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ONTOLOGY REPORT - ANNOTATIONS

Term:endonuclease activity
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Accession:GO:0004519 term browser browse the term
Definition:Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
Synonyms:xref: reactome:R-HSA-5358512 "MLH1:PMS2 makes single strand incision near insertion/deletion loop of 2 bases or more";   reactome:R-HSA-5358518 "MLH1:PMS2 makes single strand incision near 1-2 base mismatch";   reactome:R-HSA-5690990 "5'- incision of DNA by ERCC1:ERCC4 in GG-NER";   reactome:R-HSA-5693533 "DCLRE1C (ARTEMIS) processes DNA DSB ends";   reactome:R-HSA-72180 "Cleavage of mRNA at the 3'-end"


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endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGO2 argonaute RISC catalytic component 2 enables IEA UniProt GO_REF:0000043 NCBI chr 8:137,192,037...137,308,059
Ensembl chr 8:140,287,647...140,361,125 		JBrowse link
G AGO3 argonaute RISC catalytic component 3 enables IEA UniProt GO_REF:0000043 NCBI chr 1:35,196,371...35,322,220
Ensembl chr 1:36,372,221...36,497,190 		JBrowse link
G ALKBH2 alkB homolog 2, alpha-ketoglutarate dependent dioxygenase NOT|enables ISO (PMID:16174769) MGI PMID:16174769 NCBI chr12:106,664,678...106,670,558
Ensembl chr12:110,058,507...110,063,946 		JBrowse link
G ALKBH3 alkB homolog 3, alpha-ketoglutarate dependent dioxygenase NOT|enables ISO (PMID:16174769) MGI PMID:16174769 NCBI chr11:43,841,083...43,880,608
Ensembl chr11:44,336,655...44,376,057 		JBrowse link
G ANG angiogenin enables IEA UniProt GO_REF:0000043 NCBI chr14:1,548,693...1,558,528
Ensembl chr14:19,614,950...19,615,393 		JBrowse link
G ANKLE1 ankyrin repeat and LEM domain containing 1 enables IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr19:16,769,670...16,775,114
Ensembl chr19:17,744,570...17,750,070 		JBrowse link
G ANKZF1 ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1 enables IEA UniProt GO_REF:0000043 NCBI chr2B:106,487,377...106,494,258
Ensembl chr2B:225,078,322...225,085,205 		JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 enables IEA InterPro
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 NCBI chr14:1,329,745...1,332,315
Ensembl chr14:19,381,911...19,384,542 		JBrowse link
G APEX2 apurinic/apyrimidinic endodeoxyribonuclease 2 enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr  X:47,210,552...47,218,320
Ensembl chr  X:55,442,599...55,450,402 		JBrowse link
G BIVM basic, immunoglobulin-like variable motif containing enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr13:83,959,365...84,002,223
Ensembl chr13:103,096,344...103,174,182 		JBrowse link
G DCLRE1C DNA cross-link repair 1C enables IEA UniProt GO_REF:0000043 NCBI chr10:14,901,335...14,956,947
Ensembl chr10:15,236,558...15,269,043 		JBrowse link
G DICER1 dicer 1, ribonuclease III enables IEA UniProt GO_REF:0000043 NCBI chr14:75,709,029...75,780,779
Ensembl chr14:95,036,385...95,107,940 		JBrowse link
G DIS3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr13:53,982,914...54,011,076
Ensembl chr13:72,760,610...72,787,325 		JBrowse link
G DNASE1 deoxyribonuclease 1 enables IEA UniProt GO_REF:0000043 NCBI chr16:2,532,281...2,583,408
Ensembl chr16:3,708,189...3,758,615 		JBrowse link
G DNASE1L1 deoxyribonuclease 1 like 1 enables IEA UniProt GO_REF:0000043 NCBI chr  X:143,842,920...143,851,795
Ensembl chr  X:153,712,054...153,725,868 		JBrowse link
G DNASE1L2 deoxyribonuclease 1 like 2 enables IEA UniProt GO_REF:0000043 NCBI chr16:1,093,669...1,096,123
Ensembl chr16:2,336,768...2,338,391 		JBrowse link
G DNASE1L3 deoxyribonuclease 1L3 enables IEA UniProt
Ensembl		 GO_REF:0000043 GO_REF:0000107 NCBI chr 3:58,127,491...58,146,177
Ensembl chr 3:59,542,243...59,560,363 		JBrowse link
G DNASE2 deoxyribonuclease 2, lysosomal enables IEA UniProt GO_REF:0000043 NCBI chr19:12,436,898...12,443,530
Ensembl chr19:13,180,073...13,185,650 		JBrowse link
G DNASE2B deoxyribonuclease 2 beta enables IEA UniProt GO_REF:0000043 NCBI chr 1:116,946,513...116,963,483
Ensembl chr 1:85,807,300...85,824,257 		JBrowse link
G DROSHA drosha ribonuclease III enables IEA UniProt GO_REF:0000043 NCBI chr 5:78,813,923...78,945,149
Ensembl chr 5:84,194,546...84,322,310 		JBrowse link
G ELAC1 elaC ribonuclease Z 1 enables IEA UniProt GO_REF:0000043 NCBI chr18:44,339,868...44,359,150
Ensembl chr18:47,692,305...47,706,019 		JBrowse link
G ELAC2 elaC ribonuclease Z 2 enables IEA UniProt GO_REF:0000043 NCBI chr17:38,631,454...38,657,855
Ensembl chr17:43,331,453...43,357,241 		JBrowse link
G EME1 essential meiotic structure-specific endonuclease 1 enables IEA UniProt GO_REF:0000043 NCBI chr17:44,467,537...44,475,883
Ensembl chr17:49,341,791...49,349,959 		JBrowse link
G EME2 essential meiotic structure-specific endonuclease subunit 2 enables IEA UniProt GO_REF:0000043 NCBI chr16:395,571...403,233
Ensembl chr16:1,825,622...1,829,557 		JBrowse link
G ENDOG endonuclease G enables IEA UniProt
