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ONTOLOGY REPORT - ANNOTATIONS

Term:delayed rectifier potassium channel activity
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Accession:GO:0005251 term browser browse the term
Definition:Enables the transmembrane transfer of a potassium ion by a delayed rectifying voltage-gated channel. A delayed rectifying current-voltage relation is one where channel activation kinetics are time-dependent, and inactivation is slow.
Synonyms:xref: reactome:R-HSA-5577050 "AKAP9:KCNQ1 tetramer:KCNE dimer transports K+ from cytosol to extracellular region";   reactome:R-HSA-5577237 "KCNH2:KCNE transport K+ from cytosol to extracellular region"


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delayed rectifier potassium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcna1 potassium voltage-gated channel subfamily A member 1 enables IMP
ISS
IDA
ISO
IBA		 GO_REF:0000024
PMID:22206926
PMID:8038169
(PMID:19912772), (PMID:8845167)
GO_REF:0000033
(PMID:15361858)		 UniProt
RGD
GO_Central		 PMID:8845167 PMID:15361858 PMID:19912772 PMID:14602579 PMID:22206926 More... GO_REF:0000024 GO_REF:0000033, RGD:1300201, RGD:10047237, RGD:10047389 NCBI chr 4:159,464,223...159,472,905
Ensembl chr 4:159,464,188...159,472,682 		JBrowse link
G Kcna10 potassium voltage-gated channel subfamily A member 10 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:194,786,500...194,798,575
Ensembl chr 2:194,786,500...194,798,575 		JBrowse link
G Kcna2 potassium voltage-gated channel subfamily A member 2 enables IMP
IBA		 PMID:19713757
GO_REF:0000033		 GO_Central PMID:19713757 GO_REF:0000033, RGD:10047171 NCBI chr 2:194,704,555...194,718,387
Ensembl chr 2:194,704,639...194,718,400 		JBrowse link
G Kcna3 potassium voltage-gated channel subfamily A member 3 enables IMP
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:14602579 GO_REF:0000033, RGD:1300201 NCBI chr 2:194,632,106...194,634,059
Ensembl chr 2:194,632,196...194,650,138 		JBrowse link
G Kcna4 potassium voltage-gated channel subfamily A member 4 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:93,756,399...93,778,004
Ensembl chr 3:93,756,446...93,769,162 		JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 enables ISO
ISS
IDA
IBA		 (PMID:12130714), (PMID:19343045), (PMID:1986382)
GO_REF:0000024
PMID:15618540
GO_REF:0000033		 RGD
UniProt
GO_Central		 PMID:1986382 PMID:12130714 PMID:19343045 PMID:15618540 GO_REF:0000024 GO_REF:0000033, RGD:10047274 NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697 		JBrowse link
G Kcna6 potassium voltage-gated channel subfamily A member 6 enables IDA
ISO
IEA
IBA		 PMID:15618540
(PMID:2347305)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:2347305 PMID:15618540 GO_REF:0000033 GO_REF:0000107, RGD:10047274 NCBI chr 4:159,542,941...159,576,189
Ensembl chr 4:159,542,615...159,576,189 		JBrowse link
G Kcna7 potassium voltage-gated channel subfamily A member 7 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:95,886,073...95,891,565
Ensembl chr 1:95,886,073...95,891,565 		JBrowse link
G Kcnb1 potassium voltage-gated channel subfamily B member 1 enables
NOT|enables		 IDA
IMP
IEA
ISO		 PMID:20202934
GO_REF:0000107
PMID:19690160
PMID:9305895
PMID:12954870
PMID:19219384
PMID:19077057
(PMID:10484328), (PMID:11852086), (PMID:1283219), (PMID:19074135), (PMID:19223394), (PMID:8081723)
PMID:2206531
PMID:8978827
PMID:7576642
PMID:9362476
PMID:9565597
PMID:2770868
PMID:9351973
PMID:1875913
PMID:12560340
PMID:8083226
PMID:12065754
PMID:8980147
(PMID:17767909), (PMID:2002364), (PMID:22056818), (PMID:24494598)		 Ensembl
RGD		 PMID:1283219 PMID:2002364 PMID:8081723 PMID:10484328 PMID:11852086 More... GO_REF:0000107, RGD:2303541, RGD:2303542, RGD:10047337, RGD:10047295, RGD:737625, RGD:10047250, RGD:7243947, RGD:10047372, RGD:405650234, RGD:150527856, RGD:405650276, RGD:729206, RGD:1299426, RGD:728957, RGD:405650260, RGD:405650251, RGD:405650382, RGD:405650235, RGD:405650315, RGD:10047188 NCBI chr 3:155,820,255...155,913,383
Ensembl chr 3:155,822,963...155,916,194 		JBrowse link
G Kcnb2 potassium voltage-gated channel subfamily B member 2 enables IDA
ISO		 PMID:9305895
PMID:20202934
(PMID:9612272)
PMID:1550672		 RGD PMID:9612272 PMID:9305895 PMID:20202934 PMID:1550672 RGD:737625, RGD:10047337, RGD:728916 NCBI chr 5:3,567,012...4,028,564
Ensembl chr 5:3,569,685...4,028,599 		JBrowse link
G Kcnc1 potassium voltage-gated channel subfamily C member 1 enables IDA
IBA
ISS		 PMID:12954870
GO_REF:0000033
PMID:2023941		 GO_Central PMID:12954870 PMID:2023941 GO_REF:0000033, RGD:10047250, RGD:728931 NCBI chr 1:96,902,953...96,944,744
Ensembl chr 1:96,902,953...96,944,744 		JBrowse link
G Kcnc2 potassium voltage-gated channel subfamily C member 2 enables IDA
IBA		 PMID:10482766
PMID:7643197
PMID:11281123
GO_REF:0000033
