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ONTOLOGY REPORT - ANNOTATIONS

Term:voltage-gated calcium channel activity
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Accession:GO:0005245 term browser browse the term
Definition:Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
Synonyms:exact_synonym: depolarization-activated voltage gated calcium channel activity;   depolarization-activated voltage-gated calcium channel;   voltage-dependent calcium channel activity;   voltage-gated calcium ion channel activity;   voltage-sensitive calcium channel
 narrow_synonym: dihydropyridine-sensitive calcium channel activity
 broad_synonym: depolarization-activated calcium channel
 alt_id: GO:0010173;   GO:0015270
 xref: Reactome:R-HSA-5577213 "LTCC multimer transports Ca2+ from extracellular region to cytosol";   Reactome:R-HSA-9701055 "TRPA1 tetramer transports Ca2+ from extracellular region to cytosol";   Reactome:R-HSA-9701141 "TRPV1 transports Ca2+ from extracellular region to cytosol";   reactome:R-HSA-265645 "Calcium Influx through Voltage-gated Calcium Channels"


show annotations for term's descendants           Sort by:
voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cachd1 cache domain containing 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:115,411,833...115,637,312
Ensembl chr 5:115,411,071...115,657,505 		JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A enables IDA
IEA
ISO
ISS
TAS		 GO_REF:0000117
MGI:1856209|MGI:1856210|MGI:2181384 (PMID:10611370), (PMID:12151514), (PMID:12827191), (PMID:8632762), (PMID:9614225), (PMID:9857013)
UniProtKB:P54289|UniProtKB:Q02641 (PMID:10753886), (PMID:12451115), (PMID:21883149)
PMID:15980432
GO_REF:0000024		 UniProt
RGD		 PMID:8632762 PMID:9614225 PMID:9857013 PMID:10611370 PMID:10753886 More... GO_REF:0000024 GO_REF:0000117, RGD:634678, RGD:8553366, RGD:634678, RGD:1582495 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225 		JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B enables IMP
ISO
IDA
IEA		 (PMID:1321501), (PMID:25296916)
PMID:10938268
PMID:23699505
PMID:1317580
GO_REF:0000117
MGI:2180187 (PMID:11296258), (PMID:12074836), (PMID:12827191)		 RGD
UniProt		 PMID:1321501 PMID:11296258 PMID:12074836 PMID:12827191 PMID:25296916 More... GO_REF:0000117, RGD:1299351, RGD:8553988, RGD:13792535, RGD:727706 NCBI chr 3:7,380,892...7,546,104
Ensembl chr 3:7,380,922...7,546,091 		JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C enables TAS
ISO
IDA
IEA
IMP		 MGI:2176227|MGI:2389040|MGI:2674114|MGI:2674119|MGI:3047071 (PMID:10973973), (PMID:12881419), (PMID:1385406), (PMID:14609949), (PMID:15504730), (PMID:16251435), (PMID:16267232), (PMID:18586882), (PMID:21216955), (PMID:25368181), (PMID:28119464), (PMID:31430211), (PMID:7635187)
(PMID:9607315)
(PMID:12130699), (PMID:15863612), (PMID:16299511), (PMID:20953164), (PMID:24728418), (PMID:25260352), (PMID:27218670), (PMID:28119464), (PMID:29078335), (PMID:31430211), (PMID:8099908), (PMID:8392192)
(PMID:9087614)
(PMID:12176756)
(PMID:11741969)
(PMID:7737988)
(PMID:17071743)
(PMID:9013606)
PMID:15140941
GO_REF:0000117
MGI:2176227|MGI:2389040|MGI:2674114|MGI:2674119|MGI:3047071 (PMID:12881419), (PMID:1385406), (PMID:14609949), (PMID:15504730), (PMID:16251435), (PMID:16267232), (PMID:7635187)		 RGD
UniProt		 PMID:1385406 PMID:7635187 PMID:7737988 PMID:8099908 PMID:8392192 More... GO_REF:0000117, RGD:625474, RGD:7207149, RGD:1582591, RGD:1580158 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D enables IDA