TreeGrafter		 GO_REF:0000043 GO_REF:0000104 GO_REF:0000118 NCBI chr 9:99,941,856...99,945,957 JBrowse link
G ENDOU endonuclease, poly(U) specific enables IEA UniProt GO_REF:0000043 NCBI chr12:41,003,037...41,024,127
Ensembl chr12:41,882,483...41,897,119 		JBrowse link
G ENDOV endonuclease V enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr17:74,843,661...74,865,960
Ensembl chr17:80,576,450...80,591,856 		JBrowse link
G ERCC4 ERCC excision repair 4, endonuclease catalytic subunit enables IEA UniProt GO_REF:0000043 NCBI chr16:12,848,334...12,880,480
Ensembl chr16:14,272,417...14,304,496 		JBrowse link
G ERCC5 ERCC excision repair 5, endonuclease enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr13:84,005,950...84,036,710
Ensembl chr13:103,096,344...103,174,182 		JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 enables IEA Ensembl GO_REF:0000107 NCBI chr17:58,132,889...58,224,012
Ensembl chr17:63,226,949...63,317,825 		JBrowse link
G ERN2 endoplasmic reticulum to nucleus signaling 2 enables IEA Ensembl GO_REF:0000107 NCBI chr16:14,397,697...14,420,618
Ensembl chr16:23,940,716...23,963,894 		JBrowse link
G EXO1 exonuclease 1 enables IEA UniProt GO_REF:0000043 NCBI chr 1:217,410,175...217,451,982
Ensembl chr 1:222,389,684...222,431,556 		JBrowse link
G EXOG exo/endonuclease G enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:38,392,968...38,422,990
Ensembl chr 3:38,674,970...38,703,750 		JBrowse link
G FEN1 flap structure-specific endonuclease 1 enables IEA UniProt GO_REF:0000043 NCBI chr11:57,092,270...57,096,828
Ensembl chr11:60,455,474...60,456,616 		JBrowse link
G LAS1L LAS1 like ribosome biogenesis factor enables IEA InterPro GO_REF:0000002 NCBI chr  X:54,628,539...54,650,756
Ensembl chr  X:64,703,731...64,727,169 		JBrowse link
G LOC100981889 non-secretory ribonuclease enables IEA UniProt GO_REF:0000043 NCBI chr14:1,759,482...1,760,873
Ensembl chr14:19,841,364...19,841,849 		JBrowse link
G LOC100986203 histone-lysine N-methyltransferase SETMAR enables IEA Ensembl GO_REF:0000107 NCBI chr 3:4,256,539...4,271,593
Ensembl chr 3:4,357,890...4,371,791 		JBrowse link
G MRE11 MRE11 homolog, double strand break repair nuclease enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr11:89,418,537...89,500,705
Ensembl chr11:92,918,549...92,985,966 		JBrowse link
G MUS81 MUS81 structure-specific endonuclease subunit enables IEA UniProt
Ensembl		 GO_REF:0000043 GO_REF:0000107 NCBI chr11:61,220,699...61,226,747
Ensembl chr11:64,549,840...64,555,875 		JBrowse link
G N4BP2 NEDD4 binding protein 2 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:34,380,215...34,482,797
Ensembl chr 4:40,253,199...40,336,040 		JBrowse link
G NOB1 NIN1 (RPN12) binding protein 1 homolog enables IEA UniProt GO_REF:0000043 NCBI chr16:50,122,905...50,135,096
Ensembl chr16:69,506,425...69,517,932 		JBrowse link
G RAG1 recombination activating 1 enables IEA UniProt
Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107 NCBI chr11:36,483,697...36,546,242
Ensembl chr11:36,412,420...36,422,904 		JBrowse link
G RBBP8 RB binding protein 8, endonuclease enables IEA UniProt GO_REF:0000043 NCBI chr18:16,181,652...16,274,597
Ensembl chr18:19,811,989...19,903,522 		JBrowse link
G REXO4 REX4 homolog, 3'-5' exonuclease enables IEA Ensembl GO_REF:0000107 NCBI chr 9:104,528,838...104,540,813
Ensembl chr 9:133,140,392...133,152,413 		JBrowse link
G RNASE1 ribonuclease A family member 1, pancreatic enables IEA UniProt GO_REF:0000043 NCBI chr14:1,663,595...1,665,121
Ensembl chr14:19,720,127...19,720,597 		JBrowse link
G RNASE4 ribonuclease A family member 4 enables IEA UniProt GO_REF:0000043 NCBI chr14:1,548,729...1,564,819
Ensembl chr14:19,620,758...19,621,201 		JBrowse link
G RNASE6 ribonuclease A family member 6 enables IEA UniProt GO_REF:0000043 NCBI chr14:1,642,819...1,644,582
Ensembl chr14:19,700,536...19,700,988 		JBrowse link
G RNASE7 ribonuclease A family member 7 enables IEA UniProt GO_REF:0000043 NCBI chr14:1,857,213...1,858,781
Ensembl chr14:19,939,884...19,940,354 		JBrowse link
G RNASE8 ribonuclease A family member 8 enables IEA UniProt GO_REF:0000043 NCBI chr14:1,872,595...1,873,331
Ensembl chr14:19,954,680...19,955,147 		JBrowse link
G RNASEH1 ribonuclease H1 enables IEA UniProt GO_REF:0000043 NCBI chr2A:3,550,303...3,578,161
Ensembl chr2A:3,482,772...3,496,978 		JBrowse link
G RNASEH2A ribonuclease H2 subunit A enables IEA UniProt GO_REF:0000043 NCBI chr19:12,363,721...12,375,316
Ensembl chr19:13,112,242...13,119,514 		JBrowse link
G SLC25A16 solute carrier family 25 member 16 enables IEA UniProt GO_REF:0000043 NCBI chr10:64,898,024...64,956,541
Ensembl chr10:67,506,006...67,549,308
Ensembl chr10:67,506,006...67,549,308 		JBrowse link
G SLX1A SLX1 homolog A, structure-specific endonuclease subunit enables IEA UniProt GO_REF:0000043
G SMG6 SMG6 nonsense mediated mRNA decay factor enables IEA UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr17:2,050,825...2,294,892
Ensembl chr17:1,937,630...2,179,535 		JBrowse link
