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ONTOLOGY REPORT - ANNOTATIONS

Term:endonuclease activity
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Accession:GO:0004519 term browser browse the term
Definition:Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
Synonyms:xref: reactome:R-HSA-5358512 "MLH1:PMS2 makes single strand incision near insertion/deletion loop of 2 bases or more";   reactome:R-HSA-5358518 "MLH1:PMS2 makes single strand incision near 1-2 base mismatch";   reactome:R-HSA-5690990 "5'- incision of DNA by ERCC1:ERCC4 in GG-NER";   reactome:R-HSA-5693533 "DCLRE1C (ARTEMIS) processes DNA DSB ends";   reactome:R-HSA-72180 "Cleavage of mRNA at the 3'-end"


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endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ago2 argonaute RISC catalytic component 2 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:106,907,209...106,994,124
Ensembl chr 7:105,029,120...105,104,974 		JBrowse link
G Ago3 argonaute RISC catalytic component 3 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:138,632,367...138,714,230
Ensembl chr 5:138,639,569...138,714,230 		JBrowse link
G Alkbh2 alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase NOT|enables ISO (PMID:16174769) RGD PMID:16174769 NCBI chr12:42,494,187...42,500,929
Ensembl chr12:42,496,300...42,500,914 		JBrowse link
G Alkbh3 alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase NOT|enables ISO (PMID:16174769) RGD PMID:16174769 NCBI chr 3:100,394,942...100,429,466
Ensembl chr 3:79,939,600...79,972,000 		JBrowse link
G Ang2 angiogenin, ribonuclease A family, member 2 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr15:26,871,842...26,889,421
Ensembl chr15:24,398,419...24,398,922 		JBrowse link
G Ankle1 ankyrin repeat and LEM domain containing 1 enables ISO
IEA		 (PMID:22399800)
GO_REF:0000002
GO_REF:0000107		 RGD
InterPro
Ensembl		 PMID:22399800 GO_REF:0000002 GO_REF:0000107 NCBI chr16:18,109,865...18,116,999
Ensembl chr16:18,076,492...18,083,729 		JBrowse link
G Ankzf1 ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 9:84,136,862...84,143,830
Ensembl chr 9:76,688,194...76,696,469 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 enables ISO
IEA		 (PMID:11478795)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000043		 RGD
Ensembl
InterPro
UniProt		 PMID:11478795 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 NCBI chr15:26,618,146...26,620,330
Ensembl chr15:24,144,362...24,146,785 		JBrowse link
G Apex2 apurinic/apyrimidinic endodeoxyribonuclease 2 enables IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr  X:19,425,684...19,508,459
Ensembl chr  X:19,487,419...19,508,439 		JBrowse link
G Apex2l1 APEX nuclease (apurinic/apyrimidinic endonuclease) 2-like 1 enables IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr14:67,166,252...67,168,138
Ensembl chr14:67,166,530...67,168,080 		JBrowse link
G Dclre1c DNA cross-link repair 1C enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:74,775,828...74,810,089
Ensembl chr17:74,776,935...74,809,186 		JBrowse link
G Dicer1 dicer 1 ribonuclease III enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 6:129,392,298...129,457,252
Ensembl chr 6:123,631,250...123,693,965 		JBrowse link
G Dis3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease enables ISO
IEA
IBA		 (PMID:20531386)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:20531386 GO_REF:0000033 GO_REF:0000107 NCBI chr15:82,231,922...82,258,299
Ensembl chr15:75,823,436...75,850,642 		JBrowse link
G Dna2 DNA replication helicase/nuclease 2 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr20:25,661,652...25,690,598
Ensembl chr20:25,662,055...25,716,319 		JBrowse link
G Dnase1 deoxyribonuclease 1 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:12,005,305...12,030,615
Ensembl chr10:11,498,931...11,501,869 		JBrowse link
G Dnase1l1 deoxyribonuclease 1-like 1 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr  X:157,208,230...157,216,812
Ensembl chr  X:152,056,942...152,065,518 		JBrowse link
G Dnase1l2 deoxyribonuclease 1 like 2 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:13,976,012...13,978,574
Ensembl chr10:13,471,479...13,473,763 		JBrowse link
G Dnase1l3 deoxyribonuclease 1L3 enables ISO
IEA		 (PMID:12050166)
GO_REF:0000107
GO_REF:0000043		 RGD
Ensembl
UniProt		 PMID:12050166 GO_REF:0000043 GO_REF:0000107 NCBI chr15:19,351,683...19,378,536
Ensembl chr15:16,922,335...16,948,317 		JBrowse link
G Dnase2 deoxyribonuclease 2, lysosomal enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr19:40,149,505...40,152,225
Ensembl chr19:23,244,664...23,247,376 		JBrowse link
G Dnase2b deoxyribonuclease 2 beta enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:238,131,182...238,168,041
Ensembl chr 2:235,470,919...235,486,295 		JBrowse link
G Drosha drosha ribonuclease III enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:63,591,885...63,703,688
Ensembl chr 2:61,864,970...61,976,688 		JBrowse link
G Ear1 eosinophil-associated, ribonuclease A family, member 1 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr15:27,028,785...27,029,694
Ensembl chr15:24,555,298...24,556,199 		JBrowse link
G Ear1l1 eosinophil-associated, ribonuclease A family, member 1 like 1 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr15:26,960,332...26,961,207
Ensembl chr15:24,486,826...24,487,691 		JBrowse link
G Elac1 elaC ribonuclease Z 1 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr18:69,596,475...69,617,206
Ensembl chr18:67,323,583...67,340,936 		JBrowse link
G Elac2 elaC ribonuclease Z 2 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:50,131,449...50,154,755
Ensembl chr10:49,632,378...49,655,614 		JBrowse link
G Eme1 essential meiotic structure-specific endonuclease 1 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:79,586,718...79,595,515
Ensembl chr10:79,586,729...79,595,435 		JBrowse link
G Eme2 essential meiotic structure-specific endonuclease subunit 2 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:14,413,661...14,420,489
Ensembl chr10:13,913,221...13,915,968 		JBrowse link
G Endog endonuclease G enables IEA GO_REF:0000043
GO_REF:0000104		 UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr 3:33,846,935...33,849,531
Ensembl chr 3:13,449,086...13,451,932 		JBrowse link
G Endou endonuclease, poly(U)-specific enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:130,723,972...130,745,672
Ensembl chr 7:128,844,862...128,866,596 		JBrowse link
G Endov endonuclease V enables IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr10:104,760,059...104,777,732
Ensembl chr10:104,760,137...104,775,969 		JBrowse link
G ENSRNOG00000065207 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr 4:104,244,335...104,246,214 JBrowse link
G ENSRNOG00000067229 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr 4:83,921,470...83,930,590 JBrowse link