ISO
IMP
IEA		 (PMID:11160515), (PMID:21131953), (PMID:23913001)
(PMID:18482979)
PMID:17050707
GO_REF:0000117
PMID:21859974		 RGD
UniProt		 PMID:11160515 PMID:18482979 PMID:21131953 PMID:23913001 PMID:11487617 More... GO_REF:0000117, RGD:727563, RGD:407429998, RGD:6767284 NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215 		JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E enables IDA
ISO
IEA		 (PMID:30343943), (PMID:7536609), (PMID:8071363)
PMID:8388125
GO_REF:0000117
MGI:2179732|MGI:2180170|MGI:2451031|MGI:3526823 (PMID:11102459), (PMID:11854466), (PMID:11959138), (PMID:12074836), (PMID:12827191), (PMID:14976402), (PMID:15630454), (PMID:17369816)		 RGD
UniProt		 PMID:7536609 PMID:8071363 PMID:11102459 PMID:11854466 PMID:11959138 More... GO_REF:0000117, RGD:7205480, RGD:1299845 NCBI chr13:66,574,659...67,063,443
Ensembl chr13:66,581,920...66,894,450 		JBrowse link
G Cacna1f calcium voltage-gated channel subunit alpha1 F enables ISO MGI:3609549 (PMID:16155113)
(PMID:12111638), (PMID:15897456), (PMID:27226626)		 RGD PMID:12111638 PMID:15897456 PMID:16155113 PMID:27226626 NCBI chr  X:14,868,096...14,896,413
Ensembl chr  X:14,868,024...14,896,413 		JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G enables ISO
IDA
IEA		 (PMID:11230107)
(PMID:10692398)
(PMID:10648811), (PMID:29878067)
PMID:9495342
GO_REF:0000002		 RGD
InterPro		 PMID:10648811 PMID:10692398 PMID:11230107 PMID:29878067 PMID:9495342 GO_REF:0000002, RGD:68747 NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752 		JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H enables IEA
ISO		 GO_REF:0000002
(PMID:24277868), (PMID:25907736), (PMID:27729216), (PMID:9930755)		 InterPro
RGD		 PMID:9930755 PMID:24277868 PMID:25907736 PMID:27729216 GO_REF:0000002 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376 		JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I enables IEA
ISO		 GO_REF:0000002
(PMID:10749850)
(PMID:33704440)
(PMID:12080115)		 InterPro
RGD		 PMID:10749850 PMID:12080115 PMID:33704440 GO_REF:0000002 NCBI chr 7:111,835,996...111,947,418
Ensembl chr 7:111,836,012...111,944,688 		JBrowse link
G Cacna1s calcium voltage-gated channel subunit alpha1 S enables ISO
IDA
IEA		 (PMID:28012042), (PMID:9852570)
PMID:20101487
GO_REF:0000117
MGI:1856326 (PMID:12954602), (PMID:9929471)		 RGD
UniProt		 PMID:9852570 PMID:9929471 PMID:12954602 PMID:28012042 PMID:20101487 GO_REF:0000117, RGD:407429995 NCBI chr13:47,493,949...47,564,194
Ensembl chr13:47,493,949...47,564,318 		JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 enables
contributes_to		 IMP
IBA
ISO		 GO_REF:0000033
UniProtKB:O00555|UniProtKB:Q02641 (PMID:1309651), (PMID:21883149)
(PMID:11160515), (PMID:17224476)		 GO_Central
RGD		 PMID:1309651 PMID:11160515 PMID:17224476 PMID:21883149 PMID:11604404 GO_REF:0000033, RGD:625474 NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969 		JBrowse link
G Cacna2d2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 enables IDA
ISO
IBA
IEA		 (PMID:11487633)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:11487633 PMID:12606261 GO_REF:0000033 GO_REF:0000107, RGD:632381 NCBI chr 8:108,072,208...108,203,516
Ensembl chr 8:108,072,454...108,203,173 		JBrowse link
G Cacna2d3 calcium voltage-gated channel auxiliary subunit alpha2delta 3 enables IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:12606261 GO_REF:0000033, RGD:632381 NCBI chr16:4,098,439...4,912,498
