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ONTOLOGY REPORT - ANNOTATIONS

Term:phosphoglycerate dehydrogenase activity
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Accession:GO:0004617 term browser browse the term
Definition:Catalysis of the reaction: 3-phosphoglycerate + NAD+ = 3-phosphohydroxypyruvate + NADH + H+.
Synonyms:related_synonym: 3-phospho-D-glycerate:NAD+ 2-oxidoreductase activity;   3-phosphoglycerate dehydrogenase activity;   3-phosphoglycerate:NAD+ 2-oxidoreductase activity;   3-phosphoglyceric acid dehydrogenase activity;   3PHP reductase activity;   D- and L-HGA;   D-3-phosphoglycerate dehydrogenase activity;   D-3-phosphoglycerate:NAD+ oxidoreductase activity;   PGDH activity;   SerA;   SerA 3PG dehydrogenase activity;   alpha-KG reductase activity;   alpha-phosphoglycerate dehydrogenase activity;   alphaKG reductase activity;   glycerate 3-phosphate dehydrogenase activity;   glycerate-1,3-phosphate dehydrogenase activity;   phosphoglycerate oxidoreductase activity;   phosphoglyceric acid dehydrogenase activity
 xref: EC:1.1.1.95;   MetaCyc:PGLYCDEHYDROG-RXN;   RHEA:12641;   Reactome:R-HSA-977348 "PHGDH tetramer dehydrogenates 3PG"


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phosphoglycerate dehydrogenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Phgdh phosphoglycerate dehydrogenase enables IDA
IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central
RGD		 PMID:9163325 GO_REF:0000002 GO_REF:0000033, RGD:61693 NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944 		JBrowse link
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  molecular_function 20634
    catalytic activity 6032
      oxidoreductase activity 854
        oxidoreductase activity, acting on CH-OH group of donors 161
          oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 152
            phosphoglycerate dehydrogenase activity 1
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