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ONTOLOGY REPORT - ANNOTATIONS

Term:nuclear lamina
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Accession:GO:0005652 term browser browse the term
Definition:The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a cell nucleus, composed of lamin filaments. The polypeptides of the lamina are thought to be concerned in the dissolution of the nuclear envelope and its re-formation during mitosis. The lamina is composed of lamin A and lamin C filaments cross-linked into an orthogonal lattice, which is attached via lamin B to the inner nuclear membrane through interactions with a lamin B receptor, an IFAP, in the membrane.
Synonyms:xref: NIF_Subcellular:sao1455996588;   Wikipedia:Nuclear_lamina


show annotations for term's descendants           Sort by:
nuclear lamina term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cask calcium/calmodulin dependent serine protein kinase located_in
part_of 		ISO (PMID:18664494) RGD PMID:18664494 NCBI chr  X:11,572,328...11,915,831
Ensembl chr  X:11,572,636...11,911,948 		JBrowse link
G Efcc1 EF-hand and coiled-coil domain containing 1 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:121,745,547...121,778,475
Ensembl chr 4:121,745,633...121,775,220 		JBrowse link
G ENSRNOG00000063631 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044
G Hlcs holocarboxylase synthetase located_in ISO
IEA 		(PMID:14613969)
GO_REF:0000107 		RGD
Ensembl		 PMID:14613969 GO_REF:0000107 NCBI chr11:46,925,491...47,123,111
Ensembl chr11:46,925,491...47,105,082 		JBrowse link
G Lbr lamin B receptor is_active_in IEA
ISO 		GO_REF:0000107
(PMID:27492478) 		Ensembl
RGD		 PMID:27492478 GO_REF:0000107 NCBI chr13:96,071,058...96,095,709
Ensembl chr13:96,071,081...96,095,709 		JBrowse link
G Lmna lamin A/C located_in
is_active_in 		IEA
ISS
IBA
ISO 		GO_REF:0000044
GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(PMID:2188730), (PMID:2344612), (PMID:24741066), (PMID:31548606), (PMID:37788673), (PMID:37832547)
(PMID:28241138), (PMID:31576060) 		UniProt
GO_Central
Ensembl
RGD		 PMID:2188730 PMID:2344612 PMID:24741066 PMID:28241138 PMID:31548606 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000044 GO_REF:0000107 NCBI chr 2:176,237,564...176,265,301
Ensembl chr 2:176,237,564...176,288,072 		JBrowse link
G Lmnb1 lamin B1 located_in
is_active_in 		IDA
ISO
IEA
IBA 		(PMID:32910914)
GO_REF:0000117
GO_REF:0000033
GO_REF:0000107
GO_REF:0000044
(PMID:28241138) 		RGD
UniProt
GO_Central
Ensembl		 PMID:28241138 PMID:32910914 PMID:16950509 GO_REF:0000033 GO_REF:0000044 GO_REF:0000107 GO_REF:0000117, RGD:10044252 NCBI chr18:52,373,939...52,413,284
Ensembl chr18:52,373,757...52,413,283 		JBrowse link
G Lmnb2 lamin B2 is_active_in IBA
ISO 		GO_REF:0000033
(PMID:28241138) 		GO_Central
RGD		 PMID:28241138 GO_REF:0000033 NCBI chr 7:9,443,308...9,459,468
Ensembl chr 7:9,440,128...9,459,342 		JBrowse link
G Nup35 nucleoporin 35 IDA RGD PMID:15703211 RGD:7327145 NCBI chr 3:85,965,907...85,991,659
Ensembl chr 3:85,945,080...85,992,027 		JBrowse link
G Pcna proliferating cell nuclear antigen located_in IEA
ISO 		GO_REF:0000107
(PMID:10888872) 		Ensembl
RGD		 PMID:10888872 GO_REF:0000107 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901 		JBrowse link
G Rnf220 ring finger protein 220 located_in ISO
IEA 		(PMID:33964137)
GO_REF:0000107 		RGD
Ensembl		 PMID:33964137 GO_REF:0000107 NCBI chr 5:135,975,739...136,198,017
Ensembl chr 5:135,975,739...136,197,858 		JBrowse link
G Stx1b syntaxin 1B located_in ISO (PMID:18691641) RGD PMID:18691641 NCBI chr 1:191,846,016...191,864,878
Ensembl chr 1:191,833,743...191,871,633 		JBrowse link
G Suv39h1 SUV39H1 histone lysine methyltransferase located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr  X:17,093,059...17,105,942
Ensembl chr  X:17,092,986...17,105,942 		JBrowse link
lamin filament term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif6 eukaryotic translation initiation factor 6 located_in ISO (PMID:9374518) RGD PMID:9374518 NCBI chr 3:164,785,162...164,791,410
Ensembl chr 3:164,785,163...164,791,525 		JBrowse link
G Lmna lamin A/C located_in ISO (PMID:8032679) RGD PMID:8032679 NCBI chr 2:176,237,564...176,265,301
Ensembl chr 2:176,237,564...176,288,072 		JBrowse link
G Lmnb1 lamin B1 located_in IEA
ISO 		GO_REF:0000107
(PMID:8032679) 		Ensembl
RGD		 PMID:8032679 GO_REF:0000107 NCBI chr18:52,373,939...52,413,284
Ensembl chr18:52,373,757...52,413,283 		JBrowse link
G Lmnb2 lamin B2 located_in ISO (PMID:8032679) RGD PMID:8032679 NCBI chr 7:9,443,308...9,459,468
Ensembl chr 7:9,440,128...9,459,342 		JBrowse link
G Lmntd2 lamin tail domain containing 2 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:205,744,694...205,750,460
Ensembl chr 1:205,744,697...205,748,738 		JBrowse link
G Narf nuclear prelamin A recognition factor located_in
is_active_in 		ISO
IBA 		(PMID:10514485)
GO_REF:0000033 		RGD
GO_Central		 PMID:10514485 GO_REF:0000033 NCBI chr10:107,017,344...107,035,777
Ensembl chr10:107,016,510...107,037,283 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19485
    cellular anatomical structure 19353
      nuclear lamina 16
        lamin filament 6
Path 2
Term Annotations click to browse term
  cellular_component 19485
    cellular anatomical structure 19353
      organelle 13686
        membrane-bounded organelle 12471
          intracellular membrane-bounded organelle 11899
            nucleus 7471
              nuclear lumen 4263
                nuclear periphery 33
                  nuclear lamina 16
                    lamin filament 6
paths to the root