G SND1 staphylococcal nuclease and tudor domain containing 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 7:119,647,536...120,084,110
Ensembl chr 7:132,302,235...132,738,223 		JBrowse link
G TSEN2 tRNA splicing endonuclease subunit 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 3:12,410,885...12,463,932
Ensembl chr 3:12,759,375...12,800,201 		JBrowse link
G YBEY ybeY metalloendoribonuclease enables IEA UniProt GO_REF:0000043 NCBI chr21:32,628,599...32,638,914
Ensembl chr21:45,879,824...45,888,717 		JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A enables IEA UniProt GO_REF:0000043 NCBI chr 1:36,743,341...36,753,261
Ensembl chr 1:38,093,917...38,103,556 		JBrowse link
G ZC3H12B zinc finger CCCH-type containing 12B enables IEA UniProt GO_REF:0000043 NCBI chr  X:54,162,659...54,623,859
Ensembl chr  X:64,563,916...64,699,055 		JBrowse link
G ZC3H12C zinc finger CCCH-type containing 12C enables IEA UniProt GO_REF:0000043 NCBI chr11:104,975,798...105,054,382
Ensembl chr11:108,859,581...108,899,858 		JBrowse link
G ZC3H12D zinc finger CCCH-type containing 12D enables IEA UniProt GO_REF:0000043 NCBI chr 6:147,266,039...147,304,289
Ensembl chr 6:151,974,485...151,999,898 		JBrowse link
G ZRANB3 zinc finger RANBP2-type containing 3 enables IEA InterPro GO_REF:0000002 NCBI chr2B:24,331,731...24,665,652
Ensembl chr2B:139,234,909...139,577,193 		JBrowse link
3' overhang single-stranded DNA endodeoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASTE1 asteroid homolog 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 3:128,098,219...128,111,196
Ensembl chr 3:135,421,044...135,432,284 		JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit contributes_to IEA Ensembl GO_REF:0000107 NCBI chr19:42,356,039...42,427,754
Ensembl chr19:50,951,674...50,968,430 		JBrowse link
G ERCC4 ERCC excision repair 4, endonuclease catalytic subunit contributes_to IEA Ensembl GO_REF:0000107 NCBI chr16:12,848,334...12,880,480
Ensembl chr16:14,272,417...14,304,496 		JBrowse link
G XRCC1 X-ray repair cross complementing 1 contributes_to IEA Ensembl GO_REF:0000107 NCBI chr19:40,485,052...40,522,188
Ensembl chr19:49,094,014...49,125,520 		JBrowse link
G XRCC4 X-ray repair cross complementing 4 contributes_to ISO (PMID:14690602) BHF-UCL PMID:14690602 NCBI chr 5:31,927,463...32,202,394
Ensembl chr 5:32,246,320...32,521,490 		JBrowse link
3'-flap endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MUS81 MUS81 structure-specific endonuclease subunit enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:61,220,699...61,226,747
Ensembl chr11:64,549,840...64,555,875 		JBrowse link
3'-tRNA processing endoribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ELAC1 elaC ribonuclease Z 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr18:44,339,868...44,359,150
Ensembl chr18:47,692,305...47,706,019 		JBrowse link
G ELAC2 elaC ribonuclease Z 2 enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000118 NCBI chr17:38,631,454...38,657,855
Ensembl chr17:43,331,453...43,357,241 		JBrowse link
5'-flap endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EXO1 exonuclease 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 1:217,410,175...217,451,982
Ensembl chr 1:222,389,684...222,431,556 		JBrowse link
G FAN1 FANCD2 and FANCI associated nuclease 1 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr15:9,395,348...9,435,434
Ensembl chr15:28,433,749...28,473,211 		JBrowse link
G FEN1 flap structure-specific endonuclease 1 enables IEA UniProt
TreeGrafter
Ensembl		 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr11:57,092,270...57,096,828
Ensembl chr11:60,455,474...60,456,616 		JBrowse link
G GEN1 GEN1 Holliday junction 5' flap endonuclease enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr2A:17,735,953...17,766,018
Ensembl chr2A:17,862,070...17,892,048 		JBrowse link
G MGME1 mitochondrial genome maintenance exonuclease 1 enables ISO (PMID:27220468) Reactome PMID:27220468 NCBI chr20:17,928,751...17,950,907
Ensembl chr20:17,907,241...17,929,214 		JBrowse link
G SLC25A16 solute carrier family 25 member 16 enables IEA Ensembl GO_REF:0000107 NCBI chr10:64,898,024...64,956,541
Ensembl chr10:67,506,006...67,549,308
Ensembl chr10:67,506,006...67,549,308 		JBrowse link
G SLX1A SLX1 homolog A, structure-specific endonuclease subunit enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118
class II DNA-(apurinic or apyrimidinic site) endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 enables ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr14:1,329,745...1,332,315
Ensembl chr14:19,381,911...19,384,542 		JBrowse link
crossover junction DNA endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EME1 essential meiotic structure-specific endonuclease 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr17:44,467,537...44,475,883
Ensembl chr17:49,341,791...49,349,959 		JBrowse link
G EME2 essential meiotic structure-specific endonuclease subunit 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr16:395,571...403,233