Ensembl chr16:4,098,445...4,912,351 		JBrowse link
G Cacna2d4 calcium voltage-gated channel auxiliary subunit alpha2delta 4 enables ISO
IBA		 (PMID:12181424)
GO_REF:0000033		 RGD
GO_Central		 PMID:12181424 GO_REF:0000033 NCBI chr 4:152,408,588...152,521,478
Ensembl chr 4:152,408,657...152,521,268 		JBrowse link
G Cacnb1 calcium voltage-gated channel auxiliary subunit beta 1 contributes_to
enables		 IDA
ISO
IEA		 MGI:2181804 (PMID:1370480), (PMID:8943043), (PMID:9929471)
GO_REF:0000002		 RGD
InterPro		 PMID:1370480 PMID:8943043 PMID:9929471 PMID:16049183 PMID:16554304 GO_REF:0000002, RGD:1582495, RGD:1582591 NCBI chr10:82,998,182...83,018,838
Ensembl chr10:82,998,182...83,018,694 		JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 enables
contributes_to		 TAS
ISO
IEA
IDA		 (PMID:1309651)
GO_REF:0000002		 RGD
InterPro		 PMID:1309651 PMID:1370480 PMID:16049183 GO_REF:0000002, RGD:632405, RGD:1582495 NCBI chr17:77,564,630...77,910,000
Ensembl chr17:77,564,460...77,909,106 		JBrowse link
G Cacnb2_v1 calcium voltage-gated channel auxiliary subunit beta 2, variant 1 contributes_to IDA RGD PMID:16049183 RGD:1582495
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 enables
contributes_to		 IMP
IEA
ISO
TAS		 GO_REF:0000107
GO_REF:0000002
(PMID:11160515)		 Ensembl
InterPro
RGD		 PMID:11160515 PMID:14559910 PMID:7685340 GO_REF:0000002 GO_REF:0000107, RGD:1358466, RGD:634680 NCBI chr 7:129,784,799...129,797,074
Ensembl chr 7:129,783,674...129,797,074 		JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 enables
contributes_to		 IMP
ISO
IEA		 MGI:1856936 (PMID:12151514), (PMID:9705268)
GO_REF:0000002
(PMID:16525042)		 RGD
InterPro		 PMID:9705268 PMID:12151514 PMID:16525042 PMID:12821675 GO_REF:0000002, RGD:737839 NCBI chr 3:36,906,771...37,169,165
Ensembl chr 3:36,910,427...37,168,944 		JBrowse link
G Cacng1 calcium voltage-gated channel auxiliary subunit gamma 1 enables TAS
ISO
IEA		 MGI:2180153 (PMID:10799530), (PMID:15504904)
GO_REF:0000107		 RGD
Ensembl		 PMID:10799530 PMID:15504904 PMID:11738816 GO_REF:0000107, RGD:70681 NCBI chr10:92,652,924...92,665,612
Ensembl chr10:92,652,614...92,665,783 		JBrowse link
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 enables TAS
ISO
IBA		 MGI:1856548 (PMID:12151514)
GO_REF:0000033		 RGD
GO_Central		 PMID:12151514 PMID:11738816 GO_REF:0000033, RGD:70681 NCBI chr 7:109,572,838...109,698,516
Ensembl chr 7:109,574,459...109,697,227 		JBrowse link
G Cacng3 calcium voltage-gated channel auxiliary subunit gamma 3 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:177,201,361...177,297,019
Ensembl chr 1:177,201,288...177,297,024 		JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:92,683,778...92,745,842
Ensembl chr10:92,683,761...92,746,126 		JBrowse link
G Cacng5 calcium voltage-gated channel auxiliary subunit gamma 5 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:92,827,441...92,869,632
Ensembl chr10:92,829,196...92,869,614 		JBrowse link
G Cacng7 calcium voltage-gated channel auxiliary subunit gamma 7 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:65,800,059...65,831,246
Ensembl chr 1:65,800,355...65,831,006 		JBrowse link
G Cacng8 calcium voltage-gated channel auxiliary subunit gamma 8 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:65,755,334...65,775,567
Ensembl chr 1:65,755,334...65,779,089 		JBrowse link