G ENSRNOG00000067248 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr 9:77,055,483...77,060,879 JBrowse link
G ENSRNOG00000068406 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr 4:51,689,402...51,693,026 JBrowse link
G ENSRNOG00000069140 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr 4:12,337,547...12,343,488 JBrowse link
G ENSRNOG00000069624 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr 4:147,700,824...147,706,682 JBrowse link
G ENSRNOG00000070353 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr10:2,554,934...2,602,472 JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:2,926,085...2,958,176
Ensembl chr10:2,419,038...2,448,369
Ensembl chr10:2,419,038...2,448,369 		JBrowse link
G Ercc4l1 excision repair cross-complementing rodent repair deficiency, complementation group 4-like 1 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:954,927...983,651
Ensembl chr10:954,977...983,174 		JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease enables ISO
IEA		 (PMID:32522879), (PMID:32821917)
GO_REF:0000043
GO_REF:0000002		 RGD
UniProt
InterPro		 PMID:32522879 PMID:32821917 GO_REF:0000002 GO_REF:0000043 NCBI chr 9:53,801,471...53,846,611
Ensembl chr 9:46,309,389...46,354,472 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 enables ISO
IEA		 (PMID:11850408)
GO_REF:0000107		 RGD
Ensembl		 PMID:11850408 GO_REF:0000107 NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Ern2 endoplasmic reticulum to nucleus signaling 2 enables ISO
IEA		 (PMID:11175748)
GO_REF:0000107		 RGD
Ensembl		 PMID:11175748 GO_REF:0000107 NCBI chr 1:186,153,115...186,174,521
Ensembl chr 1:176,726,454...176,743,289 		JBrowse link
G Exo1 exonuclease 1 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr13:90,341,947...90,366,861
Ensembl chr13:87,809,810...87,834,654 		JBrowse link
G Exog exo/endonuclease G enables ISO (PMID:18187503) RGD PMID:18187503 NCBI chr 8:128,062,688...128,082,529
Ensembl chr 8:119,185,136...119,204,672 		JBrowse link
G Fen1 flap structure-specific endonuclease 1 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:216,270,016...216,274,873
Ensembl chr 1:206,844,884...206,850,003 		JBrowse link
G Lactb2 lactamase, beta 2 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:10,352,165...10,374,928
Ensembl chr 5:5,569,067...5,596,429 		JBrowse link
G Las1l LAS1-like, ribosome biogenesis factor enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:60,851,969...60,873,717
Ensembl chr  X:60,851,962...60,873,687 		JBrowse link
G LOC100361866 eosinophil cationic protein-like enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr15:27,009,206...27,010,076
Ensembl chr15:24,535,700...24,536,592 		JBrowse link
G LOC134480950 igE-binding protein-like enables IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr11:12,193,771...12,199,421 JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease enables IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr 8:19,900,211...19,961,906
Ensembl chr 8:11,632,354...11,678,279 		JBrowse link
G Mus81 MUS81 structure-specific endonuclease subunit enables ISO
IEA		 (PMID:19595721)
GO_REF:0000107
GO_REF:0000043		 RGD
Ensembl
UniProt		 PMID:19595721 GO_REF:0000043 GO_REF:0000107 NCBI chr 1:212,219,793...212,225,214
Ensembl chr 1:202,790,466...202,795,843 		JBrowse link
G N4bp2 NEDD4 binding protein 2 enables ISO
IEA
IBA		 (PMID:12730195)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:12730195 GO_REF:0000033 GO_REF:0000107 NCBI chr14:42,342,690...42,479,861
Ensembl chr14:42,409,510...42,483,960 		JBrowse link
G Neil1 nei-like DNA glycosylase 1 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 8:57,550,142...57,556,884
Ensembl chr 8:57,550,147...57,556,258 		JBrowse link
G Nob1 NIN1 (RPN12) binding protein 1 homolog enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr19:35,322,803...35,335,354
Ensembl chr19:35,322,669...35,346,815 		JBrowse link
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 9:48,243,365...48,253,316
Ensembl chr 9:48,237,572...48,253,211 		JBrowse link
G Rag1 recombination activating 1 enables ISO
IEA		 (PMID:10601033), (PMID:19396172)
GO_REF:0000107
GO_REF:0000104
GO_REF:0000043
GO_REF:0000002		 RGD
Ensembl
UniProt
InterPro		 PMID:10601033 PMID:19396172 GO_REF:0000002 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107 NCBI chr 3:108,372,087...108,383,184
Ensembl chr 3:87,917,004...87,928,291 		JBrowse link
G Rbbp8 RB binding protein 8, endonuclease enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr18:3,198,188...3,263,643
Ensembl chr18:2,921,286...2,988,846 		JBrowse link
G Rexo4 REX4 homolog, 3'-5' exonuclease enables ISO
IEA		 (PMID:21602889)
GO_REF:0000107		 RGD
Ensembl		 PMID:21602889 GO_REF:0000107 NCBI chr 3:30,678,729...30,692,376
Ensembl chr 3:10,280,654...10,290,996 		JBrowse link
G Rnase1 ribonuclease A family member 1, pancreatic enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr15:24,361,924...24,363,633
Ensembl chr15:24,361,927...24,363,624 		JBrowse link
G Rnase17 ribonuclease 17 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr15:26,972,687...26,973,646
Ensembl chr15:24,499,178...24,500,095 		JBrowse link
G Rnase1l1 ribonuclease, RNase A family, 1-like 1 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr15:24,338,216...24,339,934
Ensembl chr15:24,338,479...24,338,931 		JBrowse link
G Rnase1l2 ribonuclease, RNase A family, 1-like 2 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr15:24,421,825...24,423,513
Ensembl chr15:24,421,859...24,423,611 		JBrowse link
G Rnase2 ribonuclease A family member 2 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr15:26,923,125...26,923,934
Ensembl chr15:24,449,611...24,450,479 		JBrowse link
G Rnase3 ribonuclease A family member 3 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr15:26,985,399...26,986,269
Ensembl chr15:24,511,891...24,512,790 		JBrowse link
G Rnase4 ribonuclease A family member 4 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr15:26,786,287...26,803,634
Ensembl chr15:24,312,464...24,330,117 		JBrowse link
G Rnase6 ribonuclease A family member 6 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr15:26,827,896...26,830,807
Ensembl chr15:24,354,303...24,357,328 		JBrowse link
G Rnaseh1 ribonuclease H1 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 6:45,282,849...45,292,258
Ensembl chr 6:45,282,854...45,292,236 		JBrowse link
G Rnaseh2a ribonuclease H2, subunit A enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr19:23,186,325...23,196,045
Ensembl chr19:23,186,383...23,196,041 		JBrowse link
G Setmar SET domain and mariner transposase fusion gene enables ISO (PMID:20620605), (PMID:21491884), (PMID:22231448) RGD PMID:20620605 PMID:21491884 PMID:22231448 NCBI chr 4:142,602,066...142,614,208
Ensembl chr 4:141,046,069...141,058,197 		JBrowse link
G Slc25a16 solute carrier family 25 member 16 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr20:25,659,847...25,717,080
