Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:serotonin:sodium:chloride symporter activity
go back to main search page
Accession:GO:0005335 term browser browse the term
Definition:Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: serotonin(out) + Na+(out) + Cl-(out) = serotonin(in) + Na+(in)+ Cl-(in).
Synonyms:exact_synonym: serotonin transmembrane transporter activity
 related_synonym: serotonin:sodium symporter activity
 alt_id: GO:0005336;   GO:0015222
 xref: RHEA:51196;   TC:2.A.22.1.1;   reactome:R-HSA-444008 "SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol"


show annotations for term's descendants           Sort by:
serotonin:sodium:chloride symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc18a1 solute carrier family 18 member A1 enables IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:16926160 GO_REF:0000033, RGD:5130998 NCBI chr16:20,653,268...20,687,051
Ensembl chr16:20,653,508...20,687,051 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 enables TAS
IMP
IDA
ISO
IBA		 PMID:11709063
PMID:10716733
PMID:8601815
PMID:15627510
PMID:10407194
PMID:1944572
(PMID:10407194), (PMID:12869649), (PMID:17506858), (PMID:8987735)
GO_REF:0000033
(PMID:9037532)		 RGD
GO_Central		 PMID:8987735 PMID:9037532 PMID:10407194 PMID:12869649 PMID:17506858 More... GO_REF:0000033, RGD:730261, RGD:1580635, RGD:8553990, RGD:8554226, RGD:155663514, RGD:8553308, RGD:155663546, RGD:155663539 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20633
    transporter activity 1253
      transmembrane transporter activity 1153
        organic hydroxy compound transmembrane transporter activity 53
          serotonin:sodium:chloride symporter activity 3
Path 2
Term Annotations click to browse term
  molecular_function 20633
    transporter activity 1253
      transmembrane transporter activity 1153
        active transmembrane transporter activity 447
          secondary active transmembrane transporter activity 291
            symporter activity 141
              solute:monoatomic cation symporter activity 113
                monoatomic anion:monoatomic cation symporter activity 26
                  monoatomic anion:sodium symporter activity 19
                    sodium:chloride symporter activity 17
                      serotonin:sodium:chloride symporter activity 3
paths to the root