G Calhm1 calcium homeostasis modulator 1 enables ISO (MGI:5432299|PMID:22711817)
(PMID:22711817)		 RGD PMID:22711817 MGI:5432299 NCBI chr 1:246,030,269...246,032,988
Ensembl chr 1:246,030,269...246,032,988 		JBrowse link
G Catsper1 cation channel, sperm associated 1 enables IBA
ISO		 GO_REF:0000033
(PMID:14657352)
MGI:2387461 (PMID:17478420)		 GO_Central
RGD		 PMID:14657352 PMID:17478420 GO_REF:0000033 NCBI chr 1:202,643,009...202,652,059
Ensembl chr 1:202,643,038...202,651,824 		JBrowse link
G Catsper2 cation channel, sperm associated 2 enables ISO
ISS		 (PMID:21412338)
(PMID:21412339)
GO_REF:0000024		 RGD
UniProt		 PMID:21412338 PMID:21412339 GO_REF:0000024 NCBI chr 3:108,368,654...108,389,380
Ensembl chr 3:108,368,668...108,388,050 		JBrowse link
G Catsper3 cation channel, sperm associated 3 enables IBA
ISO		 GO_REF:0000033
MGI:3694352 (PMID:17227845)		 GO_Central
RGD		 PMID:17227845 GO_REF:0000033 NCBI chr17:8,810,122...8,840,881
Ensembl chr17:8,815,561...8,840,864 		JBrowse link
G Catsper4 cation channel, sperm associated 4 enables IBA
ISO		 GO_REF:0000033
MGI:3694354 (PMID:17227845)		 GO_Central
RGD		 PMID:17227845 GO_REF:0000033 NCBI chr 5:146,427,682...146,447,346
Ensembl chr 5:146,427,683...146,446,942 		JBrowse link
G Grm7 glutamate metabotropic receptor 7 enables ISO (MGI:3690146|PMID:12065412)
(PMID:12065412)		 RGD PMID:12065412 MGI:3690146 NCBI chr 4:143,730,862...144,613,230
Ensembl chr 4:143,731,259...144,612,344 		JBrowse link
G Itgav integrin subunit alpha V enables ISO (PMID:18395422) RGD PMID:18395422 NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639 		JBrowse link
G Ncs1 neuronal calcium sensor 1 enables IMP PMID:17502602 UniProt PMID:17502602 RGD:8553610 NCBI chr 3:14,523,220...14,568,829
Ensembl chr 3:14,523,220...14,568,829 		JBrowse link
G Oprm1 opioid receptor, mu 1 enables IMP PMID:1846076 UniProt PMID:1846076 RGD:8656003 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel enables ISO
IBA		 (PMID:11252306), (PMID:15692563)
GO_REF:0000033		 RGD
GO_Central		 PMID:11252306 PMID:15692563 GO_REF:0000033 NCBI chr14:5,237,135...5,280,455
Ensembl chr14:5,237,135...5,280,825 		JBrowse link
G Ryr1 ryanodine receptor 1 enables ISS
ISO		 GO_REF:0000024
(MGI:3764002|PMID:18003898), (PMID:12954602)		 UniProt
RGD		 PMID:12954602 PMID:18003898 GO_REF:0000024 MGI:3764002 NCBI chr 1:84,292,578...84,423,824
Ensembl chr 1:84,292,578...84,423,812 		JBrowse link
G Tmc1 transmembrane channel-like 1 enables IBA
ISO		 GO_REF:0000033
MGI:2151017|MGI:5427097 (PMID:23871232)		 GO_Central
RGD		 PMID:23871232 GO_REF:0000033 NCBI chr 1:218,275,249...218,446,013
Ensembl chr 1:218,276,417...218,445,955 		JBrowse link
G Tmc2 transmembrane channel-like 2 enables IBA
ISO		 GO_REF:0000033
MGI:2151016|MGI:5427099 (PMID:23871232)		 GO_Central
RGD		 PMID:23871232 GO_REF:0000033 NCBI chr 3:117,396,378...117,464,336
Ensembl chr 3:117,396,378...117,464,336 		JBrowse link
G Tpcn2 two pore segment channel 2 enables
NOT|enables		 ISO (MGI:5285159|PMID:20495006)
(PMID:20495006)
(PMID:23063126)		 RGD PMID:20495006 PMID:23063126 MGI:5285159 NCBI chr 1:200,416,538...200,446,252
Ensembl chr 1:200,416,540...200,446,236 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 IDA RGD PMID:14712238 RGD:1303969 NCBI chr 5:4,379,862...4,434,133
Ensembl chr 5:4,379,999...4,433,570 		JBrowse link
high voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1a calcium voltage-gated channel subunit alpha1 A enables IDA