Ensembl chr20:25,662,055...25,716,319 		JBrowse link
G Slfn9 schlafen family member 9 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:68,406,641...68,420,062
Ensembl chr10:67,909,106...67,925,383 		JBrowse link
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:190,716,759...190,722,307
Ensembl chr 1:181,283,921...181,291,775 		JBrowse link
G Smg6 SMG6 nonsense mediated mRNA decay factor enables IEA GO_REF:0000104
GO_REF:0000043		 UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr10:60,284,628...60,512,738
Ensembl chr10:59,786,258...60,014,395 		JBrowse link
G Snd1 staphylococcal nuclease and tudor domain containing 1 enables ISO
IEA		 (PMID:18453631)
GO_REF:0000107
GO_REF:0000043		 RGD
Ensembl
UniProt		 PMID:18453631 GO_REF:0000043 GO_REF:0000107 NCBI chr 4:58,060,689...58,459,926
Ensembl chr 4:57,095,208...57,530,843 		JBrowse link
G Ybey ybeY metalloendoribonuclease enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr20:12,165,192...12,174,713
Ensembl chr20:12,165,237...12,174,713 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:142,661,193...142,670,051
Ensembl chr 5:137,376,564...137,385,351 		JBrowse link
G Zc3h12b zinc finger CCCH-type containing 12B enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr  X:60,615,616...60,849,278
Ensembl chr  X:60,615,682...60,844,832 		JBrowse link
G Zc3h12c zinc finger CCCH type containing 12C enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 8:61,340,446...61,404,932
Ensembl chr 8:52,448,320...52,504,315 		JBrowse link
G Zc3h12d zinc finger CCCH type containing 12D enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:4,131,674...4,169,192
Ensembl chr 1:2,314,324...2,348,819 		JBrowse link
G Zfp873 zinc finger protein 873 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:7,926,951...7,959,822
Ensembl chr 7:7,926,957...7,951,803 		JBrowse link
G Zranb3 zinc finger RANBP2-type containing 3 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:41,993,110...42,148,298
Ensembl chr13:39,440,889...39,595,670 		JBrowse link
3' overhang single-stranded DNA endodeoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aste1 asteroid homolog 1 enables ISO
IEA		 (PMID:34354233)
GO_REF:0000107		 RGD
Ensembl		 PMID:34354233 GO_REF:0000107 NCBI chr 8:114,905,349...114,923,775
Ensembl chr 8:106,026,515...106,044,430 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit contributes_to ISO (PMID:14690602) RGD PMID:14690602 NCBI chr 1:88,099,308...88,135,966
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit contributes_to ISO (PMID:14690602) RGD PMID:14690602 NCBI chr10:2,926,085...2,958,176
Ensembl chr10:2,419,038...2,448,369
Ensembl chr10:2,419,038...2,448,369 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 contributes_to ISO
IEA		 (PMID:14690602)
GO_REF:0000107		 RGD
Ensembl		 PMID:14690602 GO_REF:0000107 NCBI chr 1:89,268,721...89,296,619
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
G Xrcc4 X-ray repair cross complementing 4 contributes_to ISO (PMID:14690602) RGD PMID:14690602 NCBI chr 2:22,686,506...22,932,929
Ensembl chr 2:20,951,200...21,197,808 		JBrowse link
3'-flap endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mus81 MUS81 structure-specific endonuclease subunit enables ISO
IBA
IEA		 (PMID:19595721)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:19595721 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:212,219,793...212,225,214
Ensembl chr 1:202,790,466...202,795,843 		JBrowse link
3'-tRNA processing endoribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Elac1 elaC ribonuclease Z 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:69,596,475...69,617,206
Ensembl chr18:67,323,583...67,340,936 		JBrowse link
G Elac2 elaC ribonuclease Z 2 enables IEA
IBA		 GO_REF:0000003
GO_REF:0000033
GO_REF:0000002		 UniProt
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr10:50,131,449...50,154,755
Ensembl chr10:49,632,378...49,655,614 		JBrowse link
5'-flap endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dna2 DNA replication helicase/nuclease 2 enables ISS
IEA
IBA		 GO_REF:0000024
GO_REF:0000107
GO_REF:0000033
GO_REF:0000104		 UniProt
Ensembl
GO_Central		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 NCBI chr20:25,661,652...25,690,598
Ensembl chr20:25,662,055...25,716,319 		JBrowse link
G Exo1 exonuclease 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:90,341,947...90,366,861
Ensembl chr13:87,809,810...87,834,654 		JBrowse link
G Fan1 FANCD2 and FANCI associated nuclease 1 enables ISO
IBA		 (PMID:20603015), (PMID:20603016), (PMID:20603073), (PMID:24981866)
GO_REF:0000033		 RGD
GO_Central		 PMID:20603015 PMID:20603016 PMID:20603073 PMID:24981866 GO_REF:0000033 NCBI chr 1:127,327,098...127,356,807
Ensembl chr 1:117,917,099...117,944,977 		JBrowse link
G Fen1 flap structure-specific endonuclease 1 enables ISO
IEA
IBA		 (PMID:11986308), (PMID:18995831), (PMID:8621570)
GO_REF:0000104
GO_REF:0000107
GO_REF:0000033		 RGD
UniProt
Ensembl
GO_Central		 PMID:8621570 PMID:11986308 PMID:18995831 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 NCBI chr 1:216,270,016...216,274,873
Ensembl chr 1:206,844,884...206,850,003 		JBrowse link
G Gen1 GEN1 Holliday junction 5' flap endonuclease enables ISO
IBA		 (PMID:26578604)
GO_REF:0000033		 RGD
GO_Central		 PMID:26578604 GO_REF:0000033 NCBI chr 6:39,666,675...39,697,480
Ensembl chr 6:33,948,206...33,978,401 		JBrowse link
G Mgme1 mitochondrial genome maintenance exonuclease 1 enables ISO (PMID:27220468) RGD PMID:27220468 NCBI chr 3:152,094,514...152,103,314
Ensembl chr 3:131,640,944...131,649,932 		JBrowse link
G Slc25a16 solute carrier family 25 member 16 enables IEA
IBA
ISS		 GO_REF:0000104
GO_REF:0000107
GO_REF:0000033
GO_REF:0000024		 UniProt
Ensembl
GO_Central		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 NCBI chr20:25,659,847...25,717,080
Ensembl chr20:25,662,055...25,716,319 		JBrowse link
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit enables ISO
IEA
IBA		 (PMID:19596235), (PMID:19596236)
GO_REF:0000002
GO_REF:0000033
GO_REF:0000104		 RGD
InterPro
GO_Central
UniProt		 PMID:19596235 PMID:19596236 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr 1:190,716,759...190,722,307
Ensembl chr 1:181,283,921...181,291,775 		JBrowse link
class II DNA-(apurinic or apyrimidinic site) endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 enables ISO
ISS
IEA		 (PMID:11160897), (PMID:11286553), (PMID:1627644), (PMID:9804798)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:1627644 PMID:9804798 PMID:11160897 PMID:11286553 GO_REF:0000024 GO_REF:0000107 NCBI chr15:26,618,146...26,620,330
Ensembl chr15:24,144,362...24,146,785 		JBrowse link
crossover junction DNA endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eme1 essential meiotic structure-specific endonuclease 1 contributes_to IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:79,586,718...79,595,515
Ensembl chr10:79,586,729...79,595,435 		JBrowse link