PMID:8120636
PMID:1879548
PMID:2367536		 GO_Central PMID:10482766 PMID:7643197 PMID:11281123 PMID:8120636 PMID:1879548 More... GO_REF:0000033, RGD:9685780, RGD:9686052, RGD:10047322, RGD:405650209, RGD:729260, RGD:729382 NCBI chr 7:47,700,035...47,883,979
Ensembl chr 7:47,700,288...47,883,968 		JBrowse link
G Kcnc3 potassium voltage-gated channel subfamily C member 3 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:95,080,960...95,095,165
Ensembl chr 1:95,080,960...95,095,160 		JBrowse link
G Kcnc4 potassium voltage-gated channel subfamily C member 4 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:195,063,967...195,100,244
Ensembl chr 2:195,071,769...195,099,233 		JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 contributes_to
enables		 IMP
ISO
ISS		 (PMID:10400998), (PMID:11299204), (PMID:12522251), (PMID:19646991), (PMID:8900283), (PMID:9354802)
GO_REF:0000024
(PMID:24269949)		 RGD
UniProt		 PMID:8900283 PMID:9354802 PMID:10400998 PMID:11299204 PMID:12522251 More... GO_REF:0000024, RGD:729219 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901 		JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 contributes_to ISO
IDA
IBA		 (PMID:10219239)
GO_REF:0000033		 RGD
GO_Central		 PMID:10219239 PMID:10219239 GO_REF:0000033, RGD:633041 NCBI chr11:31,517,176...31,530,026
Ensembl chr11:31,295,614...31,530,043 		JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 contributes_to IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:154,523,903...154,530,865
Ensembl chr 1:154,523,830...154,532,020 		JBrowse link
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 contributes_to IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:80,243,429...80,251,533
Ensembl chr 9:80,247,379...80,250,979 		JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 contributes_to IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:105,930,398...105,931,013
Ensembl chr  X:105,930,398...105,931,013 		JBrowse link
G Kcnh1 potassium voltage-gated channel subfamily H member 1 enables IDA
ISS
IBA
ISO
IEA		 PMID:27516594
GO_REF:0000024
GO_REF:0000033
(PMID:11943152), (PMID:22732247), (PMID:27005320), (PMID:27325704)
PMID:31490124
(PMID:19671703)
GO_REF:0000117		 UniProt
GO_Central
RGD		 PMID:11943152 PMID:19671703 PMID:22732247 PMID:27005320 PMID:27325704 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000117, RGD:11533419, RGD:405866186 NCBI chr13:103,722,140...104,024,762
Ensembl chr13:103,722,245...104,024,740 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 enables ISO UniProtKB:Q6ZRF8 (PMID:25281747), (PMID:7736582) RGD PMID:7736582 PMID:25281747 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Kcnh5 potassium voltage-gated channel subfamily H member 5 enables IDA
ISS
ISO		 PMID:10594062
GO_REF:0000024
PMID:10882483
(PMID:11943152), (PMID:12135768), (PMID:24133262), (PMID:36928654)		 UniProt
RGD		 PMID:11943152 PMID:12135768 PMID:24133262 PMID:36928654 PMID:10594062 More... GO_REF:0000024, RGD:729094, RGD:727294 NCBI chr 6:93,615,174...93,908,107
Ensembl chr 6:93,624,529...93,908,107 		JBrowse link
G Kcnh8 potassium voltage-gated channel subfamily H member 8 enables IDA
ISO
IEA		 PMID:9714851
(PMID:11897058)
GO_REF:0000107		 RGD
Ensembl		 PMID:11897058 PMID:9714851 GO_REF:0000107, RGD:729210 NCBI chr 9:5,506,044...5,945,828
Ensembl chr 9:5,506,044...5,945,828 		JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 contributes_to
enables		 ISO
IEA
IDA		 (PMID:10400998), (PMID:11299204), (PMID:19646991), (PMID:8900283), (PMID:9354802)
GO_REF:0000107
(PMID:12522251), (PMID:24184248), (PMID:24269949), (PMID:25037568)
PMID:11220365		 RGD
Ensembl		 PMID:8900283 PMID:9354802 PMID:10400998 PMID:11299204 PMID:12522251 More... GO_REF:0000107, RGD:633100 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21087
    transporter activity 1269
      transmembrane transporter activity 1162
        monoatomic ion transmembrane transporter activity 770
          monoatomic ion channel activity 457
            monoatomic cation channel activity 347
              potassium channel activity 131
                voltage-gated potassium channel activity 101
                  delayed rectifier potassium channel activity 24
Path 2
Term Annotations click to browse term
  molecular_function 21087
    transporter activity 1269
      transmembrane transporter activity 1162
        passive transmembrane transporter activity 516
          channel activity 516
            gated channel activity 335
              voltage-gated channel activity 190
                voltage-gated monoatomic ion channel activity 186
                  voltage-gated monoatomic cation channel activity 151
                    voltage-gated potassium channel activity 101
                      delayed rectifier potassium channel activity 24
paths to the root