ISO
IEA
IBA		 MGI:102522|MGI:1856209|MGI:1856210|MGI:1856211|MGI:2180190|MGI:2181384 (PMID:10908603), (PMID:11344116), (PMID:11718712), (PMID:11756409), (PMID:12040045), (PMID:12065603), (PMID:12401561), (PMID:12624181), (PMID:15548652), (PMID:9742139)
(PMID:21883149), (PMID:23376566), (PMID:24836863), (PMID:26716990)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:9742139 PMID:10908603 PMID:11344116 PMID:11718712 PMID:11756409 More... GO_REF:0000033 GO_REF:0000107, RGD:7205477, RGD:7205480 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225 		JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B enables IDA
ISO
IBA		 (PMID:23648579)
GO_REF:0000033
(PMID:23376566)		 RGD
GO_Central		 PMID:23376566 PMID:23648579 PMID:18701069 GO_REF:0000033, RGD:7205441 NCBI chr 3:7,380,892...7,546,104
Ensembl chr 3:7,380,922...7,546,091 		JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C enables IDA
IBA
ISO		 GO_REF:0000033
(PMID:15454078)		 GO_Central
RGD		 PMID:15454078 PMID:17068255 GO_REF:0000033, RGD:7205477 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D enables
contributes_to		 IDA
ISO
IBA
IEA		 (PMID:12900400)
GO_REF:0000033
GO_REF:0000107
(PMID:1309651)		 RGD
GO_Central
Ensembl		 PMID:1309651 PMID:12900400 PMID:18322004 GO_REF:0000033 GO_REF:0000107, RGD:7207845 NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215 		JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:66,574,659...67,063,443
Ensembl chr13:66,581,920...66,894,450 		JBrowse link
G Cacna1f calcium voltage-gated channel subunit alpha1 F enables IC
IBA
ISO		 GO_REF:0000033
(PMID:27226626)		 GO_Central
RGD		 PMID:27226626 PMID:11526344 GO_REF:0000033, RGD:632484 NCBI chr  X:14,868,096...14,896,413
Ensembl chr  X:14,868,024...14,896,413 		JBrowse link
G Cacna1s calcium voltage-gated channel subunit alpha1 S enables IDA
IBA
ISO
IEA		 GO_REF:0000033
(PMID:9852570)
GO_REF:0000107		 GO_Central
RGD
Ensembl		 PMID:9852570 PMID:7479909 GO_REF:0000033 GO_REF:0000107, RGD:634679 NCBI chr13:47,493,949...47,564,194
Ensembl chr13:47,493,949...47,564,318 		JBrowse link
G Cacnb1 calcium voltage-gated channel auxiliary subunit beta 1 enables IBA
ISO		 GO_REF:0000033
MGI:109482 (PMID:11756409)		 GO_Central
RGD		 PMID:11756409 GO_REF:0000033 NCBI chr10:82,998,182...83,018,838
Ensembl chr10:82,998,182...83,018,694 		JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 contributes_to
enables		 ISO
IBA
IEA		 (PMID:1309651)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:1309651 GO_REF:0000033 GO_REF:0000107 NCBI chr17:77,564,630...77,910,000
Ensembl chr17:77,564,460...77,909,106 		JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 contributes_to
enables		 ISO
IBA		 (PMID:11880487)
GO_REF:0000033		 RGD
GO_Central		 PMID:11880487 GO_REF:0000033 NCBI chr 3:36,906,771...37,169,165
Ensembl chr 3:36,910,427...37,168,944 		JBrowse link
low voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1e calcium voltage-gated channel subunit alpha1 E TAS RGD PMID:9405717 RGD:69790 NCBI chr13:66,574,659...67,063,443
Ensembl chr13:66,581,920...66,894,450 		JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G enables IDA
ISO
IBA
IEA		 (PMID:16690884)
GO_REF:0000033
GO_REF:0000107
(PMID:21084288), (PMID:26456284), (PMID:26715324)		 RGD
GO_Central
