intracellular sodium-activated potassium channel activity - Ontology Report

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Term:	intracellular sodium-activated potassium channel activity	go back to main search page
Accession:	GO:0005228	browse the term
Definition:	Enables the transmembrane transfer of potassium by a channel that opens in response to stimulus by a sodium ion or ions. Transport by a channel involves facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. Sodium activated potassium channels have distinctive properties, including a large single channel conductance, subconductance states, and a block of single channel currents at positive potentials, similar to inward rectification.

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Genes (2)

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Kcnt1

potassium sodium-activated channel subfamily T member 1

enables

PMID:14684870
(PMID:37494189)
GO_REF:0000033

GO_REF:0000033, RGD:1299633

NCBI chr 3:29,081,071...29,136,902
Ensembl chr 3:8,682,113...8,736,667

potassium sodium-activated channel subfamily T member 2

enables

(PMID:14684870)
GO_REF:0000107
GO_REF:0000033

GO_REF:0000033 GO_REF:0000107, RGD:1299633

NCBI chr13:54,214,831...54,609,889
Ensembl chr13:51,664,686...52,056,987

Term paths to the root

Path 1
Term	Annotations
molecular_function	21100
transporter activity	1274
transmembrane transporter activity	1165
monoatomic ion transmembrane transporter activity	771
monoatomic cation transmembrane transporter activity	652
monoatomic cation channel activity	347
ligand-gated monoatomic cation channel activity	129
intracellular sodium-activated potassium channel activity	2
Path 2
Term	Annotations
molecular_function	21100
transporter activity	1274
transmembrane transporter activity	1165
passive transmembrane transporter activity	516
channel activity	516
gated channel activity	335
ligand-gated channel activity	190
ligand-gated monoatomic ion channel activity	185
ligand-gated monoatomic cation channel activity	129
intracellular sodium-activated potassium channel activity	2

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