Ensembl chr16:1,825,622...1,829,557 		JBrowse link
G GEN1 GEN1 Holliday junction 5' flap endonuclease enables IEA Ensembl GO_REF:0000107 NCBI chr2A:17,735,953...17,766,018
Ensembl chr2A:17,862,070...17,892,048 		JBrowse link
G MUS81 MUS81 structure-specific endonuclease subunit enables IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 NCBI chr11:61,220,699...61,226,747
Ensembl chr11:64,549,840...64,555,875 		JBrowse link
G RAD51C RAD51 paralog C enables
contributes_to		 IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:52,769,446...52,808,467
Ensembl chr17:57,621,552...57,660,701 		JBrowse link
G SLX1A SLX1 homolog A, structure-specific endonuclease subunit enables IEA UniProt
TreeGrafter		 GO_REF:0000104 GO_REF:0000118
G TEFM transcription elongation factor, mitochondrial NOT|enables ISO (PMID:21278163) UniProt PMID:21278163 NCBI chr17:25,933,934...25,941,220
Ensembl chr17:25,423,956...25,432,198 		JBrowse link
G XRCC3 X-ray repair cross complementing 3 contributes_to IEA Ensembl GO_REF:0000107 NCBI chr14:84,323,644...84,341,763
Ensembl chr14:104,131,903...104,149,037 		JBrowse link
deoxyribonuclease I activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DICER1 dicer 1, ribonuclease III enables IEA TreeGrafter GO_REF:0000118 NCBI chr14:75,709,029...75,780,779
Ensembl chr14:95,036,385...95,107,940 		JBrowse link
G DNASE1 deoxyribonuclease 1 enables ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:12005024 GO_REF:0000107 GO_REF:0000118 RGD:1298888 NCBI chr16:2,532,281...2,583,408
Ensembl chr16:3,708,189...3,758,615 		JBrowse link
G DNASE1L1 deoxyribonuclease 1 like 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr  X:143,842,920...143,851,795
Ensembl chr  X:153,712,054...153,725,868 		JBrowse link
G DNASE1L2 deoxyribonuclease 1 like 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr16:1,093,669...1,096,123
Ensembl chr16:2,336,768...2,338,391 		JBrowse link
G DNASE1L3 deoxyribonuclease 1L3 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 3:58,127,491...58,146,177
Ensembl chr 3:59,542,243...59,560,363 		JBrowse link
deoxyribonuclease II activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNASE2 deoxyribonuclease 2, lysosomal enables IEA InterPro
TreeGrafter
UniProt
Ensembl		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr19:12,436,898...12,443,530
Ensembl chr19:13,180,073...13,185,650 		JBrowse link
G DNASE2B deoxyribonuclease 2 beta enables ISO
IEA		 RGD
TreeGrafter
UniProt
InterPro		 PMID:10558878 GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 GO_REF:0000118 RGD:70721 NCBI chr 1:116,946,513...116,963,483
Ensembl chr 1:85,807,300...85,824,257 		JBrowse link
DNA endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKLE1 ankyrin repeat and LEM domain containing 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr19:16,769,670...16,775,114
Ensembl chr19:17,744,570...17,750,070 		JBrowse link
G APLF aprataxin and PNKP like factor enables IEA Ensembl GO_REF:0000107 NCBI chr2A:68,509,314...68,629,192
Ensembl chr2A:69,632,459...69,744,611 		JBrowse link
G ASTE1 asteroid homolog 1 enables IEA UniProt GO_REF:0000117 NCBI chr 3:128,098,219...128,111,196
Ensembl chr 3:135,421,044...135,432,284 		JBrowse link
G BIVM basic, immunoglobulin-like variable motif containing enables IEA TreeGrafter
UniProt		 GO_REF:0000117 GO_REF:0000118 NCBI chr13:83,959,365...84,002,223
Ensembl chr13:103,096,344...103,174,182 		JBrowse link
G DFFB DNA fragmentation factor subunit beta enables IEA InterPro GO_REF:0000002 NCBI chr 1:2,529,733...2,559,490
Ensembl chr 1:3,649,729...3,676,896 		JBrowse link
G DNASE1L3 deoxyribonuclease 1L3 ISO RGD PMID:9665719 RGD:728743 NCBI chr 3:58,127,491...58,146,177
Ensembl chr 3:59,542,243...59,560,363 		JBrowse link
G DNASE2 deoxyribonuclease 2, lysosomal ISO RGD PMID:10558878 RGD:70721 NCBI chr19:12,436,898...12,443,530
Ensembl chr19:13,180,073...13,185,650 		JBrowse link
G DNASE2B deoxyribonuclease 2 beta enables IEA Ensembl GO_REF:0000107 NCBI chr 1:116,946,513...116,963,483
Ensembl chr 1:85,807,300...85,824,257 		JBrowse link
G ENDOG endonuclease G enables IEA Ensembl GO_REF:0000107 NCBI chr 9:99,941,856...99,945,957 JBrowse link
G ERCC4 ERCC excision repair 4, endonuclease catalytic subunit contributes_to
enables		 ISO
IEA		 (PMID:8797827) UniProtKB
Ensembl
InterPro		 PMID:8797827 GO_REF:0000002 GO_REF:0000107 NCBI chr16:12,848,334...12,880,480
Ensembl chr16:14,272,417...14,304,496 		JBrowse link
G ERCC5 ERCC excision repair 5, endonuclease enables IEA UniProt
TreeGrafter		 GO_REF:0000117 GO_REF:0000118 NCBI chr13:84,005,950...84,036,710
Ensembl chr13:103,096,344...103,174,182 		JBrowse link
G EXO1 exonuclease 1 enables IEA UniProt GO_REF:0000117 NCBI chr 1:217,410,175...217,451,982
Ensembl chr 1:222,389,684...222,431,556 		JBrowse link
G FEN1 flap structure-specific endonuclease 1 enables IEA UniProt GO_REF:0000117 NCBI chr11:57,092,270...57,096,828
Ensembl chr11:60,455,474...60,456,616 		JBrowse link