Ensembl		 PMID:16690884 PMID:21084288 PMID:26456284 PMID:26715324 PMID:18759855 More... GO_REF:0000033 GO_REF:0000107, RGD:2308879, RGD:7207257, RGD:7175320 NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752 		JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H enables IDA
IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:21084288)		 GO_Central
Ensembl
RGD		 PMID:21084288 PMID:11073957 PMID:16935432 GO_REF:0000033 GO_REF:0000107, RGD:68748, RGD:7207257 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376 		JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I enables IDA
IBA		 GO_REF:0000033
PMID:10066244		 GO_Central
RGD		 PMID:18760992 PMID:10066244 PMID:16935432 GO_REF:0000033, RGD:7175320, RGD:68867, RGD:7207257 NCBI chr 7:111,835,996...111,947,418
Ensembl chr 7:111,836,012...111,944,688 		JBrowse link
voltage-gated calcium channel activity involved in AV node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C enables ISO
ISS		 (PMID:26253506)
GO_REF:0000024		 RGD
BHF-UCL		 PMID:26253506 GO_REF:0000024 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G enables ISS
ISO		 GO_REF:0000024
(MGI:3714901|PMID:16690884)		 BHF-UCL
RGD		 PMID:16690884 GO_REF:0000024 MGI:3714901 NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752 		JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 contributes_to
enables		 ISO
IEA
ISS		 (PMID:17224476)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
BHF-UCL		 PMID:17224476 GO_REF:0000024 GO_REF:0000107 NCBI chr17:77,564,630...77,910,000
Ensembl chr17:77,564,460...77,909,106 		JBrowse link
voltage-gated calcium channel activity involved in bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 contributes_to
enables		 ISO
IEA		 (PMID:21383000)
GO_REF:0000107		 RGD
Ensembl		 PMID:21383000 GO_REF:0000107 NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969 		JBrowse link
voltage-gated calcium channel activity involved in cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C contributes_to
enables		 ISO
ISS		 (PMID:17224476)
(PMID:32109384)
GO_REF:0000024
(PMID:15454078)		 RGD
BHF-UCL		 PMID:15454078 PMID:17224476 PMID:32109384 GO_REF:0000024 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D enables IC PMID:21859974 BHF-UCL PMID:21859974 RGD:6767284 NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215 		JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 contributes_to ISO
ISS		 (PMID:17224476)
GO_REF:0000024		 RGD
BHF-UCL		 PMID:17224476 GO_REF:0000024 NCBI chr17:77,564,630...77,910,000
Ensembl chr17:77,564,460...77,909,106 		JBrowse link
voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1a calcium voltage-gated channel subunit alpha1 A enables ISO (PMID:25741235) RGD PMID:25741235 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225 		JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B enables IDA
EXP		 PMID:7832825 SynGO PMID:7832825 PMID:7832825 RGD:13792530, RGD:13792530 NCBI chr 3:7,380,892...7,546,104
Ensembl chr 3:7,380,922...7,546,091 		JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D enables ISO (PMID:10929716) RGD PMID:10929716 NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215 		JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E enables EXP
IDA		 PMID:19193890 SynGO PMID:19193890 PMID:19193890 RGD:13792544, RGD:13792544 NCBI chr13:66,574,659...67,063,443
Ensembl chr13:66,581,920...66,894,450 		JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 enables IEA
ISO		 GO_REF:0000107
(PMID:11980879)		 Ensembl