G Eme2 essential meiotic structure-specific endonuclease subunit 2 contributes_to IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:14,413,661...14,420,489
Ensembl chr10:13,913,221...13,915,968 		JBrowse link
G Gen1 GEN1 Holliday junction 5' flap endonuclease enables ISO (PMID:23108668), (PMID:26578604), (PMID:26682650), (PMID:28049850) RGD PMID:23108668 PMID:26578604 PMID:26682650 PMID:28049850 NCBI chr 6:39,666,675...39,697,480
Ensembl chr 6:33,948,206...33,978,401 		JBrowse link
G Mus81 MUS81 structure-specific endonuclease subunit enables
contributes_to		 IEA
IBA		 GO_REF:0000104
GO_REF:0000002
GO_REF:0000033		 UniProt
InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr 1:212,219,793...212,225,214
Ensembl chr 1:202,790,466...202,795,843 		JBrowse link
G Rad51c RAD51 paralog C contributes_to
enables		 ISO
IEA
IBA		 (PMID:14716019)
GO_REF:0000107
MGI:3707422|MGI:3707425 (PMID:17312021)
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:14716019 PMID:17312021 GO_REF:0000033 GO_REF:0000107 NCBI chr10:72,702,299...72,728,980
Ensembl chr10:72,205,032...72,231,248 		JBrowse link
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit enables ISO
IBA
IEA		 (PMID:19595721), (PMID:19596235), (PMID:19596236)
GO_REF:0000033
GO_REF:0000104		 RGD
GO_Central
UniProt		 PMID:19595721 PMID:19596235 PMID:19596236 GO_REF:0000033 GO_REF:0000104 NCBI chr 1:190,716,759...190,722,307
Ensembl chr 1:181,283,921...181,291,775 		JBrowse link
G Tefm transcription elongation factor, mitochondrial NOT|enables ISO (PMID:21278163) RGD PMID:21278163 NCBI chr10:65,617,547...65,622,042
Ensembl chr10:65,119,659...65,124,486 		JBrowse link
G Xrcc3 X-ray repair cross complementing 3 contributes_to ISO
IEA		 (PMID:14716019), (PMID:23108668)
GO_REF:0000107		 RGD
Ensembl		 PMID:14716019 PMID:23108668 GO_REF:0000107 NCBI chr 6:136,684,558...136,694,822
Ensembl chr 6:130,863,959...130,872,444 		JBrowse link
deoxyribonuclease I activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dicer1 dicer 1 ribonuclease III enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:129,392,298...129,457,252
Ensembl chr 6:123,631,250...123,693,965 		JBrowse link
G Dnase1 deoxyribonuclease 1 enables IDA
IEA
ISO
IBA		 GO_REF:0000003
(PMID:15015938)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:15015938 PMID:12005024 GO_REF:0000003 GO_REF:0000033, RGD:1298888 NCBI chr10:12,005,305...12,030,615
Ensembl chr10:11,498,931...11,501,869 		JBrowse link
G Dnase1l1 deoxyribonuclease 1-like 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:157,208,230...157,216,812
Ensembl chr  X:152,056,942...152,065,518 		JBrowse link
G Dnase1l2 deoxyribonuclease 1 like 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:13,976,012...13,978,574
Ensembl chr10:13,471,479...13,473,763 		JBrowse link
G Dnase1l3 deoxyribonuclease 1L3 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:19,351,683...19,378,536
Ensembl chr15:16,922,335...16,948,317 		JBrowse link
deoxyribonuclease II activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnase2 deoxyribonuclease 2, lysosomal enables IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
GO_REF:0000003
GO_REF:0000002
(PMID:11375492)
GO_REF:0000104		 GO_Central
Ensembl
UniProt
InterPro
RGD		 PMID:11375492 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 NCBI chr19:40,149,505...40,152,225
Ensembl chr19:23,244,664...23,247,376 		JBrowse link
G Dnase2b deoxyribonuclease 2 beta enables IDA
IEA
IBA		 GO_REF:0000002
GO_REF:0000104
GO_REF:0000033
GO_REF:0000003		 InterPro
UniProt
GO_Central
RGD		 PMID:10558878 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000104, RGD:70721 NCBI chr 2:238,131,182...238,168,041
Ensembl chr 2:235,470,919...235,486,295 		JBrowse link
DNA endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankle1 ankyrin repeat and LEM domain containing 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:18,109,865...18,116,999
Ensembl chr16:18,076,492...18,083,729 		JBrowse link
G Aplf aprataxin and PNKP like factor enables ISO (PMID:17396150) RGD PMID:17396150 NCBI chr 4:121,627,800...121,679,980
Ensembl chr 4:120,070,471...120,122,633 		JBrowse link
G Bivm basic, immunoglobulin-like variable motif containing enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:53,760,885...53,797,125
Ensembl chr 9:46,269,252...46,305,024 		JBrowse link
G Dffb DNA fragmentation factor subunit beta enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:169,804,873...169,817,157
Ensembl chr 5:164,522,463...164,534,628 		JBrowse link
G Dnase1l3 deoxyribonuclease 1L3 IDA RGD PMID:9665719 RGD:728743 NCBI chr15:19,351,683...19,378,536
Ensembl chr15:16,922,335...16,948,317 		JBrowse link
G Dnase2 deoxyribonuclease 2, lysosomal IDA RGD PMID:10558878 RGD:70721 NCBI chr19:40,149,505...40,152,225
Ensembl chr19:23,244,664...23,247,376 		JBrowse link
G Dnase2b deoxyribonuclease 2 beta enables ISO (PMID:10497274) RGD PMID:10497274 NCBI chr 2:238,131,182...238,168,041
Ensembl chr 2:235,470,919...235,486,295 		JBrowse link
G Endog endonuclease G enables ISO
IEA		 (PMID:25355512), (PMID:29719607), (PMID:33473107)
GO_REF:0000107
(PMID:25355512), (PMID:32095813), (PMID:32192768)		 RGD
Ensembl		 PMID:25355512 PMID:29719607 PMID:32095813 PMID:32192768 PMID:33473107 GO_REF:0000107 NCBI chr 3:33,846,935...33,849,531
Ensembl chr 3:13,449,086...13,451,932 		JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit contributes_to
enables		 ISO
IEA		 (PMID:8797827)
GO_REF:0000002
(PMID:10413517), (PMID:14734547), (PMID:17055345)		 RGD
InterPro		 PMID:8797827 PMID:10413517 PMID:14734547 PMID:17055345 GO_REF:0000002 NCBI chr10:2,926,085...2,958,176
Ensembl chr10:2,419,038...2,448,369
Ensembl chr10:2,419,038...2,448,369 		JBrowse link
G Ercc4l1 excision repair cross-complementing rodent repair deficiency, complementation group 4-like 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:954,927...983,651
Ensembl chr10:954,977...983,174 		JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease enables ISO
IBA		 (PMID:12644470), (PMID:8090225)
GO_REF:0000033		 RGD
GO_Central		 PMID:8090225 PMID:12644470 GO_REF:0000033 NCBI chr 9:53,801,471...53,846,611
Ensembl chr 9:46,309,389...46,354,472 		JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease enables ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000002
(PMID:22078559), (PMID:23080121), (PMID:24316220), (PMID:27814491), (PMID:27889449), (PMID:30787182), (PMID:9705271)		 UniProt
InterPro
RGD		 PMID:9705271 PMID:22078559 PMID:23080121 PMID:24316220 PMID:27814491 More... GO_REF:0000002 GO_REF:0000024 NCBI chr 8:19,900,211...19,961,906
Ensembl chr 8:11,632,354...11,678,279 		JBrowse link
G N4bp2 NEDD4 binding protein 2 enables ISO
IEA		 (PMID:12730195)
GO_REF:0000107		 RGD
Ensembl		 PMID:12730195 GO_REF:0000107 NCBI chr14:42,342,690...42,479,861
Ensembl chr14:42,409,510...42,483,960 		JBrowse link