G GEN1 GEN1 Holliday junction 5' flap endonuclease enables IEA UniProt GO_REF:0000117 NCBI chr2A:17,735,953...17,766,018
Ensembl chr2A:17,862,070...17,892,048 		JBrowse link
G MRE11 MRE11 homolog, double strand break repair nuclease enables IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr11:89,418,537...89,500,705
Ensembl chr11:92,918,549...92,985,966 		JBrowse link
G N4BP2 NEDD4 binding protein 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 4:34,380,215...34,482,797
Ensembl chr 4:40,253,199...40,336,040 		JBrowse link
G RPS3 ribosomal protein S3 enables ISO (PMID:15707971), (PMID:20605787) UniProt PMID:15707971 PMID:20605787 NCBI chr11:70,460,702...70,466,909
Ensembl chr11:73,762,794...73,768,982 		JBrowse link
G ZRANB3 zinc finger RANBP2-type containing 3 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr2B:24,331,731...24,665,652
Ensembl chr2B:139,234,909...139,577,193 		JBrowse link
DNA endonuclease activity, producing 5'-phosphomonoesters term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENDOV endonuclease V NOT|enables ISO
IEA		 (PMID:23139746), (PMID:23912683) UniProt
Ensembl		 PMID:23139746 PMID:23912683 GO_REF:0000107 NCBI chr17:74,843,661...74,865,960
Ensembl chr17:80,576,450...80,591,856 		JBrowse link
double-stranded DNA endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EME1 essential meiotic structure-specific endonuclease 1 contributes_to IEA Ensembl GO_REF:0000107 NCBI chr17:44,467,537...44,475,883
Ensembl chr17:49,341,791...49,349,959 		JBrowse link
G EME2 essential meiotic structure-specific endonuclease subunit 2 contributes_to IEA Ensembl GO_REF:0000107 NCBI chr16:395,571...403,233
Ensembl chr16:1,825,622...1,829,557 		JBrowse link
G MUS81 MUS81 structure-specific endonuclease subunit enables IEA Ensembl GO_REF:0000107 NCBI chr11:61,220,699...61,226,747
Ensembl chr11:64,549,840...64,555,875 		JBrowse link
G RAG1 recombination activating 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr11:36,483,697...36,546,242
Ensembl chr11:36,412,420...36,422,904 		JBrowse link
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SND1 staphylococcal nuclease and tudor domain containing 1 enables IEA UniProt GO_REF:0000003 NCBI chr 7:119,647,536...120,084,110
Ensembl chr 7:132,302,235...132,738,223 		JBrowse link
endoribonuclease activity, cleaving miRNA-paired mRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGO2 argonaute RISC catalytic component 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 8:137,192,037...137,308,059
Ensembl chr 8:140,287,647...140,361,125 		JBrowse link
G AGO3 argonaute RISC catalytic component 3 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:35,196,371...35,322,220
Ensembl chr 1:36,372,221...36,497,190 		JBrowse link
endoribonuclease activity, cleaving siRNA-paired mRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGO2 argonaute RISC catalytic component 2 enables IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 8:137,192,037...137,308,059
Ensembl chr 8:140,287,647...140,361,125 		JBrowse link
endoribonuclease inhibitor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCE1 ATP binding cassette subfamily E member 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 4:137,445,210...137,476,309
Ensembl chr 4:149,105,912...149,137,028 		JBrowse link
G TMBIM6 transmembrane BAX inhibitor motif containing 6 enables IEA Ensembl GO_REF:0000107 NCBI chr12:38,986,844...39,010,307
Ensembl chr12:39,879,951...39,902,303 		JBrowse link
flap endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EXO1 exonuclease 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:217,410,175...217,451,982
Ensembl chr 1:222,389,684...222,431,556 		JBrowse link
G FEN1 flap structure-specific endonuclease 1 enables IEA Ensembl GO_REF:0000107 NCBI chr11:57,092,270...57,096,828
Ensembl chr11:60,455,474...60,456,616 		JBrowse link
phosphodiesterase decapping endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT12 nudix hydrolase 12 enables IEA Ensembl GO_REF:0000107 NCBI chr 5:98,903,740...98,917,763
Ensembl chr 5:104,601,373...104,617,925 		JBrowse link
G NUDT16 nudix hydrolase 16 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 3:128,466,119...128,473,186
Ensembl chr 3:135,788,354...135,790,038 		JBrowse link
ribonuclease A activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RNASE8 ribonuclease A family member 8 enables IEA Ensembl GO_REF:0000107 NCBI chr14:1,872,595...1,873,331
Ensembl chr14:19,954,680...19,955,147 		JBrowse link
ribonuclease III activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DICER1 dicer 1, ribonuclease III enables IEA Ensembl
TreeGrafter
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000118 NCBI chr14:75,709,029...75,780,779
Ensembl chr14:95,036,385...95,107,940 		JBrowse link
G DROSHA drosha ribonuclease III enables IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:78,813,923...78,945,149
Ensembl chr 5:84,194,546...84,322,310 		JBrowse link
G MRPL44 mitochondrial ribosomal protein L44 enables IEA InterPro GO_REF:0000002 NCBI chr2B:111,203,655...111,213,888
