ONTOLOGY REPORT - ANNOTATIONS
Term: D-glucose:sodium symporter activity
Accession: GO:0005412
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Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-glucose(out) + Na+(out) = D-glucose(in) + Na+(in).
Synonyms: exact_synonym: glucose:sodium symporter activity
xref: MetaCyc:RXN-22596; Reactome:R-HSA-5656356 "Defective SLC5A1 does not cotransport Glc and Na+"; Reactome:R-HSA-5658163 "Defective SLC5A2 does not cotransport Glc and Na+ from extracellular region to cytosol"; reactome:R-HSA-189208 "SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol"; reactome:R-HSA-429613 "SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol"; reactome:R-HSA-8932955 "SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol"
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Slc5a1
solute carrier family 5 member 1
enables
TAS IDA ISO IBA
(PMID:20980548), (PMID:34880492), (PMID:35077764), (PMID:8563765), (PMID:8836035) GO_REF:0000033 (PMID:22124465)
RGD GO_Central
PMID:8563765 PMID:8836035 PMID:20980548 PMID:22124465 PMID:34880492 PMID:35077764 PMID:11831390 PMID:15829715 More...
GO_REF:0000033, RGD:730194 , RGD:1624261
NCBI chr14:77,553,990...77,618,589
Ensembl chr14:77,553,843...77,618,547
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Slc5a10
solute carrier family 5 member 10
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr10:46,352,060...46,400,795
Ensembl chr10:46,352,061...46,399,811
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Slc5a11
solute carrier family 5 member 11
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:177,735,511...177,795,193
Ensembl chr 1:177,756,561...177,795,193
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Slc5a1l1
solute carrier family 5 member 1 like 1
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr20:12,664,388...12,713,968
Ensembl chr20:12,664,387...12,713,716
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Slc5a2
solute carrier family 5 member 2
enables
IDA IEA ISO IBA
GO_REF:0000107 (PMID:11133510), (PMID:20980548), (PMID:28592437) GO_REF:0000033
Ensembl RGD GO_Central
PMID:11133510 PMID:20980548 PMID:28592437 PMID:7493971 PMID:14506074
GO_REF:0000033 GO_REF:0000107, RGD:633997 , RGD:1599050
NCBI chr 1:182,847,185...182,853,309
Ensembl chr 1:182,847,106...182,853,306
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Slc5a3
solute carrier family 5 member 3
enables
ISO IBA
(PMID:7537337) GO_REF:0000033
RGD GO_Central
PMID:7537337
GO_REF:0000033
NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883
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Slc5a4
solute carrier family 5 member 4
NOT|enables
ISO IBA
(PMID:13130073), (PMID:20421923), (PMID:22766068) (PMID:8077195) GO_REF:0000033 (PMID:20392930) (PMID:22301059)
RGD GO_Central
PMID:8077195 PMID:13130073 PMID:20392930 PMID:20421923 PMID:22301059 PMID:22766068 More...
GO_REF:0000033
NCBI chr20:12,475,644...12,518,738
Ensembl chr20:12,475,644...12,518,738
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Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr20:12,559,545...12,609,133
Ensembl chr20:12,559,545...12,608,422
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Slc5a9
solute carrier family 5 member 9
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 5:126,709,762...126,733,468
Ensembl chr 5:126,709,769...126,733,468
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Slc5a4
solute carrier family 5 member 4
enables
ISO
(PMID:13130073)
RGD
PMID:13130073
NCBI chr20:12,475,644...12,518,738
Ensembl chr20:12,475,644...12,518,738
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Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
enables
IEA
GO_REF:0000107
Ensembl
GO_REF:0000107
NCBI chr20:12,559,545...12,609,133
Ensembl chr20:12,559,545...12,608,422
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