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ONTOLOGY REPORT - ANNOTATIONS

Term:norepinephrine:sodium symporter activity
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Accession:GO:0005334 term browser browse the term
Definition:Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: norepinephrine(out) + Na+(out) + Cl-(out) = norepinephrine(in) + Na+(in) + Cl-(in).
Synonyms:exact_synonym: levarterenol transporter activity;   noradrenaline transporter activity;   norepinephrine transmembrane transporter activity;   norepinephrine:sodium:chloride symporter activity
 alt_id: GO:0005333
 xref: Reactome:R-HSA-5659764 "Defective SLC6A2 does not cotransport NAd, Na+ from extracellular region to cytosol";   Wikipedia:Norepinephrine_transporter;   reactome:R-HSA-443997 "SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol"


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norepinephrine:sodium symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a1 solute carrier family 22 member 1 IDA RGD PMID:9776363 RGD:1643122 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678 		JBrowse link
G Slc6a2 solute carrier family 6 member 2 enables IDA
ISO
IBA		 (PMID:2008212), (PMID:8125921)
GO_REF:0000033
(PMID:16269905)		 RGD
GO_Central		 PMID:2008212 PMID:8125921 PMID:16269905 PMID:10196144 GO_REF:0000033, RGD:634151 NCBI chr19:14,010,292...14,055,317
Ensembl chr19:14,010,386...14,050,357 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 enables IDA
IBA		 PMID:8125921
GO_REF:0000033		 GO_Central PMID:8125921 GO_REF:0000033, RGD:152995566 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20634
    transporter activity 1253
      transmembrane transporter activity 1153
        organic cation transmembrane transporter activity 83
          norepinephrine:sodium symporter activity 3
Path 2
Term Annotations click to browse term
  molecular_function 20634
    transporter activity 1253
      transmembrane transporter activity 1153
        monoatomic ion transmembrane transporter activity 762
          monoatomic cation transmembrane transporter activity 642
            metal ion transmembrane transporter activity 456
              sodium ion transmembrane transporter activity 165
                solute:sodium symporter activity 81
                  monoatomic anion:sodium symporter activity 19
                    sodium:chloride symporter activity 17
                      norepinephrine:sodium symporter activity 3
paths to the root