G Rps3 ribosomal protein S3 enables ISO (PMID:15707971), (PMID:20605787) RGD PMID:15707971 PMID:20605787 NCBI chr 1:163,190,476...163,195,885
Ensembl chr 1:153,777,472...153,783,680 		JBrowse link
G Zranb3 zinc finger RANBP2-type containing 3 enables ISO
IBA		 (PMID:22759634)
GO_REF:0000033		 RGD
GO_Central		 PMID:22759634 GO_REF:0000033 NCBI chr13:41,993,110...42,148,298
Ensembl chr13:39,440,889...39,595,670 		JBrowse link
DNA endonuclease activity, producing 5'-phosphomonoesters term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Endov endonuclease V NOT|enables ISO (PMID:23139746), (PMID:23912683)
(PMID:12853604)		 RGD PMID:12853604 PMID:23139746 PMID:23912683 NCBI chr10:104,760,059...104,777,732
Ensembl chr10:104,760,137...104,775,969 		JBrowse link
double-stranded DNA endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eme1 essential meiotic structure-specific endonuclease 1 contributes_to IEA
ISO		 GO_REF:0000107
(PMID:35290797)		 Ensembl
RGD		 PMID:35290797 GO_REF:0000107 NCBI chr10:79,586,718...79,595,515
Ensembl chr10:79,586,729...79,595,435 		JBrowse link
G Eme2 essential meiotic structure-specific endonuclease subunit 2 contributes_to IEA
ISO		 GO_REF:0000107
(PMID:35290797)		 Ensembl
RGD		 PMID:35290797 GO_REF:0000107 NCBI chr10:14,413,661...14,420,489
Ensembl chr10:13,913,221...13,915,968 		JBrowse link
G Mus81 MUS81 structure-specific endonuclease subunit enables IEA
ISO		 GO_REF:0000107
(PMID:35290797)		 Ensembl
RGD		 PMID:35290797 GO_REF:0000107 NCBI chr 1:212,219,793...212,225,214
Ensembl chr 1:202,790,466...202,795,843 		JBrowse link
G Rag1 recombination activating 1 contributes_to IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:108,372,087...108,383,184
Ensembl chr 3:87,917,004...87,928,291 		JBrowse link
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snd1 staphylococcal nuclease and tudor domain containing 1 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 4:58,060,689...58,459,926
Ensembl chr 4:57,095,208...57,530,843 		JBrowse link
endoribonuclease activity, cleaving miRNA-paired mRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ago2 argonaute RISC catalytic component 2 enables IEA
ISO		 GO_REF:0000107
(PMID:15260970), (PMID:22795694)		 Ensembl
RGD		 PMID:15260970 PMID:22795694 GO_REF:0000107 NCBI chr 7:106,907,209...106,994,124
Ensembl chr 7:105,029,120...105,104,974 		JBrowse link
G Ago3 argonaute RISC catalytic component 3 enables ISO (PMID:29040713) RGD PMID:29040713 NCBI chr 5:138,632,367...138,714,230
Ensembl chr 5:138,639,569...138,714,230 		JBrowse link
endoribonuclease activity, cleaving siRNA-paired mRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ago2 argonaute RISC catalytic component 2 enables IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000002
GO_REF:0000024
(PMID:15260970), (PMID:17524464)		 Ensembl
InterPro
UniProt
RGD		 PMID:15260970 PMID:17524464 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:106,907,209...106,994,124
Ensembl chr 7:105,029,120...105,104,974 		JBrowse link
endoribonuclease inhibitor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abce1 ATP binding cassette subfamily E member 1 enables ISO
IEA		 (PMID:7539425)
GO_REF:0000107		 RGD
Ensembl		 PMID:7539425 GO_REF:0000107 NCBI chr19:45,109,880...45,134,819
Ensembl chr19:28,205,555...28,230,489 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 enables ISO
IBA		 (PMID:19328063)
GO_REF:0000033		 RGD
GO_Central		 PMID:19328063 GO_REF:0000033 NCBI chr 7:132,405,217...132,422,492
Ensembl chr 7:130,527,316...130,543,633 		JBrowse link
flap endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Exo1 exonuclease 1 enables ISO
IEA		 (PMID:10608837), (PMID:11842105)
GO_REF:0000107		 RGD
Ensembl		 PMID:10608837 PMID:11842105 GO_REF:0000107 NCBI chr13:90,341,947...90,366,861
Ensembl chr13:87,809,810...87,834,654 		JBrowse link
G Fen1 flap structure-specific endonuclease 1 enables ISO
IEA		 (PMID:18499658)
GO_REF:0000107
(PMID:12162748)		 RGD
Ensembl		 PMID:12162748 PMID:18499658 GO_REF:0000107 NCBI chr 1:216,270,016...216,274,873
Ensembl chr 1:206,844,884...206,850,003 		JBrowse link
phosphodiesterase decapping endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt12 nudix hydrolase 12 enables ISO
IEA		 (PMID:31875550)
GO_REF:0000107		 RGD
Ensembl		 PMID:31875550 GO_REF:0000107 NCBI chr 9:98,741,627...98,755,039
Ensembl chr 9:98,742,360...98,755,039 		JBrowse link
G Nudt16 nudix hydrolase 16 enables ISO
IBA		 (PMID:29483298)
GO_REF:0000033		 RGD
GO_Central		 PMID:29483298 GO_REF:0000033 NCBI chr 8:105,739,927...105,741,982
Ensembl chr 8:105,739,623...105,741,998 		JBrowse link
G Nudt16l1 nudix hydrolase 16 like 1 NOT|enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:10,636,174...10,638,090
Ensembl chr10:10,636,174...10,688,370 		JBrowse link
G Nudt16l2 nudix hydrolase 16 like 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:105,754,821...105,756,548
Ensembl chr 8:105,754,844...105,756,518 		JBrowse link
ribonuclease A activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnase1 ribonuclease A family member 1, pancreatic enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr15:24,361,924...24,363,633
Ensembl chr15:24,361,927...24,363,624 		JBrowse link
G Rnase1l1 ribonuclease, RNase A family, 1-like 1 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr15:24,338,216...24,339,934
Ensembl chr15:24,338,479...24,338,931 		JBrowse link
G Rnase1l2 ribonuclease, RNase A family, 1-like 2 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr15:24,421,825...24,423,513
Ensembl chr15:24,421,859...24,423,611 		JBrowse link
ribonuclease III activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dicer1 dicer 1 ribonuclease III enables ISO
IEA
IBA		 (PMID:12411504), (PMID:12411505), (PMID:21753850)
GO_REF:0000002
GO_REF:0000003
GO_REF:0000033		 RGD
InterPro
UniProt
GO_Central		 PMID:12411504 PMID:12411505 PMID:21753850 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr 6:129,392,298...129,457,252
Ensembl chr 6:123,631,250...123,693,965 		JBrowse link
G Drosha drosha ribonuclease III enables ISO
IEA
IBA		 (PMID:14508493), (PMID:15574589)
GO_REF:0000002
GO_REF:0000107
GO_REF:0000033		 RGD
InterPro
Ensembl
GO_Central		 PMID:14508493 PMID:15574589 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:63,591,885...63,703,688
Ensembl chr 2:61,864,970...61,976,688 		JBrowse link
G Mrpl44 mitochondrial ribosomal protein L44 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:88,555,050...88,560,101
Ensembl chr 9:81,106,655...81,112,812 		JBrowse link
ribonuclease MRP activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpp40 ribonuclease P/MRP subunit p40 contributes_to IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:28,947,752...28,956,788
Ensembl chr17:28,947,734...28,956,788 		JBrowse link
ribonuclease P activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pop1 POP1 homolog, ribonuclease P/MRP subunit contributes_to ISO
IEA		 (PMID:30454648), (PMID:8918471)
