Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:long-chain fatty acid transmembrane transporter activity
go back to main search page
Accession:GO:0005324 term browser browse the term
Definition:Enables the transfer of a long-chain fatty acid from one side of a membrane to the other. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.
Comment:While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
Synonyms:related_synonym: long-chain fatty acid transporter activity
 alt_id: GO:0005325;   GO:0008562
 xref: RHEA:39283;   Reactome:R-HSA-434381 "CD36 (FAT) translocates palmitate from the extracellular region to the cytosol";   Reactome:R-HSA-5684043 "Defective ABCD1 does not transfer LCFAs from cytosol to peroxisomal matrix";   reactome:R-HSA-2046087 "Translocation of tetracosahexaenoyl-CoA to peroxisomes";   reactome:R-HSA-2046093 "Translocation of tetracosapentaenoyl-CoA to peroxisomes";   reactome:R-HSA-382575 "ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix"



show annotations for term's descendants           Sort by:
long-chain fatty acid transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 IDA leukotriene LTC4 transporter RGD PMID:12867490 RGD:2303048 NCBI chr10:1,022,041...1,162,431 JBrowse link
G Abcd1 ATP binding cassette subfamily D member 1 enables ISO
IBA
ISS
UniProtKB:P34230|UniProtKB:P41909 (PMID:11500517), (PMID:18757502)
GO_REF:0000033
GO_REF:0000024
RGD
GO_Central
UniProt
PMID:11500517 PMID:18757502 GO_REF:0000024 GO_REF:0000033 NCBI chr  X:151,428,334...151,450,115 JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:122,263,034...122,311,642 JBrowse link
G Abcd3 ATP binding cassette subfamily D member 3 enables ISO
ISS
IEA
IBA
(PMID:24333844)
GO_REF:0000024
GO_REF:0000002
GO_REF:0000033
RGD
UniProt
InterPro
GO_Central
PMID:24333844 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 NCBI chr 2:212,536,791...212,590,379 JBrowse link
G Cd36 CD36 molecule enables ISO (PMID:21395585) RGD PMID:21395585 NCBI chr 4:18,209,088...18,302,142 JBrowse link
G Fabp1 fatty acid binding protein 1 IMP transfer of 12-(9-anthroyloxy)oleic acid to phospholipid membranes RGD PMID:15035630 RGD:1582395 NCBI chr 4:104,744,302...104,753,119 JBrowse link
G Fabp2 fatty acid binding protein 2 IDA RGD PMID:16551626 RGD:1582384 NCBI chr 2:211,040,032...211,044,089 JBrowse link
G Fabp3 fatty acid binding protein 3 IPI RGD PMID:8573586 RGD:1582409 NCBI chr 5:142,651,962...142,658,707 JBrowse link
G Fabp4 fatty acid binding protein 4 enables ISS
ISO
GO_REF:0000024
(PMID:12077340)
UniProt
RGD
PMID:12077340 GO_REF:0000024 NCBI chr 2:93,488,251...93,492,961 JBrowse link
G Fabp5 fatty acid binding protein 5 enables ISO (PMID:21395585) RGD PMID:21395585 NCBI chr 2:91,765,056...91,768,716 JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid enables ISO (PMID:26005865)
(PMID:27008858)
RGD PMID:26005865 PMID:27008858 NCBI chr 5:140,510,933...140,525,828 JBrowse link
G Slc27a1 solute carrier family 27 member 1 enables ISO
IBA
IEA
(PMID:21395585), (PMID:28035674), (PMID:31091338)
GO_REF:0000033
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:21395585 PMID:28035674 PMID:31091338 GO_REF:0000033 GO_REF:0000107 NCBI chr16:18,278,984...18,300,173 JBrowse link
G Slc27a2 solute carrier family 27 member 2 enables IEA
ISO
IBA
GO_REF:0000107
(PMID:15699031), (PMID:20530735)
GO_REF:0000033
(PMID:20530735), (PMID:21768100)
Ensembl
RGD
GO_Central
PMID:15699031 PMID:20530735 PMID:21768100 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:113,804,728...113,842,208 JBrowse link
G Slc27a4 solute carrier family 27 member 4 enables ISO
IBA
(PMID:21395585)
GO_REF:0000033
RGD
GO_Central
PMID:21395585 GO_REF:0000033 NCBI chr 3:13,075,022...13,087,943 JBrowse link
G Slc27a5 solute carrier family 27 member 5 enables ISO
IBA
ISS
(PMID:20530735)
GO_REF:0000033
GO_REF:0000024
RGD
GO_Central
UniProt
PMID:20530735 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:82,688,742...82,699,335 JBrowse link
G Slc27a6 solute carrier family 27 member 6 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:54,238,697...54,297,595 JBrowse link
G Slc2a1 solute carrier family 2 member 1 enables ISO (PMID:10227690) RGD PMID:10227690 NCBI chr 5:138,002,522...138,030,742 JBrowse link
oleate transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule enables ISO
IEA
(PMID:24503477)
GO_REF:0000107
RGD
Ensembl
PMID:24503477 GO_REF:0000107 NCBI chr 4:18,209,088...18,302,142 JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid enables ISO (PMID:26005865) RGD PMID:26005865 NCBI chr 5:140,510,933...140,525,828 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21086
    transporter activity 1269
      lipid transporter activity 180
        lipid transmembrane transporter activity 55
          fatty acid transmembrane transporter activity 20
            long-chain fatty acid transmembrane transporter activity 17
              arachidonate transmembrane transporter activity 0
              long-chain fatty acid transporting porin activity 0
              oleate transmembrane transporter activity 2
Path 2
Term Annotations click to browse term
  molecular_function 21086
    transporter activity 1269
      transmembrane transporter activity 1162
        organic acid transmembrane transporter activity 193
          carboxylic acid transmembrane transporter activity 192
            monocarboxylic acid transmembrane transporter activity 71
              fatty acid transmembrane transporter activity 20
                long-chain fatty acid transmembrane transporter activity 17
                  arachidonate transmembrane transporter activity 0
                  long-chain fatty acid transporting porin activity 0
                  oleate transmembrane transporter activity 2
paths to the root