome 224
                  nuclear replication fork 37
                    nuclear replisome 22
                      DNA replication factor A complex 13
paths to the root