Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:gamma-aminobutyric acid:sodium:chloride symporter activity
go back to main search page
Accession:GO:0005332 term browser browse the term
Definition:Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + Na+(out) + Cl-(out) = gamma-aminobutyric acid(in) + Na+(in) + Cl(in).
Comment:See also the molecular function term 'neurotransmitter:sodium symporter activity ; GO:0005328'.
Synonyms:exact_synonym: 4-aminobutanoate:sodium symporter activity;   4-aminobutyrate:sodium symporter activity;   GABA:sodium symporter activity;   betaine/GABA:sodium symporter activity;   gamma-aminobutyric acid:sodium symporter activity
 broad_synonym: sodium/chloride-dependent GABA transporter activity
 xref: TC:2.A.22.3.2;   reactome:R-HSA-444007 "GAT1-3 mediate Na+/Cl- dependent GABA transport"


show annotations for term's descendants           Sort by:
gamma-aminobutyric acid:sodium:chloride symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc6a1 solute carrier family 6 member 1 enables IDA
ISO
IBA		 (PMID:10973981), (PMID:30132828)
PMID:21775701
PMID:18054861
GO_REF:0000033
(PMID:16150932), (PMID:30270321), (PMID:8420981)		 RGD
GO_Central		 PMID:8420981 PMID:10973981 PMID:16150932 PMID:30132828 PMID:30270321 More... GO_REF:0000033, RGD:632739, RGD:152025506, RGD:152025510 NCBI chr 4:147,448,961...147,482,295
Ensembl chr 4:147,466,965...147,482,293 		JBrowse link
G Slc6a11 solute carrier family 6 member 11 enables IDA
ISO
IBA		 PMID:1497897
(PMID:7874447)
GO_REF:0000033
(PMID:30270321), (PMID:8420981)		 RGD
GO_Central		 PMID:7874447 PMID:8420981 PMID:30270321 PMID:1400419 PMID:1497897 GO_REF:0000033, RGD:727560, RGD:729938 NCBI chr 4:147,297,972...147,413,319
Ensembl chr 4:147,297,969...147,413,443 		JBrowse link
G Slc6a12 solute carrier family 6 member 12 enables TAS
IEA
ISO
ISS
IBA		 GO_REF:0000002
(PMID:7589472), (PMID:7861179)
(PMID:10358010)
GO_REF:0000024
GO_REF:0000033
(PMID:1517200)		 InterPro
RGD
UniProt
GO_Central		 PMID:1517200 PMID:7589472 PMID:7861179 PMID:10358010 PMID:15073174 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033, RGD:1303365 NCBI chr 4:154,585,386...154,603,750
Ensembl chr 4:154,585,500...154,603,750 		JBrowse link
G Slc6a13 solute carrier family 6 member 13 enables IDA
IEA
ISO
IBA		 GO_REF:0000002
PMID:22896705
GO_REF:0000107
(PMID:17502375), (PMID:22932902)
GO_REF:0000033
(PMID:22896705), (PMID:30270321), (PMID:8420981)		 InterPro
Ensembl
RGD
GO_Central		 PMID:8420981 PMID:17502375 PMID:22896705 PMID:22932902 PMID:30270321 More... GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:727560, RGD:152025533 NCBI chr 4:154,539,246...154,577,784
Ensembl chr 4:154,540,468...154,576,152 		JBrowse link
G Slc6a6 solute carrier family 6 member 6 enables IEA
IDA
IBA
ISO		 GO_REF:0000107
PMID:18501699
GO_REF:0000033
(PMID:30270321)		 Ensembl
GO_Central
RGD		 PMID:30270321 PMID:18501699 GO_REF:0000033 GO_REF:0000107, RGD:30309916 NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875 		JBrowse link
G Slc6a8 solute carrier family 6 member 8 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:151,384,675...151,393,979
Ensembl chr  X:151,384,675...151,393,979 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21086
    transporter activity 1269
      transmembrane transporter activity 1162
        amino acid transmembrane transporter activity 107
          gamma-aminobutyric acid transmembrane transporter activity 9
            gamma-aminobutyric acid:sodium:chloride symporter activity 6
Path 2
Term Annotations click to browse term
  molecular_function 21086
    transporter activity 1269
      transmembrane transporter activity 1162
        monoatomic ion transmembrane transporter activity 770
          monoatomic cation transmembrane transporter activity 651
            metal ion transmembrane transporter activity 462
              sodium ion transmembrane transporter activity 174
                solute:sodium symporter activity 85
                  organic acid:sodium symporter activity 36
                    monocarboxylate:sodium symporter activity 15
                      gamma-aminobutyric acid:sodium:chloride symporter activity 6
paths to the root