Ensembl chr2B:229,779,983...229,790,240 		JBrowse link
ribonuclease MRP activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RNase_MRP RNase MRP enables IEA RNAcentral GO_REF:0000115 Ensembl chr 9:25,360,860...25,361,126 JBrowse link
G RNase_MRP RNase MRP enables IEA RNAcentral GO_REF:0000115 Ensembl chr 9:36,312,175...36,312,437 JBrowse link
G RPP40 ribonuclease P/MRP subunit p40 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 6:4,828,155...4,838,680
Ensembl chr 6:5,015,953...5,024,540 		JBrowse link
ribonuclease P activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POP1 POP1 homolog, ribonuclease P/MRP subunit contributes_to IEA Ensembl GO_REF:0000107 NCBI chr 8:94,754,028...94,796,374
Ensembl chr 8:96,944,588...96,979,328 		JBrowse link
G POP4 POP4 homolog, ribonuclease P/MRP subunit enables
contributes_to		 IEA UniProt
Ensembl		 GO_REF:0000003 GO_REF:0000107 NCBI chr19:26,535,196...26,544,747
Ensembl chr19:35,296,084...35,307,002 		JBrowse link
G POP5 POP5 homolog, ribonuclease P/MRP subunit enables
contributes_to		 IEA UniProt
Ensembl		 GO_REF:0000003 GO_REF:0000107 NCBI chr12:118,162,497...118,165,472
Ensembl chr12:121,535,005...121,537,350 		JBrowse link
G POP7 POP7 homolog, ribonuclease P/MRP subunit enables
contributes_to		 IEA UniProt
Ensembl		 GO_REF:0000003 GO_REF:0000104 GO_REF:0000107 NCBI chr 7:92,722,839...92,734,708
Ensembl chr 7:106,134,766...106,135,188 		JBrowse link
G PRORP protein only RNase P catalytic subunit enables IEA UniProt
TreeGrafter
Ensembl		 GO_REF:0000003 GO_REF:0000107 GO_REF:0000118 NCBI chr14:15,871,707...16,027,634
Ensembl chr14:34,056,620...34,209,657 		JBrowse link
G RNaseP_nuc Nuclear RNase P enables IEA RNAcentral GO_REF:0000115 Ensembl chr 4:161,147,214...161,147,535 JBrowse link
G RNaseP_nuc Nuclear RNase P enables IEA RNAcentral GO_REF:0000115 Ensembl chr14:19,268,479...19,268,811 JBrowse link
G RPP14 ribonuclease P/MRP subunit p14 enables
contributes_to		 IEA UniProt
Ensembl		 GO_REF:0000003 GO_REF:0000107 NCBI chr 3:58,239,048...58,252,810
Ensembl chr 3:59,653,220...59,666,531
Ensembl chr 3:59,653,220...59,666,531 		JBrowse link
G RPP21 ribonuclease P subunit p21 contributes_to ISO (PMID:30454648) UniProt PMID:30454648 NCBI chr 6:30,122,996...30,124,784
Ensembl chr 6:30,975,260...30,995,764 		JBrowse link
G RPP25 ribonuclease P and MRP subunit p25 contributes_to IEA Ensembl GO_REF:0000107 NCBI chr15:53,895,547...53,897,922
Ensembl chr15:73,513,375...73,513,974 		JBrowse link
G RPP30 ribonuclease P/MRP subunit p30 contributes_to IEA Ensembl GO_REF:0000107 NCBI chr10:87,611,699...87,646,239
Ensembl chr10:91,138,993...91,170,517 		JBrowse link
G RPP38 ribonuclease P/MRP subunit p38 enables
contributes_to		 IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:15,413,026...15,420,170
Ensembl chr10:15,700,027...15,703,046 		JBrowse link
G RPP40 ribonuclease P/MRP subunit p40 enables
contributes_to		 IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:4,828,155...4,838,680
Ensembl chr 6:5,015,953...5,024,540 		JBrowse link
ribonuclease T2 activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RNASET2 ribonuclease T2 enables IEA InterPro GO_REF:0000002 NCBI chr 6:164,895,396...164,923,008
Ensembl chr 6:169,872,780...169,899,599 		JBrowse link
RNA endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGO1 argonaute RISC component 1 NOT|enables ISO (PMID:23809764) UniProt PMID:23809764 NCBI chr 1:35,148,984...35,196,252
Ensembl chr 1:36,324,733...36,360,832 		JBrowse link
G AGO2 argonaute RISC catalytic component 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 8:137,192,037...137,308,059
Ensembl chr 8:140,287,647...140,361,125 		JBrowse link
G AGO3 argonaute RISC catalytic component 3 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:35,196,371...35,322,220
Ensembl chr 1:36,372,221...36,497,190 		JBrowse link
G ANKZF1 ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1 enables IEA Ensembl GO_REF:0000107 NCBI chr2B:106,487,377...106,494,258
Ensembl chr2B:225,078,322...225,085,205 		JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 ISO RGD PMID:19401441 RGD:2315668 NCBI chr14:1,329,745...1,332,315
Ensembl chr14:19,381,911...19,384,542 		JBrowse link
G CPSF3 cleavage and polyadenylation specific factor 3 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr2A:9,413,517...9,462,758
Ensembl chr2A:9,576,871...9,626,193 		JBrowse link
G DICER1 dicer 1, ribonuclease III enables IEA Ensembl GO_REF:0000107 NCBI chr14:75,709,029...75,780,779
Ensembl chr14:95,036,385...95,107,940 		JBrowse link
G DROSHA drosha ribonuclease III enables IEA Ensembl
UniProt		 GO_REF:0000107 GO_REF:0000117 NCBI chr 5:78,813,923...78,945,149
Ensembl chr 5:84,194,546...84,322,310 		JBrowse link
G ENDOG endonuclease G enables IEA TreeGrafter GO_REF:0000118 NCBI chr 9:99,941,856...99,945,957 JBrowse link
G ENDOU endonuclease, poly(U) specific enables IEA InterPro
TreeGrafter
UniProt
Ensembl		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr12:41,003,037...41,024,127