GO_REF:0000107		 RGD
Ensembl		 PMID:8918471 PMID:30454648 GO_REF:0000107 NCBI chr 7:65,705,348...65,733,143
Ensembl chr 7:65,705,368...65,733,141 		JBrowse link
G Pop4 POP4 homolog, ribonuclease P/MRP subunit contributes_to
enables		 ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000003
(PMID:30454648)		 UniProt
RGD		 PMID:30454648 GO_REF:0000003 GO_REF:0000024 NCBI chr 1:100,096,722...100,105,056
Ensembl chr 1:90,960,022...90,968,443 		JBrowse link
G Pop5 POP5 homolog, ribonuclease P/MRP subunit contributes_to
enables		 ISO
IEA		 (PMID:30454648)
GO_REF:0000107
GO_REF:0000003
(PMID:11413139)		 RGD
Ensembl
UniProt		 PMID:11413139 PMID:30454648 GO_REF:0000003 GO_REF:0000107 NCBI chr12:41,376,755...41,384,882
Ensembl chr12:41,376,755...41,381,336 		JBrowse link
G Pop7 POP7 homolog, ribonuclease P/MRP subunit contributes_to
enables		 ISO
IEA		 (PMID:30454648)
GO_REF:0000003
GO_REF:0000104		 RGD
UniProt		 PMID:30454648 GO_REF:0000003 GO_REF:0000104 NCBI chr12:19,189,384...19,190,425
Ensembl chr12:19,189,138...19,190,674 		JBrowse link
G Prorp protein only RNase P catalytic subunit enables ISS
IEA
IBA
ISO		 GO_REF:0000024
GO_REF:0000003
GO_REF:0000107
GO_REF:0000033
(PMID:25953853)		 UniProt
Ensembl
GO_Central
RGD		 PMID:25953853 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:78,404,821...78,497,562
Ensembl chr 6:72,670,847...72,762,416 		JBrowse link
G Rpp14 ribonuclease P/MRP subunit p14 contributes_to
enables		 ISO
IEA		 (PMID:30454648)
GO_REF:0000003		 RGD
UniProt		 PMID:30454648 GO_REF:0000003 NCBI chr15:16,837,796...16,847,970
Ensembl chr15:16,836,859...16,852,101
Ensembl chr15:16,836,859...16,852,101 		JBrowse link
G Rpp21 ribonuclease P/MRP subunit p21 contributes_to ISO (PMID:30454648) RGD PMID:30454648 NCBI chr20:1,986,225...2,025,308
Ensembl chr20:2,018,147...2,020,106 		JBrowse link
G Rpp25 ribonuclease P and MRP subunit p25 contributes_to
enables		 ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
GO_REF:0000003
(PMID:30454648)		 UniProt
Ensembl
RGD		 PMID:30454648 GO_REF:0000003 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:57,907,352...57,908,732
Ensembl chr 8:57,907,352...57,908,732 		JBrowse link
G Rpp30 ribonuclease P/MRP subunit p30 contributes_to ISO
IEA		 (PMID:30454648)
GO_REF:0000107		 RGD
Ensembl		 PMID:30454648 GO_REF:0000107 NCBI chr 1:233,786,048...233,808,958
Ensembl chr 1:233,786,099...233,808,952 		JBrowse link
G Rpp38 ribonuclease P/MRP subunit p38 contributes_to ISO
IEA
IBA		 (PMID:30454648)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:30454648 GO_REF:0000033 GO_REF:0000107 NCBI chr17:79,823,237...79,826,908
Ensembl chr17:74,908,932...74,927,431 		JBrowse link
G Rpp40 ribonuclease P/MRP subunit p40 contributes_to
enables		 ISO
IEA
IBA		 (PMID:30454648)
GO_REF:0000003
GO_REF:0000107
GO_REF:0000033		 RGD
UniProt
Ensembl
GO_Central		 PMID:30454648 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 NCBI chr17:28,947,752...28,956,788
Ensembl chr17:28,947,734...28,956,788 		JBrowse link
ribonuclease T2 activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnaset2 ribonuclease T2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:52,576,344...52,603,151
Ensembl chr 1:52,585,929...52,603,147 		JBrowse link
G Rnaset2-ps1 ribonuclease T2, pseudogene 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:138,600,084...138,600,943
Ensembl chr 3:138,600,187...138,600,965
Ensembl chr 3:138,600,187...138,600,965 		JBrowse link
RNA endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC118772.1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr10:68,067,119...68,089,948 JBrowse link
G Ago1 argonaute RISC component 1 NOT|enables ISO (PMID:23809764) RGD PMID:23809764 NCBI chr 5:144,006,618...144,064,740
Ensembl chr 5:138,722,111...138,773,546 		JBrowse link
G Ago2 argonaute RISC catalytic component 2 enables ISO
IEA
IBA		 (PMID:18178619)
GO_REF:0000107
GO_REF:0000033
(PMID:20424607)		 RGD
Ensembl
GO_Central		 PMID:18178619 PMID:20424607 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:106,907,209...106,994,124
Ensembl chr 7:105,029,120...105,104,974 		JBrowse link
G Ago3 argonaute RISC catalytic component 3 enables ISO
IEA
IBA		 (PMID:29040713)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:29040713 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:138,632,367...138,714,230
Ensembl chr 5:138,639,569...138,714,230 		JBrowse link
G Ago4 argonaute RISC component 4 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:138,780,446...138,825,898
Ensembl chr 5:138,783,069...138,825,632 		JBrowse link
G Ankzf1 ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1 enables ISO
IEA
ISS		 (PMID:30244831), (PMID:31011209)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:30244831 PMID:31011209 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:84,136,862...84,143,830
Ensembl chr 9:76,688,194...76,696,469 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 IDA RGD PMID:19401441 RGD:2315668 NCBI chr15:26,618,146...26,620,330
Ensembl chr15:24,144,362...24,146,785 		JBrowse link
G Bacc1 BPTF associated chromatin complex component 1 enables IBA
IEA		 GO_REF:0000033
GO_REF:0000002		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr10:54,951,991...54,954,756
Ensembl chr10:54,951,991...54,956,601 		JBrowse link
G Cpsf3 cleavage and polyadenylation specific factor 3 enables ISO
IEA
IBA		 (PMID:30507380)
GO_REF:0000107
GO_REF:0000033
(PMID:18955505)		 RGD
Ensembl
GO_Central		 PMID:18955505 PMID:30507380 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:40,836,121...40,864,129
Ensembl chr 6:40,836,097...40,864,128 		JBrowse link
G Dicer1 dicer 1 ribonuclease III enables ISO (PMID:18325616), (PMID:19701182), (PMID:25549615) RGD PMID:18325616 PMID:19701182 PMID:25549615 NCBI chr 6:129,392,298...129,457,252
Ensembl chr 6:123,631,250...123,693,965 		JBrowse link
G Drosha drosha ribonuclease III enables ISO
IEA		 (PMID:20424607)
GO_REF:0000117
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:20424607 GO_REF:0000107 GO_REF:0000117 NCBI chr 2:63,591,885...63,703,688
Ensembl chr 2:61,864,970...61,976,688 		JBrowse link
G Endou endonuclease, poly(U)-specific enables ISO
IEA
IBA		 FB:FBgn0030251 (PMID:18936097), (PMID:37803019)
GO_REF:0000002
GO_REF:0000104
GO_REF:0000033		 RGD
InterPro
UniProt
GO_Central		 PMID:18936097 PMID:37803019 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr 7:130,723,972...130,745,672
Ensembl chr 7:128,844,862...128,866,596 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 enables ISO
IEA
IBA		 (PMID:11779465), (PMID:19328063), (PMID:21317875), (PMID:9637683)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000033
(PMID:15601821), (PMID:25164867)		 RGD
Ensembl
InterPro
GO_Central		 PMID:9637683 PMID:11779465 PMID:15601821 PMID:19328063 PMID:21317875 More... GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Ern2 endoplasmic reticulum to nucleus signaling 2 enables IBA
IEA		 GO_REF:0000033
