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ONTOLOGY REPORT - ANNOTATIONS


Term:D-glucose:sodium symporter activity
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Accession:GO:0005412 term browser browse the term
Definition:Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-glucose(out) + Na+(out) = D-glucose(in) + Na+(in).
Synonyms:exact_synonym: glucose:sodium symporter activity
 xref: MetaCyc:RXN-22596;   Reactome:R-HSA-5656356 "Defective SLC5A1 does not cotransport Glc and Na+";   Reactome:R-HSA-5658163 "Defective SLC5A2 does not cotransport Glc and Na+ from extracellular region to cytosol";   reactome:R-HSA-189208 "SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol";   reactome:R-HSA-429613 "SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol";   reactome:R-HSA-8932955 "SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol"



show annotations for term's descendants           Sort by:
D-glucose:sodium symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc5a1 solute carrier family 5 member 1 enables TAS
IDA
ISO
IBA
(PMID:20980548), (PMID:34880492), (PMID:35077764), (PMID:8563765), (PMID:8836035)
GO_REF:0000033
(PMID:22124465)
RGD
GO_Central
PMID:8563765 PMID:8836035 PMID:20980548 PMID:22124465 PMID:34880492 More... GO_REF:0000033, RGD:730194, RGD:1624261 NCBI chr14:77,553,990...77,618,589
Ensembl chr14:77,553,843...77,618,547
JBrowse link
G Slc5a10 solute carrier family 5 member 10 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:46,352,060...46,400,795
Ensembl chr10:46,352,061...46,399,811
JBrowse link
G Slc5a11 solute carrier family 5 member 11 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:177,735,511...177,795,193
Ensembl chr 1:177,756,561...177,795,193
JBrowse link
G Slc5a1l1 solute carrier family 5 member 1 like 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:12,664,388...12,713,968
Ensembl chr20:12,664,387...12,713,716
JBrowse link
G Slc5a2 solute carrier family 5 member 2 enables IDA
IEA
ISO
IBA
GO_REF:0000107
(PMID:11133510), (PMID:20980548), (PMID:28592437)
GO_REF:0000033
Ensembl
RGD
GO_Central
PMID:11133510 PMID:20980548 PMID:28592437 PMID:7493971 PMID:14506074 GO_REF:0000033 GO_REF:0000107, RGD:633997, RGD:1599050 NCBI chr 1:182,847,185...182,853,309
Ensembl chr 1:182,847,106...182,853,306
JBrowse link
G Slc5a3 solute carrier family 5 member 3 enables ISO
IBA
(PMID:7537337)
GO_REF:0000033
RGD
GO_Central
PMID:7537337 GO_REF:0000033 NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883
JBrowse link
G Slc5a4 solute carrier family 5 member 4 NOT|enables ISO
IBA
(PMID:13130073), (PMID:20421923), (PMID:22766068)
(PMID:8077195)
GO_REF:0000033
(PMID:20392930)
(PMID:22301059)
RGD
GO_Central
PMID:8077195 PMID:13130073 PMID:20392930 PMID:20421923 PMID:22301059 More... GO_REF:0000033 NCBI chr20:12,475,644...12,518,738
Ensembl chr20:12,475,644...12,518,738
JBrowse link
G Slc5a4b solute carrier family 5 (neutral amino acid transporters, system A), member 4b enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:12,559,545...12,609,133
Ensembl chr20:12,559,545...12,608,422
JBrowse link
G Slc5a9 solute carrier family 5 member 9 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:126,709,762...126,733,468
Ensembl chr 5:126,709,769...126,733,468
JBrowse link
low-affinity D-glucose:sodium symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc5a4 solute carrier family 5 member 4 enables ISO (PMID:13130073) RGD PMID:13130073 NCBI chr20:12,475,644...12,518,738
Ensembl chr20:12,475,644...12,518,738
JBrowse link
G Slc5a4b solute carrier family 5 (neutral amino acid transporters, system A), member 4b enables IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:12,559,545...12,609,133
Ensembl chr20:12,559,545...12,608,422
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21088
    transporter activity 1269
      transmembrane transporter activity 1162
        carbohydrate transmembrane transporter activity 38
          carbohydrate:monoatomic cation symporter activity 15
            D-glucose:sodium symporter activity 9
              low-affinity D-glucose:sodium symporter activity 2
Path 2
Term Annotations click to browse term
  molecular_function 21088
    transporter activity 1269
      transmembrane transporter activity 1162
        monoatomic ion transmembrane transporter activity 770
          monoatomic cation transmembrane transporter activity 651
            metal ion transmembrane transporter activity 462
              sodium ion transmembrane transporter activity 174
                solute:sodium symporter activity 85
                  D-glucose:sodium symporter activity 9
                    low-affinity D-glucose:sodium symporter activity 2
paths to the root