RGD		 PMID:11980879 GO_REF:0000107 NCBI chr17:77,564,630...77,910,000
Ensembl chr17:77,564,460...77,909,106 		JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 enables ISO (PMID:10322048) RGD PMID:10322048 NCBI chr 3:36,906,771...37,169,165
Ensembl chr 3:36,910,427...37,168,944 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B enables IDA
EXP		 PMID:17067296 SynGO PMID:17067296 PMID:17067296 RGD:13702319, RGD:13702319 NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Rimbp2 RIMS binding protein 2 enables ISO (PMID:26402606) RGD PMID:26402606 NCBI chr12:27,747,615...27,946,256
Ensembl chr12:27,747,980...27,956,763 		JBrowse link
G Tspoap1 TSPO associated protein 1 enables IEA
ISO		 GO_REF:0000107
(PMID:26402606)		 Ensembl
RGD		 PMID:26402606 GO_REF:0000107 NCBI chr10:72,554,220...72,586,402
Ensembl chr10:72,560,980...72,586,412 		JBrowse link
voltage-gated calcium channel activity involved SA node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1d calcium voltage-gated channel subunit alpha1 D enables ISO
IEA		 (PMID:21131953)
MGI:2180141 (PMID:15932895)
GO_REF:0000107		 RGD
Ensembl		 PMID:15932895 PMID:21131953 GO_REF:0000107 NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215 		JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G enables ISS
ISO		 GO_REF:0000024
(MGI:3714901|PMID:16690884)		 BHF-UCL
RGD		 PMID:16690884 GO_REF:0000024 MGI:3714901 NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20732
    transporter activity 1234
      transmembrane transporter activity 1136
        monoatomic ion transmembrane transporter activity 757
          monoatomic ion channel activity 445
            monoatomic cation channel activity 336
              calcium channel activity 127
                voltage-gated calcium channel activity 45
                  high voltage-gated calcium channel activity 10
                  intermediate voltage-gated calcium channel activity 0
                  light-activated voltage-gated calcium channel activity 0
                  low voltage-gated calcium channel activity 4
                  voltage-gated calcium channel activity involved in cardiac muscle cell action potential + 5
                  voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels 0
                  voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels + 9
Path 2
Term Annotations click to browse term
  molecular_function 20732
    transporter activity 1234
      transmembrane transporter activity 1136
        passive transmembrane transporter activity 503
          channel activity 503
            gated channel activity 331
              voltage-gated channel activity 189
                voltage-gated monoatomic ion channel activity 185
                  voltage-gated monoatomic cation channel activity 151
                    voltage-gated calcium channel activity 45
                      high voltage-gated calcium channel activity 10
                      intermediate voltage-gated calcium channel activity 0
                      light-activated voltage-gated calcium channel activity 0
                      low voltage-gated calcium channel activity 4
                      voltage-gated calcium channel activity involved in cardiac muscle cell action potential + 5
                      voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels 0
                      voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels + 9
paths to the root