Ensembl chr12:41,882,483...41,897,119 		JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 enables IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr17:58,132,889...58,224,012
Ensembl chr17:63,226,949...63,317,825 		JBrowse link
G ERN2 endoplasmic reticulum to nucleus signaling 2 enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr16:14,397,697...14,420,618
Ensembl chr16:23,940,716...23,963,894 		JBrowse link
G EXOG exo/endonuclease G enables IEA TreeGrafter GO_REF:0000118 NCBI chr 3:38,392,968...38,422,990
Ensembl chr 3:38,674,970...38,703,750 		JBrowse link
G INTS11 integrator complex subunit 11 enables IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:66,280...81,854
Ensembl chr 1:1,266,581...1,281,430 		JBrowse link
G KHNYN KH and NYN domain containing enables IEA TreeGrafter GO_REF:0000118 NCBI chr14:5,205,650...5,216,436
Ensembl chr14:23,329,932...23,340,966 		JBrowse link
G LACTB2 lactamase beta 2 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:67,162,667...67,194,560
Ensembl chr 8:68,824,302...68,854,833 		JBrowse link
G MBLAC1 metallo-beta-lactamase domain containing 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 7:92,162,025...92,163,678
Ensembl chr 7:105,595,781...105,596,582 		JBrowse link
G NOB1 NIN1 (RPN12) binding protein 1 homolog enables IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 NCBI chr16:50,122,905...50,135,096
Ensembl chr16:69,506,425...69,517,932 		JBrowse link
G NYNRIN NYN domain and retroviral integrase containing enables IEA TreeGrafter GO_REF:0000118 NCBI chr14:5,174,889...5,195,706
Ensembl chr14:23,298,139...23,318,905 		JBrowse link
G PIWIL1 piwi like RNA-mediated gene silencing 1 enables IEA Ensembl GO_REF:0000107 NCBI chr12:127,951,178...127,986,173
Ensembl chr12:132,169,820...132,199,374 		JBrowse link
G PIWIL2 piwi like RNA-mediated gene silencing 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 8:21,520,166...21,608,374
Ensembl chr 8:18,463,173...18,544,186 		JBrowse link
G PIWIL4 piwi like RNA-mediated gene silencing 4 NOT|enables ISO (PMID:22020280) UniProt PMID:22020280 NCBI chr11:89,572,252...89,628,251
Ensembl chr11:93,097,709...93,150,981 		JBrowse link
G PPP1R8 protein phosphatase 1 regulatory subunit 8 enables ISO (PMID:10432294), (PMID:9153239) UniProt PMID:9153239 PMID:10432294 NCBI chr 1:27,092,588...27,113,399
Ensembl chr 1:28,133,358...28,152,588 		JBrowse link
G RCL1 RNA terminal phosphate cyclase like 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 9:4,626,981...4,695,444
Ensembl chr 9:4,813,750...4,881,423 		JBrowse link
G RNASEK ribonuclease K enables IEA InterPro GO_REF:0000002 NCBI chr17:7,043,269...7,045,379
Ensembl chr17:7,031,283...7,033,393 		JBrowse link
G RNASET2 ribonuclease T2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 6:164,895,396...164,923,008
Ensembl chr 6:169,872,780...169,899,599 		JBrowse link
G SLFN11 schlafen family member 11 enables ISO PMID:29563550 UniProt PMID:29563550 RGD:13601999 NCBI chr17:21,412,361...21,436,650
Ensembl chr17:21,715,569...21,727,019 		JBrowse link
G SLFN13 schlafen family member 13 enables IEA Ensembl GO_REF:0000107 NCBI chr17:21,343,027...21,354,521
Ensembl chr17:21,641,078...21,646,159 		JBrowse link
G SLFN14 schlafen family member 14 enables IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:21,232,934...21,250,368
Ensembl chr17:21,530,009...21,539,589 		JBrowse link
G SMG6 SMG6 nonsense mediated mRNA decay factor enables IEA Ensembl GO_REF:0000107 NCBI chr17:2,050,825...2,294,892
Ensembl chr17:1,937,630...2,179,535 		JBrowse link
G SND1 staphylococcal nuclease and tudor domain containing 1 enables IEA Ensembl
UniProt		 GO_REF:0000104 GO_REF:0000107 NCBI chr 7:119,647,536...120,084,110
Ensembl chr 7:132,302,235...132,738,223 		JBrowse link
G YBEY ybeY metalloendoribonuclease enables IEA Ensembl GO_REF:0000107 NCBI chr21:32,628,599...32,638,914
Ensembl chr21:45,879,824...45,888,717 		JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:36,743,341...36,753,261
Ensembl chr 1:38,093,917...38,103,556 		JBrowse link
G ZC3H12B zinc finger CCCH-type containing 12B enables IEA TreeGrafter GO_REF:0000118 NCBI chr  X:54,162,659...54,623,859
Ensembl chr  X:64,563,916...64,699,055 		JBrowse link
G ZC3H12C zinc finger CCCH-type containing 12C enables IEA TreeGrafter GO_REF:0000118 NCBI chr11:104,975,798...105,054,382
Ensembl chr11:108,859,581...108,899,858 		JBrowse link
G ZC3H12D zinc finger CCCH-type containing 12D enables IEA TreeGrafter GO_REF:0000118 NCBI chr 6:147,266,039...147,304,289
Ensembl chr 6:151,974,485...151,999,898 		JBrowse link
RNA endonuclease activity, producing 3'-phosphomonoesters term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RIDA reactive intermediate imine deaminase A ISO RGD PMID:10400702 RGD:9685547 NCBI chr 8:94,739,120...94,753,934
Ensembl chr 8:96,923,776...96,938,512 		JBrowse link
RNA endonuclease activity, producing 5'-phosphomonoesters term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGO2 argonaute RISC catalytic component 2 enables IEA UniProt GO_REF:0000104 NCBI chr 8:137,192,037...137,308,059