GO_REF:0000002		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:186,153,115...186,174,521
Ensembl chr 1:176,726,454...176,743,289 		JBrowse link
G Exog exo/endonuclease G enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:128,062,688...128,082,529
Ensembl chr 8:119,185,136...119,204,672 		JBrowse link
G Ints11 integrator complex subunit 11 enables IEA
ISO
ISS
IBA		 GO_REF:0000107
(PMID:16239144), (PMID:32697989), (PMID:33243860), (PMID:33548203), (PMID:34762484), (PMID:37080207), (PMID:38570683), (PMID:39032489)
GO_REF:0000024
GO_REF:0000033		 Ensembl
RGD
UniProt
GO_Central		 PMID:16239144 PMID:32697989 PMID:33243860 PMID:33548203 PMID:34762484 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:171,761,370...171,779,883
Ensembl chr 5:166,479,155...166,497,651 		JBrowse link
G Khnyn KH and NYN domain containing enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:33,335,290...33,349,553
Ensembl chr15:29,365,260...29,376,967 		JBrowse link
G Lactb2 lactamase, beta 2 enables ISS
IEA
IBA
ISO		 GO_REF:0000024
GO_REF:0000107
GO_REF:0000033
(PMID:26826708)		 UniProt
Ensembl
GO_Central
RGD		 PMID:26826708 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:10,352,165...10,374,928
Ensembl chr 5:5,569,067...5,596,429 		JBrowse link
G Mblac1 metallo-beta-lactamase domain containing 1 enables ISO
IEA
ISS		 (PMID:30507380)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:30507380 GO_REF:0000024 GO_REF:0000107 NCBI chr12:17,071,465...17,072,736
Ensembl chr12:17,071,465...17,072,735 		JBrowse link
G Nob1 NIN1 (RPN12) binding protein 1 homolog enables ISO
IEA
IBA		 (PMID:23439679), (PMID:23482395)
GO_REF:0000002
GO_REF:0000033
GO_REF:0000104		 RGD
InterPro
GO_Central
UniProt		 PMID:23439679 PMID:23482395 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr19:35,322,803...35,335,354
Ensembl chr19:35,322,669...35,346,815 		JBrowse link
G Nynrin NYN domain and retroviral integrase containing enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:33,302,778...33,325,120
Ensembl chr15:29,332,869...29,355,215 		JBrowse link
G Piwil1 piwi-like RNA-mediated gene silencing 1 enables ISO
IEA
IBA		 (PMID:22121019), (PMID:25582079)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:22121019 PMID:25582079 GO_REF:0000033 GO_REF:0000107 NCBI chr12:33,585,747...33,606,715
Ensembl chr12:27,949,744...27,970,580 		JBrowse link
G Piwil2 piwi-like RNA-mediated gene silencing 2 enables ISO
IBA		 (PMID:22020280), (PMID:23706823), (PMID:28633017)
GO_REF:0000033		 RGD
GO_Central		 PMID:22020280 PMID:23706823 PMID:28633017 GO_REF:0000033 NCBI chr15:51,841,104...51,907,729
Ensembl chr15:45,431,703...45,497,702 		JBrowse link
G Piwil4 piwi-like RNA-mediated gene silencing 4 NOT|enables ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:22020280)		 UniProt
GO_Central
RGD		 PMID:22020280 GO_REF:0000024 GO_REF:0000033 NCBI chr 8:19,817,985...19,861,327
Ensembl chr 8:11,536,520...11,579,761 		JBrowse link
G Ppp1r8 protein phosphatase 1, regulatory subunit 8 enables ISO (PMID:10432294), (PMID:9153239) RGD PMID:9153239 PMID:10432294 NCBI chr 5:145,031,632...145,048,753
Ensembl chr 5:145,031,498...145,048,752 		JBrowse link
G Rcl1 RNA terminal phosphate cyclase-like 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:236,238,078...236,282,597
Ensembl chr 1:226,824,534...226,902,315 		JBrowse link
G Rnasek ribonuclease K enables ISO
IEA
IBA		 (PMID:17881363)
GO_REF:0000002
GO_REF:0000033		 RGD
InterPro
GO_Central		 PMID:17881363 GO_REF:0000002 GO_REF:0000033 NCBI chr10:54,954,904...54,956,622
Ensembl chr10:54,951,991...54,956,601 		JBrowse link
G Rnaset2 ribonuclease T2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:52,576,344...52,603,151
Ensembl chr 1:52,585,929...52,603,147 		JBrowse link
G Rnaset2-ps1 ribonuclease T2, pseudogene 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:138,600,084...138,600,943
Ensembl chr 3:138,600,187...138,600,965
Ensembl chr 3:138,600,187...138,600,965 		JBrowse link
G Slfn14 schlafen family member 14 enables ISO (PMID:25996083) RGD PMID:25996083 NCBI chr10:68,076,326...68,087,794 JBrowse link
G Slfn9 schlafen family member 9 enables IDA PMID:29563550 UniProt PMID:29563550 RGD:13601999 NCBI chr10:68,406,641...68,420,062
Ensembl chr10:67,909,106...67,925,383 		JBrowse link
G Smg6 SMG6 nonsense mediated mRNA decay factor enables ISO
IEA		 (PMID:18974281), (PMID:19060897)
GO_REF:0000107		 RGD
Ensembl		 PMID:18974281 PMID:19060897 GO_REF:0000107 NCBI chr10:60,284,628...60,512,738
Ensembl chr10:59,786,258...60,014,395 		JBrowse link
G Snd1 staphylococcal nuclease and tudor domain containing 1 enables ISO
IEA		 (PMID:28546213)
GO_REF:0000107
GO_REF:0000104		 RGD
Ensembl
UniProt		 PMID:28546213 GO_REF:0000104 GO_REF:0000107 NCBI chr 4:58,060,689...58,459,926
Ensembl chr 4:57,095,208...57,530,843 		JBrowse link
G Tsnax translin-associated factor X enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:52,975,848...52,989,886
Ensembl chr19:52,975,659...52,989,878 		JBrowse link
G Ybey ybeY metalloendoribonuclease enables ISO
IEA		 (PMID:28153719)
GO_REF:0000107		 RGD
Ensembl		 PMID:28153719 GO_REF:0000107 NCBI chr20:12,165,192...12,174,713
Ensembl chr20:12,165,237...12,174,713 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A enables ISS
IEA
ISO
IBA		 GO_REF:0000024
GO_REF:0000107
(PMID:22055188), (PMID:26000482), (PMID:26255671)
GO_REF:0000033		 UniProt
Ensembl
RGD
GO_Central		 PMID:22055188 PMID:26000482 PMID:26255671 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:142,661,193...142,670,051
Ensembl chr 5:137,376,564...137,385,351 		JBrowse link
G Zc3h12b zinc finger CCCH-type containing 12B enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:60,615,616...60,849,278
Ensembl chr  X:60,615,682...60,844,832 		JBrowse link
G Zc3h12c zinc finger CCCH type containing 12C enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:61,340,446...61,404,932
Ensembl chr 8:52,448,320...52,504,315 		JBrowse link
G Zc3h12d zinc finger CCCH type containing 12D enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:4,131,674...4,169,192
Ensembl chr 1:2,314,324...2,348,819 		JBrowse link
RNA endonuclease activity, producing 3'-phosphomonoesters term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rida reactive intermediate imine deaminase A homolog IDA RGD PMID:10400702 RGD:9685547 NCBI chr 7:67,576,586...67,590,493
Ensembl chr 7:65,691,435...65,705,716 		JBrowse link
RNA endonuclease activity, producing 5'-phosphomonoesters term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ago2 argonaute RISC catalytic component 2 enables IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 7:106,907,209...106,994,124
Ensembl chr 7:105,029,120...105,104,974 		JBrowse link
G Dicer1 dicer 1 ribonuclease III enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:129,392,298...129,457,252
Ensembl chr 6:123,631,250...123,693,965 		JBrowse link
G Elac1 elaC ribonuclease Z 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr18:69,596,475...69,617,206
Ensembl chr18:67,323,583...67,340,936 		JBrowse link
G Endov endonuclease V enables ISO
IEA
IBA		 (PMID:23912683), (PMID:23912718), (PMID:27573237)
GO_REF:0000107
GO_REF:0000033
(PMID:3170309)		 RGD
Ensembl
GO_Central		 PMID:3170309 PMID:23912683 PMID:23912718 PMID:27573237 GO_REF:0000033 GO_REF:0000107 NCBI chr10:104,760,059...104,777,732
Ensembl chr10:104,760,137...104,775,969 		JBrowse link
G Pld6 phospholipase D family, member 6 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:45,078,081...45,080,732
Ensembl chr10:44,577,675...44,581,077 		JBrowse link
RNA lariat debranching enzyme activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cwf19l1 CWF19 like cell cycle control factor 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:242,997,720...243,020,989
Ensembl chr 1:242,997,726...243,020,961 		JBrowse link
RNA lariat debranching enzyme activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbr1 debranching RNA lariats 1 enables ISO
IEA		 (PMID:10982890), (PMID:29474921)
GO_REF:0000117		 RGD
UniProt		 PMID:10982890 PMID:29474921 GO_REF:0000117 NCBI chr 8:100,139,039...100,150,768
Ensembl chr 8:100,139,034...100,151,030 		JBrowse link
RNA-DNA hybrid ribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENSRNOG00000067229 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 4:83,921,470...83,930,590 JBrowse link
G ENSRNOG00000067248 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 9:77,055,483...77,060,879 JBrowse link
G ENSRNOG00000069624 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 4:147,700,824...147,706,682 JBrowse link
G Fen1 flap structure-specific endonuclease 1 enables ISO
IEA
IBA		 (PMID:7961795)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:7961795 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:216,270,016...216,274,873
Ensembl chr 1:206,844,884...206,850,003 		JBrowse link
G Nynrin NYN domain and retroviral integrase containing enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr15:33,302,778...33,325,120
Ensembl chr15:29,332,869...29,355,215 		JBrowse link
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:48,243,365...48,253,316
Ensembl chr 9:48,237,572...48,253,211 		JBrowse link
G Rnaseh1 ribonuclease H1 enables ISO
IEA
IBA
ISS		 (PMID:21700224)
GO_REF:0000117
GO_REF:0000002
GO_REF:0000107
GO_REF:0000003
(PMID:15831789)
GO_REF:0000033
GO_REF:0000024		 RGD
UniProt
InterPro
Ensembl
GO_Central		 PMID:15831789 PMID:21700224 GO_REF:0000002 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr 6:45,282,849...45,292,258
Ensembl chr 6:45,282,854...45,292,236 		JBrowse link
G Rnaseh2a ribonuclease H2, subunit A enables ISO
IEA
IBA
ISS		 (PMID:21177858)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000003
GO_REF:0000033
GO_REF:0000024		 RGD
Ensembl
InterPro
UniProt
GO_Central		 PMID:21177858 GO_REF:0000002 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr19:23,186,325...23,196,045
Ensembl chr19:23,186,383...23,196,041 		JBrowse link
G Thsd8 thrombospondin type 1 domain containing 8 enables IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr19:23,186,394...23,188,323
Ensembl chr19:23,186,364...23,196,042 		JBrowse link
single-stranded DNA endodeoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aste1 asteroid homolog 1 enables ISO
IEA		 (PMID:34354233)
GO_REF:0000107		 RGD
Ensembl		 PMID:34354233 GO_REF:0000107 NCBI chr 8:114,905,349...114,923,775
Ensembl chr 8:106,026,515...106,044,430 		JBrowse link
G Dclre1c DNA cross-link repair 1C enables ISO (PMID:11955432) RGD PMID:11955432 NCBI chr17:74,775,828...74,810,089
Ensembl chr17:74,776,935...74,809,186 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit contributes_to ISO (PMID:7559382) RGD PMID:7559382 NCBI chr 1:88,099,308...88,135,966
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:2,926,085...2,958,176
Ensembl chr10:2,419,038...2,448,369
Ensembl chr10:2,419,038...2,448,369 		JBrowse link
G Ercc4l1 excision repair cross-complementing rodent repair deficiency, complementation group 4-like 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:954,927...983,651
Ensembl chr10:954,977...983,174 		JBrowse link
G Exog exo/endonuclease G enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:128,062,688...128,082,529
Ensembl chr 8:119,185,136...119,204,672 		JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease enables ISO
IBA		 (PMID:9705271)
GO_REF:0000033		 RGD
GO_Central		 PMID:9705271 GO_REF:0000033 NCBI chr 8:19,900,211...19,961,906
Ensembl chr 8:11,632,354...11,678,279 		JBrowse link
G Ptbp1 polypyrimidine tract binding protein 1 IDA RGD PMID:12269805 RGD:633791 NCBI chr 7:10,493,199...10,502,957
Ensembl chr 7:9,842,574...9,852,397 		JBrowse link
G Rad50 RAD50 double strand break repair protein contributes_to ISO
IEA
ISS		 (PMID:9705271)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:9705271 GO_REF:0000024 GO_REF:0000107 NCBI chr10:38,310,147...38,362,100
Ensembl chr10:37,808,726...37,861,396 		JBrowse link
G Rbbp8 RB binding protein 8, endonuclease enables ISO
IEA		 (PMID:18716619), (PMID:19202191)
GO_REF:0000107		 RGD
Ensembl		 PMID:18716619 PMID:19202191 GO_REF:0000107 NCBI chr18:3,198,188...3,263,643
Ensembl chr18:2,921,286...2,988,846 		JBrowse link
G Setmar SET domain and mariner transposase fusion gene enables ISO (PMID:21491884), (PMID:24573677) RGD PMID:21491884 PMID:24573677 NCBI chr 4:142,602,066...142,614,208
Ensembl chr 4:141,046,069...141,058,197 		JBrowse link
site-specific endodeoxyribonuclease activity, specific for altered base term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 enables ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19188445), (PMID:24703901)		 UniProt
Ensembl
RGD		 PMID:19188445 PMID:24703901 GO_REF:0000024 GO_REF:0000107 NCBI chr15:26,618,146...26,620,330
Ensembl chr15:24,144,362...24,146,785 		JBrowse link
G Dna2 DNA replication helicase/nuclease 2 enables IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:25,661,652...25,690,598
Ensembl chr20:25,662,055...25,716,319 		JBrowse link
G Slc25a16 solute carrier family 25 member 16 enables IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:25,659,847...25,717,080
Ensembl chr20:25,662,055...25,716,319 		JBrowse link
tRNA-intron lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tsen2 tRNA splicing endonuclease subunit 2 enables IEA
IBA		 GO_REF:0000002
GO_REF:0000003
GO_REF:0000033		 InterPro
UniProt
GO_Central		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr 4:150,275,389...150,310,846
Ensembl chr 4:148,602,863...148,638,215 		JBrowse link
G Tsen34 tRNA splicing endonuclease subunit 34 enables IBA
IEA		 GO_REF:0000033
GO_REF:0000003
GO_REF:0000104
GO_REF:0000002		 GO_Central
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000104 NCBI chr 1:65,517,324...65,525,194
Ensembl chr 1:65,517,330...65,524,412 		JBrowse link
Term paths to the root