Ensembl chr 8:140,287,647...140,361,125 		JBrowse link
G DICER1 dicer 1, ribonuclease III enables IEA InterPro GO_REF:0000002 NCBI chr14:75,709,029...75,780,779
Ensembl chr14:95,036,385...95,107,940 		JBrowse link
G ELAC1 elaC ribonuclease Z 1 enables IEA InterPro GO_REF:0000002 NCBI chr18:44,339,868...44,359,150
Ensembl chr18:47,692,305...47,706,019 		JBrowse link
G ENDOV endonuclease V enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:74,843,661...74,865,960
Ensembl chr17:80,576,450...80,591,856 		JBrowse link
G PLD6 phospholipase D family member 6 enables IEA TreeGrafter GO_REF:0000118 NCBI chr17:34,084,634...34,091,470
Ensembl chr17:39,016,859...39,023,398 		JBrowse link
RNA lariat debranching enzyme activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CWF19L1 CWF19 like cell cycle control factor 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr10:96,838,064...96,873,478
Ensembl chr10:100,319,979...100,354,599 		JBrowse link
RNA lariat debranching enzyme activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DBR1 debranching RNA lariats 1 enables IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chr 3:135,188,636...135,202,934
Ensembl chr 3:142,639,712...142,653,016 		JBrowse link
RNA-DNA hybrid ribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FEN1 flap structure-specific endonuclease 1 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:57,092,270...57,096,828
Ensembl chr11:60,455,474...60,456,616 		JBrowse link
G NYNRIN NYN domain and retroviral integrase containing enables IEA InterPro GO_REF:0000002 NCBI chr14:5,174,889...5,195,706
Ensembl chr14:23,298,139...23,318,905 		JBrowse link
G RNASEH1 ribonuclease H1 enables IEA UniProt
TreeGrafter
Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chr2A:3,550,303...3,578,161
Ensembl chr2A:3,482,772...3,496,978 		JBrowse link
G RNASEH2A ribonuclease H2 subunit A enables IEA Ensembl
TreeGrafter
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr19:12,363,721...12,375,316
Ensembl chr19:13,112,242...13,119,514 		JBrowse link
single-stranded DNA endodeoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASTE1 asteroid homolog 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 3:128,098,219...128,111,196
Ensembl chr 3:135,421,044...135,432,284 		JBrowse link
G DCLRE1C DNA cross-link repair 1C enables IEA Ensembl GO_REF:0000107 NCBI chr10:14,901,335...14,956,947
Ensembl chr10:15,236,558...15,269,043 		JBrowse link
G ENDOG endonuclease G enables IEA TreeGrafter GO_REF:0000118 NCBI chr 9:99,941,856...99,945,957 JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit contributes_to IEA Ensembl GO_REF:0000107 NCBI chr19:42,356,039...42,427,754
Ensembl chr19:50,951,674...50,968,430 		JBrowse link
G ERCC4 ERCC excision repair 4, endonuclease catalytic subunit enables IEA TreeGrafter GO_REF:0000118 NCBI chr16:12,848,334...12,880,480
Ensembl chr16:14,272,417...14,304,496 		JBrowse link
G EXOG exo/endonuclease G enables IEA TreeGrafter GO_REF:0000118 NCBI chr 3:38,392,968...38,422,990
Ensembl chr 3:38,674,970...38,703,750 		JBrowse link
G LOC100986203 histone-lysine N-methyltransferase SETMAR enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:4,256,539...4,271,593
Ensembl chr 3:4,357,890...4,371,791 		JBrowse link
G MRE11 MRE11 homolog, double strand break repair nuclease enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:89,418,537...89,500,705
Ensembl chr11:92,918,549...92,985,966 		JBrowse link
G PTBP1 polypyrimidine tract binding protein 1 ISO RGD PMID:12269805 RGD:633791 NCBI chr19:319,953...334,945 JBrowse link
G RAD50 RAD50 double strand break repair protein contributes_to IEA Ensembl GO_REF:0000107 NCBI chr 5:127,972,630...128,059,911
Ensembl chr 5:134,134,495...134,222,261 		JBrowse link
G RBBP8 RB binding protein 8, endonuclease enables IEA Ensembl GO_REF:0000107 NCBI chr18:16,181,652...16,274,597
Ensembl chr18:19,811,989...19,903,522 		JBrowse link
site-specific endodeoxyribonuclease activity, specific for altered base term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 enables ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr14:1,329,745...1,332,315
Ensembl chr14:19,381,911...19,384,542 		JBrowse link
G SLC25A16 solute carrier family 25 member 16 enables IEA Ensembl GO_REF:0000107 NCBI chr10:64,898,024...64,956,541
Ensembl chr10:67,506,006...67,549,308
Ensembl chr10:67,506,006...67,549,308 		JBrowse link
tRNA-intron lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TSEN2 tRNA splicing endonuclease subunit 2 enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 GO_REF:0000118 NCBI chr 3:12,410,885...12,463,932
Ensembl chr 3:12,759,375...12,800,201 		JBrowse link
G TSEN34 tRNA splicing endonuclease subunit 34 enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 GO_REF:0000118 NCBI chr19:51,121,560...51,125,768
Ensembl chr19:59,964,174...59,968,453 		JBrowse link
Term paths to the root